Clinical trials: Seasonal Allergies
Allergic Rhinitis, Allergic Rhinoconjunctivitis
Efficacy and Safety of SUBLIVAC Phleum for Immunotherapy of Grass Pollen-Allergy
The purpose of this study is to assess safety, tolerability and demonstrate a dose response signal using Total Symptom Score (TSS), based on challenges with grass pollen in an Environmental Exposure Chamber (EEC), followed by…
- Trial name
- NCT02556801
- Testing
- SUBLIVAC FIX Phleum Prat.
- Where
- Canada
- Volunteers
- 168 people
- Sponsor
- HAL Allergy
Rhinitis, Allergic, Perennial and Seasonal
A Study to Assess Intranasal Repeat Dose Effect of Levocabastine in the Subjects With Allergic Rhinitis
This study will be a randomized, double blind, placebo controlled, 3-way cross over design in allergic rhinitis subjects. Subjects will receive repeat doses of intra-nasal levocabastine for 7 days in each period and the duration…
- Trial name
- NCT01949051
- Testing
- Levocabastine
- Where
- Canada
- Volunteers
- 78 people
- Sponsor
- GlaxoSmithKline
Rhinitis, Allergic, Perennial
Validation Of Preference Module Of Experience With Allergic Rhinitis Nasal Sprays Questionnaire (EARNS-Q)
The Protocol section needs to be updated using the following text "The main goal of the study was to validate the Preference Module of the EARNS-Q and to test the reliability using Treatment Satisfaction Questionnaire for…
- Trial name
- NCT00346775
- Testing
- Beclomethasone dipropionate, Flunisolide
- Where
- 7 sites in United States
- Volunteers
- 97 people
- Sponsor
- GlaxoSmithKline
Allergic Rhinitis, Seasonal
A Study of GR1802 Injection in Patients With Seasonal Allergic Rhinitis.
Allergic rhinitis (AR) is a non-infectious chronic inflammatory disease of the nasal mucosa mainly mediated by immunoglobulin E after exposure to allergens in atopic individuals.
- Trial name
- NCT07199257
- Testing
- GR1802 injection
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Genrix (Shanghai) Biopharmaceutical Co., Ltd.
Allergic Rhinitis, Seasonal Allergic Rhinitis
Post Marketing Surveillance for Contac Bien Z in Japan
This is a post-marketing surveillance study on a marketed cetrizine hydrochloride formulation.
- Trial name
- NCT02020902
- Testing
- Cetrizine hydrochloride
- Where
- Japan
- Volunteers
- 1,552 people
- Sponsor
- GlaxoSmithKline
Birch Pollen Allergy
Study to Evaluate Safety and Tolerability of sc Immunotherapy With DM-101 in Adults With Birch Pollen Allergy
Randomized, double-blind placebo-controlled phase I study to investigate the safety and tolerability of ascending doses of DM-101 in adult subjects with birch pollen allergy.
- Trial name
- NCT04266028
- Testing
- DM-101
- Where
- Finland
- Volunteers
- 27 people
- Sponsor
- Desentum Oy
Rhinitis, Allergic, Seasonal
An Approved Drug to Study a New Indication for Allergic Rhinitis (0476-327)
The purpose of this trial is to evaluate the efficacy and safety of an investigational drug in adult patients with allergic rhinitis.
- Trial name
- NCT00127647
- Testing
- montelukast sodium, Comparator: pranlukast
- Volunteers
- 1,375 people
- Sponsor
- Organon and Co
Polymorphic Light Eruption, Psoriasis
Regulatory T Cells (Tregs) in Polymorphic Light Eruption
Polymorphic light eruption (PLE) is a photodermatosis with an extremely high prevalence, particularly among young women (up to 20%).
- Conditions
- Polymorphic Light Eruption, Psoriasis, Atopic Eczema
- Trial name
- NCT00555178
- Where
- 2 sites in Austria
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Allergic Conjunctivitis
A Methodology Development Environmental Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis
A Multi-Center, Double-Masked, Randomized, Parallel-Group, Vehicle-Controlled, Methodology Development Environmental Clinical Trial with Reproxalap Ophthalmic Solutions (0.25% and 0.5%) in Subjects with Seasonal Allergic…
- Trial name
- NCT03660878
- Testing
- Reproxalap Ophthalmic Solution (0.25%), Reproxalap Ophthalmic Solution (0.5%), Vehicle Ophthalmic Solution
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Aldeyra Therapeutics, Inc.
Seasonal Allergic Rhinitis
A Clinical Study Evaluating the Efficacy and Safety of SHR-1819 Injection in Patients With Seasonal Allergic Rhinitis
This study is a multicenter, randomized, double-blind, placebo-controlled Phase III clinical trial aimed at evaluating the efficacy, safety, pharmacokinetics (PK), pharmacodynamics (PD), and immunogenicity of SHR-1819 injection…
- Trial name
- NCT07688772
- Testing
- SHR-1819 Injection
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Guangdong Hengrui Pharmaceutical Co., Ltd
Rhinitis
A Study of Onset of Action of Loratadine and Fexofenadine in Participants With Seasonal Allergic Rhinitis (P08712)
The purpose of this study is to determine the onset of action of two commercially available over-the-counter antihistamines (Loratadine and Fexofenadine) in a model of seasonal allergic rhinitis (SAR).
