Clinical trials: Seasonal Allergic Rhinitis
Rhinitis, Allergic, Seasonal, Hay Fever
Study Using the Environmental Exposure Unit (EEU) to Assess the Onset of Action of Ciclesonide, Applied as a Nasal Spray in the Treatment of Seasonal Allergic Rhinitis (BY9010/M1-407)
The primary objective of this placebo-controlled EEU study is to determine the time to onset of action of ciclesonide, applied as a nasal spray (200 mg, once daily) in patients with SAR.
- Trial name
- NCT00659503
- Testing
- Ciclesonide
- Where
- Canada
- Volunteers
- 420 people
- Sponsor
- AstraZeneca
Seasonal Allergic Rhinitis, Allergic Conjunctivitis
Montelukast as a Controller of Atopic Syndrome
The purpose of the study is to find out if montelukast can be used to treat the various symptoms of allergic syndrome.
- Conditions
- Seasonal Allergic Rhinitis, Allergic Conjunctivitis, Atopic Eczema, Asthma
- Trial name
- MONTAS (NCT00559546)
- Testing
- montelukast
- Where
- Finland
- Volunteers
- 61 people
- Sponsor
- University of Helsinki
Seasonal Allergic Rhinitis, Asthma
Safety Study of Ragweed-SPIRE in Subjects With Ragweed Allergies and Asthma
The purpose of this study is to determine whether it is safe to administer Ragweed-SPIRE to subjects suffering from both ragweed allergy and asthma.
- Trial name
- NCT02061670
- Testing
- Ragweed-SPIRE
- Where
- 5 sites in Canada
- Volunteers
- 55 people
- Sponsor
- Circassia Limited
Allergic Rhinitis Due to Weed Pollen, Montelukast
Early Intervention in Allergic Patients
As many as 250 million people suffer from allergic rhinitis in China, which has a large population, early use of drugs may help better control the symptoms.This study aimed to investigate the effects of early interventional…
- Trial name
- NCT05040828
- Testing
- Start taking Montelukast Sodium Tablets 10mg quaque die orally two weeks before peak pollen count., Montelukast Sodium Tablets 10mg quaque die orally was administered after peak pollen count., No oral drug therapy throughout the pollen period
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Beijing Tongren Hospital
Seasonal Allergic Rhinitis
Monocenter 6-period Study in Patients With Seasonal Allergic Rhinitis to Birch Pollen to Establish a Challenge Model With Natural Birch Pollen in an Environmental Challenge Chamber (ECC)
This clinical validation study is aimed at establishing a birch pollen challenge in the Fraunhofer ECC in patients allergic to birch pollen.
- Trial name
- NCT01983865
- Testing
- Exposure to birch pollen
- Volunteers
- 18 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Atopic Dermatitis, Allergy Pollen
Study to Assess the Effect of "Eucerin AtopiControl" on Dermal Symptoms in Patients With Atopic Dermatitis
The objective of this study is to assess the effect of 'Eucerin AtopiControl LOTION' and 'Eucerin AtopiControl facial cream' on dermal symptoms in patients with Atopic Dermatitis (AD) after two 4 h challenges with grass pollen on…
- Trial name
- NCT03315611
- Testing
- 'Eucerin AtopiControl Lotion' (for the body), Allergen challenge chamber
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Seasonal Allergic Rhinitis
A Clinical Study on the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of SHR-1819 Injection in Patients With Seasonal Allergic Rhinitis
This is a trial to evaluate the safety and efficacy of SHR-1819 injection in the treatment of patients with seasonal allergic rhinitis.
- Trial name
- NCT07091357
- Testing
- SHR-1819 Injection
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Guangdong Hengrui Pharmaceutical Co., Ltd
Birch Pollen Allergy, Healthy Control Subjects
Effect of the Nasal Provocation on the Breathing Style
The purpose of this study is to find out how the provocation of the nose changes breathing style (specifically, frequency and tidal volume changes)
- Trial name
- NCT02146300
- Testing
- 1. session birch pollen nasal exposure 2. session xylometazoline nasal exposure
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Seasonal Allergic Rhinitis
Placebo-Controlled Study of Mometasone Furoate Nasal Spray (MFNS) 200 mcg QD in the Treatment of Seasonal Allergic Rhinitis (Study P05106)(COMPLETED)
This study is designed to assess the effectiveness of mometasone furoate nasal spray (MFNS) once daily compared with placebo in subjects with seasonal allergic rhinitis (SAR) in reducing the total symptom score.
- Trial name
- NCT00468312
- Testing
- Mometasone furoate nasal spray
- Volunteers
- 429 people
- Sponsor
- Organon and Co
Rhinitis, Allergic, Seasonal, Seasonal Allergic Rhinitis
Trial With Rhinitic Patients Taking GSK256066 Versus Placebo In A Pollen Challenge Chamber
This study is in patients with seasonal allergic rhinitis(SAR)and will compare the effect versus placebo of repeat doses of intranasal GSK256066 using the Vienna Challenge Chamber.
- Trial name
- NCT00377728
- Testing
- GSK256066
- Where
- Austria
- Volunteers
- 44 people
- Sponsor
- GlaxoSmithKline
Seasonal Allergic Rhinitis
A Study to Assess the Efficacy and Safety of PG-011 Nasal Spray in Adults With Moderate to Severe Seasonal Allergic Rhinitis
The study is a multicenter, randomized, double-blind, placebo-controlled seamless and adaptive-designed phase IIb/III study encompassing a phase IIb and a phase III component.
