Clinical trials: Schizophenia Disorder, active
Anxiety, Depression - Major Depressive Disorder
Profiling Vulnerability and Resilience for Mental Illness Following Viral Infections: Translating Epidemiology to Deep-phenotyping.
The study protocol was submitted to ERA-NET NEURON for funding on 28/06/2023. Description of the Israeli responsibilities was extracted from the full submitted research protocol. The protocol includes two studies (CHS1 and CHS2).
- Conditions
- Anxiety, Depression - Major Depressive Disorder, Bipolar, Schizophenia Disorder
- Trial name
- Viral-MI (NCT07453420)
- Where
- Israel
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Schizophenia Disorder, Interventional Study
Interventional Programs' Impact on Patients' Quality of Life and Functioning
The objective of the study is to investigate the effect of interventional program in improving the quality of life for individuals with chronic schizophrenia The design of the study will be an interventional study - Randomized…
- Trial name
- NCT06715553
- Testing
- BALANCE Program (Body, Art, Learning, Activities, Nutrition, Creativity, and Education)
- Where
- Lebanon
- Volunteers
- 86 people
- Sponsor
- Psychiatric Hospital of the Cross
Schizophenia Disorder
Biomarkers to Enhance Early Schizophrenia Treatment
This study is recruiting participants who are experiencing a first episode of psychosis and who have certain genetic factors that may make them respond better to certain medications that are used to treat people with psychosis.
- Trial name
- BEEST (NCT06969755)
- Testing
- aripiprazole, risperidone, clozapine
- Where
- 5 sites in United States, Canada
- Volunteers
- 180 people
- Sponsor
- Northwell Health
Schizophenia Disorder
A Remote Life Balance Training Program for People With Schizophrenia
People living with schizophrenia often experience significant disruptions to their ability to maintain a balanced lifestyle and perform daily activities.
- Trial name
- NCT07131137
- Testing
- The Life Balance Training Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people
- Sponsor
- Bezmialem Vakif University
Major Depressive Disorder (MDD), Schizophenia Disorder
Prospective Observational Study of the Relationship Between Sociodemographic Factors, Blood-based Biomarkers and Psychiatric Symptoms in Neurodegenerative Diseases and Mental Disorders
This is a prospective observational study to identify sociodemographic factors that predict mental health outcomes in the European population and provide evidence linking common, modifiable sociodemographic risk factors for…
- Conditions
- Major Depressive Disorder (MDD), Schizophenia Disorder, Bipolar 1 Disorder, Alzheimer Disease
- Trial name
- Synapsing-SD (NCT07239843)
- Where
- Spain
- Volunteers
- 1,310 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Schizophenia Disorder, Bipolar Disorder (BD)
Effects of Schizophrenia and Bipolar Disorder on Exercise Capacity, Pulmonary Function, and Quality of Life
This observational study aims to evaluate exercise capacity, pulmonary function, respiratory muscle strength, and quality of life in individuals diagnosed with schizophrenia and bipolar disorder.
- Trial name
- NCT07306468
- Testing
- Pulmonary Function Test, Respiratory Muscle Strength Evaluation, Quality of Life Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Depression - Major Depressive Disorder, Schizophenia Disorder
A Novel Blood Test as a Biomarker in Mental Health
This longitudinal, observational study aims to assess whether the characteristics of a novel blood peripheral biomarker can serve as indicators for depression and schizophrenia in patients at the Royal Columbian Hospital…
- Conditions
- Depression - Major Depressive Disorder, Schizophenia Disorder, Psychosis, Mania (Neurotic)
- Trial name
- LEADING-MH (NCT06856161)
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Fraser Health
Nurses, Schizophenia Disorder
The Effectiveness of Combining AR/VR Technology in Virtual Clinical Auditory Hallucinations on the Comprehensive Auditory Hallucination Nursing Competency of Psychiatric Nurses
This study aims to develop and evaluate a Virtual Reality (VR) Auditory Hallucination Program to enhance psychiatric nurses' comprehensive care competence in managing auditory hallucinations among patients with schizophrenia.
