Clinical trials: Scar, open to volunteers
Forehead; Wound
Topical CBD Scar Outcomes Study
The purpose of this study is to find out what effects (good and bad) that cannabidiol (CBD) has on scar healing and appearance in patients who have undergone paramedian forehead flap reconstruction.
- Trial name
- TOPSCAR (NCT05650697)
- Testing
- Group 1 cannabidiol (CBD) with silicone ointment, Group 2 silicone patch
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Oklahoma
Microbiome
Effect of a Probiotic or Postbiotic on Gut Microbiome During Antibiotic Treatment
This study assesses the effects of a probiotic or postbiotic on gut microbiome during antibiotic treatment.
- Trial name
- POTATO-2 (NCT07594860)
- Testing
- Probiotic, Postbiotic
- Where
- Greece
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Colorectal Polyps
White Light, TXI, NBI and Computer-Aided Detection for Recurrence at Post-EMR Scars (PRINCESS)
Large colorectal polyps removed piece by piece (piecemeal endoscopic mucosal resection) can recur at the resection scar. Detecting this residual or recurrent tissue at surveillance colonoscopy is essential, because it can then be…
- Trial name
- PRINCESS (NCT07874152)
- Testing
- High-definition white light endoscopy (WLE), Texture and color enhancement imaging (TXI), Narrow-band imaging (NBI)
- Where
- 2 sites in Spain
- Volunteers
- 206 people
- Sponsor
- University Hospital Virgen de las Nieves
Surgical Wound Healing, Botulinum Toxin, Type A
Botulinum Toxin Type A for Wound Healing After Laparoscopic Colectomy
This study aims to evaluate the efficacy and safety of botulinum toxin type A (BTX-A) injection as an adjunct to surgical wound healing in patients undergoing laparoscopic colectomy.
- Trial name
- NCT07795463
- Testing
- Botulinum toxin type A (Botox®, Allergan)
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Pham Ngoc Thach University of Medicine
Scarring
Undermining Apices in Surgical Wounds
When patients have surgery on the neck, trunk, arms, or legs, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring.
- Trial name
- NCT05758181
- Testing
- Apical Undermining
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Keloids, Keloids Scars
A Prospective Observational Clinical Study on Exploring the Value of Surgical Excision Combined With 32P Application in the Treatment of Keloids and the Factors Affecting the Prognosis of Combined Therapy
Keloids are non-cancerous (benign) growths on the skin. They form after an injury, when the skin makes too much connective tissue that thickens and hardens. These keloids cause big problems for people.
- Trial name
- NCT07413497
- Volunteers
- 401 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cesarean Section Complications, Uterine Bleeding
Platelet Rich Plasma for Uterine Scar
When vessel wall injury occurs, platelets become activated, releasing more than 30 bioactive proteins, many of which have a fundamental role in hemostasis, inflammation and ultimate wound healing.
- Conditions
- Cesarean Section Complications, Uterine Bleeding, Pelvic Pain, Menstrual Irregularity
- Trial name
- AA-PRP (NCT05224726)
- Testing
- Platelet Rich Plasma
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Cesarean Scar Pregnancy
Comparison Between Surgical Excision and Ultrasound Guided Evacuation in Management of Cesarean Section Scar Pregnancy.
patients diagnosed with cesarean section scar ectopic pregnancy type II will be divided into two groups, one will undergo surgical excision and the other one will undergo ultrasound-guided evacuation in order to compare safety…
- Trial name
- NCT07166627
- Testing
- surgical excision of cesarean section scar ectopic pregnancy, ultrasound guided evacuation of cesarean section scar ectopic pregnancy
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Sohag University
Dysmenorrhea, Cesarean Section
Abdominopelvic Fascial Release for Post-Cesarean Menstrual Pain and Scar Mobility
The goal of this randomized controlled clinical trial is to determine whether adding abdominopelvic fascial release to a standardized stretching exercise program is more effective than stretching exercises alone in reducing…
- Conditions
- Dysmenorrhea, Cesarean Section, Postoperative Adhesions
- Trial name
- NCT07717983
- Testing
- Abdominopelvic fascial Release
- Volunteers
- 58 people
- Sponsor
- Cairo University
Dyspareunia
Effectiveness of Radiofrequency Combined With Ultrasound for the Treatment of Postpartum Dyspareunia
The objective of this community-based, non-randomized, quasi-experimental study is to assess the effectiveness of BTL EXILIS technology-based on combined radiofrequency and ultrasound-in women of childbearing age from an…
- Trial name
- NCT07504991
- Testing
- Combining radiofrequency and ultrasound. BTL Exilis
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Skin Wound Healing After Cesarean Section, Cesarean Section Scar Healing
Tissue-Engineered Construct Based on Amniotic Membrane and Calcium Alginate for Cesarean Section Wound Healing
This clinical trial aims to evaluate the safety and efficacy of an experimental tissue-engineered construct (TEC) based on amniotic membrane and calcium alginate for promoting epithelialization and improving scar quality in…
- Trial name
- NCT07241013
- Testing
- Tissue-engineered construct based on amniotic membrane and calcium alginate (TEC)
- Where
- Kazakhstan
- Volunteers
- 100 people
- Sponsor
- Asfendiyarov Kazakh National Medical University
Burns
Phase III Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents
This multicentre phase III clinical trial will target adults and adolescents of 12 years and older with severe burns to confirm the efficacy and functionality of denovoSkin™ in achieving wound closure and reducing scarring in…
- Trial name
- NCT06745557
- Testing
- denovoSkin(TM), STSG
- Where
- 19 sites in Belgium, France and 7 more
- Volunteers
- 70 people
- Sponsor
- CUTISS AG
Scar Conditions and Fibrosis of Skin, Scar Quality Assessment and Safety
Scar Remodeling After Burn Injury Using Allogeneic Adipose-derived Stromal Cells
The present project serves to test whether stem cell therapy offers a new treatment option for the scars of burn survivors. In Denmark, 12.000 people seek medical assistance every year for burn injuries leaving thousands of…
- Conditions
- Scar Conditions and Fibrosis of Skin, Scar Quality Assessment and Safety, Scar Tissue
- Trial name
- ScarASC (NCT07635875)
- Testing
- Allogeneic adipose-Derived Mesenchymal Stromal Cells, Cryostor CS10 + Ringers Lactate
- Where
- Denmark
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cesarean Scar Pregnancy
The Treatment Outcomes of Cesarean Scar Pregnancy
A prospective randomized controlled study evaluating the impact of various treatment modalities for cesarean scar pregnancy on treatment outcomes and pregnancy outcomes
- Trial name
- NCT07608094
- Testing
- different surgical treatment
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Caesarean Scar Pregnancy
Surgical Evacuation Versus Methotrexate Injection in Treatment of Caesarean Scar Pregnancy [Clinical Trial ]
The aim of the study is to compare the effectiveness and the complications of Ultrasound guided surgical evacuation versus using combined local and systemic methotrexate injection for management of caesarean scar pregnancy.
- Trial name
- NCT07288307
- Testing
- Surgical evacuation and methotrexate injection
- Volunteers
- 42 people
- Sponsor
- Minia University
Myofascial Release, Deep Friction Massage
Effect of Myofascial Release Versus Deep Friction Massage on Abdominal Recovery and Scar After Cesarean Section
This study was done to compare the effect of myofascial release versus deep friction massage on abdominal recovery and scar after cesarean section.
- Conditions
- Myofascial Release, Deep Friction Massage, Cesarean Section Complications, Scar
- Trial name
- NCT07130747
- Testing
- Myofascial release, Deep friction massage, Routine daily scar care advices
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Burn Scar, Burn Wound
Post-Operative Use of FS2 to Mitigate Scarring in Burn Patients
The goal of this study is to see how an ingredient called kynurenic acid (which we named "FS2") affects scar formation in people with burn injuries that need skin graft surgery.
- Trial name
- NCT06807021
- Testing
- IP1 control cream (Vehicle base), IP2 - 0.5% w/w FS2
- Where
- 2 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Birch BioMed Inc
Corneal Scar
Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars
This study will enroll subjects with recently formed corneal scars that resulted from a corneal insult presenting and diagnosed within the past approximately 30 days and not less than approximately 7 days.
- Trial name
- NCT06257355
- Testing
- CSB-001 Ophthalmic Solution 0.1%
- Where
- 7 sites in United States
- Volunteers
- 20 people
- Sponsor
- Claris Biotherapeutics, Inc.
Cesarean Scar Diverticulum
A Randomized Controlled Study of Uterine Incision Diverticulum Repair vs. no Repair During Second/Third Cesarean Section
The goal of this study is to assess the efficacy and safety of uterine incision diverticulum repair during repeat cesarean section.The main questions it aims to answer are: Can this surgical method improve the symptom of…
- Trial name
- NCT06612957
- Testing
- Repair of uterine cicatricial diverticulum
- Volunteers
- 60 people
- Sponsor
- Shanghai First Maternal and Infant Health Hospital affiliated to Tongji University Medical School
Acne Scars, Ablative Fractional CO₂ Laser Therapy
Comparative Real-world Study on Ablative Fractional CO₂ Laser vs PRP With Microneedling for Acne Scar Treatment.
Road traffic accidents (RTAs) remain a major public health concern worldwide and in Bangladesh, contributing significantly to injury, disability, and premature death.
- Conditions
- Acne Scars, Ablative Fractional CO₂ Laser Therapy, Platelet-rich Plasma (PRP)
- Trial name
- NCT07189923
- Testing
- Ablative Fractional CO₂ Laser, Platelet-Rich Plasma (PRP) With Microneedling
- Where
- Bangladesh
- Volunteers
- 116 people
- Sponsor
- Dr. Sirajul Islam Medical College