Clinical trials: Screening Colonoscopy
Adenoma Detection Rate, Colonoscopy
The Factors Affecting ADR of Screening Colonoscopy
The purpose of this study is to assess the impact of multilevel factors on the quality of screening colonoscopy, reflected mainly by adenoma detection rate (ADR).
- Trial name
- NCT04397120
- Where
- China
- Volunteers
- 13,495 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Adenoma Detection Rate Improvement in Screening Colonoscopy
Endoscopic Size Assessment of Advanced Adenomatous Polyps
The investigators are retrospectively comparing detection rates of adenomatous polyps, advanced adenomas, and size assessment of the polyps among Rush University Medical Center endoscopists.
- Trial name
- NCT02193646
- Where
- United States
- Volunteers
- 1,930 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Colorectal Adenoma
Colorectal Neoplasia Screening w Colonoscopy in Asymptomatic Women at Regional Navy/Army Medical Ctrs: The CONCeRN Trial
The CONCeRN Trial is a multi-center study of asymptomatic women between the ages of 40 and 75 referred to regional military medical centers for routine colorectal screening.
- Trial name
- NCT00339950
- Where
- 3 sites in United States
- Volunteers
- 937 people
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer Screening
Bowel Preparation in Colonoscopy: Lactulose vs Polyethyleneglycol, Randomized Double-blind Comparative Clinical Trial, Multicenter Study.
The goal of this clinical trial it is to bowel the instestinal preparation with lactulose vs poliethylenglicol as better agent to have a quality colonoscopy and demostrate that lactulose is most efective, has a good tolerance and…
- Trial name
- NCT06666556
- Testing
- Bowel preparation before colonoscopy
- Where
- 3 sites in Mexico
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- Hospital Civil de Guadalajara
Colorectal Cancer, Premalignant Colon Lesions
A Mobile Application to Improve the Quality of Colonoscopy in Colorectal Cancer Screening Program (PrepColon APP)
Colonoscopy is the gold standard for the diagnosis and resection of preneoplastic lesions, allowing the prevention of colon cancer.
- Trial name
- PREPCOLON (NCT06314022)
- Testing
- Mobile application for colonoscopy preparation instructions
- Where
- 2 sites in Spain
- Volunteers
- 470 people
- Sponsor
- Hospital del Rio Hortega
Colorectal Cancer
Colonoscopy Outreach for Rural Communities Aim 2
This study aims to test the effectiveness of a remotely-delivered patient navigation program for increasing colonoscopy completion for colorectal cancer screening, among rural populations.
- Trial name
- NCT05453630
- Testing
- Patient Navigation, Usual Care Control
- Where
- United States
- Volunteers
- 527 people, healthy volunteers welcome
- Sponsor
- University of Washington
Colonic Irrigation
Feasibility and Effectiveness of Colonic Irrigation
This study will allow investigators to determine whether colonic irrigation may allow for a non-oral, same-day alternative to traditional oral bowel prep regimens.
- Trial name
- NCT02826967
- Testing
- Colonic Irrigation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- NYU Langone Health
Colorectal Cancer, Polyp of Colon
EAGLE Trial CADDIE Artificial Intelligence Endoscopy
The EAGLE study is a prospective randomized controlled multicenter parallel design trial, for the assessment of clinical performance of the CADDIE device and to confirm that the device performs as expected.
- Conditions
- Colorectal Cancer, Polyp of Colon, Adenoma Colon
- Trial name
- EAGLE (NCT05730192)
- Testing
- Colonoscopy with CADDIE, Standard Colonoscopy
- Where
- 8 sites in Germany, Italy and 2 more
- Volunteers
- 985 people
- Sponsor
- Odin Medical
Colorectal Cancer, Colorectal Neoplasm
Colorectal Cancer Screening in Average-risk Population: Immunochemical Fecal Occult Blood Testing Versus Colonoscopy
Aims: 1. To compare the efficacy of biennial immunochemical fecal occult blood test (iFOBT) versus colonoscopy every 10 years for the reduction of colorectal cancer-related mortality at 10 years in average-risk population. 2.
- Trial name
- NCT00906997
- Testing
- Immunochemical fecal occult blood test, Colonoscopy
- Where
- 8 sites in Spain
- Volunteers
- 55,498 people
- Sponsor
- Hospital Clinic of Barcelona
Colorectal Cancer
Head to Head Study Epi proColon and FIT
The study aims to show non-inferiority in the clinical performance of the investigational assay, Epi proColon, to FIT using matched blood and stool specimens from screening-guideline eligible subjects.
- Trial name
- NCT01580540
- Where
- 70 sites in United States, Puerto Rico
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Epigenomics, Inc
Breast Cancer Screening, Colon Cancer Screening
Bundled Cancer Screening and Genetic Services Navigation
The goal of this study is to test bundled familial cancer risk assessment + multicancer (colorectal + breast) vs. single (breast) cancer navigation, using a wait list control for colorectal cancer screening referral and…
- Conditions
- Breast Cancer Screening, Colon Cancer Screening, Genetics Predisposition
- Trial name
- NCT07228000
- Testing
- Breast cancer screening navigation, Multicancer screening navigation, Usual care genetics referral
- Where
- 2 sites in United States
- Volunteers
- 820 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Colorectal Cancer
Two Low Volume Regimens for Colorectal Cancer Screening Colonoscopy
Colorectal cancer is the first neoplasm most commonly diagnosed in both sexes and the second leading cause of cancer death in Spain.
- Trial name
- LOWOL (NCT04297423)
- Testing
- Plenvu
- Where
- Spain
- Volunteers
- 1,002 people
- Sponsor
- Hospital Clinic of Barcelona
Colo-rectal Cancer, Colonic Neoplasms
Effect of Adding Simethicone to Split-dose Polyethylene Glycol for Bowel Preparation in a Screening Colonoscopy Setting
Colonoscopy is currently accepted as the gold standard in screening, surveillance and prevention for colorectal cancer (CRC), and therefore, its quality is a major priority.
- Trial name
- NCT03816774
- Testing
- PEG split-dose and simethicone
- Where
- Portugal
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- Portuguese Oncology Institute, Coimbra
Colon Neoplasm
Correlation Between ADR of Screening and All Colonoscopies
The aim of the study is to compare ADR for colonoscopies from various indications and to find correlations between ADR of screening and all examinations.
- Trial name
- NCT03730441
- Testing
- Colonoscopy
- Where
- Czechia
- Volunteers
- 6,925 people
- Sponsor
- Hospital Frydek-Mistek
Colorectal Neoplasms, Colon Polyp
Computer-aided Detection During Screening Colonoscopy (Experts)
Evaluation of the colonic mucosa with a high definition colonoscope (EPKi7010 video processor). The endoscopy images will be seen on a 27inch, flat-panel, high-definition LCD monitor (Radiance™ ultraSC-WU27-G1520 model) only by…
- Conditions
- Colorectal Neoplasms, Colon Polyp, Colon Adenoma
- Trial name
- NCT04915833
- Testing
- Standard high-definition colonoscopy, Colonoscopy with real-time AI assisted automated polyp detection
- Where
- Ecuador
- Volunteers
- 209 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Colorectal Polyps
Virtual Colonoscopy (VC) for Primary Colorectal Screening
This study involves a primary VC screening for colorectal polyps. The research hypothesis is that VC screening, including surveillance of sub-cm polyps, is a safe and effective approach.
- Trial name
- NCT00204867
- Testing
- CTC surveillance
- Where
- United States
- Volunteers
- 272 people
- Sponsor
- University of Wisconsin, Madison
Colon Polyp
Collecting Recorded Videos of Colonoscopy
The study shall mainly help to better evaluate the performance the APDS device and secondly it may help to assess the potential of the future alpha version of the device to be a useful and effective for the detection of colon…
- Trial name
- NCT03891251
- Testing
- Collecting recorded videos of Colonoscopy screening tests
- Where
- Israel
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Magentiq Eye LTD
Adenoma Colon
Detection of Adenomas in Screening Colonoscopy
The Endocuff study aims to show an increase of the number of detected adenomas in screening colonoscopies when a endocuff vision (Arc Medical Design Ldt Leeds England) is used.
- Trial name
- NCT04651062
- Testing
- endocuff, no endocuff
- Where
- Denmark
- Volunteers
- 1,178 people, healthy volunteers welcome
- Sponsor
- Herning Hospital
Colonoscopy
A Trial Comparing Split-Dose Miralax With Amitiza Pretreatment Versus Dulcolax Pretreatment Versus Golytely for Bowel Cleansing Prior to Colonoscopy
Miralax (PEG 3350) has been shown to be a safe and uncomplicated bowel preparation prior to colonoscopy in pediatric populations.
- Trial name
- NCT00953017
- Testing
- Miralax (PEG 3350), Amitiza (Lubiprostone), Dulcolax (Bisacodyl)
- Where
- United States
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Polyp Resection Adequacy
Colorectal Polyp Resection Adequacy
The purpose of this study is to determine the best way to ensure that polyps are completely removed by evaluating the borders of the removed polyp.
- Trial name
- NCT02217085
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center