Clinical trials: Scarring
Burn Scar, Itch Scarring
Novel Strategies for Reducing Burn Scar Itch
The purpose of the study is to see whether using diphenhydramine (Benadryl), famotidine (Pepcid), and cromolyn sodium will decrease burn scar itch.
- Conditions
- Burn Scar, Itch Scarring, Wound
- Trial name
- NCT06801626
- Testing
- Famotidine and 4% topical cromolyn sodium
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Scarring Alopecia, Androgenetic Alopecia
1470nm Laser for the Treatment of Androgenetic Alopecia and Scarring Alopecia
Single-center, open-label, baseline-controlled, pilot study evaluating the use of a Nonablative 1470 nm laser for the treatment of androgenetic alopecia and scarring alopecia.
- Trial name
- NCT05460611
- Testing
- Sciton HALO 1470nm Non-ablative laser
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Atrophic Acne Scarring
Poly-L-Lactic Acid in Atrophic Acne Scars
Background: Management of atrophic acne scars remains challenging due to their heterogeneous morphology and suboptimal response to conventional therapies.
- Trial name
- NCT07523217
- Testing
- injectable PLLA, PLLA threads
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Facial Scarring, Facial Trauma
Tools for Return of Facial Function
This study will evaluate novel intraoral (inside-the-mouth) splints designed to gently stretch facial tissues that have become tight or scarred following facial trauma, including burn injuries and gunshot wounds.
- Conditions
- Facial Scarring, Facial Trauma, Burn, Orofacial Contracture
- Trial name
- NCT07825844
- Testing
- Intraoral Stretching Splints
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Scarring
Aesthetic Outcome of Tie-over Bolster Application in Surgical Wounds
When patients have surgery on the head and face, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring.
- Trial name
- NCT05758168
- Testing
- Addition of Tie-Over Bolster Dressing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Scarring
Pinch Grafting Versus Second Intention Wound Healing for Mohs Micrographic Surgery Defects on the Scalp
Oftentimes, following surgery on the scalp, wounds are left to heal by themselves. This is called "second intention." Open wounds left to heal on the scalp often take 8 weeks or more to completely heal.
- Trial name
- NCT06287866
- Testing
- Pinch Graft
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of California, Davis
Skin Scarring, Skin Elasticity
Skin Elasticity Measurements of the Face and Surgical Scars Stratified by Age and Skin Type
The primary objective of Part A is to compare the change in elasticity measurements at baseline and at 3 months between subjects who have had a resurfacing or tightening procedure and those who have not.
- Trial name
- NCT01688063
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Facial Scarring
The Application of Intralesional 5-fluorouracil for the Management of Hypertrophic Facial Scars in the Periocular Region Resulting From Trauma and Surgical Procedures in Individuals Aged Over 18 Years
To determine the effectiveness of intralesional 5-fluorouracil in objectively reversing hypertrophic scars in the periocular region resulting from trauma or cosmetic surgery.
- Trial name
- AI5FMHFSPRFSOE (NCT07397520)
- Testing
- Intralesional administration of 5-fluorouracil
- Where
- Mexico
- Volunteers
- 7 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Acne Scars, Acne Scars - Atrophic
Safety and Efficacy Evaluation of the Radiofrequency Therapeutic Device for the Treatment of Atrophic Acne Scars
The objective of this clinical trial is to evaluate the safety and effectiveness of a radiofrequency treatment device for the treatment of atrophic acne scars.
- Conditions
- Acne Scars, Acne Scars - Atrophic, Acne Scar, Acne Scarring
- Trial name
- NCT07620769
- Testing
- Investigational Device with the function deactivated, Investigational Device with the function activated, Control Device
- Where
- 4 sites in China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Androgenetic Alopecia, Alopecia
THERAVEX® REGENERA Tissue Care Plus for Hair Regeneration and Follicular Microenvironment Modulation
To evaluate the safety and clinical performance of THERAVEX® REGENERA Tissue Care Plus as an adjunctive regenerative support therapy in patients undergoing hair restoration procedures and regenerative scalp treatment protocols.
