Clinical trials: Sedation During
Obesity
Balanced Propofol Sedation During Upper Endoscopy in Morbidly Obese Patients
The purpose of this study is to evaluate the safety of propofol-based, gastroenterologist-administered sedation in severely obese patients (BMI≥35) undergoing upper endoscopy.
- Trial name
- NCT00782873
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Research Associates of New York, LLP
Fertilization in Vitro
Interest of Audiovisual Distraction in the Management of Anxiety and Pain During Oocyte Retrieval
Oocyte retrieval procedure for in vitro fertilization is a source of anxiety for patients. Local anaesthesia or sedation are commonly used to manage many situations of anxiety, including the oocyte retrieval.
- Trial name
- Happy-Fiv (NCT04213781)
- Testing
- HappyMed Video Glasses, Propofol, Sufentanil
- Where
- France
- Volunteers
- 36 people
- Sponsor
- CMC Ambroise Paré
Chronic Subdural Hematoma
Propofol Target-Controlled Infusion Versus Dexmedetomidine for Sedation During Chronic Subdural Hematoma Surgery Under Local Anesthesia
Chronic subdural hematoma is a collection of old blood on the surface of the brain that mainly affects older adults. It is often treated by draining the blood through a small hole in the skull (burr hole), under local anesthesia…
- Trial name
- NCT07912203
- Testing
- Dexmedetomidine, Propofol (Astra-Zeneca)
- Volunteers
- 60 people
- Sponsor
- National Institute of Neurology, Tunisia
Ventilatory Status of Deeply Sedated ERCP Patients
Quantitive And Qualitive Assessment Of The Oxygen Delivery And EtCO2 Sampling With The Smart Bite Block Mark III During An Upper Endoscopic Procedure Under Sedation
The study hypothesis is that a modified smart bite block system can deliver up to 10 liters/minute of supplemental oxygen orally with the CO2 monitoring performance substantially equivalent to the currently marketed smart bite…
- Trial name
- NCT00814424
- Testing
- monitored using currently marketed smart biteblock o2, monitored using investigational smart biteblock
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Hadassah Medical Organization
Biliary Tract Diseases, Procedural Sedation and Analgesia
Esketamine Versus Sufentanil for Sedation in Patients Undergoing ERCP
This study compares two anesthesia medications, esketamine and sufentanil, used together with propofol during ERCP procedures. The goal is to find out which combination provides better safety and comfort for people undergoing…
- Trial name
- ES-ERCP (NCT07702240)
- Testing
- Esketamine, Sufentanil
- Volunteers
- 530 people
- Sponsor
- Ren Da
Epilepsy
Conscious Sedation for Epilepsy Surgery
Sixty patients were randomly allocated into two groups, group PD and group PR, thirty patients in each group. Patients in PD group received propofol and dexmedetomidine intravenous infusion and patients in PR group received…
- Trial name
- NCT02988050
- Testing
- Remifentanil, Dexmedetomidine, Propofol
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Choledocholithiasis, Cholangiocarcinoma
Etomidate vs. Midazolam for Sedation During ERCP
Recently up-coming drug, etomidate which is a modulator of GABA(gamma-Aminobutyric acid)-A receptor has been known that it maintains the appropriate sedative levels and affects little effects on respiratory system.
- Conditions
- Choledocholithiasis, Cholangiocarcinoma, Pancreatitis, Pancreatic Cancer
- Trial name
- NCT02027311
- Testing
- Etomidate, Midazolam, Meperidine
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Cheju Halla General Hospital
Conscious Sedation
Magnesium Sulphate Versus Fentanyl for Conscious Sedation in CSDH
The investigators hypothesize that magnesium sulphate owing to its analgesic and sedative properties is not inferior to fentanyl in providing conscious sedation as adjuvants to propofol and local injection of lidocaine in…
- Trial name
- CSDH (NCT03548493)
- Testing
- Magnesium sulphate, Fentanyl, Propofol
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Kasr El Aini Hospital
Lower Back Pain, Lumbar Radiculopathy
Virtual Reality as a Substitute for Procedural Sedation During Epidural Steroid Injections
This study examines the impact of virtual reality compared to sedation (midazolam and/or fentanyl) and no intervention on pain experienced from an epidural steroid injection (ESI).
- Trial name
- NCT04887285
- Testing
- Virtual reality, Intravenous sedation, Standard care
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Johns Hopkins University
Colonoscopy
Virtual Reality Alternative to Pharmacological Sedation During Colonoscopy
Colonoscopy patients will be fitted with a virtual reality head-mounted display, and virtual experiences will be initiated prior to colonoscope insertion. Colonoscopy will be initiated without standard sedatives and narcotics.
- Trial name
- NCT04349150
- Testing
- Virtual reality
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Nociceptive Pain
Comparison of Different Objective Nociceptive Measurement Methods During Surgery
Traditionally, hemodynamic response e.g. pulse and blood pressure are used to evaluate pain in humans who are anesthetized. These values, however, can be affected by factors other than pain response .
- Trial name
- NCT05218551
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Göteborg University
Peripheral Arterial Disease
Impact of Virtual Reality on Patient Pain During Lower Limb Revascularization Via Endovascular Surgery Under Local Anesthesia With Sedation
The prevalence of peripheral arterial disease (PAD) increases with age In addition to medical treatment, endovascular procedures can be performed, depending on the stage of the disease, to prevent complications and/or sequelae…
- Trial name
- REVDOU (NCT07181434)
- Testing
- The patient will be equipped with VR headsets
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Poitiers University Hospital
Colonoscopy, Sedation
Non-pharmacological Intervention for Colonoscopy
The purpose of this study is to determine whether a non-pharmacological intervention reduces consumption of sedative drugs during colonoscopy. A reduction of sedative drugs may reduce side effects.
- Conditions
- Colonoscopy, Sedation, Hypnosis
- Trial name
- NCT00913861
- Testing
- hypnosis, standard sedation, Structured attention
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University Hospital, Geneva
Procedural Sedation
Dexmedetomidine and Midazolam Nebulization as Sedation During Cesarean Delivery in Pre-eclampsia
Null hypothesis: There is no difference between the effects of nebulization of dexmedetomidine and midazolam as procedural sedation during cesarean delivery under spinal Anesthesia in pre-eclamptic parturients Alternative…
- Trial name
- NCT04873596
- Testing
- Nebulized dexmedetomidine, Nebulized midazolam
- Where
- Egypt
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Analgesic Effects of Music
The Sedative Effects of Music Listening on Pain During Cold Pressor Test
This study aims to understand whether listening to music can reduce pain and anxiety caused by a cold-temperature stimulus in healthy young adults (n = 30).
- Trial name
- ESEMP (NCT07515196)
- Testing
- Phase 1 - Silence (Baseline), Phase 2 - Happy Mode with Measured Rhythm, Phase 3 - Sad Mode with Measured Rhythm
- Where
- Lebanon
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rawane El Dimachki
Chronic Obstructive Pulmonary Disease, Respiratory Failure
High Flow Nasal Cannula Oxygen During Sedation for Video-assisted Thoracoscopic Surgery
High-flow nasal cannula (HFNC) is a device that delivers10 to 70 L min-1 of heated, humidified 100% oxygen via nasal route. It provides positive airway pressure, decreases dyspnea, decreases the work of breathing, and improves…
- Trial name
- NCT04520568
- Testing
- High flow nasal cannula, CONTROL
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Laryngoscopy, Child
Correlation Between Sedation Depth Monitoring and Reflexes During Intravenous Anesthesia With Dexmedetomidine and Remifentanil in Children Undergoing Direct Laryngoscopy for Surgical Procedures
This study evaluates the correlation between sedation depth monitoring obtained by NeuroSENSE ® NS 701 Monitor and reflexes during intravenous anesthesia in children undergoing direct laryngoscopy for surgical procedures.
- Conditions
- Laryngoscopy, Child, Monitoring
- Trial name
- NCT03426579
- Testing
- NeuroSENSE ®in children
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- University Hospital, Antwerp
Patients Need Upper Gastrointestinal Endoscopy, Peptic Ulcer
Adverse Events During Upper Gastrointestinal Endoscopy
The primary objective is to investigate the adverse events during upper gastrointestinal endoscopy with and without sedation in Chinese population
- Conditions
- Patients Need Upper Gastrointestinal Endoscopy, Peptic Ulcer, Gastric Cancer, Esophagus Cancer
- Trial name
- AEDUGESSH (NCT01979549)
- Where
- 3 sites in China
- Volunteers
- 6,000 people
- Sponsor
- RenJi Hospital
Hypoxemia, Conscious Sedation
Impact of Nasal Mask Versus Nasal Cannula Oxygenation on Hypoxemia in Gastrointestinal Endoscopy: A Brain Function Monitoring (SedLine)-Guided Randomized Controlled Trial (NAMSHIC)
This randomized controlled trial compared the efficacy of a nasal mask versus a standard nasal cannula for oxygen delivery during gastrointestinal endoscopic procedures performed under target controlled propofol infusion…
- Trial name
- NAMSHIC (NCT07500779)
- Testing
- Nasal Mask Oxygenation, Nasal Cannula Oxygenation
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Anesthesia, Sedation
EEG Signal Correlates During Anesthesia and Sedation in Adults and Children
This prospective, multicenter, non-interventional observational study investigates the correlates between electroencephalographic (EEG) signals and pharmacological/clinical parameters during general anesthesia and procedural…
- Conditions
- Anesthesia, Sedation, Consciousness Monitors
- Trial name
- SPECTRALADUPED (NCT07460414)
- Where
- 2 sites in France
- Volunteers
- 330 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris