Clinical trials: Sciatic Nerve Block
Diabetes Type 2
Evaluation of Block Duration in Type 2 Diabetes Patients
Diabete animal studies demonstrated a longer period recovery after local anesthetic injection (perineural administration). No clinical study demonstrated a prolonged nerve block duration in diabete type 2 patients after…
- Trial name
- Diabeteblock (NCT01704612)
- Testing
- ropivacaine
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Pierre and Marie Curie University
Feedback
Simulation-based Training for Ultrasound-guided Popliteal Sciatic Nerve Block
The goal of this study is to evaluate whether remote asynchronous feedback is non-inferior to direct synchronous feedback during simulation-based training for ultrasound-guided popliteal sciatic nerve block performance.
- Trial name
- NCT07659145
- Testing
- Asynchronous distance feedback, Synchronous direct feedback
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Sciatica Acute, Sciatica Pain
Ultrasound-guided Transgluteal Sciatic Nerve Hydrodissection for the Treatment of Sciatica in the Emergency Department
The goal of this observational study is to see whether it would be feasible to treat patients who come to the emergency department with pain related to sciatica using an ultrasound guided injection of dextrose in water solution…
- Trial name
- NCT07588126
- Testing
- Ultrasound guided transgluteal sciatic nerve hydrodissection
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Kaiser Permanente
Knee Arthritis
Spinal Anesthesia Versus Combined Sciatic-femoral Nerve Block for Outpatient Knee Arthroscopy
The aim of the study is to compare the time of home discharge in day-case patients receiving either a spinal anesthesia or a combined sciatic-femoral nerve block for knee arthroscopy
- Trial name
- NCT02384915
- Testing
- prilocaine, mepivacaine, Sciatic-femoral Nerve Block
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ASST Gaetano Pini-CTO
Postoperative Pain
Femoral or Sciatic Nerve Block to Provide Analgesia After Proximal Tibial Osteotomy
Proximal tibial osteotomy is associated with moderate to severe postoperative pain. The proximal part of the tibia is innervated by branches from the femoral nerve anteriorly and the sciatic nerve posteriorly.
- Trial name
- NCT05728294
- Testing
- Femoral nerve block with ropivacaine 0.5%, 20 ml, Sciatic nerve block with ropivacaine 0.5%, 20 ml
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Postoperative Cognitive Complications
Spinal Anesthesia Vs. Neve Block in Risk of Cognitive Decline
Hip fracture is a potentially devastating event, and serious surgical and medical complications occur frequently especially for elderly patients. Delirium is one of the common complications after hip surgery.
- Trial name
- NCT06963229
- Testing
- Spinal Anesthesia (bupivacaine), Peripheral Nerve Block
- Where
- Lebanon
- Volunteers
- 50 people
- Sponsor
- Makassed General Hospital
Orthopedic Disorder, Total Knee Replacement
Combined Adductor&Sciatic Nerve Block vs Femoral&Sciatic Nerve Block in Total Knee Replacement Surgery
Knee joints, one of the largest and most functional joints of the human body, have great features to provide ideal body posture and movement.
- Conditions
- Orthopedic Disorder, Total Knee Replacement, Post Operative Pain, Surgery
- Trial name
- NCT05648708
- Testing
- Combine Adductor Canal & Sciatic Nerve Block, Combine Femoral & Sciatic Nerve Block, Bupivacaine and prilocaine hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Lower Leg Surgery, e.g. Ankle Fractures
Ultrasound-guided Nerve Blocks for the Sciatic and Saphenous Nerves: Characteristics of the Single Penetration Dual Injection (SPEDI) Technique
Background and aims: Ultrasound-guided (USG) nerve blocks of the sciatic nerve (popliteal level = PL) and the saphenous nerve (mid-femoral level = MFL) provides analgesia following leg surgery.
- Trial name
- NCT01815372
- Testing
- Single penetration dual injection (SPEDI) block technique to block the sciatic and the saphenous nerve with one needle penetration of the skin, The classical popliteal sciatic nerve block combined with the mid-femoral saphenous nerve block
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Bispebjerg Hospital
Post Operative Pain
Sciatic Nerve Block, Adductor Canal Block, or IPACK Block
Comparison between local anesthetic infiltration between the popliteal artery and the capsule of the knee (IPACK) versus adductor canal block (ACB) or sciatic nerve block (anterior approach) in combination with femoral nerve…
- Trial name
- NCT05684107
- Testing
- IPACK block, adductor canal block, sciatic nerve block
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Menoufia University
Orthopedic Surgery of Lower Extremity
Evaluation of Continuous Saphenous Nerve Block to Supplement a Continuous Sciatic Nerve Block After Ankle Surgery
A nerve block catheter is a small tube placed next to a nerve through a needle, and the needle is then removed. Numbing medicine is dripped through the tube to reduce pain sensation from the nerve.