- Conditions
- Androgenetic Alopecia, Alopecia, Hair Loss, Non-scarring Alopecia
- Trial name
- NCT07615608
- Testing
- Standard Hair Restoration Care
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Biointelligent Technology Systems SL
Corneal Scarring Fibrosis
Losartan for Corneal Fibrosis
This is a prospective, randomized, double-blinded, controlled clinical trial designed to evaluate the efficacy and safety of topical losartan in improving visual acuity, contrast sensitivity and reducing corneal densitometry…
- Trial name
- NCT07449000
- Testing
- Topical losartan
- Where
- Mexico
- Volunteers
- 46 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Facial Scarring
Comparative Study for Facial Scar Remodeling Using Fractional Carbon Dioxide Laser Combined With PDRN Versus Fractional CO₂ Laser
Facial scars are frequently deemed unpleasant and can profoundly impact a patient's psychological health. This study compares the effectiveness, safety, and capacity to speed up scar healing in the maxillofacial region between…
- Trial name
- PDRN CO2 LASER (NCT07472192)
- Testing
- Polydeoxyribonucleotide, Fractional CO2 laser assisted PDT
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Misr University for Science and Technology
Recurrent Pterygium, Conjunctival Scarring
Digital Colorimetric Scale for Recurrent Pterygium Scar Assessment
This observational study aims to evaluate and validate a digital colorimetric scale for the objective assessment of conjunctival scarring in patients with recurrent pterygium.
- Trial name
- DCS-PTER (NCT07458126)
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Scarring Due to Treatment
Silicone Gel for Postsurgical Scars of the Eyelid
To determine whether silicone gel is effective at preventing or minimizing scar formation after eyelid surgery.
- Trial name
- NCT03601247
- Testing
- silicone gel
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Scarring
Undermining Apices in Surgical Wounds
When patients have surgery on the neck, trunk, arms, or legs, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring.
- Trial name
- NCT05758181
- Testing
- Apical Undermining
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Scarring
Aesthetic Outcome of Intra-dermal Versus Transcutaneous Purse-string Closure
The purpose of this study is to determine whether intra-dermal versus transcutaneous purse-string closures have similar scar cosmesis and post-operative complications.
- Trial name
- NCT06448481
- Testing
- Intra-dermal purse-string closure, Transcutaneous purse-string closure
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of California, Davis
Hidradenitis Suppurativa, Scarring
Efficacy and Tolerability of a Fractional Ablative Erbium Laser for Axillary Scarring for Hidradenitis Suppurativa Patients
Single center, open-label, baseline-controlled study evaluating the use of a Sciton fractionated ablative laser in the treatment of Hidradenitis Suppurativa (HS) scarring.
- Trial name
- NCT05470322
- Testing
- Er: YAG laser
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Scarring Alopecia
Non-Ablative Laser to Treat Scarring Alopecia With Hair Follicle Gene Expression Analysis
The goal of this clinical trial is to evaluate the effectiveness of a non-ablative 1470 nm laser in treating scarring alopecia in adults.
- Trial name
- NCT06946550
- Testing
- 1470nm non-ablative fractional laser
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Scarring
Outcomes of Running Locking Suture vs Standard Running Suture in Surgical Wounds
When patients have surgery on the head and face, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring.
- Trial name
- NCT06288009
- Testing
- Running locking suture, Standard running suture
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Burn Scar, Hypertrophic Scarring
Remimazolam vs Propofol in Laser Burn Cases
This randomized, single-blind, crossover study compares remimazolam and propofol for monitored anesthetic care during fractional ablative CO₂ laser therapy for burn scars.
- Conditions
- Burn Scar, Hypertrophic Scarring, Procedural Sedation
- Trial name
- NCT07213544
- Testing
- Remimazolam besylate, Propofol
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Medical University of South Carolina