Clinical trials: Sedation During
Oocyte Retrieval for IVF
Virtual Reality Hypnosis as Sedation During Oocyte Retrieval: Effect on Propofol Consumption
An egg retrieval is performed during an IVF course. This painful procedure is performed using sedation to ensure patient comfort.
- Trial name
- VRH-IVF (NCT07104409)
- Testing
- virtual reality hypnosis device
- Volunteers
- 72 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Mental Health, Anxiety
Anxiety in Children and Families During MRI Under Anesthesia
This prospective randomized controlled study evaluates the impact of age-appropriate therapeutic play and structured parental briefing on perioperative anxiety during pediatric MRI under sedation.
- Trial name
- NCT07693309
- Testing
- Multi-modal Psychological Preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Afyonkarahisar Health Sciences University
Procedural Sedation, Behavior Disorders
The Use of Dexmedetomidine for EEG Sedation in Children With Behavioural Disorders
Children's compliance during diagnostic or therapeutic procedures is a challenge, often requiring the use of sedative and/or analgesic drugs.
- Trial name
- NCT03799783
- Testing
- dexmedetomidine
- Where
- Italy
- Volunteers
- 19 people
- Sponsor
- Azienda Ospedaliera di Padova
Conscious Sedation
An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Colonoscopy
Very often patients receive medication before a diagnostic procedure, like a colonoscopy, to help them relax and stay calm during the procedure. This is called procedural or minimal-to-moderate sedation.
- Trial name
- NCT00261599
- Testing
- AQUAVAN® (fospropofol disodium) Injection, Midazolam HCI
- Where
- 20 sites in United States
- Volunteers
- 300 people
- Sponsor
- Eisai Inc.
Respiratory Failure
Volatile Anesthetic Pharmacokinetics During Extracorporeal Membrane Oxygenation
The goal of this study is to design a pilot trial evaluating the safety, feasibility, pharmacokinetic modeling, and physiological effects of a volatile anesthetic, sevoflurane, directly administered in extracorporeal membrane…
- Trial name
- Vol-ECMO (NCT05680545)
- Testing
- Sevoflurane vaporized in ECMO machines
- Volunteers
- 10 people
- Sponsor
- University Health Network, Toronto
Pediatric Sedation
Evaluation of the Efficacy of Oxygen Therapy and Clinical Feasibility of High Flow Nasal Cannula During Moderate and Deep Sedation in Pediatric Patients
The investigators evaluate the efficacy and safety of routine administration of oxygen during moderate or deep sedation in pediatric patients.
- Trial name
- NCT04852432
- Testing
- high flow nasal cannula, nasal prong
- Where
- South Korea
- Volunteers
- 258 people
- Sponsor
- Seoul National University Hospital
Dental Pain
Buffered Local Anesthetic
The purpose of this research study is to compare responses in children during dental injections of local anesthetic (used for numbing), while children are under deep sedation (breathing on their own, often with a loss of…
- Trial name
- NCT05757648
- Testing
- Non-buffered Anesthetic, Buffered Anesthetic, Onset
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Medical Thoracoscopy
Safety and Efficacy of Dexmedetomidate vs. Midazolam for Procedural Sedation During Medical Thoracoscopy
Medical thoracoscopy can be performed under procedural sedation (conscious sedation) in most of the cases. Procedural sedation is a state where the patient lies comfortably without much movement, does not feel pain and has a…
- Trial name
- DEMISE-MT (NCT07184801)
- Testing
- Dexmedetomidine, Midazolam
- Where
- India
- Volunteers
- 56 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Failed Conscious Sedation During Procedure
The Efficacy and the Safety of Dexmedetomidine Sedation on the Pediatric Intensive Unit(PICU) Patients.
To observe the efficacy and safety of dexmedetomidine sedation on the patients admitted to the pediatric intensive care unit after surgery.
- Trial name
- NCT02296073
- Testing
- Midazolam, Dexmedetomidine, Fentanyl
- Volunteers
- 120 people
- Sponsor
- Anhui Provincial Children's Hospital
Procedural Sedation and Analgesia During Bone Marrow Aspiration and Biopsy
Dexmedetomidine Versus Midazolam Added to Ketamine in Pediatric Patients Undergoing Bone Marrow Aspiration and Biopsy
Group I :The patients will receive midazolam intravenously (i.v.) in a dose of 0.05 mg/kg diluted by 50ml saline over 10 minutes using syringe pump plus 1 mg/kg ketamine (iv).
- Trial name
- NCT03647579
- Testing
- midazolam intravenous infusion of 0.05 mg/kg plus 1 mg/kg ketamine, Dexmedetomidine intravenous infusion of 2mic/kg plus 1 mg/kg ketamine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Sedation, Pediatric
Sedation Safety Assessment Using IPI Monitoring in Pediatric Hematologic Procedures
Pediatric hematologic procedures such as lumbar puncture and bone marrow aspiration often require deep sedation due to pain and the need for immobility.
- Conditions
- Sedation, Pediatric, Integrated Pulmonary Index, BIS
- Trial name
- NCT07733544
- Testing
- Deep Sedation with IPI and BIS Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Sedation, Intubation
Dexmedetomidine Versus Propofol for Sedation During Awake Endotracheal Intubation
The purpose of this study is to compare the sedation effect of dexmedetomidine and propofol when they are both combined with midazolam and remifentanil during awake endotracheal intubation.
- Trial name
- NCT04753515
- Testing
- dexmedetomidine combined with midazolam and remifentanil., propofol combined with midazolam and remifentanil.
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Hypoxemia, Complications
Capnography During ERCP
In the study the value of capnography for avoiding complications during sedation for ERCP is evaluated.
- Trial name
- EndoBreath (NCT01072474)
- Testing
- Capnography, Standard monitoring
- Where
- 3 sites in Germany
- Volunteers
- 242 people
- Sponsor
- Technical University of Munich
Hypoxemia, Hemodynamic Instability
High-Flow Nasal Oxygen During Endoscopic Retrograde Cholangiopancreatography In Geriatric Patients
This prospective, single-centre, randomized controlled trial evaluates whether high-flow nasal oxygen (HFNO) reduces hypoxaemia compared with conventional low-flow oxygen therapy (COT) during endoscopic retrograde…
- Trial name
- HFNO ERCP (NCT07493811)
- Testing
- HFNO, Conventional Oxygen Therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Lung Cancer, Lung; Node
Remifentanil Target Controlled Infusion Versus Standard of Care for Conscious Sedation During EBUS-TBNA
Background: endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive procedure for diagnosing and staging mediastinal lymph node lesions in lung cancer.
- Conditions
- Lung Cancer, Lung; Node, Sedation Complication, Endoscopy
- Trial name
- NCT06033729
- Testing
- Remifentanil TCI, Midazolam injection, Fentanyl
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Scarlata, Simone, M.D.
Conscious Sedation Failure During Procedure, Analgesia
Lidocaine as Local Anesthetics in Children Under Ketamine Sedation
Ketamine seems an obvious choice in the setting of an emergency department in laceration repair. Lidocaine is the local anesthetics widespread used. Ketamine leads to dissociative amnesia.
- Conditions
- Conscious Sedation Failure During Procedure, Analgesia, Anesthesia
- Trial name
- NCT02205502
- Testing
- Lidocaine, Normal saline
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
Propofol, Hypoxia
HFNC and Hypoxia/Desaturation During Radiofrequency Ablation Under Moderate Sedation: A Randomized Clinical Trial
Background: Propofol based sedated anesthesia was widely used in percutaneous radiofrequency ablation and hypoxia/desaturation is one of the most frequent adverse events during this procedure.
- Conditions
- Propofol, Hypoxia, Sedation Complication, Desaturation of Blood
- Trial name
- NCT05212064
- Testing
- high-flow oxygen nasal cannula therapy, nasal cannula oxygen therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhejiang Cancer Hospital
Colonoscopy
Comparison Between Two Different Dosages of Remifentanil During Colonoscopy
The purpose of this randomized double-blind trial is to define the correct dosage of Remifentanil during operative and diagnostic endoscopic procedures.
- Trial name
- NCT01229527
- Testing
- Remifentanil, Meperidine
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Ospedale San Raffaele
Stroke
General Anesthesia Versus Sedation During Intra-arterial Treatment for Stroke
In France, the annual incidence rate of acute ischaemic stroke is around 150 000 patients, 65 % of whom keep long-term disability.
- Trial name
- GASS (NCT02822144)
- Testing
- Etomidate, Succinylcholine, Propofol
- Where
- 4 sites in France
- Volunteers
- 351 people
- Sponsor
- Rennes University Hospital
Sedative During Endoscopy
Implementing Virtual Reality (VR) to Reduce Sedation
The study is a prospective pilot patients aged 21 to 65 undergoing screening colonoscopy or diagnostic upper endoscopy. Patients are administered minimal sedation (2 mg of Versed and 25 mg of Fentanyl) and are given Virtual…
- Trial name
- NCT06349564
- Testing
- Pico 4 Enterprise headset with noise cancelling headphones
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health