Clinical trials: Satiety Hormones
Obesity
ACE Stapler Sub Study
Obesity and its associated conditions have reached epidemic proportions. Estimates are that about one third of the adults in the United States have obesity.
- Trial name
- NCT02381340
- Testing
- ACE stapling procedure
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Maastricht University Medical Center
Obesity, Overweight
Effect of Food Temperature and Diet Composition on Satiety, Satiety Hormones, Chewing Time and Neuronal Activity
Obesity and its related illnesses have become serious health issues, obesity is today the fifth most common cause of death. Obesity rate has dramatically enhanced in both male and female, and across all ages.
- Trial name
- NCT05822167
- Testing
- High Protein Meal at Cold Temperature, High Protein Meal at Warm Temperarute, High Protein Meal at Hot Temperature
- Where
- Pakistan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Change of Gastric pH
Influence of a Bitter Compound and Bittermasking Compound on Gastric pH
The purpose of this study is to elucidate whether bitter taste induced by the bitter compound caffeine and the reduction of bitter taste by addition of the bitter masking compound Homoeriodictyol sodium salt (HED) influence…
- Trial name
- NCT02372188
- Testing
- water, caffeine, caffein + homoeriodictyol sodium salt
- Where
- Austria
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Obesity, Overweight
Availability of Lipids in Almonds in Healthy Individuals
Evidence indicates that almond consumption is associated with multiple health benefits. However, nuts are commonly excluded from diets on the basis that their high energy content may induce weight gain.
- Trial name
- NCT00768417
- Testing
- 10 chews, 25 Chews, 40 Chews
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Appetite
Cereal-based Products Fortified With Legumes and Effects on Glycemic Control and Appetite Regulation
Legumes are rich source of proteins and dietary fibers which are associated with satiety and amelioration of postprandial glycemic response.
- Trial name
- NCT03974165
- Testing
- Cereal-legume product 1, Cereal-legume product 2, Cereal product
- Where
- Greece
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Healthy Adult
The Effects of Palm Olein and Palm Kernel Oil Diets on Gut Hormones and Appetite in Healthy Adults
The goal of this clinical trial is to investigate the postprandial effect of palm olein- and palm kernel oil- diets compared to PUFA-rich diet (sunflower oil in this study) on gut hormones response and appetite in healthy adults.
- Trial name
- NCT07541300
- Testing
- Palm olein, Palm kernel oil, Sunflower Oil
- Where
- Malaysia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Esophageal Cancer, Nutrition Disorders
Gastrointestinal Nutrient Transit and Enteroendocrine Function After Upper Gastrointestinal Surgery
The incidence of oesophagogastric cancer has increased by 400% since the 1970s in Ireland and the United Kingdom. In addition, refinement of perioperative management and the now widespread use of multimodal protocols for patients…
- Conditions
- Esophageal Cancer, Nutrition Disorders, Appetite Disorders, Dumping Syndrome
- Trial name
- EndoGut (NCT03734627)
- Testing
- Octreotide Acetate, Saline Solution, Paracetamol
- Where
- 2 sites in Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Hunger
A Study of Chewing Gum, Snacking and Appetite
Investigators are interested in learning how appetite responds after chewing gum. In this research study subjects will be asked to eat a lunch meal provided at our Center.
- Trial name
- GUM (NCT01316991)
- Testing
- Chewing Gum, No Gum
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Obesity, Food Craving
Transcranial Magnetic Stimulation (TMS) in Obesity
Obesity is a metabolic disease that has reached epidemic proportions. Insofar no long-term effective drug treatment was developed for obesity.
- Conditions
- Obesity, Food Craving, Appetite and General Nutritional Disorders
- Trial name
- NCT03009695
- Testing
- High frequency repetitive dTMS, Low frequency repetitive dTMS
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Ospedale San Donato
Obesity
Prebiotic Fiber as a Modifier of Satiety Hormones and Body Weight in Overweight and Obese Adults
The purpose of this study is to determine if oligofructose supplementation promotes weight loss in overweight and obese adults.
