Clinical trials: Sedation During
Airway Obstruction
The Efficacy of Distal Pharyngeal Airway for Oxygenation During TEE
The purpose of this study is to investigate the effect of using the McMurray Enhanced Airway (MEA) which is a flexible extended-length distal pharyngeal airway on improving oxygen delivery compared to standard nasal cannula.
- Trial name
- NCT05974488
- Testing
- McMurray Enhanced Airway, Nasal Cannula
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Miami
Airway Obstruction, Apnea
Effectiveness of Continuous Negative External Pressure in Preventing Upper Airway Impairment During Routine Colonoscopy
The primary goal of this study is to determine the effectiveness and safety of delivering continuous negative external pressure (cNEP) to the upper airway as a means of preventing episodes of respiratory impairment (RI) such as…
- Conditions
- Airway Obstruction, Apnea, Hypopnea
- Trial name
- NCT01895062
- Testing
- Airway Management System (AMS)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- 5i Sciences, Inc.
Patients Undergoing Anesthesiologist-administered iv Sedation During Diagnostic/ Therapeutic Procedures
Evaluation of a New Airway Device - the YO2(R) Catheter in Patients Under Sedation
Patients under sedation not uncommonly develop upper airway obstruction or other respiratory complications and no airway device is available to provide reliable maintenance of the airway at present.
- Trial name
- NCT01709890
- Testing
- YO2(R) catheter
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Cerebral Palsy
Conscious Sedation With Nitrous Oxide in Control of Stress During Dental Care for Individuals With Cerebral Palsy
Cerebral Palsy induces oral alterations that impact on oral health, requiring dental treatment. The objective of this study was to evaluate the use of conscious sedation with nitrous oxide (N2O) in the control of stress during…
- Trial name
- NCT02322983
- Testing
- Control of Stress
- Where
- Brazil
- Volunteers
- 77 people
- Sponsor
- Universidade Cruzeiro do Sul
Diagnostic Gastroscopy
Intravenous Lidocaine to Reduce Propofol Consumption During Gastroscopy.
The goal of this clinical trial is to assess if intravenous administration of linisol reduce the propofol consumption and the sides effects of sedation during gastroscopy in healthy patients (ASA 1 and 2 patients).
- Trial name
- NCT05944887
- Testing
- Lidocaine 2% Injectable Solution, Propofol injection, gastroscopy
- Where
- Belgium
- Volunteers
- 46 people
- Sponsor
- Erasme University Hospital
Hypoxemia, Gastrointestinal Endoscopy
THRIVE in Sedated Gastrointestinal Endoscopy
This prospective observational study aims to evaluate the effectiveness of Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) compared to standard nasal cannula (SNC) oxygen supplementation in patients…
- Trial name
- NCT07487051
- Testing
- High-Flow Nasal Oxygen (THRIVE), Standard Nasal Cannula Oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 222 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Colonoscopy, Positive-Pressure Respiration
Comparison of High-flow Oxygen With or Without Nasal Positive Airway Pressure (PAP) During Propofol Sedation for Colonoscopy in an Ambulatory Surgical Center
The primary objective of the prospective study is to compare the incidence, duration, and severity of oxygen desaturation in high-risk patients randomized to nasal mask with nasal positive airway pressure (PAP) or standard care…
- Trial name
- NCT05754255
- Testing
- Nasal Cannula, Nasal Positive Airway Pressure System
- Where
- United States
- Sponsor
- Indiana University
COVID 19
Use of the Nasal Cannula During COVID-19
The objective of this investigation is to determine the incidence of the use of the low flow nasal cannula in suspected or confirmed cases with Covid-19
- Trial name
- NCT04376580
- Where
- Argentina
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tiva Group
Anesthesia
Hand Held Nitrous Oxide Delivery Device
To study the safety and efficacy of Hand Held Nitrous. A device that delivers 120 seconds of up to 72% nitrous oxide and ambient air.
- Trial name
- HHN (NCT02119403)
- Testing
- There are no other inteventions.
