Clinical trials: Scoliosis Lumbar Region
Spinal Muscular Atrophy, Spine Deformity
Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy
The primary objective of the clinical investigation is to demonstrate successful clinical use of the ThecaFlex DRx™ System in delivering nusinersen in subjects with spinal muscular atrophy (SMA).
- Conditions
- Spinal Muscular Atrophy, Spine Deformity, Scoliosis
- Trial name
- PIERRE (NCT05866419)
- Testing
- ThecaFlex DRx System
- Where
- 21 sites in United States, Germany and 3 more
- Volunteers
- 90 people
- Sponsor
- Alcyone Therapeutics, Inc
Degenerative Scoliosis, Scoliosis Lumbar Region
Degenerative Lumbar Scoliosis
This is a retrospective, observational multi-center study. The participants undergone lumbar spine surgery for degenerative lumbar scoliosis and followed up for at least 2 years are retrospectively enrolled from 8 centers.
- Trial name
- DLS (NCT05485636)
- Where
- 8 sites in China
- Volunteers
- 640 people
- Sponsor
- Peking University Third Hospital
Degenerative Disc Disease
Interbody Systems: Post Market Clinical Follow-up Study
This is a prospective, multi-center study of subjects who will undergo spinal fusion surgery utilizing Stryker Interbody Systems that require post market clinical follow up (PMCF).
- Trial name
- NCT04911257
- Testing
- Cervical or Lumbar Spinal fusion
- Where
- 4 sites in United States
- Volunteers
- 28 people
- Sponsor
- K2M, Inc.
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Does Teicoplanin Powder Use In Lumbar Instrumentation Surgery Reduce Surgical Site Infection
Infection after spinal surgery is one of the serious complications. Spinal surgery infection can cause high morbidity, mortality, and costs.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Scoliosis Lumbar Region, Lumbar Spondylolisthesis
- Trial name
- NCT04341831
- Testing
- Teicoplanin
- Volunteers
- 120 people
- Sponsor
- Bezmialem Vakif University
Juvenile Idiopathic Lumbar Scoliosis
Yoga for Juvenile Idiopathic Scoliosis
We use one or at most two simple yoga poses to reverse juvenile idiopathic lumbar and thoracolumbar scoliosis in 8 - 12 year-olds. It involves daily practice of 5 - 7 minutes. Involvement is 4-8 months with two or three low-dose.
- Trial name
- JIS (NCT07818148)
- Testing
- Therapeutic yoga pose
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Manhattan Physical Medicine and Rehabilitation, LLP
Scoliosis Neuromuscular, Duchenne Muscular Dystrophy
Prevention of Scoliosis in Patients With Duchenne Muscular Dystrophy Using Portable Seat Device
This study will be conducted without blind method. The portable seat device devised to maintain lumbar lordosis will be made within 1 year after the loss of ambulation in the participants with Duchenne muscular dystrophy with…
- Conditions
- Scoliosis Neuromuscular, Duchenne Muscular Dystrophy, Lordosis Lumbar
- Trial name
- NCT03611244
- Testing
- Portable seat device devised to maintain lumbar lordosis
- Where
- 2 sites in South Korea
- Volunteers
- 98 people
- Sponsor
- Seoul National University Hospital
Adult Spinal Deformity, Degenerative Scoliosis
Gait and Paraspinal sEMG in Degenerative Spinal Diseases
This cross-sectional observational study aims to quantitatively compare three-dimensional gait parameters, surface electromyography (EMG) patterns, and radiological parameters among patients with different degenerative spinal…
- Conditions
- Adult Spinal Deformity, Degenerative Scoliosis, Sagittal Deformity, Sagittal Imbalance
- Trial name
- TDGKSEPDSD (NCT07309926)
- Testing
- Gait analysis and surface electromyography analysis
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Scoliosis Idiopathic, Fascia
Exercise Effects on Fascia, Low Back Pain, and Function in Scoliosis
The use of various muscle energy techniques to address fascial restrictions, in addition to three-dimensional correction within scoliosis-specific exercise approaches, suggests that these exercises may have different effects on…
- Conditions
- Scoliosis Idiopathic, Fascia, Low Back Pain
- Trial name
- NCT07418983
- Testing
- Scientific Exercise Approach to Scoliosis (SEAS) Exercises, Functional Individual Therapy of Scoliosis Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Hacettepe University
Sacroiliac Joint Disruption, Scoliosis Lumbar Region
SI Joint Stabilization in Long Fusion to the Pelvis
The purpose of this study is to compare outcomes of subjects undergoing multilevel lumbar fusion (MLF) surgery with and without the iFuse 3-D implants in the "bedrock" trajectory.
- Trial name
- SILVIA (NCT04062630)
- Testing
- iFuse 3-D in Bedrock Configuration, Multilevel Lumbar Fusion surgery
- Where
- 31 sites in United States, Australia and 3 more
- Volunteers
- 213 people
- Sponsor
- SI-BONE, Inc.
Degenerative Disc Disease, Degenerative Spondylolisthesis
Lumbar Interbody Implant Study
The objective of this study is to evaluate the safety and performance of NuVasive interbody implants when used during thoracic and/or lumbar spine surgery as measured by reported complications, radiographic outcomes, and…
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Scoliosis, Spinal Stenosis
- Trial name
- NCT04418830
- Where
- 16 sites in United States
- Volunteers
- 1,050 people
- Sponsor
- NuVasive
The Lumbar Spine Surgical Intervention, Arthrodesis
Evaluation of the Effect of Reiki on Pain After Lumbar Surgery
The goal of this clinical trial (prospective, comparative, and randomized double-blind study) is to learn if Reiki (a non-pharmacological intervention), when used alongside standard care, can treat and reduce postoperative pain…
- Conditions
- The Lumbar Spine Surgical Intervention, Arthrodesis, Severe Herniated Disc, Scoliosis
- Trial name
- REDAL (NCT07722117)
- Testing
- Reiki treatment and chirurgy
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Bizet
Degenerative Lumbar Disease, Scoliosis
Priority-Matching Correction Technique in Degenerative Lumbar Scoliosis
Surgical outcomes, including radiographic outcomes, patient-reported outcomes, postoperative complications, and revision surgery rates, were compared in patients with degenerative lumbar scoliosis (DLS) who underwent correction…
- Conditions
- Degenerative Lumbar Disease, Scoliosis, Degenerative Scoliosis
- Trial name
- PMCTDLS (NCT06470165)
- Testing
- Priority-matching correction technique in DLS, Traditional correction technique in DLS
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Degenerative Scoliosis
Clinical Study of Imaging and Endoplant-related Mechanical Complications After Long Segment Fixation and Fusion of Degenerative Lumbar Scoliosis (DLS)
There is a high probability of mechanical complications in patients with degenerative lumbar scoliosis after long segment fixation and fusion, and there are few studies on distal borderline kyphosis deformity/failure.
- Trial name
- NCT04960423
- Testing
- Long Segment Fixation and Fusion
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Degenerative Scoliosis
Degenerative Scoliosis
Several deformities of the spine exist such as degenerative lumbar scoliosis. These deformities can generate functional discomfort and limit the patient's quality of life.
- Trial name
- DS (NCT05105737)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
Arthrodesis
Corrections of Anterior Imbalances by Posterior Instrumentation and Osteotomies
Several deformities of the spine exist such as the anterior imbalance. These deformities can generate functional discomfort and limit the patient's quality of life.
- Trial name
- OTP (NCT05100732)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
Spondylolisthesis, Scoliosis
A Prospective Study of Instrumented, Posterolateral Lumbar Fusions (PLF) With OsteoAMP®
OsteoAMP is a novel allograft bone graft substitute (BGS) that has been processed to retain multiple endogenous growth factors for use in spinal fusion.
- Conditions
- Spondylolisthesis, Scoliosis, Intervertebral Disc Disease
- Trial name
- NCT02225444
- Testing
- OsteoAMP
- Where
- 9 sites in United States
- Volunteers
- 42 people
- Sponsor
- Bioventus LLC
Scoliosis; Adolescence, Adolescent Idiopathic Scoliosis, Thoracic Region
Massage Therapy After Thoracic or Lumbar Surgery
The purpose of this research is to look at the effect of massage therapy on the pain, anxiety, and quality of life that pediatric patients have after undergoing spinal fusion surgery.
- Conditions
- Scoliosis; Adolescence, Adolescent Idiopathic Scoliosis, Thoracic Region, Adolescent Idiopathic Scoliosis, Lumbar Region
- Trial name
- NCT06424158
- Testing
- Massage Therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cook Children's Health Care System
Degenerative Lumbar Spinal Stenosis, Degenerative Scoliosis
Paraspinal Muscle Degeneration, Bone Mass and Clinical Outcomes in Patients With Lumbar Degenerative Diseases
This study was a retrospective study. The investigators intended to review the preoperative paraspinal muscle imaging data of patients with lumbar spinal stenosis and degenerative scoliosis treated in hospital, and follow up the…
- Trial name
- NCT05190289
- Testing
- Pre-existing degenerative factors of paraspinal muscles and bone mass
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University Third Hospital
Scoliosis Idiopathic, Scoliosis; Adolescence
Incobotulinumtoxin A and Yoga-like Isometric Exercise in Adolescent Idiopathic Lumbar Scoliosis
The study uses a yoga-like isometric posture and botulinum injections to reduce the curves in adolescent idiopathic lumbar scoliosis.
- Conditions
- Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis; Lumbar Region
- Trial name
- NCT04922983
- Testing
- Botulinum toxin type A, Isometric Yoga-like exercise
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Manhattan Physical Medicine and Rehabilitation, LLP
Low Back Pain
The Effect of Physical Therapy Program and Erector Spina Plane Block in Patients With Degenerative Lumbar Scoliosis
Degenerative (de novo) scoliosis is the result of a long and multifactorial process that occurs through degenerative change in the aging population without a pre-existing spinal deformity.
- Trial name
- NCT06018402
- Testing
- physical therapy, physical therapy + espb
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital