Clinical trials: Secondary Headache Disorders
Post Traumatic Headache, Cervicogenic Headache
Comparative Effects of Post Isometric Relaxation and Reciprocal Inhibition in Individuals With Cervicogenic Headache.
This study aims to compare the effects of Post Isometric Relaxation (PIR) and Reciprocal Inhibition (RI) in individuals with cervicogenic headache, a secondary headache originating from dysfunction of the cervical spine…
- Trial name
- NCT07838545
- Testing
- Post Isometric Relaxation, Reciprocal Inhibition
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Foundation University Islamabad
Brain Concussion, Post-Concussion Syndrome
Exercise in Postconcussion Symptoms and Posttraumatic Headache
The goal of this clinical trial is to compare two models of delivery of guided exercise in patients with exercise intolerance after mild head injury.
- Conditions
- Brain Concussion, Post-Concussion Syndrome, Post-Traumatic Headache, Craniocerebral Trauma
- Trial name
- NCT06015451
- Testing
- Sub-symptom threshold exercise
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- St. Olavs Hospital
Cervicogenic Headache
Traditional Chinese Cervical Manipulation for Cervicogenic Headache
Background Cervical spondylosis is a prevalent condition. Studies has shown that it is a leading cause for headache, which is termed cervicogenic headache (CGH). The prevlance of CGH among severe headache is 17.5%.
- Trial name
- NCT06434051
- Testing
- Traditional Chinese cervical manipulation
- Where
- 2 sites in Hong Kong
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Preoperative Neutrophil-to-Lymphocyte Ratio (NLR), Postdural Puncture Headache
Neutrophil to Lymphocyte Ratio and Postdural Headache
This study will aim to investigate whether systemic inflammatory markers-especially the neutrophil-to-lymphocyte ratio (NLR)-obtained from preoperative complete blood counts can predict the development of post-dural puncture…
- Trial name
- NCT07075874
- Testing
- PDPH
- Where
- Turkey (Türkiye)
- Volunteers
- 821 people
- Sponsor
- Istinye University
Posttraumatic Headache
Non-pharmacological Treatment of Patients at Risk of Developing Persistent Post-traumatic Headache: The PTHEENOT Study
The goal of this mixed method study is to test and evaluate the effect of an early interdisciplinary non-pharmacological treatment of patients at risk of developing persistent posttraumatic headache in order to prevent the…
- Trial name
- NCT06466499
- Testing
- The intervention group
- Where
- Denmark
- Volunteers
- 104 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Cervicogenic Headache, Cervicogenic Headaches
Baseline Cervical Joint Position Error and Headache Intensity
Cervicogenic headache is a type of headache associated with problems or dysfunction in the neck. People with cervicogenic headache may experience headache pain along with neck pain, reduced neck movement, and difficulties with…
- Trial name
- NCT07796711
- Testing
- Routine clinician-directed physiotherapy
- Where
- India
- Volunteers
- 126 people
- Sponsor
- Saveetha University
Theophylline, Sumatriptan
Theophylline, Versus Sumatriptan and Gabapentin in The Treatment of Post-Dural Puncture Headache
The aim of this study is to compare the safety and efficacy of theophylline, sumatriptan, and gabapentin in the treatment of post-dural puncture headache.
- Conditions
- Theophylline, Sumatriptan, Gabapentin, Post-Dural Puncture Headache
- Trial name
- NCT07515456
- Testing
- Theophylline, Sumatriptan, Gabapentin
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Tanta University
Cervicogenic Headache
Osteopathic Care Combined With Physiotherapy and Pain Education for Cervicogenic Headache
Introduction: Cervicogenic headache (CH) is a secondary headache associated with non-traumatic dysfunctions of the cervical region.
- Trial name
- NCT07794319
- Testing
- Osteopathic Care, Physiotherapy
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Centro Universitário Augusto Motta
Chronic Migraine, Medication Overuse Headache
Mindfulness Therapy for Chronic Migraine
The aim is to assess the efficacy of adding on a Mindfulness-based therapy to pharmacological prophylaxis (experimental group: pharmacological prophylaxis + Mindfulness) against pharmacological prophylaxis only (control group) on…
- Trial name
- Mind-CM (NCT03671681)
- Testing
- Mindfulness, Prophylactic
- Where
- Italy
- Volunteers
- 177 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Post Dural Puncture Headache
Optic Nerve Sheath Diameter for Predicting Post-Dural Puncture Headache in Cesarean Section Patients
Some patients develop headache after spinal anesthesia used during cesarean section. This condition is called post-dural puncture headache (PDPH). Early identification of patients at risk may improve patient care.
- Trial name
- NCT07497945
- Testing
- Optic Nerve Sheath Diameter Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Kocaeli University
Cervicogenic Headache, Tension-Type Headache
Chiropractic Spinal Manipulation for Headache
This is a pilot and feasibility randomized controlled trial to assess the efficacy of chiropractic spinal manipulative therapy in patients with tension-type and cervicogenic headache.
- Trial name
- NCT05240547
- Testing
- Spinal Manipulation
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Real Centro Universitario Maria Cristina
Post-Traumatic Headache
Dexamethasone for Post Traumatic Headache
This is a randomized study of intravenous metoclopramide + intravenous dexamethasone versus intravenous metoclopramide for patients with acute post-traumatic headache.
- Trial name
- NCT04799015
- Testing
- Dexamethasone, Metoclopramide 10mg
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Montefiore Medical Center
Sphenopalatine Ganglion Block, Adrenaline
Sphenopalatine Ganglion Block for Post-Dural Puncture Headache in Orthopedic Patients
The aim of this study is to assess the efficacy, onset and duration of analgesia of sphenopalatine ganglion bock (SPGB) using lidocaine 4% with adrenaline as a treatment of postoperative Post dural puncture headache (PDPH) of…
- Conditions
- Sphenopalatine Ganglion Block, Adrenaline, Post-Dural Puncture Headache, Orthopedic
- Trial name
- NCT04657952
- Testing
- Sphenopalatine Ganglion Block, Medical Treatment
- Volunteers
- 60 people
- Sponsor
- Tanta University
Post-Traumatic Headache
A Study to Test if Fremanezumab Reduces Headache in Participants With Posttraumatic Headache (PTH)
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the safety and efficacy of fremanezumab in adult participants aged 18 to 70 years, inclusive, for the prevention of PTH.
- Trial name
- NCT03347188
- Testing
- Fremanezumab
- Where
- 33 sites in United States
- Volunteers
- 87 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Cervicogenic Headache
Relation Between Cervicogenic Headache and Forward Head Posture
This study will be designed to determining whether there is a relationship between CGH and cervical posture which may potentially provide physical therapists with evidence supporting the assessment and treatment of abnormal…
- Trial name
- NCT04722913
- Testing
- Photogrametry , flexion rotation (FRT) test, Diagnosis of CGH according diagnostic criteria of the Cervicogenic Headache International Study Group (CHISG)
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Cairo University
Cervicogenic Headache
Manual Therapy and Exercise in Patients With Cervicogenic Headache
Hypothesis: The group of cervicogenic headache patients receiving upper cervical and upper thoracic thrust manipulation will demonstrate significant and clinically important changes in outcomes when compared to the mobilization…
- Trial name
- NCT01580280
- Testing
- Thrust Manipulation, Non-thrust Mobilization and Exercise
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Post-Dural Puncture Headache
Comparison of the Effect of Aminophylline, Magnesium Sulphate and Placebo in Prevention of Post Dural Puncture Headache in Parturient Undergoing Caesarean Section.
This study will be conducted to better comprehend the effect of aminophylline in comparison to magnesium sulphate on preventing and/or treating PDPH.
- Trial name
- NCT06272916
- Volunteers
- 630 people
- Sponsor
- Assiut University
Post-Dural Puncture Headache
Effectiveness of Nebulized Dexmedetomidine for Treatment of Obstetric Post-Dural Puncture Headache
Postdural puncture headache (PDPH) is a common complication, following neuraxial techniques. The obstetric population is particularly prone to PDPH. Therefore, treatment of PDPH is a key issue in obstetric anesthesia.
- Trial name
- NCT04327726
- Testing
- Dexmedetomidine Nebulization, 0.9% Saline Nebulization
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Zagazig University
Post-Dural Puncture Headache, Hypotension
Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section
The goal of this clinical trial is to compare different approaches of spinal anesthesia in pregnant females who are having cesarean section.
- Conditions
- Post-Dural Puncture Headache, Hypotension, Spinal Shock, Hematoma
- Trial name
- NCT05637645
- Testing
- Midline Approach, Paramedian Approach, Taylors approach
- Where
- 4 sites in Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bahawal Victoria Hospital Bahawalpur
Post-dural Puncture Headache
Post-dural Puncture Headache - Needles and Biomarkers in CSF
Post-dural puncture headache (PDPH) is the most common complication following lumbar puncture (LP). The frequency varies widely depending on a number of factors, among which patient characteristics, case ascertainment, gauge and…
- Trial name
- NCT02384031
- Testing
- Traumatic needle, Atraumatic needle
- Where
- Norway
- Volunteers
- 172 people
- Sponsor
- Nordlandssykehuset HF