- Trial name
- Pumecitinib (NCT06837233)
- Testing
- Pumecitinib Nasal Spray 0.3%, Pumecitinib Nasal Spray 0.6%, Pumecitinib nasal spray 0.6%(twice daily)
- Where
- 20 sites in China
- Volunteers
- 179 people
- Sponsor
- Prime Gene Therapeutics Co., Ltd.
Allergic Rhinitis, Allergic Rhinoconjunctivitis
PURETHAL® Mites Dose Range Finding Study in Patients With Persistent Allergic Rhinitis/Rhinoconjunctivitis
The objective of the present study is to characterize the dose-response relationship of PURETHAL® Mites with a nasal provocation test in order to support the optimal dose in terms of clinical efficacy and safety.
- Trial name
- NCT01438463
- Testing
- PURETHAL Mites 6,667 AU/ml, PURETHAL Mites 20,000 AU/ml, PURETHAL Mites 50,000 AU/ml
- Where
- 35 sites in Austria, Belgium and 3 more
- Volunteers
- 290 people
- Sponsor
- HAL Allergy
Seasonal Allergic Rhinitis
This Study Contains an Active Drug Treatment Group With Mometasone Furoate Nasal Spray and a Placebo (Dummy) Treatment Group for Seasonal Allergic Rhinitis (SAR). (Study P05073)(COMPLETED)
The purpose of this study is to evaluate how well mometasone furoate nasal spray (MFNS) works to relieve SAR symptoms compared to Placebo when symptoms are induced in a chamber setting.
- Trial name
- NCT00491504
- Testing
- Mometasone Furoate Nasal Spray
- Volunteers
- 310 people
- Sponsor
- Organon and Co
Birch Pollen Allergy, Grass Pollen Allergy
Diagnostic Accuracy of the MADx Multi Array Xplorer (MAX 45k) Automated Laboratory System and the MADx Allergy Explorer Version 2 (ALEX²) - IgE Multiplex Test for the Diagnosis of Pre-defined Groups of Specific High-priority Allergens
About 20% of the general population are affected by an allergy - with an upward trend. Quite often, allergic people do not consider their disease as serious and suffer from subsequent complications, like allergic asthma, later in…
- Conditions
- Birch Pollen Allergy, Grass Pollen Allergy, House Dust Mite Allergy, Cat Allergy
- Trial name
- MADMAX (NCT04435678)
- Testing
- ALEX² test using the MAX 45k automated laboratory system
- Where
- 2 sites in Austria
- Volunteers
- 839 people
- Sponsor
- MacroArray Diagnostics GmbH
Seasonal Allergic Rhinitis
A Study of Tolerability and Safety of a New Cumulative Dose of Grass MATA MPL
There is increasing evidence that the effectiveness of allergy immunotherapy to control symptoms of rhinoconjunctivitis is related to the cumulative dose of allergen or allergoid administered during a single regimen of…
- Trial name
- G104 (NCT03931993)
- Testing
- Grass MATA MPL
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- Allergy Therapeutics
Seasonal Allergic Rhinitis, Driving Ability
Rhinitis, Cognition and Driving Performance
This study investigates the effects of Allergic Rhinitis (AR) on driving ability and memory functions. Our group has previously shown that patients suffering from AR symptoms perform less well on tasks requiring sustained…
- Conditions
- Seasonal Allergic Rhinitis, Driving Ability, Cognition
- Trial name
- NCT01318681
- Testing
- cetirizine 10 mg, fluticasone furoate
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Rhinitis, Allergic, Seasonal
Onset of Action of Mometasone Furoate (MK-0887/SCH 032088) Nasal Spray Compared With Placebo in Seasonal Allergic Rhinitis (C93-184)
This study investigated the onset of symptom relief following initiation of treatment with mometasone furoate (MK-0887/SCH 032088) 200 mcg administered once daily compared with placebo for 14 days.
- Trial name
- NCT03861559
- Testing
- mometasone furoate nasal spray
- Volunteers
- 201 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis
Allergen Challenge Trial of IRL201104 in Seasonal Allergic Rhinitis
The purpose of this allergen challenge study is to assess the efficacy of IRL201104 compared with placebo in adult participants with seasonal allergic rhinitis.
- Trial name
- NCT05098522
- Testing
- IRL201104
- Where
- 2 sites in United Kingdom
- Volunteers
- 63 people
- Sponsor
- Revolo Biotherapeutics
Allergic Rhinitis
Fexofenadine HCl 180 mg, Montelukast Sodium 10 mg and Placebo in Suppression of Wheal and Flare Induced by Seasonal Allergen
Examine the relative potency, onset of action and duration of action of fexofenadine HCl 180 mg (Allegra) and montelukast sodium 10 mg (Singulair) as compared to placebo on skin wheals and flares induced by seasonal allergen.
- Trial name
- NCT00638118
- Testing
- Fexofenadine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Sanofi
Asthma With Allergic Rhinitis
Tezepelumab in Allergic Rhinitis and Asthma Study (TEZARS)
The goal of this clinical trial is to learn about how well tezepelumab (pronounced TEZ e PEL ue mab), a Health Canada-approved drug for severe asthma, works in participants with coexisting allergic asthma and allergic rhinitis…
- Trial name
- TEZARS (NCT06189742)
- Testing
- Tezepelumab
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Dr. Anne Ellis