- Trial name
- NCT00522353
- Testing
- Oligofructose
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Overweight and Obesity
Evaluation of Libramed in Obesity Treatment
Randomized, double-blind, placebo-controlled study aimed at evaluating the effects of a 3-months treatment with Policaptil Gel Retard on postprandial incretin hormones release and satiety in obese women
- Trial name
- ELOT (NCT03537235)
- Testing
- Libramed
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Aboca Spa Societa' Agricola
Obesity, Hormone Responses
Effect of Gastric Bypass Surgery on Brain Responses
After obesity surgery gastric bypass (GBP) patients usually lose more than 50% of its former preponderance in relative short time (~ 2 years).
- Conditions
- Obesity, Hormone Responses, Cognitive Health
- Trial name
- NCT01815216
- Testing
- Bariatric surgery, Brain activity in resting state, Memory performance
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Uppsala University
Overweight and Obesity
Satiety Innovation- Study 793. University of Aberdeen
The proposed study will address the effect of developed novel food products through processing innovation on motivation to eat, biomarkers of satiety, nutrient bioavailability and gut health using in vivo studies and validating…
- Trial name
- SATIN (NCT01724411)
- Testing
- Resistant Starch type 3
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- P Burns
Overweight, Diabetes
Functional Ingredients: Effect in Gastrointestinal System
The addition of fructans or unripe banana flour to frozen meals can change the hormonal parameters related to hunger and satiety, improve the bowel movements and increase in colonic bacteria population measured by microbiological…
- Conditions
- Overweight, Diabetes, Constipation
- Trial name
- NCT02467972
- Testing
- Ready-to-eat frozen soups added unripe banana flour, Ready-to-eat frozen soups added maltodextrin, Ready-to-eat frozen soups added inulin
- Where
- Brazil
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Healthy Male Subjects
Properties of Dietary Fibre and Energy Intake
Dietary fibers likely have a role in body weight management. They may increase satiety and, as a consequence, reduce energy intake during the next meal.
- Trial name
- ProVe (NCT01257295)
- Testing
- control: no fiber addition, breakfast with low viscous, low gelling pectin, high viscous, low gelling pectin
- Where
- Netherlands
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Wageningen University
PYY, Ghrelin
The Effect of Breakfast With Different Macronutrient Composition on PYY, Ghrelin, GLP-1,Glucose Level, VAS for Hunger, VAS for Satiety and Ad Libitum Intake 4 Hours After Breakfast in Obese Women
Gut hormones, such as PYY and ghrelin, are associated with appetite control and obesity. Protein is thought to be the most satieting nutrient and could affect production of several gut hormones.
- Conditions
- PYY, Ghrelin, Appetite, Gut Hormones
- Trial name
- NCT03697486
- Testing
- diet with different composition
- Where
- Indonesia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Obesity
The Effects of Consuming Whey Protein Polydextrose Snacks on Appetite and Energy Intake
Developing functional foods that enhance satiety may be beneficial to individuals to help manage body weight. We have previously shown that consuming a mid-morning liquid preload with increasing proportion of energy derived from…
- Trial name
- NCT01927926
- Testing
- Whey-protein & polydextrose snack, Control snack
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Incretin Action, Obesity
Oxyntomodulin, Mechanisms of Action in Relation to Appetite, Food Intake, Gastric Emptying and Energy Expenditure.
Tiny molecules (hormones) are released from the bowels and other organs to the bloodstream in response to meals in order to orchestrate the metabolism.
- Trial name
- NCT01232244
- Testing
- GLP-1 infusion, Glucagon infusion, Oxyntomodulin infusion
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Obesity
Full4Health: Understanding Food-gut-brain Axis Across the Lifecourse
The primary aim of this work is, to 'relate psychological and behavioural parameters of hunger/satiety and food preference to gut hormones, neural activation and energy metabolism by dietary manipulation, across the human…
- Trial name
- F4H (NCT01597024)
- Testing
- Breakfast Study, fMRI Study
- Where
- 3 sites in Greece, Netherlands and 1 more
- Volunteers
- 718 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Obesity, Diabetes Mellitus, Type 2
Dairy and Non-Dairy Alternatives Comparative on Metabolic Outcomes
The purpose of this study is to compare the acute effects of a single serving of dairy and non-dairy alternatives on post-treatment and post-meal glycemia, appetite, plasma amino acid concentrations, and gastrointestinal hormones…
- Trial name
- NCT05919667
- Testing
- Dairy and plant-based dairy beverages and solids
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto