Clinical trials: Scoliosis Patients, active
Adolescent Idiopathic Scoliosis (AIS), Juvenile Idiopathic Scoliosis
Impact of Spinal Curves on Asymmetric Posture in Idiopathic Scoliosis
Asymmetric postures are often observed in patients with adolescent idiopathic scoliosis (AIS) and are partially associated with instability in sitting and standing positions, as well as with imbalances in gait kinematic…
- Trial name
- ISAPIS (NCT06733623)
- Where
- Italy
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Istituto Scientifico Italiano Colonna Vertebrale
Degenerative Scoliosis
Scoliosis Treatment: Evaluating Patient Suitability
Degenerative scoliosis can cause back pain, leg pain, difficulty walking, and impaired daily functioning. When spinal fusion is required, choosing the appropriate fusion extent remains challenging.
- Trial name
- STEPS (NCT07891676)
- Volunteers
- 300 people
- Sponsor
- Xuanwu Hospital, Beijing
Adolescent Idiopathic Scoliosis
Brace Monitoring for Adolescent Idiopathic Scoliosis (AIS)
The overall aim of the study is to utilize a novel device and smartphone application in order to improve measurement of patient compliance with at-home bracing for scoliosis as well as create a more accurate assessment of brace…
- Trial name
- NCT03292601
- Testing
- NYRC Brace Scoliosis Monitor
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Columbia University
Adolescent Idiopathic Scoliosis
3D Body Surface Modeling for Scoliosis Monitoring
This is a single center, prospective, non-randomized reproducibility study of the NSite device in patients undergoing evaluation for scoliosis. The NSite device is a pre-market, investigational device.
- Trial name
- NCT05697939
- Testing
- NSite 3D Scanning
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Stanford University
Scoliosis
Biomechanical Study of Lever Positioning Manipulation on Scoliosis
Research background Scoliosis is a common three-dimensional spinal deformity, especially in adolescents. In severe cases, it can lead to thoracic deformation and cardiopulmonary dysfunction.
- Trial name
- NCT07325045
- Testing
- Lever positioning manipulation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons
Evaluation of an Online Peri-operative Health Education Platform for Patients Undergoing Spine Surgery: Ready Set Recover
Chronic back pain is the world's leading cause of disability, with spine surgery being a common yet costly intervention. However, many patients experience suboptimal recovery, with persistent pain and functional limitations…
- Conditions
- Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons, Chronic Low Back Pain, Scoliosis Patients
- Trial name
- NCT07766824
- Testing
- Ready Set Recover
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National University of Natural Medicine
Posterior Spinal Fusion, Idiopathic Scoliosis
Immune Response to PSF in Idiopathic vs Neuromuscular Scoliosis
The objective of this study is to evaluate the immune response to posterior spinal fusion (PSF) in patients with neuromuscular scoliosis, comparing patients with idiopathic scoliosis who undergo the same procedure.
- Conditions
- Posterior Spinal Fusion, Idiopathic Scoliosis, Neuromuscular Scoliosis
- Trial name
- NCT07734467
- Testing
- Serum blood samples for serum biomarkers of immune response
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ambrish Patel
Adolescent Idiopathic Scoliosis (AIS), Exercise (EX)
Effects of Lumbar Traction Combined With 3D Exercise Therapy on Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis (AIS) is a three-dimensional spinal deformity that appears during adolescence without an identifiable underlying cause.
- Trial name
- NCT07448688
- Testing
- Lumbar Mechanical Traction
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Şahide Eda ARTUÇ
Scoliosis; Adolescence, Pain After Surgery
Tegileridine for Postoperative Pain After Adolescent Scoliosis Surgery
The goal of this clinical trial is to see if a new pain medicine called Tegileridine is at least as effective as morphine (the standard treatment) for pain relief after spinal surgery in teenagers with scoliosis.
- Conditions
- Scoliosis; Adolescence, Pain After Surgery, Analgesia, Patient-controlled
- Trial name
- NCT07229495
- Testing
- Tegileridine, morphine
- Where
- 6 sites in China
- Volunteers
- 171 people
- Sponsor
- Peking Union Medical College Hospital
Scoliosis; Adolescence, Adolescent
Quality of Life (HRQoL) of AIS Patients Who Require Bracing or Surgery Using SRS-22 Questionnaire
Adolescent Idiopathic Scoliosis (AIS) is an unexpected curvature of spine at teenage. AIS causes mainly unpleasant appearance, and sometime comes with pain and difficult to locate or move around.
- Conditions
- Scoliosis; Adolescence, Adolescent, Quality of Life, SRS
- Trial name
- QolAISSRS22 (NCT03915106)
- Testing
- Brace, Surgical correction using implants
- Where
- Hong Kong
- Volunteers
- 2,000 people
- Sponsor
- Chinese University of Hong Kong
Duchenne Muscular Dystrophy (DMD)
Research on the Relationship Between Scoliosis, Pain, Quality of Life, and Trunk Muscle Compensation Patterns Among Patients with Duchenne Muscular Dystrophy.
