Clinical trials: Sciatica Pain
Lumbar Radiculopathy, Sciatica
Dose Dependent Steroid Injections
This study aims to evaluate the efficacy of interlaminar steroid injections at treating pain in lumbar radiculopathy at varying doses, to evaluate the efficacy of interlaminar steroid injections at improving quality of life and…
- Conditions
- Lumbar Radiculopathy, Sciatica, Back Pain With Radiation
- Trial name
- NCT07494136
- Testing
- Triamcinolone 10 Mg/mL Injectable Suspension, Triamcinolone 40 Mg/mL Injectable Suspension, Triamcinolone 80 Mg/mL Injectable Suspension
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Miami
Sciatica
Efficacy of Epidural Etanercept in the Treatment of Sciatica
Tumor necrosis factor (TNF)-alpha has been strongly implicated as a major contributing factor for the development of radiculopathy.
- Trial name
- NCT00364572
- Testing
- epidural injection of etanercept
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Johns Hopkins University
Sciatica
The Efficacy of Oral Steroids in the Treatment of Acute Sciatica
Sciatica (lumbosacral radiculopathy) is a common diagnosis in primary care, occurring in approximately one percent of all patients with acute low back pain.
- Trial name
- NCT00317447
- Testing
- Oral Prednisone
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Kaiser Permanente
Low Back Pain, Sciatica
Management Strategies for Patients With Low Back Pain and Sciatica
Low back pain and sciatica is a common condition resulting in high costs and disability for society and affected individuals. Presently there is a lack of evidence for what treatments may help this condition early in the course…
- Conditions
- Low Back Pain, Sciatica, Physical Therapy
- Trial name
- NCT02391350
- Testing
- Education and re-assurance, Physical Therapy
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Utah
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Lumbar Disc Herniation
SI-6603 (Condoliase) Study for Lumbar Disc Herniation (Discovery 6603 Study)
This study is to evaluate the effectiveness of a single-dose intervertebral disc injection of SI-6603 in subjects with lumbar disc herniation (LDH)
- Trial name
- NCT03607838
- Testing
- SI-6603
- Where
- 67 sites in United States
- Volunteers
- 352 people
- Sponsor
- Seikagaku Corporation
Low Back Pain, Sciatica
Long-Term Course of Korean Medicine Treatment for Lumbar Disc Herniation
This observational study will assess the long-term course and effect of Korean medicine treatment in lumbar intervertebral disc herniation patients who received integrative Korean medicine treatment for 24 weeks as part of a…
- Conditions
- Low Back Pain, Sciatica, Intervertebral Disc Displacement
- Trial name
- NCT03426215
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Jaseng Medical Foundation
Sciatica, Intervertebral Disc Displacement
Effects of Shinbaro Pharmacopuncture in Sciatic Pain Patients With Lumbar Disc Herniation
This trial will evaluate the comparative clinical effectiveness of pharmacopuncture for severe non-acute sciatic pain patients diagnosed with lumbar disc herniation (LDH) with usual care of conventional medicine and that of…
- Trial name
- NCT02384928
- Testing
- Shinbaro pharmacopuncture, Acupuncture, Conventional medicine
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Jaseng Medical Foundation
Lumbar Disc Herniation, Low Back Pain
Effect of Neurodynamic Mobilization in Patients With Lumbar Disc Herniation
The objective of this randomized controlled trial was to investigate the effects of neurodynamic mobilization on pain intensity, normal joint motion, neurodynamics, functional level, and disability in patients with lumbar disc…
- Trial name
- NCT07203560
- Testing
- Neurodynamic Mobilization, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Aydin Adnan Menderes University
Lumbosacral Radiculopathy
Does Magnetic Resonance Imaging (MRI) Improve Interventional Outcomes for Lumbosacral Radiculopathy?
Epidural steroid injections (ESI) are the most frequently performed procedures in pain clinics. When performing ESI, there is no consensus about how to best select candidates for this intervention, and which level(s) to inject.
- Trial name
- NCT00826124
- Testing
- Epidural steroid injection, Magnetic Resonance Imaging (MRI)
- Where
- 2 sites in United States
- Volunteers
- 131 people
- Sponsor
- Johns Hopkins University
Piriformis Syndrome
Interfascial Hydrodissection Added to Ultrasound-Guided Piriformis Injection for Piriformis Syndrome
The gluteus maximus overlies the piriformis muscle and forms a broad fascial interface with it. Restricted movement, increased tension, or adhesions between these tissue layers may contribute to persistent buttock pain in…
- Trial name
- NCT07813455
- Testing
- Ultrasound-Guided Piriformis Injection, Ultrasound-Guided Interfascial Hydrodissection, Standardized Home-Based Piriformis Stretching Program
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Back Pain
Could a Simple Information Booklet Modify Low Back Pain Patients Beliefs After Lumbar Discectomy?