- Trial name
- NCT01167907
- Testing
- 0.2% ropivacaine, saline
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Wake Forest University Health Sciences
Hip Arthroplasty Replacement, Post Operative Analgesia
Comparison of Pericapsular Nerve Group (PENG) Block With a Combined Femoral, Sciatic, Lateral Femoral Cutaneous Nerve Block for Postoperative Analgesia in Secondary Total Hip Arthroplasty; (REVPET)
The aim of this clinical trial is to compare the analgesic effect of a pericapsular nerve group (PENG) block with a combined femoral, sciatic, lateral femoral cutaneous nerve block for postoperative analgesia in patients…
- Conditions
- Hip Arthroplasty Replacement, Post Operative Analgesia, Post Operative Pain, Acute
- Trial name
- REVPET (NCT07109388)
- Testing
- Pericapsular nerve group (PENG) block with 0.75% ropivacaine guided by ultrasound, Femoral, sciatic and lateral femoral cutaneous nerve block with 0.375% ropivacaine
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Pain
Dexamethasone & Bupivacaine vs Bupivacaine Alone in Combined Femoral and Sciatic Nerve Block for Perioperative Analgesia in Patients Undergoing Lower Limb Surgeries
In regional anesthesia local anaesthetics alone provide analgesia for not more than 4-8 hours. Increasing the duration of local anaesthetic action is often desirable because it prolongs surgical anaesthesia and analgesia.
- Trial name
- NCT02576782
- Testing
- Perineural Dexamethasone and bupivacaine, Systemic Dexamethasone plus perineural bupivacaine, intravenous saline plus perineural bupivacaine
- Volunteers
- 63 people
- Sponsor
- Sherif Mohamed Abd el moneim Soaida, MD
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
Onset Time of Nerve Block: A Comparison of Two Injection Locations in Patients Having Lower Leg/ Foot Surgery
The purpose of this study is to compare injecting local anesthetic (numbing medication) in different patterns around a major nerve in the leg.
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/or Foot
- Trial name
- NCT01542840
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Orthopedic Disorders, Foot Diseases
Efficacy of Ultrasound-Guided Local Anesthetic Injection Into or Around the Sciatic Nerve for Lower Limb Anesthesia
This study was designed to assess whether the injection of local anesthetic into the nerve (intraneural), as opposed to around it (perineural), requires a shorter time to develop surgical anesthesia of the lower leg.
- Conditions
- Orthopedic Disorders, Foot Diseases, Injuries, Leg, Injuries, Foot
- Trial name
- NCT01999647
- Testing
- Intraneural Injection for Subgluteal Sciatic Nerve Block, Perineural Injection for Subgluteal Sciatic Nerve Block, Femoral Nerve Block
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- University of Parma
Major Ankle Surgery
Saphenous Nerve Block: Single Shot Versus Continuous Infusion to Supplement a Continuous Sciatic Nerve Block After Major Ankle Surgery
The most useful method to manage pain after major ankle surgery is infusion of local analgesics with a catheter close to the sciatic nerve.
- Trial name
- NCT01445210
- Testing
- Continuous saphenous nerve block
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Diabetic Neuropathy
Characteristics of Popliteal Sciatic Nerve Block in Patients With and Without Diabetic Neuropathy
Background Between 25 and 55% of diabetic patients develop neuropathy secondary to hyperglycemia. High resolution bedside ultrasound has been demonstrated to be a useful tool to detect the presence of neuropathy prior to block…
- Trial name
- NCT02076945
- Testing
- US-guided sciatic block at the popliteal crease (30 mL1:1 mixture of lidocaine 1% and bupivacaine 0.5%)
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Pain, Postoperative, Osteoarthritis, Knee
Comparing Local Anesthetic Injections to Nerve Blocks for Pain Control After Total Knee Replacement
Why are we doing this study? People who have knee replacement surgery often feel pain afterward. Doctors use different methods to control this pain.
- Conditions
- Pain, Postoperative, Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Trial name
- LIA-PNB-TKA (NCT07744503)
- Testing
- Continuous Femoral and Sciatic Nerve Block (Ropivacaine), Local Infiltration Analgesia (Ropivacaine, Ketorolac, Epinephrine)
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Christopher Male
Primary Condition: Nerve Block, Secondary Condition: Catheter Displacement
Performance of a Novel Concept for Internal Fixation of a Novel Peripheral Nerve Block Catheter
The goal of this study is to test a new type of nerve block catheter (a thin, flexible tube used to deliver pain medication). Researchers want to see if this new design stays in its original position better than current catheters…
- Conditions
- Primary Condition: Nerve Block, Secondary Condition: Catheter Displacement, Focus of Study: Sciatic Nerve
- Trial name
- NCT07385872
- Testing
- Novel Internal Fixation Nerve Block Catheter - Sciatic Nerve, Novel Internal Fixation Nerve Block Catheter - Saphenous nerve
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Nordsjaellands Hospital
Nerve Block; Pain Medication
Obturator Nerve Block With Femoral and Sciatic Block
The purpose of this study is to evaluate how many patients require the addition of the obturator nerve block in the recovery room after the total knee surgery.
- Trial name
- NCT01409460
- Testing
- Oburator Nerve block
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Trinity Health Of New England
Anesthesia
Application of Combined Lumbar Plexus and Sciatic Nerve Block
The research is to study the effectiveness and safety of combined lumbar plexus and sciatic nerve block by the guide of peripheral nerve stimulator (PNS) in unilateral knee replacement.There have be some papers which supported…
- Trial name
- NCT02084368
- Testing
- Nerve block, Combined spinal and epidural anesthesia, Ropivacaine
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command