Clinical trials: Screening Colonoscopies
Colonoscopy, Colorectal Cancer Screening
Triton 1.5 Robotic System for Diagnostic Colonoscopy
This study is a prospective, single-arm, non-randomized, single-site study, focused on evaluating the safety and efficacy of the Triton 1.5 System in diagnostic and basic therapeutic colonoscopy.
- Trial name
- CARE II (NCT07606963)
- Testing
- Diagnostic Test: Diagnostic Colonoscopy
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Colon Cancer, Colon Sessile Serrated Adenoma/Polyp
Narrow Band Imaging Versus White Light for Colonoscopy Serrate Lesions Detection
Colorectal cancer (CRC) is a leading cause of cancer death and its' incidence is rising in most European countries. Colonoscopy has been shown to reduce CRC incidence, however its effectiveness depends on the sensitivity to…
- Trial name
- NCT02876133
- Testing
- narrow band imaging withdrawal, white light withdrawal
- Where
- 3 sites in Portugal
- Volunteers
- 987 people, healthy volunteers welcome
- Sponsor
- Hospital Beatriz Ângelo
Polyps, Neoplasia
Comparison Between HD+ Endoscopy and Standard Videoendoscopy in Screening Colonoscopy
Colonoscopy is the accepted gold standard for screening of colorectal cancer. However, small and flat neoplastic lesions might be overlooked with standard video endoscopes.
- Trial name
- NCT00792649
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Colorectal Cancer, Advanced Adenocarcinoma
A Multicenter Clinical Trial of Stool-based DNA Testing for Early Detection of Colon Cancer in China
According to data from Global Cancer Statistics 2018, colorectal cancer (CRC) ranks second in incidence and fifth in mortality among all cancers in China.
- Conditions
- Colorectal Cancer, Advanced Adenocarcinoma, Hyperplastic Polyp, Colorectal Neoplasms
- Trial name
- NCT04722055
- Testing
- Multigene Methylation Detection Kit
- Where
- China
- Volunteers
- 1,273 people, healthy volunteers welcome
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
Narrow Band Imaging
Comparison of ADR Using NBI Versus HD White Light Colonoscopy in Screening and Surveillance Colonoscopies
The aim of this study is to compare ADR using HD-NBI or HD-WLE during screening and surveillance colonoscopies.
- Trial name
- NCT03081975
- Testing
- HD white light or NBI
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jena University Hospital
Colorectal Cancer
Effectiveness of Fecal Immunnochemical Test and Colonoscopy Screening in Hong Kong
Colorectal neoplasm in Asia is now increasingly common and is rising in an alarming manner in Hong Kong. Population-based screening for colorectal cancer (CRC) should be implemented.
- Trial name
- NCT03597204
- Testing
- Fecal immunochemical test (FIT), Colonoscopy
- Where
- Hong Kong
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colonoscopy, Looping
Experimental Device to Improve Colonoscopy
This study will test the use of a new device called a segmental stiffening wire (SSW) in colonoscopy to correct a problem called looping.
- Conditions
- Colonoscopy, Looping, Prevent Looping, Colon Cancer Screening
- Trial name
- NCT00719641
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Adenomatous Polyps
Does Cap Assisted Colonoscopy Improve Detection of Adenomatous Polyps? (CAP Trial)
Effectiveness of screening colonoscopy in cancer prevention relies on the detection and removal of adenomatous polyps. However, a substantial rate of adenomas is missed during a colonoscopy.
- Trial name
- CAP (NCT01935180)
- Testing
- Colonoscopy Cap
- Where
- 2 sites in United States
- Volunteers
- 1,148 people, healthy volunteers welcome
- Sponsor
- White River Junction Veterans Affairs Medical Center
HELICOBACTER PYLORI INFECTIONS, Intestinal Metaplasia
Endoscopic Screening of Asymptomatic Patients for Helicobacter Pylori, Intestinal Metaplasia, and Barrett's Mucosa During Screening Colonoscopy
The goal of this observational study is to learn how common Helicobacter pylori (H. pylori) infection is in adults without stomach or upper gastrointestinal symptoms who are having a preventive screening colonoscopy.
- Conditions
- HELICOBACTER PYLORI INFECTIONS, Intestinal Metaplasia, Barett's Esophagus
- Trial name
- G-SCOGE (NCT07346521)
- Where
- Austria
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sigmund Freud PrivatUniversitat
Colon Adenoma, Colorectal Cancer
Clinical Efficacy Evaluation of a Computer-aided Colonoscopy as Compared With the Standard Colonoscopy.
Colonoscopy is clinically used as the gold standard for detection of colorectal cancer (CRC) and removal of adenomatous polyps of the colon and rectum.
