Clinical trials: Secondary Pancreatic Diabetes
Secondary Pancreatic Diabetes
Closed-loop Insulin Delivery Systems in Pancreatic Diabetes
The purpose of this study is to evaluate the metabolic and the safety outcomes in people living with pancreatic diabetes (pancreatitis or pancreatectomy-induced diabetes) and using a closed-loop insulin delivery systems…
- Trial name
- IADIASP (NCT06227650)
- Testing
- hybrid closed loop insulin delivery system
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Sud Francilien
Pancreatic Cancer, Chronic Pancreatitis
Evaluation of a Mixed Meal Test for Diagnosis and Characterization and Type 3c Diabetes Mellitus Secondary to Pancreatic Cancer and Chronic Pancreatitis (DETECT)
The Coordinating and Data Management Center (CDMC) at MD Anderson Cancer will be responsible for the coordination and data management for the Evaluation of a mixed meal test for Diagnosis and characterization of Type 3c diabetes…
- Conditions
- Pancreatic Cancer, Chronic Pancreatitis, Diabetes Mellitus Type 3c
- Trial name
- NCT03460769
- Testing
- Data Management and Monitoring
- Where
- 10 sites in United States
- Volunteers
- 775 people
- Sponsor
- M.D. Anderson Cancer Center
Melanoma, Cervical Carcinoma
A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors
This is a Phase 1, multiple dose, ascending-dose escalation study and expansion study designed to define a maximum tolerated dose and/or recommended dose of XmAb22841 monotherapy and in combination with pembrolizumab; to assess…
- Conditions
- Melanoma, Cervical Carcinoma, Pancreatic Carcinoma, Triple Negative Breast Cancer
- Trial name
- DUET-4 (NCT03849469)
- Testing
- XmAb®22841, Pembrolizumab (Keytruda®)
- Where
- 28 sites in United States
- Volunteers
- 78 people
- Sponsor
- Xencor, Inc.
Pancreatic Cancer
Active Anti-diabetic Treatment Plus Chemotherapy for Pancreatic Cancer Related Diabetes
The purpose of this study is to evaluate the efficacy of anti-diabetic treatment on improving the overall survival for metastatic pancreatic cancer patients complicated by diabetes receiving gemcitabine and nab-paclitaxel…
- Trial name
- PTCA199-16 (NCT07272109)
- Testing
- Nab-paclitaxel, Gemcitabine (1000 mg/m2), Anti-Diabetics
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Fudan University
Chronic Pancreatitis, Type 2 Diabetes Mellitus
The Incretin Effect in Patients With Chronic Pancreatitis
The phenomenon that oral glucose elicits a higher insulin response than does intravenous (iv) glucose, even at identical plasma glucose (PG) profiles (isoglycemia), is called the incretin effect.
- Trial name
- NCT00638573
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Pancreatic Surgey, Diabetes Mellitus
Pancreatic Surgery and Risk Factors
The goal of this observational study is to learn about post-pancreatic surgery diabetes mellitus(PCRD).The main questions it aims to answer are: 1. What are the clinical characteristics of PCRD? 2.
- Trial name
- NCT06585046
- Testing
- pancreatic surgery
- Volunteers
- 382 people
- Sponsor
- Shanghai Changzheng Hospital
Pancreatic Cancer
Ipilimumab +/- Vaccine Therapy in Treating Patients With Locally Advanced, Unresectable or Metastatic Pancreatic Cancer
Research Hypothesis: Ipilimumab (an antibody that blocks negative signals to T cells) administered alone or in combination with a pancreatic cancer vaccine (allogeneic pancreatic tumor cells transfected with a GM-CSF gene), has…
- Trial name
- NCT00836407
- Testing
- Ipilimumab, Pancreatic Cancer Vaccine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Metastatic Pancreatic Adenocarcinoma
FOLFIRINOX Followed by Ipilimumab With Pancreatic Tumor Vaccine in Treatment of Metastatic Pancreatic Cancer
This study will enroll patients who have metastatic pancreatic cancer with stable disease on FOLFIRINOX chemotherapy. The main purpose of this study is to compare survival between patients that receive ipilimumab and a pancreatic…
- Trial name
- NCT01896869
- Testing
- Ipilimumab, Vaccine, FOLFIRINOX
- Where
- 3 sites in United States
- Volunteers
- 83 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Acute Pancreatitis (AP), Diabetes Mellitus
Hyperglycemia and Acute Pancreatitis
The goal of this observational study is to learn about post-acute pancreatitis diabetes mellitus (PPDM-A). The main questions it aims to answer are: 1. What are the clinical characteristics of PPDM-A? 2.
- Trial name
- NCT06590233
- Volunteers
- 4,500 people
- Sponsor
- Shanghai Changzheng Hospital