Clinical trials: Sedation During
Pediatric Solid Tumor, Pediatric Brain Tumor
Effects of Music and Maternal Voice on Sedation Depth and Sedative Use During Pediatric Magnetic Resonance Imaging.
To evaluate the effects of music and maternal voice in children on sedation depth and sedative use during pediatric magnetic resonance imaging.
- Conditions
- Pediatric Solid Tumor, Pediatric Brain Tumor, Pediatric Cancer
- Trial name
- NCT04944875
- Testing
- Group headphone, Group music, Group maternal voice
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Cirrhosis
Propofol and Fentanyl Versus Midazolam and Fentanyl for Endoscopy Sedation in Cirrhotic Patients
The purpose of this study is to compare propofol associated with fentanyl versus midazolam plus fentanyl for sedation during diagnosis or therapeutic upper gastrointestinal endoscopy (UGE) in cirrhotic patients.
- Trial name
- NCT00906139
- Testing
- Propofol, Midazolam, Fentanyl
- Where
- Brazil
- Volunteers
- 210 people
- Sponsor
- Federal University of São Paulo
Airway Control, Anesthesia
Ketamine Versus Etomidate for Rapid Sequence Intubation
The purpose of this study is to compare the effectiveness and safety of ketamine and etomidate during rapid sequence intubation (RSI).
- Conditions
- Airway Control, Anesthesia, Intubation, Complication
- Trial name
- NCT01823328
- Testing
- Ketamine, Etomidate
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Hennepin Healthcare Research Institute
Confusion
Hypnosis Versus SIVOC by Remifentanil During TAVI Procedures : Iloact on Peripoperative Confusion
TAVI has become a credible alternative to conventional cardiac surgery in aged high-risk patients with aortic valve stenosis. A large part of these procedures are performed with sedation using remifentanil target-controlled…
- Trial name
- HYPSED (NCT03974269)
- Testing
- TAVI : Transcatether Aortic Valve Implantation
- Where
- France
- Volunteers
- 186 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Sleep, Sedation Complication
Closed Loop Acoustic Stimulation During Sedation With Dexmedetomidine
Prospective within-subject study of dexmedetomidine sedation paired with CLAS conditions in repeated blocks. Intervention will consist of CLAS in-phase with EEG slow waves.
- Trial name
- CLASS-D (NCT04206059)
- Testing
- MRI, Quantitative Sensory Testing (QST), Home sleep study
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Premature Neonate
Assessment of Ketamine and Propofol Sedation During LISA Method (Less Invasive Surfactant Administration)
Respiratory distress syndrome (RDS) caused by surfactant deficiency remains one of the major reasons of morbi-mortality in preterm infants and affects 85% of preterm babies born less than 32 week gestational age (wGA).
- Trial name
- ANALISA (NCT03705468)
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Montpellier
Critical Illness, Complication of Ventilation Therapy
Cerebral Autoregulation in Non Neurological Critical Patients.
Brief Summary Cerebral Autoregulation is a well known physiological response to blood pressure changes to maintain the cerebral perfusion.
- Conditions
- Critical Illness, Complication of Ventilation Therapy, Systemic Inflammatory Response Syndrome, Failed Moderate Sedation During Procedure, Sequela
- Trial name
- NCT01731106
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Upper Airway Obstruction, Apnea, Obstructive
Improve Oxygenation and Capnographic Detection During Sedative EGD
The purpose of this study is to compare the effect of mandibular advancement bite block and high flow nasal cannula to standard bite block for oxygenation, capnographic measurement, prevention of hypoxemia, intervention events…
- Trial name
- NCT03138850
- Testing
- Olympus standard bite block, YX mandibular advancement bite block, Optiflow High flow nasal cannula
- Where
- Taiwan
- Volunteers
- 170 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Body Temperature Changes, Anesthesia
Core Temperature Variations During Midazolam vs Propofol Sedation for Neuraxial Anesthesia
The present study is a pilot study aiming to compare the variation in core temperature (measured through the non-invasive device Spot-OnTM3MTM) in patients submitted to neuraxial anesthesia for orthopedic procedures, during…
- Trial name
- NCT02502877
- Testing
- Midazolam, Propofol, Standard
- Where
- Portugal
- Volunteers
- 27 people
- Sponsor
- Hospital da Luz, Portugal
Hypoxemia, Eldery People
HFNC vs Conventional Oxygen During Gastrocolonoscopy in Elderly Patients
This study aims to compare high-flow nasal oxygen (HFNO) with conventional nasal cannula oxygen during sedation for combined upper and lower gastrointestinal endoscopy (gastroscopy and colonoscopy) in patients aged 75 years and…
- Conditions
- Hypoxemia, Eldery People, Endoscopy, Colonoscopy
- Trial name
- NCT07916298
- Testing
- HİGH FLOW NASAL CANNULA OXYGEN, NASAL CANNULA OXYGEN
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Turkish Society of Anesthesiology and Reanimation
Sedation, Flexible Bronchoscopy
Use of Dexmedetomidine for Sedation During Flexible Bronchoscopy in Patients With COPD: A Descriptive Study
To determine safety and effectiveness of dexmedetomidine when administered for conscious sedation during flexible bronchoscopy (FB) in patients with Chronic Obstructive pulmonary Disease (COPD).
