Clinical trials: Scar Improvement
Hypertrophic Scar, Scar
Silicone Taping for the Improvement of Abdominal Donor Site Scars
This study will look at silicone tape compared to the current no dressing standard at the investigators institution, to determine if silicone tape provides a significant improvement in post-abdominoplasty scar appearance.
- Trial name
- NCT04506255
- Testing
- Silicone tape
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Nova Scotia Health Authority
Scar Keloid, Hypertrophic Scar
Botulinum Toxins Intralesional Injection for Scar Pain
Botulinum toxins has been approved by the FDA to treat chronic migraine. Botox had been shown to inhibiting the release of inflammatory mediators and peripheral neurotransmitters from sensory nerve to treat neuropathic pain.
- Trial name
- NCT03982862
- Testing
- Triamcinolone, Lidocaine, Botulinum toxin A
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Kaohsiung Medical University
Scar Improvement by Laser
Laser Treatment in Early Wound Healing to Promote Physiological Skin Remodeling
The primary objective of this study is to explore the potential clinical effect of targeting surgical wounds in all three wound healing phases by non ablative fractional laser (NAFL) to reduce scar formation in a randomized…
- Trial name
- NCT03253484
- Testing
- NAFL-treatment
- Volunteers
- 32 people
- Sponsor
- Bispebjerg Hospital
Urinary Tract Infections
Prevention of Renal Failure in Children With Urinary Tract Infections
The aim of the study is to describe the current clinical management of young children with urinary tract infections in Dutch primary care and also to describe the possibilities for improvement and potential cost-efficiency of…
- Trial name
- NCT00316043
- Testing
- Written information for parents, Distance learning package for General Practitioners, Distance learning package for practice assistants
- Where
- Netherlands
- Volunteers
- 124 people
- Sponsor
- Radboud University Medical Center
Scar
Safety and Efficacy of Different Onset Times of Treatment With Pulsed Dye Laser on Improvement of Surgical Scars
The appearance of skin after surgery plays an important role in patient's self confidence and life style. In fact, Keloids and hypertrophic scars are abnormal wound responses appearing in predisposed individuals after surgery.
- Trial name
- NCT00506363
- Testing
- pulsed dye laser therapy
- Where
- Iran
- Volunteers
- 15 people
- Sponsor
- Tehran University of Medical Sciences
Scars, Striae
Feasibility Study: Evaluation of the Treatment of Striae Using Ultherapy® in Combination With Laser Treatment
Up to 20 subjects will be enrolled. Enrolled subjects will receive one of three study treatments in the abdominal region: Ultherapy® only, Ultherapy® and CO2 laser treatment, or CO2 laser treatment only.
- Trial name
- NCT01810484
- Testing
- Ultherapy® treatment only, Ultherapy® treatment and CO2 laser treatment, CO2 Laser treatment only
- Where
- 2 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Scar
Celotres for Improvement in Wound Healing and Resulting Scar Consequences Following Suturing of a Wound
The objective of the study is to actively gather additional information on safety, device performance and possible emergent risks following the use of Celotres in a post-market setting when used to improve wound healing and the…
- Trial name
- PMCS EURO HEAL (NCT01706848)
- Testing
- Celotres, Surgical Closure by Standard of Care
- Where
- 9 sites in Poland, United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Halscion, Inc.
Wrinkle, Pigmentation
Device for Improving Skin Quality and Texture on the Face and Neck
The goal of this clinical trial is to investigate the effect of the BTL-785F device (with BTL-785-4-4 tip on BTL-785-4 applicator) on the improvement of skin quality and texture on the face and neck in healthy adult volunteers.
- Conditions
- Wrinkle, Pigmentation, Skin Laxity, Skin Scarring
- Trial name
- NCT06645366
- Testing
- Treatment with BTL-785F
- Where
- 3 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Scars
Juvista in the Non-surgical Improvement of Existing Scars
Renovo, a Biopharmaceutical company involved in the development of drugs to improve the appearance of scars and enhance wound healing, are proposing to carry out research in improving the appearance of existing scars that are 2-6…
- Trial name
- NCT00821457
- Testing
- Juvista
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Renovo
Cicatrix, Breast Reconstruction
Abdominal Scar Improvement in Microsurgical Breast Reconstruction
Microsurgical breast reconstruction is most commonly performed with free abdominal flaps, which leave a long transverse lower abdominal scar. Due to tension across the incision, these scars frequently widen and hypertrophy.