The purpose of this study is to translate and assess an evidence based educational booklet on low back pain patients beliefs after lumbar discectomy.
- Trial name
- NCT00761111
- Testing
- Assessment of the Your Back Operation
- Volunteers
- 140 people
- Sponsor
- University Hospital, Clermont-Ferrand
Sciatica
Neuraxial Pethidine After Lumbar Surgery Trial
The hypothesis is that epidural pethidine is an effective form of pain relief following lumbar spinal surgery, resulting in significantly lower usage of concomitantly administered (intravenous) patient-controlled analgesia (PCA)…
- Trial name
- NCT00163553
- Testing
- Pethidine
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- Austin Health
Sciatica
Efficacy of Sciatic Nerve Electrical Stimulation and Therapeutic Exercise in the Management of Low-back Related Leg Pain
This clinical study focuses on people who experience long-term low-back related leg pain (commonly called sciatica). This type of pain is often associated with nerve irritation or compression in the lower spine and can cause…
- Trial name
- NCT07373808
- Testing
- Percutaneous Electrical Nerve Stimulation, Transcutaneous Electrical Nerve Stimulation, Real Dry Needling (without Percutaneous Electrical Nerve Stimulation)
- Where
- Spain
- Volunteers
- 88 people
- Sponsor
- Universidad Complutense de Madrid
Sciatica Acute, Sciatica
COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICA
The goal of this clinical trial is to compare different combinations of diclofenac with diclofenac monotherapy in acute sciatica.
- Trial name
- EDCLAS (NCT05626140)
- Testing
- Lacosamide 50 MG Oral Tablet [Vimpat], Codeine Phosphate, Diclofenac Sodium
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Pakistan Institute of Medical Sciences
Lumbosacral Radicular Pain
Corticosteroid Lumbar Epidural Analgesia for Radiculopathy
This is a research study of SP-102, an experimental medication designed to relieve pain in patients with a specific type of leg pain.
- Trial name
- NCT03372161
- Testing
- SP-102
- Where
- 37 sites in United States
- Volunteers
- 401 people
- Sponsor
- Scilex Pharmaceuticals, Inc.
Chronic Pain, Sciatica
NAPS: Non-awake Versus Awake Placement of Spinal Cord Stimulators
The primary objective is to demonstrate the safety and efficacy of a non-awake implantation method (EMG neuromonitoring) of a SCS paddle lead as compared to an awake implantation method (with local anesthesia and patient…
- Conditions
- Chronic Pain, Sciatica, Failed Back Surgery Syndrome
- Trial name
- NAPS (NCT02284542)
- Testing
- Awake, Non-Awake
- Where
- 4 sites in United States
- Volunteers
- 34 people
- Sponsor
- St. Luke's Hospital, Pennsylvania
Sciatica Due to Intervertebral Disc Disorder
Electroacupuncture for Sciatica Due to Intervertebral Disc Displacement
This multicenter randomized controlled trial (RCT) will evaluate the therapeutic effectiveness and health-economics of electroacupuncture for sciatica due to intervertebral disc displacement in 3 compared groups…
- Trial name
- NCT02087462
- Testing
- Electroacupuncture (EA), Traction, Voltaren
- Where
- China
- Volunteers
- 324 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
RADICULAR PAIN
Efficacy of Intravenous Dexamethasone for Acute Disc Herniation-Induced Sciatica
Acute low back pain is one of the most common reasons for all physician visits(1). Phospholipase A2 (PLA2), a potent inflammatory mediator, has demonstrated to be released by discs following injury(4).
- Trial name
- NCT00516009
- Testing
- DEXAMETHASONE
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Ziv Hospital
Back Pain, Back Pain, Low
Aromatherapy Randomization of Pain Management in Adults
Pain control for acute isolated back pain and sciatica is a nebulous and often illusive task in the emergency department, and a challenge face everyday by emergency medicine physicians.
- Conditions
- Back Pain, Back Pain, Low, Sciatica
- Trial name
- AROMA (NCT03377088)
- Testing
- Rose oil, Almond Oil
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stony Brook University