Clinical trials: Schizophrenia and Disorders With Psychotic Features
Overweight and Obesity, Metabolic Cardiovascular Syndrome
The Effects of Psyllium Seed on Body Weight and Metabolic Syndrome Indicators in Patients with Schizophrenia
The research employs a quasi-experimental design, aiming to enroll 24 hospitalized patients with schizophrenia from 2hospitals in the central region, guided by G Power calculations.
- Conditions
- Overweight and Obesity, Metabolic Cardiovascular Syndrome, Schizophrenia, Disorganized
- Trial name
- NCT06789471
- Testing
- psyllium husk
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ru-Shin Zhang
Schizophrenia
Subjective Well Being of Schizophrenic Patients in Greece
Non-interventional study aiming to provide data on the subjective effects of antipsychotic medication assessing subjective well-being and global functioning of patients with Schizophrenia under antipsychotic medication.
- Trial name
- AURA (NCT00857064)
- Where
- 24 sites in Greece
- Volunteers
- 600 people
- Sponsor
- AstraZeneca
Psychosis, Schizoaffective Disorder
OnTrack>An Online Role-Playing Game: A Small Business Innovation Research (SBIR) Grant
Our team will develop a prototype game (OnTrack>The Game) in which users play the role of a person who has experienced First Episode Psychosis and move through animated role-playing scenarios, learning practical tips for engaging…
- Conditions
- Psychosis, Schizoaffective Disorder, Schizophrenia
- Trial name
- NCT02415764
- Testing
- Behavioral/Attitudinal OnTrack Role-Playing Game
- Where
- 2 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Center for Social Innovation, Massachusetts
Schizophrenia
Magnetic Stimulation as a Treatment for Auditory Hallucinations in Schizophrenia
Schizophrenia is a chronic, severe, and disabling brain disease. Auditory hallucinations are the most frequent symptoms with an incident of 50% to 70% in patients.
- Trial name
- NCT00186771
- Testing
- Paired Pulse
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Schizophrenia
Potential Intervention Strategy With Folic Acid and Vitamin B12 in Patients With Schizophrenia
The investigators study aims are: 1. To investigate folate, vitamin B12, and homocysteine levels in patients with schizophrenia. 2.
- Trial name
- NCT02916121
- Testing
- folic acid 5 mg/cap
- Where
- Taiwan
- Volunteers
- 88 people
- Sponsor
- Taipei Medical University WanFang Hospital
Social Phobia, Psychosis
Manualized Group Cognitive-behavioral Therapy for Social Anxiety in First Episode Psychosis
Social anxiety represents one of the most prevalent comorbid conditions in schizophrenia and related psychosis. Schizophrenia patients with comorbid social anxiety often exhibit impaired social functioning, an increased risk for…
- Trial name
- NCT02294409
- Testing
- Manualized group Cognitive-behavioral therapy (CBT) for social anxiety in first episode psychosis, Group Computer assisted cognitive remediation therapy
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- Douglas Mental Health University Institute
Prodromal Symptoms, Psychosis
DMHI for At-Risk College Students
The goal of this clinical trial is to learn if a single-session digital intervention (SPARK Coping) is acceptable, usable, and demonstrates a preliminary signal of efficacy in reducing symptom-related distress and increasing…
- Trial name
- NCT06608498
- Testing
- SPARK Coping
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Washington
Schizophrenia
Switching Medication to Treat Schizophrenia
This study will evaluate the effectiveness of switching medications in decreasing schizophrenia symptoms in individuals who are currently taking an antipsychotic medication for the treatment of schizophrenia.
- Trial name
- NCT00044655
- Testing
- Risperidone, Olanzapine, Ziprasidone
- Volunteers
- 219 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autoimmune Diseases, Mental Disorders Diagnosed in Childhood
Treatment of Childhood Onset Psychiatric Disorders With Intravenous Immunoglobulin (IVIg)
Recent research studies of early onset-obsessive compulsive disorder (OCD) and Tourette's syndrome have questioned whether autoimmunity could play a role in the development of these conditions.
- Conditions
- Autoimmune Diseases, Mental Disorders Diagnosed in Childhood, Schizophrenia
- Trial name
- NCT00001768
- Testing
- Intravenous immunoglobulin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Mental Health (NIMH)
Schizophrenia, Oxytocin
Adult Study Oxytocin - Behavioral
In this study, investigators will examine the behavioral effects and neurophysiological mechanisms of the pro-social neuropeptide oxytocin in patients with recent-onset schizophrenia and other psychotic disorders.