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Strata Medical Innovations
Lower Extremity Surgery
Fospropofol Disodium ED95 for Elderly Spinal Anesthesia Sedation
This study aims to determine the 95% effective dose (ED95) of fospropofol disodium, a new sedative drug, for adjuvant sedation during spinal anesthesia in elderly patients (aged 65 years and older) undergoing lower extremity…
- Trial name
- NCT07333508
- Testing
- Fospropofol Disodium
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Ya-Qun Zhou
Children Requiring Sedation for MRI/CT
The Incidence and Nature of Adverse Events During Pediatric Sedation for MRI/CT in One Korean University Hospital: Prospective Study
Sedation and anesthesia for which to perform diagnostic imaging represents a rapidly growing field of practice, especially in children. Propofol is the most common sedative drug administered for MRI/CT.
- Trial name
- NCT01855555
- Testing
- sedation with propofol
- Where
- South Korea
- Volunteers
- 2,948 people
- Sponsor
- Yonsei University
Bronchoscopy, Conscious Sedation
Sedation During Bronchoscopy:Dexmedetomidine vs Alfentanil
The purpose of this study is to find the best sedation necessary for patients undergoing bronchoscopy. Patients are randomized to three different regimes of sedation during bronchoscopy were studied: 1.
- Trial name
- NCT01805726
- Testing
- xylocain, Alfentanil, Dexmedetomidine
- Where
- Lebanon
- Volunteers
- 162 people
- Sponsor
- Saint-Joseph University
Anesthesia
Comparison of Depth of Sedation Performance Between SedLine and Comparator Device During General Anesthesia
The primary objective is to compare the performance of Masimo's SedLine and the comparator's device systems during surgery. Relative accuracy of the individual depth of sedation indices will be compared.
- Trial name
- NCT03865316
- Testing
- SedLine Vs Comparator Test Group
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Masimo Corporation
Anesthesia; Adverse Effect
A Single Dry EEG Electrode Allows to Estimate of the Level of Anesthesia During Colonoscopy Sedation.
We asked to a staff of digestive endoscopy and of the operating room to interpret the EEG traces obtained from a single dry electrode device to estimate the level of anesthesia during colonoscopy.
- Trial name
- NCT05584904
- Testing
- volunteer anesthesiologists and nurses
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Azienda USL Toscana Nord Ovest
Dental Caries, Child Behavior
Efficacy of Moderate Sedation for Dental Treatment of Young Children
There is lack of clinical trials on pediatric dental sedation. The purpose of this study is to test (using a randomized controlled trial design) the hypothesis that young children behavior during dental treatment improves with…
- Conditions
- Dental Caries, Child Behavior, Conscious Sedation Failure During Procedure
- Trial name
- NCT00902395
- Testing
- Midazolam, Protective stabilization, Midazolam, ketamine
- Where
- Brazil
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Hypoxemia
Capnography Monitoring During Intravenous Conscious Sedation Sedation With Midazolam for Oral Surgery
Dentists use sedation to help patients accept difficult procedures and to relieve anxiety. During sedation, the well-being of the patient is monitored by the dental team.
- Trial name
- NCT01949012
- Testing
- Capnography
- Where
- Ireland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University College Cork
Spinal Anesthesia
Effect of Atropine or Glycopyrrolate on the Prevention of Bradycardia During Sedation Using Dexmedetomidine in Geriatric Patients Undergoing Total Knee Replacement Under Spinal Anesthesia
Patients undergoing total knee arthroplasty with spinal anesthesia are often sedated to reduce patient discomfort due to large noises during surgery and also to reduce anxiety.
- Trial name
- NCT03322098
- Testing
- Atropine, Glycopyrrolate
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Yonsei University
Conscious Sedation Failure During Procedure
Oral Midazolam for Sedation in Esophagogastroduodenoscopy(EGD)
Can oral midazolam used for sedation in patients undergoing upper gastrointestinal endoscopy ?
- Trial name
- NCT01990937
- Testing
- Oral midazolam
- Where
- Thailand
- Volunteers
- 260 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Glaucoma
Comparing Conscious Sedation to Retrobulbar Block Anesthetics During Trans-scleral Diode Laser
This is a non-inferiority trial with a prospective randomized controlled design assessing patient satisfaction and complications associated with both retrobulbar block anesthetics (current gold standard) and conscious IV sedation…
- Trial name
- NCT03646500
- Testing
- Retrobulbar Block, Remifentanil
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Queen's University
Anxiety
Pre-procedural Anxiety and Sedation.
Colonoscopy is an outpatient procedure performed frequently as a screening test for diagnosis and treatment of a wide range of gastrointestinal problems.
- Trial name
- NCT01958151
- Testing
- State-Trait Anxiety Inventory Scores
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Basak Ceyda MECO