Clinical trials: Scarring, open to volunteers
Burn Scar
The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars
The purpose of this study is to determine the effects (good or bad) of pulsed dye laser treatment in burn scar height, texture, redness and pliability in acute burn injury.
- Trial name
- NCT01488240
- Testing
- pulsed dye laser
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- University of Manitoba
Scar Formation
The Effectiveness of Topical Silicone Application Combined With Photoprotection in the Development of Scarring Following Blepharoplasty
Assess the efficacy of utilizing topical silicone with photoprotection (Improscar Stick® 50) on the quality of healing following upper blepharoplasty, employing the Vancouver and POSAS scales (both patient and observer) over a…
- Trial name
- ETSACPDSFP (NCT07387536)
- Testing
- Silicone-based topical formulation with sunscreen (SPF 50) application
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Scar
Microneedling vs Dermabrasion for Early Facial Scar Resurfacing
This study aims to determine whether microneedling or dermabrasion in the early post-operative period is superior in improving the appearance of surgical scars on the face.
- Trial name
- NCT06171386
- Testing
- Microneedling, Dermabrasion
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences
Alpha1-Antitrypsin Deficiency
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein
The main aim of this study is to learn if fazirsiran reduces liver scarring (fibrosis) compared to placebo. Other aims are to learn if fazirsiran slows down the disease worsening in the liver, to get information on how fazirsiran…
- Trial name
- NCT05677971
- Testing
- Fazirsiran Injection
- Where
- 89 sites in United States, Australia and 17 more
- Volunteers
- 160 people
- Sponsor
- Takeda
Corneal Scar
Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars
This study will enroll subjects with recently formed corneal scars that resulted from a corneal insult presenting and diagnosed within the past approximately 30 days and not less than approximately 7 days.
- Trial name
- NCT06257355
- Testing
- CSB-001 Ophthalmic Solution 0.1%
- Where
- 7 sites in United States
- Volunteers
- 20 people
- Sponsor
- Claris Biotherapeutics, Inc.
Scars
Autologous Nanofat Grafting by Injection Versus With Microneedling in Post-burn and Traumatic Atrophic Scars
This study aims to evaluate the efficiency autologous nanofat injection versus autologous nanofat delivered by microneedling in management of post burn atrophic and traumatic scars.
- Trial name
- NCT06566300
- Testing
- injection of autologous nanofat grafting, microneedling with autologus nanofat graft
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Alpha1-Antitrypsin Deficiency
Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)
The liver produces a protein called alpha-1 antitrypsin (AAT). AAT is normally released into the bloodstream. In some people, the liver makes an abnormal version of the AAT protein, called Z-AAT.
- Trial name
- NCT06165341
- Testing
- Fazirsiran Injection
- Where
- 41 sites in United States, Austria and 11 more
- Volunteers
- 50 people
- Sponsor
- Takeda
Metastatic Melanoma
Generation of an Artificial Intelligence Algorithm Based on the Analysis of Melanoma Peri-scar Dermatoheliosis, as a Predictive Factor of Response to Anti-PD-1
In the last decade, the advent of immunotherapies with inhibitors of immune checkpoints, such as anti-PD-1 and anti-CTLA-4, has revolutionized the treatment of advanced or metastatic melanoma.
- Trial name
- HELIOPREDICT (NCT05856565)
- Testing
- Photo
- Where
- 20 sites in France
- Volunteers
- 700 people
- Sponsor
- Nantes University Hospital
Keloid
Genetic Analysis of Keloids
Keloids have a strong genetic component. The goal of this study is to identify genes and regulatory elements on chromosomes that are the cause for keloids or contribute to keloid scarring.
- Trial name
- NCT01619553
- Where
- United States
- Volunteers
- 7,000 people
- Sponsor
- UConn Health
Lipoma
RFA for Superficial Lipomas
Lipomas are non-cancerous growths of fatty tissue that develop under the skin in approximately 1 in 1000 people, though this number may be higher.
- Trial name
- NCT06903208
- Testing
- STARMed VIVA Combo RF System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Columbia University
Scar-related Atrial Tachycardia, Persistent Atrial Fibrillation
A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping Catheter
The purpose of this study is to assess the safety and feasibility of the investigational catheter for mapping the atrial and ventricular regions of the heart.