- Conditions
- Schizophrenia, Oxytocin, Social Cognition, Psychotic Disorders
- Trial name
- ASO-Behavioral (NCT02567032)
- Testing
- Oxytocin, Saline Nasal Spray
- Where
- 2 sites in United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Psychomotor Agitation, Acute Disease
IMPACT: A Study to Explore the Efficacy and Safety of Paliperidone ER in Patients With Acute Agitation
This study will investigate the effect of paliperidone ER (in combination with or without benzodiazepines) in patients presenting with symptoms of agitation and/or aggression in the context of psychosis, and will generate data…
- Trial name
- NCT01050478
- Testing
- Paliperidone ER, Benzodiazepine
- Where
- 14 sites in Belgium
- Volunteers
- 56 people
- Sponsor
- Janssen Cilag N.V./S.A.
Schizophrenia, Schizo Affective Disorder
Memantine Effects on Sensorimotor Gating and Neurocognition in Schizophrenia
This application seeks to determine if neurophysiological metrics of memantine (MEM)-enhanced early auditory information processing (EAIP) in schizophrenia (SZ) mediate gains in auditory processing fidelity (APF) and auditory…
- Conditions
- Schizophrenia, Schizo Affective Disorder, Schizoaffective Disorder, Healthy
- Trial name
- NCT03860597
- Testing
- Memantine
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Schizophrenia
Serum Clozapine and Cognition
This study aim to investigate the relationship between serum levels of clozapine and cognitive performance in patients with ICD-10 Schizophrenia and treated with clozapine monotherapy.
- Trial name
- NCT00951418
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Care Burden, Schizophrenia
The Effect of Acceptance and Commitment Therapy Intervention on Caregiver Burden in Caregivers of Schizophrenia Patients
The aim of this study was to learn the effects of Acceptance and Commitment Therapy based stress management program on psychological flexibility and caregiver burden in caregivers of schizophrenia patients.
- Conditions
- Care Burden, Schizophrenia, Caregiver Mental Health
- Trial name
- NCT06799325
- Testing
- acceptance and commitment therapy based stress management program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cumhuriyet University
Schizophrenia, Psychopathology
fMRI Study of Nicotinic Effect on Neurophysiology of Schizophrenia
Background: Individuals who have schizophrenia are significantly more likely to smoke than the general population, which leads to increased smoking-related illnesses and high rates of nicotine dependence.
- Conditions
- Schizophrenia, Psychopathology, Nicotine Dependence
- Trial name
- NCT01046526
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Diabetes Mellitus, Schizophrenia
Diabetes Screening, Risk Management and Disease Management in a High-Risk Mental Health Population
Family physicians are the primary health care providers for complex patients such as persons with serious mental illness. The psychiatric needs of these patients could take attention away from management of health problems and…
- Conditions
- Diabetes Mellitus, Schizophrenia, Psychotic Disorders
- Trial name
- NCT00253240
- Testing
- Screening, Management
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Schizophrenia
Quetiapine XR in Schizophrenic Patients
The purpose of the study is to determine the effect of Quetiapine in patients with schizophrenia induced by cannabis abuse.
- Trial name
- NCT01071135
- Testing
- Quetiapine XR
- Where
- 3 sites in Germany
- Volunteers
- 5 people
- Sponsor
- Hannover Medical School
Toxoplasmosis, Schizophrenia
Pilot Trial of Valproate as Adjunctive Treatment for Toxoplasma Gondii Infection in Early Course Schizophrenia
This is an exploratory study in Egypt that will combine a treatment trial among early course schizophrenia (ECSZ) patients with key analyses suggested by rodent studies.
- Trial name
- NCT02011750
- Testing
- Sodium Valproate treatment
- Where
- Egypt
- Volunteers
- 109 people
- Sponsor
- University of Pittsburgh
Schizophrenia, Bipolar Disorder
Prevalence of Diabetes Mellitus Among Patients Treated With Atypical and Conventional Antipsychotics
This pilot study hypothesizes that diagnosed and undiagnosed prevalence of diabetes mellitus may differ across antipsychotioc medications in a community mental health center.
- Conditions
- Schizophrenia, Bipolar Disorder, Diabetes Mellitus
- Trial name
- NCT00224276
- Volunteers
- 100 people
- Sponsor
- Yale University
Schizophrenia
Transcranial Direct Current Stimulation (tDCS) for Treatment of Negative Syndrome in Patients With Schizophrenia
Transcranial direct current stimulation (tDCS) showed beneficial effects on cognition in healthy subjects and depressed patients.
- Trial name
- NCT01378078
- Testing
- eldith DC-stimulator (neuroconn, Ilmenau, Germany)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Ludwig-Maximilians - University of Munich
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