Clinical trials: Sedation During
Conscious Sedation Failure During Procedure
Ketamine Tolerance in Children After Repeated Administrations During Radiotherapy Sessions
Ketamine provides a safety zone for sedated but spontaneously ventilated children especially in remote conditions such as radiotherapy units where sedation is an essential practice for children to keep calm and motionless In this…
- Trial name
- NCT02512055
- Testing
- Ketamine
- Volunteers
- 33 people
- Sponsor
- Baskent University
Surgery, Hypoventilation
A Comparison of the Detection of Hypoventilation During Deep Sedation Utilizing Nasal End Title CO@ Versus Transcutaneous CO2 Measurement Techniques
The estimation of the partial pressure of carbon dioxide (PCO2) in the arterial blood is used to judge the adequacy of ventilation during spontaneous and controlled ventilation.
- Trial name
- NCT00954733
- Testing
- Arterial blood draw
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwestern University
Apnea During Procedural Sedation
Electric Blower Based Ventilator Used During Procedural Sedation
Conduct human trials in the endoscopy suite of our continuous positive airway pressure (CPAP) ventilator approach using an FDA approved ventilator.
- Trial name
- NCT02621463
- Testing
- Noninvasive Ventilator (V60, Philips)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Utah
Dental Care for Children
Evaluation Ofe the Anxiolytic Effect of EMONO in Children During Dental Care (MOPEA)
The EquiMolar Oxygen and Nitrous Oxyde mix (EMONO) is listed by the ANSM (National Agency for the Safety of Medicines and Health Products) as drugs with enhanced surveillance.
- Trial name
- MOPEA (NCT03998774)
- Testing
- Evaluate the anxiolytic effect during dental care with MEOPA in children
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Nantes University Hospital
Procedural Sedation, Gastrointestinal Endoscopy
SED Pack: Safety and Performance of a Medical Device Software for Predictive Monitoring During Sedation
The SED-PACK study is a prospective, observational, single-center clinical investigation evaluating the clinical performance and safety of SED Pack, a Medical Device Software (MDSW) developed by Predictheon Medical S.L., in a…
- Trial name
- NCT07749781
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Predictheon Medical, S.L.
Stroke, Anesthesia
"GOLIATH" - General Or Local Anaestesia in Intra Arterial THerapy
Patients suffering a stroke with a large vessel occlusion is often treated intra veneous thrombolyse and on top of that also intra arterial therapy. It is unknown what form of anaestesia is best during intra arterial therapy.
- Conditions
- Stroke, Anesthesia, Cerebral Revascularization
- Trial name
- GOLIATH (NCT02317237)
- Testing
- Local anesthesia
- Where
- Denmark
- Volunteers
- 128 people
- Sponsor
- University of Aarhus
Colonoscopy
Effects of Intravenous Lidocaine During Sedation for Colonoscopy.
This study assesses the benefits of continuous intravenous lidocaine administration during sedation for colonoscopy. Sedation will consist of propofol infusion titrated to provide adequate working conditions to the…
- Trial name
- NCT02784860
- Testing
- Lidocaine, normal saline
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Liege
Esophagogastroduodenoscopy
Meperidine as the Single Sedative Agent During Esophagogastroduodenoscopy
Upper endoscopy is uncomfortable for most patients. Meperidine has both sedative and analgesic effects, so its use may be helpful for patients receiving upper endoscopy.
- Trial name
- NCT01547520
- Testing
- Meperidine, normal saline
- Where
- Taiwan
- Volunteers
- 140 people
- Sponsor
- Dalin Tzu Chi General Hospital
Pain
Remifentanil Versus Propofol for TCI Sedation of Patients Undergoing Gastrointestinal Endoscopic Procedures
The purpose of this study was to compare remifentanil and propofol for sedation of patients during endoscopic gastrointestinal procedures.
- Trial name
- NCT01746641
- Testing
- Remifentanil, Propofol
- Where
- Colombia
- Volunteers
- 69 people
- Sponsor
- Fundación Universitaria de Ciencias de la Salud
Pain
Safety and Efficacy of Intravenous (IV) Dexmedetomidine During Flexible Bronchoscopy and Endobronchial Ultrasound
To achieve safe,consistent, continuous sedation using Dexmedetomidine in advaced bronchoscopy procedures that may reduce the need for rapid pain sedative infusion.
- Trial name
- NCT00691886
- Testing
- dexmedetomidine hydrochloride
- Where
- United States
- Sponsor
- Lahey Clinic
Gastro-Intestinal Disorders
Effects of Passive Smoking on Children During Gastrointestinal Endoscopy
To evaluate the effect of passive smoking in children during Gastrointestinal Endoscopy.
- Trial name
- NCT03920046
- Testing
- Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 518 people
- Sponsor
- TC Erciyes University
Pain
Analgesia During Pediatric Digestive Endoscopy: a Comparison of Two Protocols for Procedural Sedation
The purpose of this study is to determine whether ketamine, midazolam, and meperidine are more effective than midazolam and meperidine alone for procedural sedation and analgesia in pediatric digestive endoscopy.
- Trial name
- NCT01168492
- Testing
- ketamine
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Université de Montréal
Deep Sedations, Conscious Sedation
Comparison of Safety and Efficacy for Different Sedation Regimens During Colonoscopy
This is a randomized, double-blinded, prospective study which will be conducted at the Department of Gastroenterology, King Saud Hospital, Unaizah, Qassim, Saudi Arabia.
- Conditions
- Deep Sedations, Conscious Sedation, Colonoscopy
- Trial name
- NCT06763705
- Testing
- Midazolam, Propofol, Fentanyl
- Where
- Saudi Arabia
- Volunteers
- 183 people
- Sponsor
- Qassim Health Cluster
Morbid Obesity
Sedation of Morbidly Obese for Balloon Insertion
This prospective study will assess the value of different supplements to orpofol bases anesthesia in morbidly obes e patients scheduled for balloon insertion.
- Trial name
- SedBaloon (NCT03747094)
- Testing
- Fentanyl, Ketamine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Children Requiring Sedation for MRI/CT
The Incidence and Nature of Adverse Events During Pediatric Sedation for MRI/CT in One Korean University Hospital: Retrospective Study
Sedation and anesthesia for diagnostic imaging represents a rapidly growing field of practice, especially in children. Propofol is the most common sedative drug administered for MRI/CT.
- Trial name
- NCT01855581
- Testing
- pediatric sedation (propofol, ketamine, etc)
- Where
- South Korea
- Volunteers
- 3,739 people
- Sponsor
- Yonsei University
Scheduled Gastroscopy Under Sedation
Endoscopist and Endoscope Motions During Digestive Endoscopy
The aim of the study is to record and analyze endoscopist and endoscope motions to identify key movements in flexible endoscopy.
- Trial name
- EndoMouv (NCT03458403)
- Testing
- Motions during gastroscopy
- Where
- France
- Volunteers
- 23 people
- Sponsor
- IHU Strasbourg
Deep Sedation
Airway Management During Deep Sedation in Hysteroscopy
Hysteroscopy is used to examine and treat uterine diseases. Because of severe pain due to uterine distention and cervical dilatation, deep sedation usually be provided during this procedure.
- Trial name
- NCT05701839
- Testing
- face mask ventilation, nasopharyngeal tube ventilation, oxygen saturation monitoring
- Where
- China
- Volunteers
- 400 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Laceration of Skin
IN Ketamine vs IN Midazolam and Fentanyl for Laceration Repair
Often, repair of the cuts (laceration repair) proves to be traumatic for the children and the parents. Nasal spray (Intranasal/IN) approaches for procedural pain reduction, such as during dental work, have been demonstrated to…
- Trial name
- NCT03528512
- Testing
- Ketamine, Midazolam and fentanyl
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Corewell Health East
Lacerations
A Randomized, Clinical Trial of Oral Midazolam Versus Oral Ketamine for Sedation During Laceration Repair.
Sedation is often needed for young children undergoing minor procedures in the emergency department (ED). Oral midazolam is one of the most commonly used regimens for children undergoing laceration repair but its sedative…
- Trial name
- NCT01925898
- Testing
- Midazolam - active comparator, Experimental Arm: Ketamine
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Assaf-Harofeh Medical Center
Kyphoplasty, Prone Position
TCI Versus Manual TIVA for Sedation During Prone Kyphoplasty: Effects on Respiration, Recovery, and EEG
This single-center, prospective, observational study compares target-controlled infusion (TCI) versus manually administered total intravenous anesthesia (TIVA) for sedation in patients undergoing kyphoplasty in the prone…
- Conditions
- Kyphoplasty, Prone Position, Target Controlled Infusion of Propofol, End Tidal Carbon Dioxide
- Trial name
- NCT07745348
- Testing
- Target controlled infusion of propofol, non invasive ETCO2 monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital