Clinical trials: Sedation During
Upper Gastrointestinal Endoscopy, Anesthesia
Efficacy of Propofol Combination With Either Ketamine, Dexmedetomidine or Midazolam for Sedation During Upper Gastrointestinal Endoscopic Procedures
The investigators are comparing the efficacy of three different sedative agents in gastrointestinal endoscopic procedures.
- Trial name
- NCT07190612
- Testing
- Dexmedetomidine and propofol, Midazolam and propofol, ketamine and propofol
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Healthy Volunteers
Induction of Dreaming With EEG and Anesthesia in Healthy Adults
This open-label, randomized crossover study in healthy adults tests two propofol protocols to produce distinct experiential states.
- Trial name
- IDEA (NCT07198711)
- Testing
- Propofol - Emergence-from-LOR Protocol, Propofol - Light Sedation Protocol
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Stanford University
Patients Undergoing Endoscopic Retrograde Cholangiopancreatography in Prone Position
A Trial Comparing High-flow Nasal Oxygen With Standard Management for Conscious Sedation During Endoscopic Retrograde Cholangiopancreatography in Prone Position
Traditional conscious sedation for endoscopic retrograde cholangiopancreatography in prone position places patients at risk of desaturation, and high-flow nasal oxygen may reduce the risk.
- Trial name
- NCT03872674
- Testing
- high-flow humidified oxygen-delivery system (OptiFlow THRIVE)
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Yonsei University
Lung Diseases, Diagnosis
Dexmedetomidine-ketamine Combination Versus Fentanyl-midazolam During Bronchoscopy
Sedation during flexible bronchoscopy (FB) should maintain an adequate respiratory drive, ensure maximum comfort for the patient, and warrant that the objectives of the procedure are achieved.
- Conditions
- Lung Diseases, Diagnosis, Anesthesia
- Trial name
- NCT06185127
- Testing
- Dexmedetomidine, Ketamine, Midazolam
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- University of Patras
Reality Device, Reduction Procedure
Pilot Study on the Evaluation of the Effectiveness of a Virtual Reality Device on Anxiety During Procedural Sedation in Traumatology in Emergency Department
The aim of this study is to evaluate the efficiency of a reality device and a virtual hypnosis software to reduce the anxiety during reduction procedure in traumatology in an emergency department.
- Conditions
- Reality Device, Reduction Procedure, Fracture, Dislocation
- Trial name
- VIRTUAL DREAM (NCT04936880)
- Testing
- Experimental : Virtual reality + analgesia-sedation, Control: Analgesia-sedation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Poitiers University Hospital
Spine, Minimally Invasive
Hand Holding During Light Sedation for Minimally Invasive Spine Surgery Improves Outcomes
The investigators want to determine whether handholding improves patient satisfaction and reduce patient's anxiety during minimally invasive outpatient spine surgery with monitored anesthesia care.
- Trial name
- HHLS (NCT05058079)
- Testing
- Intraoperative Hand Held
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Rhode Island Hospital
Capnography as an Adjunct to Standard Monitoring During Midazolam and Propofol Sedation for Interventional Upper GI Endoscopy
Capnography During Upper GI Endoscopy
In this randomized controlled trial the utility of capnography and IPI gets evaluated. Hypoxemia may occur during sedation with midazolam and propofol.
- Trial name
- NCT01242345
- Testing
- Capnography
- Where
- 3 sites in Germany
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Pediatric, Gastroscopy
Effect of Esketamine on 95% Induction Dose of Remimazolam
As an invasive operation, gastroscopy will cause children's nervousness, anxiety and uncooperative behavior, and even lead to the risk of bleeding and perforation, which will also affect the accuracy of the examination…
- Conditions
- Pediatric, Gastroscopy, ED95, Sedation
- Trial name
- EEIDR (NCT06303037)
- Testing
- Remimazolam besylate and low-dose Esketamine, Remimazolam besylate and Medium dose Esketamine
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Pain
Nitrous Oxide for Analgesia During Colonoscopy
The purpose of the study is to determine the analgetic effect of nitrous oxide during colonoscopy, compared to no sedation and intravenous (IV) sedation.
- Trial name
- NCT00318825
- Testing
- Nitrous oxide
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Rikshospitalet University Hospital
Sedation, Cataract
Comparison of Two Sedation Versus Placebo Techniques During Cataract Surgery Under Local Anesthesia
Check the sedation conditions during topic cataract surgery
- Trial name
- NCT04149340
- Testing
- Cataract surgery
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- University of Liege
Anxiety
Audiovisual Distraction in Intensive Care
Resuscitation patients are subject to constant stress of multifactorial origin: their state of health, the noisy environment of critical care, the multiple examinations and care provided, lack of sleep, stress from their loved…
- Trial name
- DARE (NCT07013877)
- Testing
- RELAX glasses
- Volunteers
- 456 people
- Sponsor
- Centre Hospitalier de Valenciennes
Complications
Thiopental Versus Propofol During Magnetic Resonance Imagining in Children: Something Old, Something New
Magnetic resonance imagining (MRI) in children requires sedation to achieve the degree of cooperation or immobilization, necessary to complete these procedures successfully.
- Trial name
- NCT01318044
- Testing
- Propofol and Thiopental
- Where
- Albania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Clinical Centre of Kosova
Duchenne Muscular Dystrophy
Sedation During Muscle Biopsy in Patients With Duchenne Muscular Dystrophy
This is an interventional study on Duchenne muscular dystrophy patients who will be receiving sedation for a muscle biopsy as part of another study.
- Trial name
- NCT01645098
- Testing
- Ketamine, Dexmedetomidine
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Nationwide Children's Hospital
Airway Obstruction, Sedation Complication
Evaluation of Medical Device for Airway Patency During Sedation (SW01-2022)
The goal of this four-part preclinical [I-II] and clinical [III-IV] trial is to compare, with randomised crossover study design [I-IV], a new medical airway device with standard procedure (biteblock or no device) for upper airway…
- Conditions
- Airway Obstruction, Sedation Complication, Safety Issues, Patient Satisfaction
- Trial name
- NCT05708651
- Testing
- Investigational device [I-IV], Comparator [I-IV]
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Stairway Medical AB
Endometritis, Tuberculous Endometritis
HFNO Reducing the Incidence of Hypoxia for Hysteroscopy Sedated With Propofol
To determine whether high-flow nasal cannula oxygen can reduce the incidence of hypoxia during the procedure of sedated hysteroscopy.
- Conditions
- Endometritis, Tuberculous Endometritis, Subseptate Uterus, Endometrial Polyps
- Trial name
- NCT05049395
- Testing
- High Flow Nasal Cannula oxygen (HFNO), Regular oxygen
- Where
- China
- Volunteers
- 960 people
- Sponsor
- RenJi Hospital
Loss of Consciousness
Sufentanil Bispectral Index Elderly
We compared BIS values during propofol stepwise induction with or without concomitant sufentanil in patients ≥ 65 years .
- Trial name
- NCT02831101
- Testing
- Sufentanil
- Volunteers
- 71 people
- Sponsor
- University Hospital, Geneva
Endoscopic Retrograde Cholangiopancreatography
Randomized Controlled Study for Analyzing Clinical Benefit of Pain Focused Sedation With Combination of Fentanyl and Propofol During Endoscopic Retrograde Cholangiopancreatography (ERCP)
The investigators study is the randomized controlled study for analyzing clinical benefit of pain focused sedation with combination of fentanyl and propofol during Endoscopic retrograde cholangiopancreatography (ERCP).
- Trial name
- NCT01840371
- Testing
- Conventional sedation, Experimental sedation
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Yonsei University
Benign Prostate Hypertrophy(BPH)
Trial to Assess the Efficacy and Safety During Convective Radiofrequency Water Vapor Thermal Therapy (REZUM) for Benign Prostate Hyperplasia
The primary aim of the study is to show that methoxyflurane-lorazepam-percocet combination administrated 'per os' is non inferior to deep intravenous sedation in achieving analgesia during Rezum convective radiofrequency water…
- Trial name
- NCT07017452
- Testing
- Methoxyflurane - Penthrox, Control, Percocet Pill
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Gastrointestinal Endoscopy, Sedation
Bispectral Index Monitoring of Sedation During Endoscopic Retrograde Cholangiopancreaticography
This randomized study investigates the benefits of an additional Bispectral Index monitoring of depth of sedation during endoscopic retrograde cholangiopancreaticography.
- Trial name
- EndoBISs (NCT00952458)
- Testing
- BIS monitoring
- Where
- Germany
- Volunteers
- 144 people
- Sponsor
- Technical University of Munich
Deep Sedation, High Flow Nasal Canula
HFNO Flow Rates and Cerebral Oxygenation During Deep Sedation for Cystoscopy
For Patients and Families This study aims to investigate how high-flow oxygen therapy affects oxygen levels, especially brain oxygenation, during cystoscopy procedures performed under sedation.
- Conditions
- Deep Sedation, High Flow Nasal Canula, Cerebral Oxygenation, PSI
- Trial name
- NCT07630038
- Testing
- High-Flow Nasal Oxygen 40 L/min (HF40), High-Flow Nasal Oxygen 55 L/min (HF55), High-Flow Nasal Oxygen 70 L/min (HF70)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Firat University