Clinical trials: Satiety Hormones
Change of Gastric pH
Influence of a Bitter Compound and Bittermasking Compound on Gastric pH
The purpose of this study is to elucidate whether bitter taste induced by the bitter compound caffeine and the reduction of bitter taste by addition of the bitter masking compound Homoeriodictyol sodium salt (HED) influence…
- Trial name
- NCT02372188
- Testing
- water, caffeine, caffein + homoeriodictyol sodium salt
- Where
- Austria
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Vienna
PYY, Ghrelin
The Effect of Breakfast With Different Macronutrient Composition on PYY, Ghrelin, GLP-1,Glucose Level, VAS for Hunger, VAS for Satiety and Ad Libitum Intake 4 Hours After Breakfast in Obese Women
Gut hormones, such as PYY and ghrelin, are associated with appetite control and obesity. Protein is thought to be the most satieting nutrient and could affect production of several gut hormones.
- Conditions
- PYY, Ghrelin, Appetite, Gut Hormones
- Trial name
- NCT03697486
- Testing
- diet with different composition
- Where
- Indonesia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Appetite, Dietary Intake
Short and Long-Term Effects of Prebiotic, Probiotic and Synbiotic on Appetite and Dietary Intake
Prebiotics and probiotics are thought to play a role in appetite control and body weight regulation; but little is known about this topic.
- Conditions
- Appetite, Dietary Intake, Body Weight
- Trial name
- NCT04212546
- Testing
- Synbiotic test drink, Control drink
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Endocrine System Diseases
Effect of a Test Meal on Satiation Hormones in Obese and Normal Weight Adolescents
The objective of this study is to examine ghrelin, amylin, glucagon and glucagon-like peptide (GLP)-1 responses to a test meal in lean and obese individuals.
- Trial name
- NCT02020395
- Testing
- test meal (500 kcal)
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Obesity, Overweight
Protected Pea Protein Extract and Satiety Hormone Release
The increasing prevalence of overweight and obesity among the population contributes to increased incidences of chronic metabolic diseases.
- Trial name
- NCT01877057
- Testing
- Saturn
- Where
- Netherlands
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Satiety, Glycemic Index
Incorporating Avocados in Meals
The purpose of this study is to examine the effect of incorporating avocados in meals on post-ingestion glycemic index, insulin response, sensations of satiety and on appetite-related gastrointestinal peptide and hormone release.
- Conditions
- Satiety, Glycemic Index, Insulin, Gastrointestinal Peptides and Hormones
- Trial name
- NCT01271829
- Testing
- Avocado supplement, Avocado included
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Energy Intake, Gastrointestinal Hormones
Effects of Oral Xylitol on Subsequent Energy Intake
The aim of this project is to investigate the effect of xylitol (given as pre-load), compared to sucrose, Ace-K, and water on energy intake during a subsequent ad libitum test meal in healthy participants.
- Conditions
- Energy Intake, Gastrointestinal Hormones, Glycemic Control, Appetite
- Trial name
- NCT05671965
- Testing
- Xylitol, Sucrose, Acesulfame Potassium
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Insulin Resistance, Satiety
Gut Hormone Response After Paleolithic-type Meals
The effects of two palaeolithic-type meals will be assessed with respect to a panel of gut hormones, satiety, blood glucose and insulin levels as compared to a meal constructed along the lines of the world Health Organisation…
- Trial name
- FooA2 (NCT01999504)
- Testing
- PAL-2, TFH-1, Reference
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Obesity
Energy Balance Weight Regulation Study
The purpose of this study is to test the hypothesis that a low-carbohydrate diet will impact hormones and other factors that regulate appetite and energy balance, and result in lower energy intake and greater weight loss, than a…
- Trial name
- BALANCE (NCT00619008)
- Testing
- Ad libitum low carbohydrate diet, Ad libitum High Complex Carbohydrate Diet, Energy-restricted high complex carbohydrate diet
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Metabolic Syndrome
The Effect of Oat Processing on Gastric Emptying and Satiety Induced After Consuming Porridge
This crossover study is designed to compare the gastric layering and rates of emptying and by inference rates of digestion of two different porridge meals prepared from either finely milled or flaked oats.
- Trial name
- Oatmet (NCT02655367)
- Testing
- Flaked oats, Milled oats
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Appetite
Cereal-based Products Fortified With Legumes and Effects on Glycemic Control and Appetite Regulation
Legumes are rich source of proteins and dietary fibers which are associated with satiety and amelioration of postprandial glycemic response.
- Trial name
- NCT03974165
- Testing
- Cereal-legume product 1, Cereal-legume product 2, Cereal product
- Where
- Greece
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Healthy Male Subjects
Properties of Dietary Fibre and Energy Intake
Dietary fibers likely have a role in body weight management. They may increase satiety and, as a consequence, reduce energy intake during the next meal.
- Trial name
- ProVe (NCT01257295)
- Testing
- control: no fiber addition, breakfast with low viscous, low gelling pectin, high viscous, low gelling pectin
- Where
- Netherlands
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Esophageal Neoplasms, Stomach Neoplasms
Food Intake and Gut Hormones in Patients Who Have Undergone Upper Gastrointestinal Surgery for Cancer
Improvements to treatment strategies for patients upper gastrointestinal cancers have produced an increasing population of people who remain free from disease recurrence in the long term.
- Conditions
- Esophageal Neoplasms, Stomach Neoplasms, Weight Loss, Malnutrition
- Trial name
- NCT02385617
- Testing
- Octreotide
- Where
- 2 sites in Ireland, Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Healthy Volunteers
Evaluation of Glycemic Index, Glycemic Load and Insulinemic Index of Spanish Breads
The present study was carried out to determine the glycaemic index (GI), glycaemic load (GL), insulinaemic index (InI), appetite ratings and postprandial plasma concentrations of gastrointestinal hormones related to the control…
- Trial name
- BREADGI (NCT02297074)
- Testing
- Ordinary white bread, Precooked-Frozen White Bread, Candeal-flour White Bread
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Organización Interprofesional Agroalimentaria de Cereales Panificables y Derivados
Dyslipidemias
Evaluation of Common Bean Baked Snack Consumption on Blood Lipids in Overweight People With Altered Blood Lipid Levels
Introduction: The Mexican population consumes vegetables and snacks with the same frequency. Besides, most of the snacks available on the market contain high fat, sodium and calorie, and low protein levels.
- Trial name
- NCT05028699
- Testing
- Snack
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Centro Universitario de Ciencias de la Salud, Mexico
Appetite Regulation
The Effects of Rye Crisp Bread on Appetite and Metabolic Function
The aim of this study is to contribute to a better understanding of how dietary fibre in rye affects appetite and metabolic processes.
- Trial name
- S2RBAM (NCT02011217)
- Testing
- Rye crisp bread A, Rye crisp bread B, Wheat crisp bread C
- Where
- Sweden
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swedish University of Agricultural Sciences
Overweight and Obesity
Evaluation of Libramed in Obesity Treatment
Randomized, double-blind, placebo-controlled study aimed at evaluating the effects of a 3-months treatment with Policaptil Gel Retard on postprandial incretin hormones release and satiety in obese women
- Trial name
- ELOT (NCT03537235)
- Testing
- Libramed
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Aboca Spa Societa' Agricola
Feeding Behavior
Effect of Resistant Wheat Starch on Subjective Appetite and Food Intake in Healthy Adults
A randomized, single-blind, cross-over study was conducted to determine the effect of replacing standard wheat flour (SWF) with resistant wheat starch (RWS) on markers of appetite and food intake in healthy adults.
- Trial name
- NCT02689791
- Testing
- Resistant Starch Type 4
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Satiety
Satiety Response After Mixed Fiber Doses
People who eat more dietary fiber have a lower body weight than people who eat less fiber. Potential mechanisms include greater feelings of satiety, reductions in food intake, changes in blood glucose, insulin, or gut hormones.
- Trial name
- NCT00889993
- Testing
- Mixed Fiber Supplement
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity, Hormone Responses
Effect of Gastric Bypass Surgery on Brain Responses
After obesity surgery gastric bypass (GBP) patients usually lose more than 50% of its former preponderance in relative short time (~ 2 years).
- Conditions
- Obesity, Hormone Responses, Cognitive Health
- Trial name
- NCT01815216
- Testing
- Bariatric surgery, Brain activity in resting state, Memory performance
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Uppsala University