Clinical trials: Scars
Acne Scars
Comparison of 1,550-nm Laser and Fractional Radiofrequency Microneedle for the Treatment of Acne Scars in Ethnic Skin
The primary objective of this randomized, split-face, controlled study is to compare the efficacy and safety of a erbium-doped 1,550-nm non-ablative fractional laser and a bipolar fractional radiofrequency microneedle device for…
- Trial name
- NCT03380845
- Testing
- Fraxel Restore, Fractora
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hypertrophic Scars
Gene Expression During Surgical Scar Remodeling by Fractional Photothermolysis
This project aims to understand the molecular biology underlying the improvement of surgical scars treated by ablative fractional photothermolysis (FP).
- Trial name
- NCT01858038
- Testing
- Fraxel Repair - Fractional Laser treatment
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Burns, Scars
The Technique of Skin Stretching for Acute Burn Treatment and Scar Reconstruction
Objective: A randomized controlled trial is performed to evaluate the clinical effectiveness of the skin stretching technique for two categories: 1.
- Trial name
- NCT00609908
- Testing
- Split skin graft, skin stretching device, serial excision
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Association of Dutch Burn Centres
Atrophic Acne Scar
Straberi Microneedling For Atrophic Acne
This pilot study will expand knowledge and application needling using the Straberi microneedling device for the improvement of Atrophic Acne Scarring
- Trial name
- SAA (NCT04740268)
- Testing
- Straberi
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universal Skincare Institute
Fibrosis, Scarring
High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin
The goal of this study is to establish the safety of high fluence LED-RL from 160 J/cm2 up to 640 J/cm2 in healthy subjects. The hypothesis is that high fluence LED-RL phototherapy is safe in human skin.
- Conditions
- Fibrosis, Scarring, Scar, Wounds
- Trial name
- NCT02630303
- Testing
- LED-RL Phototherapy, Mock Therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jared Jagdeo, MD, MS
Acne Scar
TheTreatment of Acne Scar Using UltraPulse CO2 Laser
Purpose of the study is to assess the effect and evaluate topographic volume changes of UltraPulse at treating boxcar scars with different energy and the effect of UltraPulse at treating icepick scars.
- Trial name
- NCT04648995
- Testing
- High energy (UltraPulse), Low energy (UltraPulse)
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Haute Beauté Skin & Vein Clinic
Acne Atrophica
Monopolar Radiofrequency Versus Pulsed Dye Laser for Treatment of Acne Scars
Background: The acne scar is a common disorder characterized by skin eruption or abnormalities on face, chest, and/or back in the adolescence which affect the cosmetic appearance.
- Trial name
- MRFPDL (NCT04461366)
- Testing
- Monopolar radiofrequency, Pulsed dye laser
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Suture, Complication, Wound
Split Scar Study to Assess Cosmetic Outcome From Differing Suture Spacing
The investigators wish to determine how suture spacing (5 mm vs. 10 mm) affects cosmetic outcome and development of "train tracking" in wounds.
- Conditions
- Suture, Complication, Wound, Wound Complication, Wound Dehiscence
- Trial name
- SFD (NCT03284983)
- Testing
- Suture spacing for wound closure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Silver Falls Dermatology
Scarring Alopecia
Non-Ablative Laser to Treat Scarring Alopecia With Hair Follicle Gene Expression Analysis
The goal of this clinical trial is to evaluate the effectiveness of a non-ablative 1470 nm laser in treating scarring alopecia in adults.
- Trial name
- NCT06946550
- Testing
- 1470nm non-ablative fractional laser
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Skin Diseases, Hypertrophic Scar
Piezoelectric Drived Microneedling in Treating Refractory Skin Diseases
Piezoelectric drived microneedling treats refractory skin disorders using hollow microneedles assisted by ultrasound. Mechanically, the injection of medicine by hollow microneedling could makes the distribution of medicine more…
- Conditions
- Skin Diseases, Hypertrophic Scar, Keloid, Plantar Wart
- Trial name
- NCT05488860
- Testing
- Triamcinolone acetonide(scar)/5-ALA(others), Piezoelectric drived microneedling, 5-ALA (a photosensitizer for photodynamic therapy).
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Keloid
Implantation of Mesenchymal Stem Cell, Conditioned Medium, or Triamcinolone Acetonide for Keloid
The clinical trial will be carried out at the Gatot Soebroto Army Central Hospital, Jakarta and planned from June 2020 to December 2020.
- Trial name
- Keloid (NCT04326959)
- Testing
- Umbilical Cord-Mesenchymal Stem Cells and Conditioned Medium, Conditioned Medium, Triamcinolone Acetonide
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- PT. Prodia Stem Cell Indonesia
Chronic Skin Ulcer, Diabetic Foot
Plasma and Scarring of Diabetic Ulcers
Diabetic foot is defined by World Health Organization as a syndrome in which the presence of neuropathy, ischemia and infection cause tissue damage or ulcers from minor trauma.
- Conditions
- Chronic Skin Ulcer, Diabetic Foot, Plasma Protein; Transport Protein
- Trial name
- NCT04145154
- Testing
- Application of platelet rich plasma in chronic wounds of diabetic origin
- Where
- Mexico
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad de Guanajuato
Cesarean Section Complications, Cesarean Wound Disruption
Cesarean Scar Defect Formation After First Cesarean Section.
This study is a prospective observational study which will monitor how cesarean section in the first pregnancy will develop a cesarean scar defect.
- Conditions
- Cesarean Section Complications, Cesarean Wound Disruption, Cesarean Wound; Dehiscence
- Trial name
- NCT03966001
- Testing
- Transvaginal sonography at six months after cesarean section, Transvaginal sonography at twelve months after cesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Uludag University
Vitiligo, Depigmented Scars
Comparative Study Using Dermabrasion vs CO2 Laser & Collagen Dressing vs Vaseline Gauze in MKTP
The purpose of this study is to: 1. Compare two different techniques in the melanocyte keratinocyte transplant procedure: Use of carbon dioxide laser versus use of dermabrasion 2.
- Conditions
- Vitiligo, Depigmented Scars, Depigmentation
- Trial name
- MKTP (NCT02038257)
- Testing
- MKTP (melanocyte keratinocyte transplant procedure), Collagen Dressing, Vaseline Impregnated Gauze
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Cicatrix
Anti-Scarring Efficacy and Safety of Intradermal Juvista (Avotermin) in Healthy Males
This study was undertaken to investigate safety and scar-improvement activity of different applications of Juvista (avotermin), administered to surgical incisions made to the skin of a healthy population of male volunteers aged…
- Trial name
- NCT00594581
- Where
- United Kingdom
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Renovo
Hypertrophic Scars
Treatment of Hypertrophic Scars Using Fractional Laser and Fractional Laser-assisted Topical Corticosteroid Delivery
The objective of this study is to evaluate the efficacy and safety of using ablative fractional laser- assisted topical corticosteroid delivery for the treatment of hypertrophic scar.
- Trial name
- NCT02487212
- Testing
- 0.05% Clobetasol propionate, Petrolatum gel, Fractional Erbium:Yag (2,940-nm) laser
- Where
- Thailand
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Uterine Scar
Assessment of Single and Double Layer Suturation of Lower Segment Uterine Incision by USG After C/S
After 6 months of cesarean delivery, the investigators will compare uterine incision scar defects of single and double layer suturation of uterine incision by transvaginal ultrasonography.
- Trial name
- NCT03676907
- Testing
- double layer suturation technique
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gazi University
Cicatrix, Carbon Dioxide Laser
Interventional Study to Evaluate the Appearance of Surgical Scars After Laser Therapy
This study evaluates the effect of a fractionated carbon dioxide laser on surgical scars of the face and neck over 12 months. Anyone with a surgical scar on the face and neck who has not had laser therapy may be eligible to…
- Trial name
- NCT02985151
- Testing
- Syneron-Candela CO2RE Laser
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Skin Graft Scar
Surgical Outcomes of Simple Interrupted Versus Running Epidermal Sutures in Full-thickness Skin Graft Placement
The study hypothesis is that the use of running epidermal sutures in full-thickness skin graft (FTSG) placement for patients undergoing dermatologic surgery (Mohs micrographic surgery or excision) is non-inferior to the use of…
- Trial name
- NCT06233812
- Testing
- Simple interrupted suturing technique, Running suturing technique
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Wound Healing
Efficacy of Early Postoperative ON101 Application for Lower-extremity Fracture Incisions: a Prospective Evaluator-blinded Controlled Study of Scar Quality and Digital-clinical Concordance
Background: Postoperative scars after lower-extremity fracture fixation endure high tension, where excessive scarring can restrict periarticular mobility.
- Trial name
- ON101 Efficacy (NCT07854470)
- Testing
- ON101
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- LIN Kai-Cheng