Clinical trials: Scoliosis
Spine Deformity, Idiopathic Scoliosis
Advanced SPinal Innovations With Robotics and Enabling Technology Registry
Creation of a pediatric robotic spine surgery registry will allow for data collection and analysis on the coupled use of robotics and navigation, as well as patient-specific rods in pediatric spine deformity surgery across…
- Conditions
- Spine Deformity, Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis, Spondylolisthesis
- Trial name
- ASPIRE (NCT05071144)
- Where
- 10 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Adolescent Idiopathic Scoliosis
Safety and Efficacy Study of Spinal Tethering
This study is an opportunity to gather long term safety and efficacy information from patients who have had their scoliosis treated via anterior vertebral body tethering (VBT).
- Trial name
- NCT02897453
- Testing
- The Spinal Tethering System
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis
Kids With Iron Deficiency and Scoliosis
This study is a randomized controlled trial of preoperative oral iron supplementation, to identify whether iron deficiency is a modifiable risk factor for adverse surgical outcomes such as red blood cell transfusion and…
- Conditions
- Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis, Perioperative/Postoperative Complications, Iron Deficiencies
- Trial name
- KIDS (NCT06042699)
- Testing
- Oral ferrous sulfate
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Columbia University
Adolescent Idiopathic Scoliosis, Diaphragmatic Manual Techniques
Three-Dimensional Scoliosis Exercises and Diaphragmatic Manual Techniques in Adolescents With Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional deformity of the spine that emerges during growth and is characterized by lateral curvature, vertebral rotation, and trunk asymmetry.
- Conditions
- Adolescent Idiopathic Scoliosis, Diaphragmatic Manual Techniques, Schroth Exercises
- Trial name
- NCT07683533
- Testing
- Diaphragmatic manual techniques, Schroth exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Akdeniz University
Adolescent Idiopathic Scoliosis
An Aerobic Exercising Program on Respiratory Muscle Strength in Patients With Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis (AIS) can change the respiratory dynamics and performance of the inspiratory and expiratory muscles, affecting ventilatory capacity.
- Trial name
- NCT00886652
- Testing
- Aerobic exercise program
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Irmandade da Santa Casa de Misericordia de Sao Paulo
Adolescent Idiopathic Scoliosis
Evaluation of Adam's Forward Bend Test and Smartphone Application in Screening of Adolescent Idiopathic Scoliosis
Scoliosis is a lateral curvature of the spine when the Cobb´s angle more than 10˚ on the frontal plane. Curve detection before skeletal maturation gives a good opportunity for early treatment or prevention of curve progression.
- Trial name
- NCT04092335
- Where
- Egypt
- Volunteers
- 840 people
- Sponsor
- Cairo University
Posture, Vertebral Compression Fracture
The Spine Kinematics and Center of Pressure Excursion During Functional Task Vertebral Compression Fractures Subjects
This study aimed to assess the sensory and kinematic components of the limits of stability (LOS) test in patients with vertebral compression fracture (VCF) .
- Trial name
- NCT04135755
- Testing
- no drug intervention
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Scoliosis; Adolescence, Degenerative Disc Disease
Personalized Spine Study Group Registry
As a registry, the primary objective of the study is a data collection initiative. The study will collect clinical and radiographic outcomes of patients implanted with Medicrea's PSR.
- Conditions
- Scoliosis; Adolescence, Degenerative Disc Disease, Spinal Fusion, Kyphoscoliosis
- Trial name
- NCT03843476
- Testing
- Patient Specific Rod
- Sponsor
- Medicrea, USA Corp.
Idiopathic Scoliosis
Assessment of Dynamic Balance in Idiopathic Scoliosis Compared to Normal Subjects
The purpose of this study is to assess dynamic balance in females with adolescent idiopathic scoliosis compared to normal subjects.
- Trial name
- NCT06219772
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hyperkyphosis, Adolescent Idiopathic Scoliosis
Validation of Clinical Assessment of Spinal Stiffness
This study aims to validate and verify the reliability of the clinical measures used in the daily routine by doctors and therapists that allow assessing the spinal stiffness in all spatial planes.