- Conditions
- Nurses, Schizophenia Disorder, Hallucinations, Auditory
- Trial name
- NCT06938997
- Testing
- Virtual clinical auditory hallucination solution combining AR/VR technology, Auditory Hallucination Care Video
- Where
- 4 sites in Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Schizophenia Disorder, Severe Mental Illness
Effect of Occupational Therapy on Psychosocial Parameters and Functioning in Individuals With Severe Mental Illness
Severe mental illness (SMI), including schizophrenia spectrum disorders and bipolar disorder, is associated with significant impairments in psychosocial functioning, daily life participation, self-efficacy, and social…
- Conditions
- Schizophenia Disorder, Severe Mental Illness, Bipolar Disorder, Nonorganic Psychosis
- Trial name
- OT-SMI (NCT07879118)
- Testing
- Occupational Therapy Group Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
Schizophenia Disorder, Schizoaffective Disorder
Exercise and Olanzapine-samidorphan
This is a single site trial in 30 patients with schizophrenia, schizoaffective, or bipolar I/II/NOS disorder in which all participants will receive eight weeks of olanzapine and samidorphan (Olz/Sam) plus four weeks of aerobic…
- Conditions
- Schizophenia Disorder, Schizoaffective Disorder, Bipolar Disorder I or II, Bipolar Disorder NOS
- Trial name
- NCT06740890
- Testing
- Olanzapine-samidorphan + exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- New York State Psychiatric Institute
Depression, Bipolar Affective Disorder
Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study
The project proposes to develop a digital product based on cognitive behavioral therapy for the assisted treatment of depression.
- Conditions
- Depression, Bipolar Affective Disorder, Schizophenia Disorder, Psychiatric &Amp;or Mood Disorder
- Trial name
- NCT06831435
- Testing
- a digital product based on CBT
- Where
- China
- Volunteers
- 325 people
- Sponsor
- Peking University
Schizophenia Disorder
Evaluating Pharmacogenomics-Based Pharmacotherapy in Real-World Settings for Schizophrenia
An 8-week, rater-blinded, real-world observational study to investigate the benefits of pharmacogenetics-based pharmacotherapy in patients suffering from schizophrenia.
- Trial name
- NCT06700967
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Shanghai Mental Health Center
Schizophenia Disorder
CRacking the HEterogeneity of Social Outcome Through Neuropsychophysiological Profiles
CRHESO aims at overcoming the considerable burden of mental disorders, which affects both psychosocial well-being and societal welfare, through a multidisciplinary and integrated approach to explore and remediate dimensions…
- Trial name
- CRHESO (NCT06869616)
- Testing
- Cognitive Remediation
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Alzheimer Disease, Dementia With Lewy Bodies (DLB)
Retrospective Observational Study of Blood-based Biomarkers in the Diagnosis and Monitoring of Patients With a Neurodegenerative Disease or Mental Disorder
This is a retrospective observational study to evaluate the clinical utility of blood-based biomarkers in the diagnosis and management of patients with a neurodegenerative disease (ND) or mental disorder (MD).
- Conditions
- Alzheimer Disease, Dementia With Lewy Bodies (DLB), Frontotemporal Dementia (FTD), Major Depressive Disorder (MDD)
- Trial name
- Synapsing-BK (NCT07314190)
- Where
- Spain
- Volunteers
- 1,799 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Schizo-affective Disorder, Non Organic Psychosis
Motivational Intervention for Patients With Schizophrenia
The goal of this clinical trial is to learn if a group therapy called the Positive Emotions Program for Schizophrenia (PEPS) can reduce apathy in adults aged 18 to 60 who have schizophrenia or a related psychotic disorder.
- Conditions
- Schizo-affective Disorder, Non Organic Psychosis, Schizophenia Disorder
- Trial name
- NCT07853079
- Testing
- Positive Emotion Program for Schizophrenia (PEPS), a psychotherapeutic intervention,
- Volunteers
- 88 people
- Sponsor
- University of Geneva, Switzerland
Schizophenia Disorder, Schizoaffective Disorder
Context-Aware Mobile Intervention for Social Recovery in Serious Mental Illness (R33)
This randomized clinical trial will test a new technology-supported blended intervention, mobile Social Interaction Therapy by Exposure (mSITE), that targets social engagement in consumers with serious mental illness.
- Trial name
- NCT06865937
- Testing
- Mobile Intervention for Social Recovery in Serious Mental Illness (mSITE), Supportive Contact (SC)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of California, San Diego
Smoking Cessation, Schizophenia Disorder
Effects of Smoking on Network Connectivity in Patients With Schizophrenia Symptoms in Scz Patients
The prevalence of smoking among people with schizophrenia (SCZ) is substantially higher at 54% to 90% (McClave et al., 2010). About half of all deaths amongst people with scz are attributed to smoking-related diseases and cancer…
- Trial name
- ACT (NCT07441928)
- Testing
- Acceptance and Commitment Therapy (ACT-SC), 5A model (Ask, Assess, Advice, Assist & Arrange) smoking cessation intervention (5A-SC)
- Where
- 5 sites in Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University