Clinical trials: Sedation During
Conscious Sedation, Propofol
Personalized Music and Dreaming During Propofol Sedation
Many patients report dreams during intravenous (IV) propofol sedation, but it is uncertain whether listening to music changes how often dreams occur or how pleasant they feel.
- Conditions
- Conscious Sedation, Propofol, Dreams
- Trial name
- NCT07389954
- Testing
- Preferred Music, Matched Non-Preferred Music, Silence (Headphones Only)
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Wonkwang University Hospital
Bronchoscopy, Anesthesia
An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Flexible Bronchoscopy
Very often patients receive medication before a diagnostic, therapeutic, or surgical procedure to help them relax, keep them calm, and to relieve them from pain. This is called procedural sedation.
- Trial name
- NCT00306722
- Testing
- AQUAVAN® (fospropofol disodium) Injection
- Where
- 25 sites in United States
- Volunteers
- 250 people
- Sponsor
- Eisai Inc.
Autism Spectrum Disorder
Procedure Sedation With Dexmedetomidine in Children With Autism Spectrum Disorders During Magnetic Resonance Imaging
Autism spectrum disorders (ASD) is a neurodevelopmental disorder and is characterized by functional impairment in social communication, restricted interests, and repetitive behaviors.The children with ASD has been shown different…
- Trial name
- NCT03597477
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Colonoscopy, Colonic Polyps
Study of AQUAVAN® Injection (AQUAVAN; Fospropofol Disodium) for Sedation During Colonoscopy
Very often, patients receive sedative medication before a diagnostic, therapeutic, or surgical procedure to help them relax, keep them calm, and to relieve them from pain. This is called procedural sedation.
- Trial name
- NCT00125424
- Testing
- AQUAVAN® (fospropofol disodium) Injection, Midazolam HCl
- Where
- 20 sites in United States
- Volunteers
- 125 people
- Sponsor
- Eisai Inc.
Sedation
Clinical Study to Investigate the Efficacy and the Safety of DA-9501 in Sedation During the Surgery or Medical Procedure Without Intubation
The purpose of this study is to evaluate the efficacy and the safety of DA-9501 (Dexmedetomidine) in sedation during the surgery or medical procedure without intubation under monitored sedation care.
- Trial name
- NCT01438931
- Testing
- DA-9501
- Where
- 18 sites in Japan
- Volunteers
- 162 people
- Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
Sedation in Non-intubated Diagnostic and Therapeutic Procedures, Sedation
Efficacy and Safety of Nasopharyngeal Tube During Sedation
The goal of this randomized controlled study is to determine whether nasopharyngeal tube oxygenation could increase the fraction of inspired oxygen compared with standard oxygen during a sedated procedure with spontaneous…
- Trial name
- NCT07880002
- Testing
- nasopharyngeal tube, regular cannula
- Volunteers
- 160 people
- Sponsor
- International Peace Maternity and Child Health Hospital
Opioid Use, Unspecified, Remifentanil
Anesthesia for Vascular Access Devices
Our aim was to investigate whether remifentanil use in both infusion and bolus techniques could provide sufficient sedation and analgesia without serious adverse effects for central venous access device procedures under monitored…
- Conditions
- Opioid Use, Unspecified, Remifentanil, Sedation Complication, Analgesia
- Trial name
- NCT04749069
- Testing
- Comparison of pain intensity rating scale
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Atrial Fibrillation (AF), Catheter Ablation
Effects of Music During Atrial Fibrillation Ablation Under Conscious Sedation
I. Background Atrial fibrillation, a common type of arrhythmia, is often treated with radiofrequency catheter ablation, a minimally invasive procedure that helps restore a normal heart rhythm.
- Conditions
- Atrial Fibrillation (AF), Catheter Ablation, Pain Management
- Trial name
- NCT06953752
- Testing
- Music intervention, Control
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shaoxing People's Hospital
Mental Function
Ultrasonic Deep Brain Stimulation During Anesthetic Sedation
The purpose of this study is to see if mental functions take place during different levels of anesthesia. The researchers expect to gain a deeper understanding of mental function during different levels of anesthesia, and to…
- Trial name
- NCT05495945
- Testing
- Low-intensity focused ultrasound pulsation (LIFUP), Functional Magnetic Resonance Imaging (fMRI) using Propofol
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Hypoxia, Infertility
The Efficacy of Remimazolam on Incidence of Hypoxia During Sedated Transvaginal Oocyte Retrieval
Hypoxia is the most common adverse reaction during sedation outside the operating room.Exploring novel drug combinations to reduce the incidence of hypoxia during sedation in patients undergoing transvaginal oocyte retrieval…
- Conditions
- Hypoxia, Infertility, Infertility Assisted Reproductive Technology
- Trial name
- NCT07335536
- Testing
- remimazolam-alfentanil combination, propofol-alfentanil
- Where
- 2 sites in China
- Volunteers
- 400 people
- Sponsor
- Diansan Su
Conscious Sedation During Endoscopic Retrograde Choledochopancreatography
Efficacy of Oxycodone-propofol Combination Compared With a Fentanyl-propofol Combination on Conscious Sedation Effect and Early Cognitive Function During Therapeutic Endoscopic Retrograde Cholangio-pancreatography
To evaluate and compare the sedative effect and effects on early period cognitive function of a fentanyl-propofol Combination (FP) regimen with a oxycodone-propofol(OP) combination during the endoscopic retrograde…
- Trial name
- NCT03755609
- Testing
- Oxycodone, fentanyl
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Changhai Hospital
Sedation for Diagnostic Gastroscopy
Remimazolam Versus Midazolam for Sedation During Upper GI Endoscopy: a Randomized Controlled Trial
Rationale Midazolam is known for its safety, effectiveness for procedural sedation during gastrointestinal (GI) endoscopy and is used as standard sedative by endoscopists worldwide.
- Trial name
- REST (NCT06614036)
- Testing
- Remimazolam, Midazolam
- Where
- 3 sites in Netherlands
- Volunteers
- 148 people
- Sponsor
- Koen Munters
Acute Ischemic Stroke
Individualized Blood Pressure Management During Endovascular Stroke Treatment
Optimal blood pressure management during endovascular treatment of acute ischemic stroke is not well established. Several retrospective data indicate, that there is a U-shaped relationship of admission blood pressure and…
- Trial name
- INDIVIDUATE (NCT04578288)
- Testing
- INDIVIDUALIZED BLOOD PRESSURE MANAGEMENT DURING ENDOVASCULAR TREATMENT OF ACUTE ISCHEMIC STROKE UNDER PROCEDURAL SEDATION
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- University Hospital Heidelberg
Gastric Cancer, Intestinal Cancer
HFNO Reduces Hypoxia During Sedated Gastroscopy or Colonoscopy in High Risk Patients
The objective of this study is to observe the preventive effects of high flow nasal oxygenation on the incidence of hypoxia during gastroscopy or colonoscopy sedated with propofol in high-risk patients.
- Conditions
- Gastric Cancer, Intestinal Cancer, Intestine Adenoma, Gastritis
- Trial name
- HRISK (NCT05510388)
- Testing
- High-flow nasal cannula oxygenation, Regular nasal cannula oxygenation
- Where
- 2 sites in China
- Volunteers
- 450 people
- Sponsor
- RenJi Hospital
Endoscopy, Gastrointestinal, Sedation, Conscious
Development of an Algorithm to Denoise HFNO-generated Tracheal Sound
This study aims to develop an algorithm to mitigate the noise generated by the high-flow nasal oxygen system for tracheal sound monitoring in deeply sedated patients.
- Trial name
- NCT06218017
- Testing
- High flow nasal oxygen fist, High flow nasal oxygen later
- Where
- 2 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Failed Conscious Sedation During Procedure
Controlled Sedation for Cataract Surgery
This study evaluates the surgeon and patient´s satisfaction who undergoes cataract surgery using either dexmedetomidine or remifentanil as sedation
- Trial name
- NCT03401606
- Testing
- remifentanil, Dexmedetomidine
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Fundación Universitaria de Ciencias de la Salud
Postoperative Pain, Objective Assessment of Sedation
Infrared Pupillometry During General Anesthesia to Predict Pain
The study comprises of a series of pupillary measurements using infrared pupillometry in patients undergoing arthroscopic knee surgery of any type.
- Trial name
- NCT02058511
- Testing
- Anesthesia Premedication, Induction and Maintenance, Pupillometry after administration of anesthetic drugs
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, San Francisco
Lumbar Disc Disease, Radiculopathy Lumbar
Patient Satisfaction During Lomber Transforaminal Epidural Steroid Injection: The Role of Sedation, Anxiety, and Pain
Transforaminal epidural steroid injection (TFESI) is a minimally invasive procedure commonly used for the management of lumbar radicular pain.
- Conditions
- Lumbar Disc Disease, Radiculopathy Lumbar, Radicular Pain
- Trial name
- NCT07495501
- Testing
- Fluoroscopy-guided lumbar transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Mersin University
Hypoxemia
Procedural Oxygen Mask vs. Nasal Cannula for Hypoxemia Prevention During Endoscopic Retrograde Cholangiopancreatography
Endoscopic retrograde cholangiopancreatography (ERCP) is an imaging procedure that visualizes the drainage ducts of the pancreas, gallbladder, and liver through the use of a duodenoscope and contrast media.
- Trial name
- NCT06681558
- Testing
- Group Nasal Cannula, Group Procedural Oxygen Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Kocaeli City Hospital
Sedation Complication, Obesity
Effect of HFNO on Spontaneous Ventilation in Obese Patients During Analgo-sedation for Vitrectomy
Patients suffering from pathology of posterior eye chamber such as diabetic retinopathy, retinal detachment, traumatic eye injury, retained lens fragments, macular hole, pucker, dislocated intraocular lens after cataract surgery…
- Conditions
- Sedation Complication, Obesity, Hypoxic Respiratory Failure, Airway Obstruction, Nasal
- Trial name
- NCT04049240
- Testing
- Device: low-flow nasal oxygenation (LFNO) 18<BMI<30 kg/m2, Device: low-flow nasal oxygenation (LFNO) 30≤BMI<35 kg/m2, Device: low-flow nasal oxygenation (LFNO) BMI≥35 kg/m2
- Where
- Croatia
- Volunteers
- 126 people
- Sponsor
- University of Split, School of Medicine