- Conditions
- Sedation, Flexible Bronchoscopy, COPD
- Trial name
- NCT00401206
- Testing
- dexmedetomidine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The Cooper Health System
Critically Ill Patients Under Mechanical Ventilation, Sedated Patients
Haemodynamic and Metabolism Response During Early Rehabilitation in Sedated Patients
Despite several positive studies, benefits of early rehabilitation on recovery and motor performance improvement need to be demonstrate.
- Trial name
- NCT02920684
- Testing
- Passive legs mobilisation, Passive cycloergometer, Muscular electrical stimulation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Rouen
ANXIETY
Music Therapy and Sedation for Pain and Anxiety During Oocyte Retrieval
This study is a prospective observational investigation aimed at examining the effect of music intervention on anxiety and pain levels in patients undergoing the ovum pick-up (OPU) procedure under sedation at an IVF center.
- Trial name
- NCT07898358
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Samsun University
Hypoxia, Hysteroscopy
The Effects of Remimazolam on the Incidence of Hypoxia During Sedated Hysteroscopy for Assisted Reproduction in Overweight or Obese Patients
Hypoxia is a common adverse event during sedated hysteroscopy for assisted reproduction, and it is more likely to occur in overweight or obese patients.
- Conditions
- Hypoxia, Hysteroscopy, Overweight or Obesity
- Trial name
- EROP (NCT06004843)
- Testing
- remimazolam, Propofol
- Where
- China
- Volunteers
- 600 people
- Sponsor
- RenJi Hospital
Sedation During Spinal Anesthesia
Sedation During Spinal Anesthesia
Patients during spinal anesthesia should be sedated.
- Trial name
- NCT03133780
- Testing
- Ketamine, Midazolam
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Epilepsy, Seizure
Pro-Epileptic Effects of IV Ketamine
The investigators evaluated the safety and potential pro-epileptic effects of intravenous (IV) ketamine during procedural sedation in comparison with IV midazolam and IV propofol.
- Trial name
- Ketamin stdy (NCT06741930)
- Testing
- Ketamine, Midazolam, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Haseki Training and Research Hospital
Anesthesia, Pain
Memory & Conditioning Under Anesthesia
The purpose of this study is to determine the effects of pain on long-term memory and conditioned physiologic responses in the presence and absence of distinct intravenous anesthetics.
- Trial name
- MCA (NCT04062123)
- Testing
- Dexmedetomidine, Propofol, Fentanyl
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Keith M Vogt
Colonoscopy
Propofol and Dexmedetomidine Versus a Propofol Only Regimen for Sedation During Colonoscopy
An ideal sedative for colonoscopy should have properties that include: rapid onset and offset of action, provide cardiopulmonary stability, have minimal adverse effects, and allow for smooth recovery, and early discharge.
- Trial name
- NCT03139279
- Testing
- Dexmedetomidine, Propofol
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- State University of New York - Downstate Medical Center
Capnography
The Effect of Oxygen Flow Rate on End-tidal CO2 During Deep Sedation
This study aims to detect the effect of different O2 flow rates on end tidal carbon dioxide level in patients scheduled for minor gynaecological procedures under deep sedation using laryngeal mask airway.
- Trial name
- NCT06824610
- Testing
- capnography
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Minia University
Gastric Ulcer, Gastric Cancer
Hypoxia During Gastroenterological Endoscope Procedures Sedated With Ciprofol In Overweight Or Obesity Patients
Ciprofol is a new general anesthetic, which combine with γ- Aminobutyric acid-a (GABAA) receptor. Ciprofol has shown equivalent anesthetic efficacy of propofol at 1/4 to 1/5 of the dosage.
- Conditions
- Gastric Ulcer, Gastric Cancer, Gastrointestinal Polyp
- Trial name
- SpO2 (NCT05518929)
- Testing
- Ciprofol, Propofol
- Where
- 5 sites in China
- Volunteers
- 1,090 people
- Sponsor
- RenJi Hospital