- Trial name
- NCT05377723
- Testing
- Neodyne Device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Scar
Safety and Efficacy of Different Intervals of Pulsed Dye Laser Sessions on Improvement of Surgical Scars
The appearance of skin after surgery plays an important role in patient's self confidence and life style. In fact, Keloids and hypertrophic scars are abnormal wound responses appearing in predisposed individuals after surgery.
- Trial name
- NCT00506090
- Testing
- pulsed dye laser therapy
- Where
- Iran
- Sponsor
- Tehran University of Medical Sciences
Cesarean Scar Defect
Hysteroscopic "360°" Surgery for Improvement of Symptoms in Cesarean Scar Defects
Patients with symptomatic Cesarean Scar Defect (CSD) who are expected to undergo hysteroscopic surgery will be randomly divided into the traditional hysteroscopic "channelization" treatment group and the hysteroscopic "360 °"…
- Trial name
- NCT06917014
- Testing
- 360°, traditional
- Volunteers
- 88 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Scar Improvement, Cosmetic Outcome
Tape Application Protocol for Enhanced Scars
What is the purpose of this study? The Investigators want to find out whether applying Micropore surgical tape to the medial half of the mastectomy scar for 3 months helps improve its appearance after 12 months, compared to no…
- Trial name
- TAPES (NCT07144046)
- Testing
- Micropore covering of the medial half of the scar
- Volunteers
- 90 people
- Sponsor
- Herlev Hospital
Cicatrix
Improvement in Scar Appearance Following Injection of Avotermin (Juvista) Into Skin Incisions Made in Healthy Men and Women
This is a single-centre, double-blind, Placebo-controlled, randomised trial. Trial subjects received four 1cm incisional wounds on the inner aspect of each upper arm (eight in total), giving four pairs of anatomically matched…
- Trial name
- NCT00629811
- Testing
- Avotermin (Juvista)
- Where
- United Kingdom
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Renovo
Burn Scars
Non Ablative Fractional Laser Treatment of Burn Scars
BACKGROUND: Increasing evidence appears for non-ablative fractional laser (NAFL) to remodel mature burn scars. OBJECTIVES: To investigate long-term clinical and histological appearance of mature burn scars after NAFL-treatment.
- Trial name
- NCT02014298
- Testing
- non-ablative fractional laser, control
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Bispebjerg Hospital
Burn, Hypertrophic Scars
Carbon Dioxide Laser-Assisted Delivery of Triamcinolone With or Without 5-Fluorouracil for Hypertrophic Burn Scars
Burn scars can sometimes heal in a way that causes them to become thick, raised, and stiff. These scars may itch, feel uncomfortable, limit movement, and affect how the skin looks.
- Conditions
- Burn, Hypertrophic Scars, Scar Improvement by Laser, CO2 Laser in Scars
- Trial name
- NCT07660120
- Testing
- Fractional Ablative CO₂ Laser, Triamcinolone Acetonide, Fluorouracil (5-FU)
- Volunteers
- 65 people
- Sponsor
- University of California, Davis
Dyspareunia
Effectiveness of Radiofrequency Combined With Ultrasound for the Treatment of Postpartum Dyspareunia
The objective of this community-based, non-randomized, quasi-experimental study is to assess the effectiveness of BTL EXILIS technology-based on combined radiofrequency and ultrasound-in women of childbearing age from an…
- Trial name
- NCT07504991
- Testing
- Combining radiofrequency and ultrasound. BTL Exilis
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Nevus, Cicatrix
A Trial to Investigate Scar Improvement Efficacy of RN1001 (Avotermin) After Head and Neck Naevi Excision
This trial will investigate whether four doses of RN1001 (20ng, 50ng, 100ng and 200ng) are efficacious in preventing or reducing the resultant scar, as compared to placebo, when applied intradermally to wound margins following…
- Trial name
- NCT00656227
- Testing
- Avotermin
- Where
- United Kingdom
- Volunteers
- 239 people
- Sponsor
- Renovo
Acne Scars - Mixed Atrophic and Hypertrophic
Safety and Efficacy of Sofwave Treatment for Acne Scars Appearance Improvement
Open-label, non-randomized, prospective, multi-center, self-controlled clinical study with masked evaluation.
- Trial name
- NCT05358860
- Testing
- Sofwave
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Scar Improvement
A Trial to Compare the Efficacy of Two Formulations of Avotermin Against Placebo
RN1006 has been developed as a stabilized formulation of avotermin which, when dosed once in pre-clinical studies in animals, has shown comparable scar improvement efficacy to the standard twice-dosed Juvista formulation.
- Trial name
- RN1006 (NCT01029158)
- Testing
- Juvista (Avotermin), RN1006 (Avotermin)
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Renovo