- Conditions
- Scar-related Atrial Tachycardia, Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Ventricular Tachycardia
- Trial name
- FEATHER (NCT07116525)
- Testing
- Paddle-Shaped, High-Density, Multi-Electrode Mapping Catheter
- Where
- 5 sites in Belgium, France and 1 more
- Volunteers
- 90 people
- Sponsor
- Biosense Webster, Inc.
Tissue Adhesions
Cine-magnetic Resonance Imaging (MRI) Detecting Intra Abdominal Adhesions
Official title: Sensitivity and predictive value of functional cine magnetic resonance imaging (MRI) detecting intra-abdominal adhesions Background: Adhesions are a frequent problem in abdominal surgery.
- Trial name
- NCT00882167
- Testing
- CineMRI
- Where
- 5 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center
Surgical Wound Healing, Botulinum Toxin, Type A
Botulinum Toxin Type A for Wound Healing After Laparoscopic Colectomy
This study aims to evaluate the efficacy and safety of botulinum toxin type A (BTX-A) injection as an adjunct to surgical wound healing in patients undergoing laparoscopic colectomy.
- Trial name
- NCT07795463
- Testing
- Botulinum toxin type A (Botox®, Allergan)
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Pham Ngoc Thach University of Medicine
Keloid
Radiotherapy for Keloids
The purpose of this pilot study is to evaluate the safety and efficacy of radiation therapy (RT) in the treatment of unresected keloids.
- Trial name
- NCT04722263
- Testing
- Radiotherapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Montefiore Medical Center
Postoperative Surgical Scar, Scar
Effect of an Intraoperative Polynucleotide Injection on Scar Quality After Thyroidectomy
The goal of this clinical trial is to learn whether a single polynucleotide injection can improve scar quality after thyroid or parathyroid surgery in adults. It will also assess the safety of the injection.
- Conditions
- Postoperative Surgical Scar, Scar, Scar Formation, Neck Scar
- Trial name
- NCT07791953
- Testing
- Polynucleotide (PN-HPT), Sterile 0.9% Sodium Chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Keloid Scar Following Surgery, Scars, Hypertrophic
Measuring the Volumes of Hypertrophic Scars and Keloids, Two Specific Kind of Scars, Over Different Points in Time in Patients Who Have Undergone Surgery and Evaluate 3D-cameras As a Possible Measuring and Documenting Tool Including Volumetry
Measuring the volumes of hypertrophic scars and keloids, two specific kind of scars, over different points in time in patients who have undergone surgery and evaluate 3D-cameras as a possible measuring and documenting tool…
- Conditions
- Keloid Scar Following Surgery, Scars, Hypertrophic, Scar Keloid
- Trial name
- NCT06806735
- Testing
- 3D-Pictures
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Scarring
Undermining Apices in Surgical Wounds
When patients have surgery on the neck, trunk, arms, or legs, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring.
- Trial name
- NCT05758181
- Testing
- Apical Undermining
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Acute Standardized Cutaneous Wounds (Punch-biopsy Wounds)
Topical GHK-Cu Gel for Acute Skin Wound Healing
This study will evaluate whether a topical gel containing GHK-Cu (a copper(II)-peptide complex) can safely speed up healing of small, standardized skin wounds in healthy adults compared with a matching vehicle gel.
- Trial name
- CuHeal (NCT07437586)
- Testing
- GHK-Cu Gel (Copper(II)-peptide complex)
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hudson Biotech
Acne Scars
A Study to Assess the Safety and Effectiveness of ELAPR002f Injectable Gel in Adult Participants With Atrophic Acne Scars
Atrophic acne scars are flat, indented or with an inverted center scars that develop at the endpoint of the normal healing process for acne.
- Trial name
- NCT07207369
- Testing
- ELAPR002f Injectable Gel, Saline Control
- Where
- 10 sites in United States
- Volunteers
- 395 people
- Sponsor
- AbbVie
Dysmenorrhea, Cesarean Section
Abdominopelvic Fascial Release for Post-Cesarean Menstrual Pain and Scar Mobility
The goal of this randomized controlled clinical trial is to determine whether adding abdominopelvic fascial release to a standardized stretching exercise program is more effective than stretching exercises alone in reducing…
- Conditions
- Dysmenorrhea, Cesarean Section, Postoperative Adhesions
- Trial name
- NCT07717983
- Testing
- Abdominopelvic fascial Release
- Volunteers
- 58 people
- Sponsor
- Cairo University