Clinical trials: Scoliosis Patients
Scoliosis Patients
Artificial Intelligence and Scoliosis
The aim of the study to use artificial intelligence technology in assessment of scoliosis degree of severity and to personalize for treatment plan for each pa tient .
- Trial name
- NCT06589583
- Where
- Egypt
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Idiopathic Adolescent Scoliosis, Scoliosis Idiopathic
Effects of Core Stabilization Exercises and Rotation Angular Breathing Exercises Among Idiopathic Scoliosis Patients
This study is a single-blind, two-arm parallel-group randomized controlled trial designed to evaluate the effects of core stabilization exercises combined with rotational angular breathing exercises on adolescents with idiopathic…
- Trial name
- CSE RAB IS (NCT07601893)
- Testing
- Core Stabilization Exercises, Standard Care (in control arm)
- Where
- 2 sites in Pakistan
- Volunteers
- 32 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Pain
Intermittent Epidural Bolus Versus Epidural Infusion for Posterior Spinal Fusion After Adolescent Idiopathic Scoliosis
Patient-controlled Intermittent epidural bolus versus epidural infusion for posterior spinal fusion after adolescent idiopathic scoliosis. Scoliosis surgery is commonly performed in adolescent due to idiopathic scoliosis.
- Trial name
- NCT02669004
- Testing
- Intermittent bolus epidural morphine, continuous epidural morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Inonu University
Scoliosis
Study of 3D Scanning for Adolescent Scoliosis
The investigators aim to validate three-dimensional topographical scanning technology as a tool for evaluation of scoliosis. Through the incorporation of 3D topographical technology in the measurement of deformity, the…
- Trial name
- NCT06035952
- Testing
- 3D topographical scan
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- NSite Medical
Adolescent Idiopathic Scoliosis (AIS), Juvenile Idiopathic Scoliosis
Impact of Spinal Curves on Asymmetric Posture in Idiopathic Scoliosis
Asymmetric postures are often observed in patients with adolescent idiopathic scoliosis (AIS) and are partially associated with instability in sitting and standing positions, as well as with imbalances in gait kinematic…
- Trial name
- ISAPIS (NCT06733623)
- Where
- Italy
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Istituto Scientifico Italiano Colonna Vertebrale
Spinal Muscular Atrophy, Spine Deformity
Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy
The primary objective of the clinical investigation is to demonstrate successful clinical use of the ThecaFlex DRx™ System in delivering nusinersen in subjects with spinal muscular atrophy (SMA).
- Conditions
- Spinal Muscular Atrophy, Spine Deformity, Scoliosis
- Trial name
- PIERRE (NCT05866419)
- Testing
- ThecaFlex DRx System
- Where
- 21 sites in United States, Germany and 3 more
- Volunteers
- 90 people
- Sponsor
- Alcyone Therapeutics, Inc
Genu Varum, Genu Valgus
IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms
While various complex pathologies of the developmental age, such as Infantile Cerebral Palsy or Neuromuscular Diseases, are notoriously considered causes of alteration of locomotor development, it is scarcely known whether…
- Conditions
- Genu Varum, Genu Valgus, Flat Feet, Cavus Foot
- Trial name
- MOTOR-CHILD (NCT05763901)
- Testing
- Clinical tests and motor control evaluation using Inertial Measurement Units
- Where
- Italy
- Volunteers
- 151 people
- Sponsor
- Istituto Ortopedico Rizzoli
Adolescent Idiopathic Scoliosis
Safety and Efficacy Study of Spinal Tethering
This study is an opportunity to gather long term safety and efficacy information from patients who have had their scoliosis treated via anterior vertebral body tethering (VBT).
- Trial name
- NCT02897453
- Testing
- The Spinal Tethering System
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Non-idiopathic Scoliosis
Non-Idiopathic Scoliosis Treated With Tranexamic Acid
Investigation of tranexamic acid (TXA) for reducing perioperative blood loss and transfusion requirement in pediatric patients with secondary scoliosis undergoing posterior spinal fusion.
- Trial name
- NCT01089140
- Testing
- Tranexamic acid 10mg/kg/hr, Tranexamic acid 100 mg/kg/h infusion, Saline solution
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- The Hospital for Sick Children
Adolescent Idiopathic Scoliosis
Treatment of Adolescent Idiopathic Scoliosis Patients Using the Ellipse MAGEC System
The purpose of this study is to collect data on the use of the Ellipse MAGEC System to treat patients with adolescent idiopathic scoliosis (AIS) who have failed external brace therapy.
- Trial name
- NCT01633931
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Ellipse Technologies, Inc.
Leg Length Discrepancy, Scoliosis
Influence of Leg Length Discrepancy on the Spinal Shape and Biomechanics in Functional and Idiopathic Scoliosis Patients
The purposes of this study are to use motion analysis techniques to study the biomechanical interactions between the spine and the lower limbs in scoliosis patients with or without leg length discrepancy (LLD) during activity; to…
- Trial name
- NCT00155545
- Testing
- Motion analysis of patients
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Adolescent Idiopathic Scoliosis
Effect of Compliance Counseling on Brace Success in Patients With Idiopathic Scoliosis
To measure the effectiveness of counseling on brace-wear compliance and curve progression in patients with adolescent idiopathic scoliosis.
- Trial name
- NCT02412137
- Testing
- Counseled cohort
- Volunteers
- 245 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Scoliosis, Scoliosis Kyphosis
Effect of Adult Spinal Deformity Surgery on Functional Reach
Adult spinal deformity (ASD) is a common spinal condition that often impacts an individual's ability to stand and maintain an upright posture.
- Trial name
- NCT06258161
- Testing
- Spinal Fusion, No intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Neuromuscular Diseases, Scoliosis
Effect of the Use of a 3D Scanner Application on a Smartphone to Mold Garchois Orthotic Device in Neuromuscular Diseases Patients With Scoliosis
Neuromuscular scoliosis is the consequence of general hypotonia involved in certain neuromuscular diseases. Thoracic braces are necessary to slow down the deformation.
- Trial name
- GSSCAN (NCT06428864)
- Testing
- Plaster cast, 3D Scanning
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Scoliosis Idiopathic
Protocol of Accelerated Rehabilitation Following Surgical Correction of Adolescent Idiopathic Scoliosis
This study aims to identify whether an accelerated physiotherapy led rehabilitation programme for adolescents undergoing idiopathic scoliosis correction surgery can be delivered safely and effectively post-operatively, and…
- Trial name
- PARIS (NCT03719807)
- Testing
- Rehabilitation protocol, Usual Care
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- The Royal Orthopaedic Hospital NHS Trust
Adolescent Idiopathic Scoliosis, Spinal Fusion
Diaphragmatic Breathing Exercise for Patients Undergoing Arthrodesis Surgery for Adolescent Idiopathic Scoliosis.
After spinal surgery, diaphragmatic breathing exercise can be a low-cost and extremely safe intervention that can be introduced for pain management.
- Conditions
- Adolescent Idiopathic Scoliosis, Spinal Fusion, Pain Management, Exercise
- Trial name
- NCT05311826
- Testing
- STANDARD PHYSIOTHERAPY TREATMENT, EXPERIMENTAL diaphragmatic breathing exercise
- Where
- Italy
- Volunteers
- 79 people
- Sponsor
- Istituto Ortopedico Rizzoli
Adolescent Idiopathic Scoliosis
Does a Pre-operative Exercise Program Improve Post-operative Outcomes for Fusion Patients
A study found that in 1744 patients undergoing fusion surgery for adolescent Idiopathic scoliosis, 12% had back pain remaining after recovering from surgery.
- Trial name
- NCT06076577
- Testing
- Prehabilitation Exercise Group
- Volunteers
- 104 people
- Sponsor
- University of British Columbia
Adolescent Idiopathic Scoliosis
Pedicle Screw Usage in Conventional Fixation Pattern Constructs Compared to Thoracic Hook Constructs in Scoliosis
Scoliosis is a deformity in which there is an abnormal curvature of the spine. Surgery is the main method of correcting this deformity. Rods are attached to the spine to make it strait.
- Trial name
- NCT01581021
- Testing
- Pedicle screws, Laminar Hooks
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Mississippi Medical Center
Mid-Transverse Process Block, Intrathecal Morphine
Analgesic Efficacy of Mid-Transverse Process to Pleura (MTP) Block and Intrathecal Morphine in Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion
The aim of this study is to compare the analgesic efficacy of mid-transverse process to pleura (MTP) block and intrathecal morphine in idiopathic scoliosis patients undergoing posterior spinal fusion surgery.
- Conditions
- Mid-Transverse Process Block, Intrathecal Morphine, Idiopathic Scoliosis, Posterior Spinal Fusion
- Trial name
- NCT06331143
- Testing
- Ultrasound-Guided Mid-Transverse Process to Pleura (MTP) Block, Morphine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Degenerative Disc Disease, Degenerative Spondylolisthesis
Lumbar Interbody Implant Study
The objective of this study is to evaluate the safety and performance of NuVasive interbody implants when used during thoracic and/or lumbar spine surgery as measured by reported complications, radiographic outcomes, and…
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Scoliosis, Spinal Stenosis
- Trial name
- NCT04418830
- Where
- 16 sites in United States
- Volunteers
- 1,050 people
- Sponsor
- NuVasive