Clinical trials: Secondary Prevention of Coronary Heart Disease
Myocardial Infarction, Acute Coronary Syndrome
Impact at One Year of a Secondary Prevention Educational Program on Cardiovascular Risk Factors
In secondary prevention, the beneficial role of cardiac rehabilitation programs after myocardial infarction, percutaneous coronary intervention or coronary artery bypass is now well established.
- Trial name
- OLIMPIC (NCT00758810)
- Where
- 4 sites in France
- Volunteers
- 354 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Glucose Metabolism Disorders, Coronary Artery Disease
Acarbose and Secondary Prevention After Coronary Stenting
The purpose of this study is to determine whether the intervention for newly diagnosed abnormal glucose tolerance after coronary stenting will improve the long-term clinical outcome.
- Trial name
- NCT00221156
- Testing
- Acarbose
- Where
- 3 sites in Japan
- Volunteers
- 300 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Cardiovascular Disease
Impact of Text Messages to Promote Secondary Prevention After Acute Coronary Syndrome
The study is a two-arm, parallel, randomized clinical trial. The purpose of the study is to evaluate the effectiveness of automated mobile phone text message-based intervention for secondary prevention after acute coronary…
- Trial name
- IMPACS (NCT03414190)
- Testing
- Mobile phone text message
- Where
- Brazil
- Volunteers
- 160 people
- Sponsor
- Federal University of Minas Gerais
Acute Coronary Syndrome, Dyslipidemias
Low-density Lipoprotein Cholesterol Reduction With State-of-the-art Therapy in Secondary Prevention and Major Cardiovascular Adverse Events: Republic of Srpska Registry
Recent trials have demonstrated that a reduction in low-density lipoprotein cholesterol (LDL-C) reduces cardiovascular adverse events following acute coronary syndrome (ACS).
- Trial name
- RS-ACS (NCT05081336)
- Testing
- Statin
- Where
- Bosnia and Herzegovina
- Volunteers
- 500 people
- Sponsor
- University Clinical Centre of Republic of Srpska
Rheumatic Heart Disease, Rheumatic Heart Disease in Children
Effectiveness of a School-centered Prevention Program on Prevalence of Latent Rheumatic Heart Disease
The overall objective is to evaluate the effectiveness of a school-centered primary and secondary prevention program on the prevalence of latent rheumatic heart disease among schoolchildren in Nepal, and to investigate the role…
- Trial name
- NEPAL4 (NCT05504928)
- Testing
- School nurse program
- Where
- Nepal
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Myocardial Infarction, Acute, ST Segment Elevation Myocardial Infarction
A Trial on the Role of Community Pharmacist in Improving Adherence and Clinical Outcomes in Post-Infarction
The purpose of this pilot study is to evaluate the effectiveness of the active involvement of Community Pharmacists in improving adherence to medical prescriptions in patients with acute myocardial infarction (AMI), reducing the…
- Conditions
- Myocardial Infarction, Acute, ST Segment Elevation Myocardial Infarction, Non-ST Elevation Myocardial Infarction (nSTEMI)
- Trial name
- IM-ADHERENCE (NCT03621111)
- Testing
- Patient-counseling, Patient self-administered questionnaire, Pills counts
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda ULSS 5 Polesana
Cardiovascular Diseases, Chronic Disease
Improving Therapeutic Adherence in Cardiovascular Secondary Prevention.
The goal of this open label randomized controlled trial is to evaluate the efficacy of an intervention through health education based on the Chronic Care Model's implementation to increase therapeutic adherence in patients with…
- Conditions
- Cardiovascular Diseases, Chronic Disease, Secondary Prevention, Coronary Disease
- Trial name
- AT-PSC (NCT06510946)
- Testing
- (Health education program) To increase therapeutic adherence in patients with secondary prevention for cardiovascular disease
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Patients With Coronary Artery Disease
Comparison Between HIIT and MICT on the Phase III of Cardiac Rehabilitation
The increase in the prevalence of cardiovascular diseases (CVD), directly associated with the aging of the population, is a concern for public health in Portugal.
- Trial name
- NCT03538119
- Testing
- High Intensity Interval Training Program, Moderate Intensity Continuous Training Program
- Where
- Portugal
- Volunteers
- 69 people
- Sponsor
- University of Évora
Atrial Fibrillation
Secondary Prevention of Atrial Fibrillation (Impact of Renin-Angiotensin-Aldosterone System Inhibition)
In the present application, we propose to refine and extend current insight into AAF mechanism and therapy by examining the importance of pharmacologic RAAS inhibition, ACE genotype, and their interaction in secondary AF…
- Trial name
- NCT01233635
- Testing
- no drug, start cozaar, continue cozaar
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- University of Pittsburgh
Defibrillators, Tachycardia
Observational Study of Patient Comprehension, Perception, Fears and Appreciation Following Home-Monitoring Implementation
Describe the mutual influences between trainings realized in implantation centers, medico-technical knowledges, technical implementation, perception, fears and appreciation felt by the patients during Home Monitoring…
- Trial name
- Educ@t (NCT01006746)
- Testing
- Remote monitoring by Home Monitoring system
- Where
- France
- Volunteers
- 571 people
- Sponsor
- Biotronik France
Coronary Heart Disease, Artificial Intelligence
Effects of AI Assisted Follow-up Strategy on Secondary Prevention in CABG Patients
The present study is trying to find out whether artificial intelligence assisted follow-up strategy will improve secondary prevention in CABG patients.
- Conditions
- Coronary Heart Disease, Artificial Intelligence, Sleep Apnea
- Trial name
- NCT04636996
- Testing
- artificial intelligence assisted follow-up
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Atrial Fibrillation (AF), Atrial Fibrillation (Prevention of Stroke)
The Southern-Norway Post-Stroke Atrial Fibrillation Study
This study evaluates whether a procedure using a new wireless heart sensor patch is equal to or better than the standard hospital procedures and equipment at detecting an irregular heartbeat called Atrial Fibrillation (AF) after…
- Conditions
- Atrial Fibrillation (AF), Atrial Fibrillation (Prevention of Stroke), Ischemic Stroke, Secondary Prevention
- Trial name
- SNAPS (NCT07407790)
- Testing
- Patch ECG, Standard Care (in control arm)
- Where
- Norway
- Volunteers
- 450 people
- Sponsor
- Sorlandet Hospital HF
Coronary Heart Disease
The VA HDL Intervention Trial (HIT): Secondary Prevention of Coronary Heart Disease in Men With Low HDL-Cholesterol and Desirable LDL-Cholesterol
This was a double-blind randomized trial comparing 1200 mg per day of gemfibrozil with placebo in 2531 men with coronary heart disease, an HDL-C of 40mg/dl or less, an LDL-C of 140 mg/dl or less, and triglycerides of 300mg/dl or…
- Trial name
- HIT (NCT00283335)
- Testing
- gemfibrozil
- Where
- United States
- Volunteers
- 2,531 people
- Sponsor
- VA Office of Research and Development
Diabetes Mellitus, Acute Coronary Syndrome
Aspirin Twice a Day in Patients With Diabetes and Acute Coronary Syndrome
To compare treatment with Aspirin Protect® twice a day (100 mg in the morning and 100 mg in the evening) versus Aspirin Protect® 100 mg once per day on a composite end-point of ischemic events in diabetic patients, or in patients…
- Conditions
- Diabetes Mellitus, Acute Coronary Syndrome, Coronary Artery Disease, Obesity
- Trial name
- ANDAMAN (NCT02520921)
- Testing
- Novel strategy Aspirin, Conventional strategy Aspirin
- Where
- France
- Volunteers
- 2,484 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Heart Disease
Impact of Motivational Interviews Within Pharmacy Care Upon Adherence to Cardiovascular Medicines
Introduction: In the United Kingdom(UK), about 838,000 men and 394,000 women have had a myocardial infarction (MI) and will need secondary prevention medications.
- Trial name
- Pharmacycare (NCT01920009)
- Testing
- Pharmacist counselling session with a motivational interview
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University College, London
Coronary Artery Disease
Interactive Voice Response Telephone Technology for the Treatment of Smoking in Patients With Heart Disease
A randomized control trial is planned to evaluate an interactive voice response (IVR) mediated follow-up and triage system, against usual care, to help smokers hospitalized with Coronary Heart Disease (CHD) to quit smoking.
- Trial name
- IVR (NCT00449852)
- Testing
- Interactive Voice Response
- Where
- Canada
- Volunteers
- 440 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Comorbidities and Coexisting Conditions, Ethics
eCardiacRehab - a Hybrid Patient-Centered eHealth Programme
The overall aim of eCardiacRehab trial is to meet rehabilitation needs of patients with coronary artery disease (CAD) regardless of their access to traditional place-based rehabilitation by developing and evaluating the efficacy…
- Conditions
- Comorbidities and Coexisting Conditions, Ethics, Continuity of Patient Care, Older Adults (65 Years and Older)
- Trial name
- eCardiacRehab (NCT07590635)
- Testing
- eCardiacRehab
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- Haukeland University Hospital
Arrhythmias, Cardiac, Atrioventricular Block
ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing
The goal of this observational study is to evaluate the clinical characteristics of patients undergoing permanent cardiac pacing and to compare procedural efficacy and safety of different implantation approaches in the clinical…
- Conditions
- Arrhythmias, Cardiac, Atrioventricular Block, Reduced Systolic Function, Atrial Fibrillation
- Trial name
- TREEBEARD (NCT06324682)
- Testing
- Cardiac pacing - Conventional RV pacing, Cardiac pacing - Conduction System Pacing, Cardiac pacing - Cardiac resynchronization therapy (pacing - CRTP - or defibrillation - CRTD)
- Where
- 31 sites in Italy
- Volunteers
- 8,400 people
- Sponsor
- University Hospital of Ferrara
Nonfatal Myocardial Infarction, Coronary Death
Association Between Low Dose Acetylsalicylic Acid (ASA) and Proton Pump Inhibitors and Risk of Acute Myocardial Infarction or Coronary Death
The purpose of this study is to estimate the risk of myocardial infarction (MI)/coronary death associated with use of monotherapy low dose ASA (single antiplatelet) as well as concomitant use of monotherapy low dose ASA and…
- Trial name
- NCT01360047
- Where
- Spain
- Volunteers
- 39,513 people
- Sponsor
- AstraZeneca
Coronary Artery Disease
A Trial of Stress Reduction in the Secondary Prevention of Coronary Heart Disease in Blacks
The overall hypothesis of this study is that a cardiac rehabilitation program with meditation will be more effective than cardiac rehabilitation alone in improving blood flow through the diseased coronary arteries in African…
- Trial name
- CCR (NCT01810029)
- Testing
- Cardiac Rehabilitation plus Transcendental Meditation
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Maharishi International University