Clinical trials: Scoring Systems
Knee Arthroplasty, Total
iTotal Pilot Study of ConforMIS Custom Total Knee Implant
To compare the outcomes of patients receiving the ConforMIS custom total knee implant to the outcomes of patients who receiving an off-the-shelf total knee implant.
- Trial name
- NCT02186587
- Testing
- ConforMIS custom total knee
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Missouri-Columbia
Diagnosis of Acute Appendicitis in Children
Urinary 5-HIAA for Diagnosis of Acute Appendicitis in Children, Does it Help?
it is randomized control study. two groups of children (n=191) were divided into two groups A and B. Group A included children subjected to the classical protocol of diagnosis of acute appendicitis.
- Trial name
- NCT04527263
- Testing
- measurement of urinary 5-HIAA
- Where
- Egypt
- Volunteers
- 191 people
- Sponsor
- Tanta University
SLE - Systemic Lupus Erythematosus
Does Belimumab Modify the Natural History of SLE? A Propensity Score-matched, Real-world Study
This will be a combined retrospective and prospective cohort study, that will evaluate the incidence of de novo Systemic Lupus Erythematosus major organ manifestations (defined as BILAG A flares) in patients receiving belimumab…
- Trial name
- NCT07056621
- Where
- Greece
- Volunteers
- 684 people
- Sponsor
- Biomedical Research Foundation, Academy of Athens
Lung Cancer
Pneumonitis After Radiotherapy for Lung Cancer
Major goals of radiotherapy include local disease control and improvement of the patients' prognoses. One possible side effect of radiotherapy for lung cancer is radiation pneumonitis.
- Trial name
- PARALUC (NCT04335409)
- Testing
- Questionnaire, Mobile Application
- Where
- Germany
- Volunteers
- 57 people
- Sponsor
- University Hospital Schleswig-Holstein
Postoperative Complications, Other Complications of Other Bariatric Procedure
Edmonton Obesity Staging System: Post-operative Outcome and 30-day Mortality
The Edmonton Obesity Staging System (EOSS) is a more comprehensive measure of obesity-related diseases and predictor of mortality than BMI or waist circumference.
- Trial name
- NCT02607267
- Testing
- LSG and LRYGB
- Where
- Germany
- Volunteers
- 534 people
- Sponsor
- Sana Klinikum Offenbach
Bleeding
Potassium-competitive Acid Blocker Versus Double Dose Proton Pump Inhibitors in High High-risk Peptic Ulcer Bleeding
This randomized clinical trial will enroll patients at National Cheng Kung University Hospital who have upper gastrointestinal ulcer bleeding, have undergone endoscopic hemostasis, and have a Rockall score of 6 or higher.
- Trial name
- NCT07772700
- Testing
- Vonoprazon, Esomeprazole
- Volunteers
- 108 people
- Sponsor
- National Cheng-Kung University Hospital
Meningitis
Validation of a Predictive Rule for the Diagnosis of Viral Meningitis in Adult Emergency Departments
Meningitis is the development of an inflammatory reaction in the meningeal space, most often of infectious origin. Many pathogens can cause meningitis, the severity of which varies greatly.
- Trial name
- Adult-BMS (NCT05062642)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier le Mans
Transient Ischemic Attack (TIA)
Canadian TIA Score Versus ABCD2 Score in Risk Stratification of Transient Ischemic Attack (TIA)
This study aims to evaluate the superiority of a clinical score (Canadian TIA score) compared to the currently more widely used score in clinical practice (ABCD2 score) in stratifying the risk of stroke or carotid…
- Trial name
- NCT06718075
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Renal Cell Carcinoma
Multimodal Recurrence Scoring System for Stratifying Stage III Clear Cell Renal Cell Carcinoma of Receiving Adjuvant Treatment
Whether patients with stage III clear cell renal cell carcinoma (ccRCC) should receive adjuvant targeted therapy or not is still on debate.
- Trial name
- NCT06032728
- Testing
- Sunitinib
- Volunteers
- 488 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Ischemic Stroke
Αdherence and Persistence to Oral Anticoagulation in ΑF Patients With Previous Ischemic Stroke
The aims of this project are to: 1. investigate the adherence and persistence to anticoagulation (and in specific, to VKAs and NOACs) in AF patients with previous ischemic stroke; 2.
- Trial name
- ADHERE-OAC (NCT03463421)
- Where
- 2 sites in Finland, Greece
- Volunteers
- 1,200 people
- Sponsor
- University of Thessaly
Stroke
A Diagnosis Study of a New Prehospital Strokeidentification Test, the PreHospitalt Ambulans Stroke Test (PreHAST), to be Used to Triage Patients With Suspected Stroke
The aim of the Pre-HAST study is to improve identification and triage of patients with suspected stroke in order to get the right patient to the right level of care as fast as possible.
- Trial name
- Pre-HAST (NCT04555499)
- Testing
- Standardized neurological examination
- Where
- 2 sites in Sweden
- Volunteers
- 78 people
- Sponsor
- Karolinska Institutet
Rectal Cancer, Quality of Life
Quality of Life After Transanal Total Mesorectal Excision Compared to Traditional Total Mesorectal Excision
The improvement in prognosis of rectal cancer through modern therapy modalities rises questions regarding quality of life (QoL) and functional outcomes.
- Conditions
- Rectal Cancer, Quality of Life, Functional Outcome, Surgery
- Trial name
- NCT06505863
- Testing
- Transanal total mesorectal excision, Abdominal total mesorectal excision
- Where
- Switzerland
- Volunteers
- 249 people
- Sponsor
- Cantonal Hospital of St. Gallen
Chronic Spontaneous Urticaria
Long-term Efficacy and Safety Extension (LTE) Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria
The purpose of this extension study is to collect long-term efficacy and safety data on barzolvolimab in adult participants with Chronic Spontaneous Urticaria (CSU) who completed the treatment and follow-up periods of the Phase 3…
- Trial name
- NCT07256392
- Testing
- barzolvolimab, Standard of Care
- Where
- 201 sites in United States, Argentina and 28 more
- Volunteers
- 1,370 people
- Sponsor
- Celldex Therapeutics
Multiple Sclerosis
Genes and Environment in Multiple Sclerosis
The purpose of the research study is to identify the genetic, environmental and immune profiles that may increase a person's risk of developing multiple sclerosis (MS).
- Trial name
- GEMS (NCT01353547)
- Where
- 5 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Abdominal Cancer, Cancer Pain
Permanent Celiac Plexus Block: Comparison of Pain Score in Unilateral and Bilateral Posterior Percutaneous Approach
The goal of this prospective, interventional, non-randomized study was to compare pain score in unilateral and bilateral posterior percutaneous neurolytic celiac plexus block (NCPB) in upper abdominal cancer patients.
- Conditions
- Abdominal Cancer, Cancer Pain, Cancer of Pancreas
- Trial name
- NCT06316908
- Testing
- Unilateral Neurolytic Celiac Plexus Block with Absolute Alcohol, Bilateral Neurolytic Celiac Plexus Block with Absolute Alcohol
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Myelodysplastic Syndromes
A Novel Conditioning Regimen for Myelodysplastic Syndrome With Moderate High IPSS-M Score
Figure out the Efficacy and Safety of Azacitidine Combined with BUCY2 Conditioning Regimen Before Allogeneic Hematopoietic Stem Cell Transplantation for Myelodysplastic Syndrome with Moderate High IPSS-M Score
- Trial name
- NCT06279338
- Testing
- Azacitidine Injection
- Volunteers
- 40 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Low Anterior Resection Syndrome
Translation of the International Consensus Definition of LARS Into a Bowl Dysfunction Severity Scoring Tool (New LARS Score)
The purpose of this study is to develop a new severity scoring tool for Low Anterior Resection Syndrome (LARS) drawing on the international consensus criteria for LARS as well as opinions of patients with lived-experience of LARS.
- Trial name
- NCT05605600
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Cardiff and Vale University Health Board
Gastroesophageal Reflux
Non-interventional Study to Evaluate the Change in Symptoms Scores and Treatment Response After 4 Weeks of Proton-Pump Inhibitors (PPI) Treatment
The primary objective of the study is to describe the change in GerdQ sum scores, after a 4-week period of systematic treatment with PPIs(using GerdQ questionnaire).
- Trial name
- NCT01103804
- Where
- 19 sites in Romania
- Volunteers
- 952 people
- Sponsor
- AstraZeneca
Enlargement of Tonsil or Adenoid
Bioclinical Profile of Adenotonsillar Hypertrophy in the Pediatric Population
Adenotonsillar hypertrophy is the principal cause of obstructive sleep apnea of childhood, yet little is known with regard to its pathophysiologic and molecular mechanisms.
- Trial name
- NCT03541434
- Testing
- Complete Blood Count, Tympanometry, Tonsillectomy and/or adenoidectomy
- Where
- 2 sites in Greece
- Volunteers
- 134 people
- Sponsor
- University of Patras
Schizophrenia Patients, Neuroinflammation
Effectiveness of Ashwagandha in Schizophrenia Patients on Risperidone
This study aims to evaluate the effectiveness of Ashwagandha (Withania somnifera) extract as an adjuvant therapy in patients with schizophrenia who are receiving risperidone.
- Trial name
- WSE-SCZ (NCT07575516)
- Testing
- Risperidone 4mg/day, Ashwagandha
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Hasanuddin University