Clinical trials: Secondary Stroke
Lower Extremity Dysfunction, Stroke
Sensitivity to Change of the Lower Extremity Functional Scale in Patients With Stroke
The purpose of this study was to investigate the reliability, construct validity, and sensitivity to change of the Lower Extremity Functional Scale (LEFS) in individuals affected by stroke.
- Trial name
- NCT01536990
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Mayo Clinic
Ischemic Stroke, Cryptogenic, Transient Ischemic Attack
Smartwatches for Detection of Atrial Fibrillation (AFib) in Secondary Prevention of Cryptogenic Stroke
Scientific Background: In secondary prevention of ischemic stroke, detection of atrial fibrillation (AFib) and subsequent anticoagulation therapy reduce the risk of recurrent stroke by approximately 60%.
- Conditions
- Ischemic Stroke, Cryptogenic, Transient Ischemic Attack, Atrial Fibrillation
- Trial name
- WATCH AFib (NCT06005233)
- Testing
- Smartwatch
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Technical University of Munich
Stroke
Efficiency Study of Traditional Chinese Medicine (TCM) Versus Western Medicine (WM) on Ischemic Stroke
Complex project of Traditional Chinese Medicine (TCM) with Western Medicine (WM) project under stroke unit mode contrast,assuming that the efficiency of TCM on early rehabilitation and secondary prevention of ischemic stroke is…
- Trial name
- NCT00843765
- Testing
- acupuncture, massage and basic TCM treatment, rehabilitation and WM basic treatment
- Where
- China
- Volunteers
- 1,151 people
- Sponsor
- China Academy of Chinese Medical Sciences
Stroke
Mobile Terminal Based Management of Stroke Secondary Prevention Adminstration Effect Research
The investigators want to verify whether mobile application based on stroke strengthen prevention management is more effective than traditional management model or open stroke management platform.
- Trial name
- NCT02618265
- Testing
- Mobile terminal, traditional management, website platform management
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University Third Hospital
Secondary Stroke
A Study to Evaluate Cenvacibart (REGN7508) for Secondary Stroke Prevention in Adult Participants
This study will test an experimental Regeneron drug called cenvacibart (REGN7508) ("study drug") compared with a placebo (a look-alike treatment with no active medicine) on top of background antiplatelet medications.
- Trial name
- ROXI-DAISEN (NCT07876492)
- Testing
- Cenvacibart
- Volunteers
- 6,106 people
- Sponsor
- Regeneron Pharmaceuticals
Stroke
Secondary Prevention and Health Promotion After Stroke
The aim of this study was to examine to what extent a one year population of stroke patients at a university hospital had well regulated risk factors and health problems one year after stroke, and if a structured nurse-led…
- Trial name
- NCT01466907
- Testing
- Secondary prevention, supportive counselling, Standard care until one year follow-up
- Where
- Sweden
- Volunteers
- 597 people
- Sponsor
- Skane University Hospital
Ischemic Stroke
Intracerebral Hemorrhage Due to Oral Anticoagulants: Prediction of the Risk by Magnetic Resonance
The purpose of this study is to determine whether Magnetic Resonance Imaging may predict the risk of Intracerebral Hemorrhage for patients with ischemic stroke who receive indefinite oral anticoagulation
- Trial name
- HERO (NCT02238470)
- Testing
- oral anticoagulants
- Where
- 30 sites in Italy, Spain
- Volunteers
- 1,000 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Ischemic Stroke, Small Vessel Cerebrovascular Disease
Optimal Target Low-density Lipoprotein Cholesterol Level for Small Vessel Occlusion Stroke
Lipid-lowering therapy constitutes a cornerstone of secondary prevention in ischemic stroke; however, current stroke guidelines remain deficient in providing optimal target low-density lipoprotein (LDL)-cholesterol levels…
- Conditions
- Ischemic Stroke, Small Vessel Cerebrovascular Disease, Cholesterol, LDL, Secondary Prevention
- Trial name
- SVO70 (NCT06649240)
- Testing
- Statins and/or Ezetimibe, PCSK9 inhibitor
- Where
- 46 sites in South Korea
- Volunteers
- 4,016 people
- Sponsor
- Seoul National University Hospital
Ischemic Attack, Transient, Stroke
Systematic Follow up of Drug Treatment by Pharmacists in Secondary Prevention After Transient Ischemic Attack
Use of drugs is an important factor in secondary prophylaxis after transient ischemic attack (TIA), but studies show that adherence to the prescribed drugs is often poor.
- Trial name
- NCT02089074
- Testing
- Drug use counselling
- Where
- 6 sites in Norway
- Volunteers
- 265 people
- Sponsor
- Norwegian University of Science and Technology
Insomnia, Secondary, Post-stroke Depression
Efficacy and Safety of Auricular Acupuncture in Treating Insomnia Post-stroke
The goal of this clinical trial is to learn if Auricular acupuncture works to treat Insomnia Post-stroke patients. It will also learn about the safety of Auricular.
- Trial name
- NCT06540664
- Testing
- Auricular Acupuncture needles
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Ischemic Stroke
Quality Improvement in Stroke Prevention (QUISP)
Is a secondary prevention intervention, focused on implementation of standardized pre-printed discharge orders for hospitalists, effective at increasing utilization of the following evidence-based treatments 6 months after…
- Trial name
- NCT00328640
- Testing
- Optimal treatment
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- University of California, San Francisco
Acute Ischemic Stroke
Safety Of A Second Dose Of Tenecteplase In Selected Acute Ischemic Stroke Patients Not Responding To The First Dose
In this pilot safety study, the investigators will give a second dose of Intravenous Tenecteplase (IV TNK) to patients receiving the initial TNK dose within 3 hrs of last known normal (LKN), have a baseline National Institutes of…
- Trial name
- DoubleDoseTNK (NCT06801054)
- Testing
- Tenecteplase (TNK) (0.25 mg/kg, to maximum of 25mg)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Memorial Hermann Health System
Ischemic Stroke, Atrial Fibrillation
Intensive Rhythm Monitoring to Decrease Ischemic Stroke and Systemic Embolism - the Find-AF 2 Study
Patients who have suffered a stroke are having an increased risk of having recurrent stroke in the future. This risk of stroke is increased by atrial fibrillation, which often "comes and goes" (called paroxysmal) and hence…
- Trial name
- Find-AF2 (NCT04371055)
- Testing
- 7-day Holter ECG, Implantable cardiac monitor, Standard of care
- Where
- 52 sites in Germany
- Volunteers
- 5,227 people
- Sponsor
- University of Leipzig
Stroke, Ischemic
Testing a New Treatment Strategy to Improve Secondary Stroke Prevention for Older Adults: The STROKE75+ Trial
The overall aim of this research is to improve secondary stroke prevention for older patients with stroke. In current practice, patients with stroke are often prescribed antiplatelet therapy with either aspirin or clopidogrel to…
- Trial name
- STROKE75+ (NCT07454707)
- Testing
- Edoxaban 15 mg, Aspirin or clopidogrel
- Where
- Canada
- Volunteers
- 1,204 people
- Sponsor
- Sunnybrook Health Sciences Centre
Stroke, Secondary Prevention
Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)
This trial will enroll approximately 6,000 patients with recent embolic stroke of unknown source (ESUS). Patients will be randomized to dabigatran or acetylsalicyclic acid (ASA) (1:1 ratio) and have visits every three months.
- Trial name
- NCT02239120
- Testing
- optional ASA as comedication, ASA 100 mg
- Where
- 569 sites in United States, Argentina and 40 more
- Volunteers
- 5,390 people
- Sponsor
- Boehringer Ingelheim
Stroke
Study to Assess the Safety and Effectiveness of the Penumbra System
This clinical evaluation is a prospective, single-arm, multi-center trial. The purpose of this clinical evaluation is to assess the safety and effectiveness of the Penumbra System in the revascularization of patients presenting…
- Trial name
- NCT00334061
- Testing
- Penumbra System
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Penumbra Inc.
Ischemic Stroke, Atrial Fibrillation Non-Rheumatic
STroke Secondary Prevention With Catheter ABLation and EDoxaban for Patients With Non-valvular Atrial Fibrillation: STABLED Study
Catheter ablation (CA) has been reported to reduce risk of stroke in patients with nonvalvular atrial fibrillation (NVAF) in retrospective studies, but risk and benefit of CA has not been well elucidated in NVAF with recent…
- Trial name
- STABLED (NCT03777631)
- Testing
- Catheter ablation
- Where
- 46 sites in Japan
- Volunteers
- 251 people
- Sponsor
- Nippon Medical School