- Trial name
- NCT01469234
- Testing
- loratadine, fexofenadine
- Volunteers
- 255 people
- Sponsor
- Bayer
Depression
Examining the Link Between Depression and Seasonal Allergies
This study will examine whether spring and fall seasonal depression in individuals with high sensitivity to pollen is linked to seasonal increases in tree and ragweed pollen.
- Trial name
- NCT00770068
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Maryland, Baltimore
Seasonal Allergic Rhinitis
Intranasal Steroids and the Nasal Ocular Response
Eye symptoms of tearing, redness and itch frequently occur in patients with allergic rhinitis or hayfever. The purpose of this study is to learn whether placing allergen (the substance that causes allergies) in the nose several…
- Trial name
- NCT00473915
- Testing
- fluticasone furoate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Seasonal Allergic Rhinitis
Evaluation of the Beneficial Effects of a Nasal Spray of Resveratrol in Children With Seasonal Allergic Rhinitis
The aim of this study is to evaluate whether treatment with a nasal spray based on resveratrol has some benefit in patients with seasonal allergic rhinitis, mild, moderate, or severe.
- Trial name
- NCT02130440
- Testing
- Resveratrol nasal spray
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Campania Luigi Vanvitelli
Allergic Rhinitis
Component Resolved Diagnostics (CRD) and mHealth for Pollen Allergy In Southern Europe.
Pollen allergic rhinitis is a very common condition whose symptomatic treatment is not always sufficient or satisfactory. The indication for allergic immunotherapy (IT) therefore often arises.
- Trial name
- IT-2020-MC (NCT03636919)
- Testing
- e-BOOK
- Where
- France
- Volunteers
- 900 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Rhinitis, Allergic, Seasonal
723/726 Proof of Concept Study in Allergen Challenge Chamber in Hannover
This is a randomised, double-blind, placebo-controlled 4-period cross-over study to assess the efficacy and safety of repeat dose intranasal GSK1004723 (1000µg), oral GSK835726 (10mg) and cetirizine (10mg) in the environmental…
- Trial name
- NCT00972504
- Testing
- GSK835726 10mg, GSK1004723 1000mcg, Cetirizine 10mg
- Where
- Germany
- Volunteers
- 54 people
- Sponsor
- GlaxoSmithKline
Allergic Rhinitis
Cellulose Powder Against Grass Pollen Allergic Rhinitis
Background: A nasally applied cellulose powder is increasingly used in many countries as a remedy for allergic rhinitis. In 2009, a 4-week study in birch pollen-allergic children showed a reduction in nasal symptoms.
- Trial name
- CPARGPDBPC (NCT03039816)
- Testing
- Nasaleze
- Where
- 3 sites in Sweden, Ukraine
- Volunteers
- 108 people
- Sponsor
- Nasaleze International Ltd
Seasonal Allergic Rhinitis
Safety and Efficacy Study of Epinastine Nasal Spray in Subjects With Seasonal Allergic Rhinitis (P08648)
The purpose of this study is to determine the safety and efficacy of epinastine nasal spray compared to placebo for the treatment of subjects with seasonal allergic rhinitis
- Trial name
- NCT00564421
- Testing
- epinastine nasal spray, low concentration, low dose volume, epinastine nasal spray, low concentration, high dose volume, epinastine nasal spray, high concentration, low dose volume
- Volunteers
- 798 people
- Sponsor
- Merck Sharp & Dohme LLC
Seasonal Allergic Rhinitis
Efficacy and Safety of Fixed Dose Combination (FDC) of Olopatadine Hydrochloride and Mometasone Furoate Nasal Spray (Molo; Also Referred as GSP 301) in the Treatment of Seasonal Allergic Rhinitis (SAR)
A single-center, double-blind, placebo-controlled study of FDC olopatadine hydrochloride and mometasone furoate nasal spray (Molo; also referred as GSP 301) was conducted in subjects with seasonal allergic rhinitis.
- Trial name
- GSP 301- PoC (NCT03444506)
- Testing
- Molo 1 (also referred as GSP 301-2 NS), Molo 2 (also referred as GSP 301-1 NS), DYMISTA nasal spray
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- Glenmark Pharmaceuticals Ltd. India
Rhinitis, Allergic, Seasonal
A Dose-finding Study of ASP4070
The objective of this study was to evaluate the efficacy, safety, and dose-response of ASP4070 vaccinated in patients with cedar pollinosis.
- Trial name
- NCT03101267
- Testing
- ASP4070
- Where
- Japan
- Volunteers
- 150 people
- Sponsor
- Astellas Pharma Inc