- Trial name
- NCT05924581
- Testing
- Clinical assessment of spinal stiffness
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Istituto Scientifico Italiano Colonna Vertebrale
Spondylolisthesis, Scoliosis
A Prospective Study of Instrumented, Posterolateral Lumbar Fusions (PLF) With OsteoAMP®
OsteoAMP is a novel allograft bone graft substitute (BGS) that has been processed to retain multiple endogenous growth factors for use in spinal fusion.
- Conditions
- Spondylolisthesis, Scoliosis, Intervertebral Disc Disease
- Trial name
- NCT02225444
- Testing
- OsteoAMP
- Where
- 9 sites in United States
- Volunteers
- 42 people
- Sponsor
- Bioventus LLC
Scoliosis Patients
Changes in Cerebral Oxygenation Related to Intraoperative Position Changes
This is a prospective, observational study. This study will assess the effect of temporary changes in body position (supine, head of bed elevated 30 degrees, head of bed elevated 60 degrees) in anesthetized patients.
- Trial name
- NCT06910228
- Testing
- Near infrared spectroscopy (NIRS)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Joseph D. Tobias
Adolescent Idiopathic Scoliosis, Respiratory Depression
Anesthetic Optimization in Scoliosis Surgery
The standard anesthetic care plan for people having adolescent idiopathic scoliosis surgery will be accompanied by a pharmacokinetic simulation of the administered drugs to suggest opportunities to adjust drug doses to achieve…
- Conditions
- Adolescent Idiopathic Scoliosis, Respiratory Depression, Postoperative Pain
- Trial name
- AIS (NCT02481570)
- Testing
- pharmacokinetic simulation
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Florida
Scoliosis, Adolescent Idiopathic Scoliosis
The Comparison of Core Stabilization Exercise With Scientific Exercise Approach to Scoliosis in Idiopathic Scoliosis
Scoliosis specific exercises have been shown to improve curve progression but there have been few studies that compare the different exercise approaches in adolescent idiopathic scoliosis (AIS).
- Trial name
- NCT02978820
- Testing
- SEAS exercise, CS exercise
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Neurofibromatosis 1, Scoliosis
Genetic Evaluation of NF1 and Scoliosis Patients
Neurofibromatosis (NF) is a common genetic disorder that cause tumors to grow along various types of nerves and, in addition, can affect the development of bones and skin. It occurs in 1:4000 persons.
- Trial name
- NCT01776125
- Testing
- Cheek swab
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Minnesota
Adolescent Idiopathic Scoliosis
Pedicle Screw Usage in Conventional Fixation Pattern Constructs Compared to Thoracic Hook Constructs in Scoliosis
Scoliosis is a deformity in which there is an abnormal curvature of the spine. Surgery is the main method of correcting this deformity. Rods are attached to the spine to make it strait.
- Trial name
- NCT01581021
- Testing
- Pedicle screws, Laminar Hooks
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Mississippi Medical Center
Scoliosis, Quality of Life
Psychometric Properties of the Turkish Version of the Staffordshire Adolescent Idiopathic Scoliosis Questionnaire
Patient-Reported Outcome Measures (PROMs) have gained increasing importance in scoliosis research in recent years. Although widely used instruments such as the Scoliosis Research Society-22 (SRS-22) include domains related to…
- Trial name
- NCT07676019
- Testing
- Turkish Version of the Staffordshire Questionnaire for Adolescent Idiopathic Scoliosis (SQAIS)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Acibadem University
Arthrodesis
Corrections of Anterior Imbalances by Posterior Instrumentation and Osteotomies
Several deformities of the spine exist such as the anterior imbalance. These deformities can generate functional discomfort and limit the patient's quality of life.
- Trial name
- OTP (NCT05100732)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
Spinal Fusion, Nausea and Vomiting, Postoperative
Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery
This research trial will measure how useful Aprepitant is in preventing nausea and vomiting in children having surgery to correct scoliosis (curvature of the spine).
- Conditions
- Spinal Fusion, Nausea and Vomiting, Postoperative, Anesthesia
- Trial name
- NCT06357234
- Testing
- Aprepitant
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- IWK Health Centre
Scoliosis Patients
Hemoglobin Monitoring in Scoliosis Surgery
The study is planned to include patients who will undergo elective scoliosis surgery under general anesthesia at the Health Sciences University Antalya Education and Research Hospital.
- Trial name
- NCT07054411
- Testing
- Radical-7 Pulse CO-Oximeter
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Erhan Ozyurt