Objective: The objective of this observational study is to evaluate and quantify trunk muscle compensatory movement patterns in patients with Duchenne Muscular Dystrophy (DMD) using computer vision technology.
- Trial name
- NCT06755138
- Testing
- Observational Assessment
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Postural Alignment, Idiopathic Adolescent Scoliosis
Artificial Intelligence-Based Postural Feedback for Scoliosis
Due to advancements in technology, Posture-Analyzing and Virtual Reconstructing (PAViR) systems were developed. They used Red-Green-Blue-Depth camera sensors and artificial intelligence to evaluate human posture alignment, muscle…
- Trial name
- NCT07669428
- Testing
- Postural feedback, Physical therapy for scoliosis
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Adolescent Idiopathic Scoliosis (AIS)
Evaluation of a Novel Semi-Rigid Brace for Adolescent Idiopathic Scoliosis
Introduction: Spinal bracing remains the gold standard for conservative management of adolescent idiopathic scoliosis (AIS). However, poor adherence often limits treatment efficacy.
- Trial name
- NCT07040150
- Testing
- Spinal bracing
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Nippon Sigmax co., ltd.
Idiopathic Adolescent Scoliosis, Scoliosis Idiopathic
Effects of Core Stabilization Exercises and Rotation Angular Breathing Exercises Among Idiopathic Scoliosis Patients
This study is a single-blind, two-arm parallel-group randomized controlled trial designed to evaluate the effects of core stabilization exercises combined with rotational angular breathing exercises on adolescents with idiopathic…
- Trial name
- CSE RAB IS (NCT07601893)
- Testing
- Core Stabilization Exercises, Standard Care (in control arm)
- Where
- 2 sites in Pakistan
- Volunteers
- 32 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis (AIS)
Real-World Effectiveness of Conservative Treatment in Idiopathic Scoliosis
This retrospective observational study aims to assess the real-world effectiveness of conservative treatment (bracing and specific exercises) in patients with idiopathic scoliosis treated with an Evidence-Based Personalised…
- Conditions
- Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis (AIS), Juvenile Idiopathic Scoliosis
- Trial name
- NCT07873554
- Testing
- Brace, Specific exercises (SEAS)
- Where
- Italy
- Volunteers
- 30,000 people
- Sponsor
- Istituto Scientifico Italiano Colonna Vertebrale
Scoliosis, Scoliosis Kyphosis
Effect of Adult Spinal Deformity Surgery on Functional Reach
Adult spinal deformity (ASD) is a common spinal condition that often impacts an individual's ability to stand and maintain an upright posture.
- Trial name
- NCT06258161
- Testing
- Spinal Fusion, No intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Adolescent Idiopathic Scoliosis (AIS)
Small Study Comparing Two Pain Medicines in Teenagers for Pain Control After Scoliosis Corrective Surgery.
The goal of this clinical trial is to evaluate whether adding low-dose ketamine to PCA morphine reduces opioid requirements after posterior spinal fusion surgery in adolescent idiopathic scoliosis patients.
- Trial name
- KetaMorph (NCT07452705)
- Testing
- Ketamine-Morphine PCA, Morphine (Intravenous patient-controlled analgesia)
- Where
- Malaysia
- Volunteers
- 114 people
- Sponsor
- University of Malaya
Adolescent Idiopathic Scoliosis (AIS), Mental Health
Psychological Assessment of Scoliosis Patients Undergoing Surgical Management
Working in partnership with Montefiore-Einstein's Department of Translational Psychiatry, the investigators have designed a prospective randomized clinical trial (2:1) study for 45 Adolescent Idiopathic Scoliosis (AIS) patients…
- Trial name
- PASS (NCT05774002)
- Testing
- Aims to Decrease Anxiety and Pain Treatment (ADAPT)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Montefiore Medical Center
Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute
The Use of a Comfort Tote to Improve Recovery in Pediatric and Adolescent Patients After Surgery
The goal of this clinical trial is to learn if the use of Comfort Tote can treat pain and anxiety in adolescents with idiopathic scoliosis undergoing posterior spinal fusion. The study aims to answer two questions: 1.
- Conditions
- Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute, Postoperative Nausea and Vomiting, Anxiety
- Trial name
- NCT07632833
- Testing
- The Therapeutic Comfort Tote, The Modified Comfort Tote
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Adult Spinal Deformity, Scoliosis
Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients
Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients
- Conditions
- Adult Spinal Deformity, Scoliosis, Kyphosis
- Trial name
- NCT04888104
- Testing
- Index or revision spine surgery for complex adult spinal deformity
- Where
- 9 sites in United States
- Volunteers
- 225 people
- Sponsor
- International Spine Study Group Foundation