- Trial name
- NCT05240625
- Testing
- "aetherAI" Computer-aided Polyp Detection (CADe) Systems for Colonoscopy, Standard colonoscopy
- Where
- Taiwan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Screening of Colonic Polyps
Techniques to Enhance Patient Comfort in Sedation-risk Free Colonoscopy
Hypotheses 1. Loading the sigmoid colon with warm water and warm water irrigation for dealing with spasm (Study Treatment) will significantly reduce the proportion of patients complaining of abdominal discomfort compared with no…
- Trial name
- NCT01076907
- Testing
- Warm water, Control
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- VA Greater Los Angeles Healthcare System
Colon Polyp
Collecting Recorded Videos of Colonoscopy Screening Tests
The study shall mainly help to better evaluate the performance the APDS device and secondly it may help to assess the potential of the future alpha version of the device to be a useful and effective for the detection of colon…
- Trial name
- NCT03891290
- Testing
- Collecting recorded videos of Colonoscopy screening tests of the general population
- Where
- Israel
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Magentiq Eye LTD
Colon Cancer, Rectal Cancer
Validation of Colon Biomarkers for the Early Detection of Colorectal Adenocarcinoma
The investigators are undertaking a multi-center, 13000 subject validation study of several biomarkers for early detection of colon cancer.
- Trial name
- GLNE010 (NCT01511653)
- Where
- 9 sites in United States, Canada and 1 more
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Colon Cancer Screening
Randomized Control Trial Comparing the Incidence of Loop Formation in Colonoscopy Techniques
A colonoscopy is a common procedure used to check for problems in the colon, such as disease or other health issues. Although it's widely used, one challenge is that the flexible tube used in the procedure (called a colonoscope)…
- Trial name
- NCT07245173
- Testing
- colonoscopy
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Colorectal Cancer
Telemark Polyp Study, a Trial on Colonoscopy Screening
Colonoscopy screening to reduce mortality and incidence of colorectal cancer (CRC) has been implemented in many western countries. The estimated effect is based on case-control and observational studies.
- Trial name
- TPS (NCT01014039)
- Testing
- Flexible Sigmoidoscopy Screening arm
- Where
- Norway
- Volunteers
- 1,433 people, healthy volunteers welcome
- Sponsor
- Norwegian Department of Health and Social Affairs
Colonic Polyp, Colon Cancer
Improving Outpatient Colonoscopy Bowel Prep With the Orton Score
Colonoscopy is a common endoscopic procedure which the UVA Gastroenterology \& Hepatology department performs on a daily basis for both screening/surveillance and diagnostic/therapeutic intent.
- Trial name
- NCT04093557
- Testing
- Orton Score, Typical Standard of Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia
Breast Cancer, Colorectal Cancer
Population-Based Patient-Centric Care: Comprehensive Preventive Cancer Screening Using Health IT
Although there is considerable evidence that current health IT can improve certain elements of care, the most effective and efficient implementation of health IT systems for primary care population management are not currently…
- Conditions
- Breast Cancer, Colorectal Cancer, Cervical Cancer
- Trial name
- TopCare (NCT01372527)
- Testing
- TopCare: Use of provider knowledge vs. automated system
- Where
- United States
- Volunteers
- 103,870 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Screening Colonoscopy, Surveillance Colonoscopy
Evaluation of Proposed EZ2go Complete Bowel Cleansing System
This study aims to provide safety and efficacy data comparable to available over-the-counter bowel preparations prior to colonoscopy.
- Conditions
- Screening Colonoscopy, Surveillance Colonoscopy, Colonoscopy
- Trial name
- NCT01838408
- Testing
- Ez2go Complete, LoSo Prep
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Borland-Groover Clinic
Bowel Preparation, WhatsApp Messenger
WhatsApp Reminder on Bowel Preparation Level
It is estimated that there are about 1.4 million patients with colorectal cancer (CRC) worldwide, with a rising trend in CRC incidence in many Asian Pacific countries.
- Conditions
- Bowel Preparation, WhatsApp Messenger, Colonoscopy
- Trial name
- NCT03209739
- Testing
- WhatsApp reminder
- Where
- Hong Kong
- Volunteers
- 666 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Cancer, Colorectal Adenomas
Water Exchange Versus Carbon Dioxide for Colonoscopy
Colonoscopy is commonly used in screening for colorectal cancer. A refined technique of colonoscopy involving the use of water as the sole modality to aid colonoscope insertion, water exchange, has been described in recent…
- Conditions
- Colorectal Cancer, Colorectal Adenomas, Colorectal Polyps, Pain
- Trial name
- NCT01633333
- Testing
- Water exchange colonoscopy, Carbon dioxide insufflation
- Where
- 3 sites in Norway, Poland
- Volunteers
- 473 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF