Clinical trials: Sedentary; Aging
Sedentary Lifestyle
Effectiveness of a Physical Exercise Prescription Program in Primary Care for Adults Aged 65 and Older: PREFIS-AP
This randomized controlled trial aims to evaluate the effectiveness of an individualized Physical Exercise Prescription Program delivered in Primary Care for adults aged 65 years and older.
- Trial name
- NCT07394790
- Testing
- Physical Exercise Prescription Program
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Biomédica de Salamanca
HIV
Pilot Study of the Effects of Exercise on Aging Among Older Persons With HIV
This pilot study will test the feasibility and acceptability of a 12 week combined aerobic and strength training intervention among persons with HIV who are age 50 or older and do not exercise frequently, and its preliminary…
- Trial name
- SEA (NCT01860261)
- Testing
- Aerobic and Strength Training Intervention
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of California, San Francisco
Physical Inactivity
Translational Control of Anabolic Resistance in Aging Muscle
This is an interventional study enrolling older individuals aged 60-85y to observe changes during physical inactivity. This study is investigating the relation between short-term physical inactivity and the impact of muscle…
- Trial name
- NCT03839628
- Testing
- Reduced Physical Activity
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obesity, Sarcopenic Obesity
The Physiologic Effects of Intranasal Oxytocin on Sarcopenic Obesity
Obesity is highly prevalent in older adults and is a major cause of sarcopenia and disability in older adults. Although exercise can counteract the effects of obesity and sarcopenia, many have difficulty adhering to an exercise…
- Conditions
- Obesity, Sarcopenic Obesity, Sarcopenia, Aging
- Trial name
- INOSO (NCT03119610)
- Testing
- Oxytocin nasal spray
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Sara Espinoza
Cognitive Aging
Elucidating How Physical Activity and Sleep Relate to Optimal Cognitive Ageing
Increased longevity is one of the greatest success stories in public health. However, ageing is accompanied by cognitive decline which affects people's daily functioning and, if it develops to dementia, their ability to live…
- Trial name
- PASOCA (NCT05455229)
- Where
- Belgium
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Aging, Mobility Limitation
Effects of Pilates Standing Exercises on Walking Mobility and Postural Balance
Importance: Aging is characterized by numerous molecular, physiological, functional, motor and psychological changes, such as loss of postural balance and reduced muscle mass/strength.
- Conditions
- Aging, Mobility Limitation, Postural Balance
- Trial name
- NCT03526757
- Testing
- Standing Pilates protocol, Standard Pilates protocol
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Sedentary Behavior, Aging
Promoting Fall Prevention Workshops
Physical Activity (PA) is recognized as the most effective method to prevent falls in the elderly. Yet despite there being a consensus now that Physical Activity (PA) is effective in practice, there remain many obstacles to…
- Trial name
- NCT04134585
- Testing
- semi-structured interviews
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Aging, Physical Function
Movement and Behaviours Measurement Study
There are few studies that already have validated specific raw accelerometer cut-points for people over 65 years old. The purpose of the present study is to validate raw accelerometer cut points for general people over 65 years…
- Conditions
- Aging, Physical Function, Frailty Syndrome, Physical Disability
- Trial name
- MOBEMENTS (NCT04173715)
- Testing
- Older Adults Group., Low Physical Function Status Group, Medium Physical Function Status Group
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Sedentary Older Adults, Sedentariness and Well-being
A-B-C Program for Sedentary Older Adults With Depressive Symptoms
The importance and benefits of leading a physically active lifestyle have been long studied. Examples of the multiple advantages from physical activity are improved health of the heart and brain, having a more independent living…
- Conditions
- Sedentary Older Adults, Sedentariness and Well-being, Sedentary; Aging
- Trial name
- A-B-C (NCT07176637)
- Testing
- A-B-C Program, Physical Activity Educational Program
- Volunteers
- 66 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Aging, Sedentary Behavior
Impact of Cocoa Flavanols on Pulmonary Oxygen Uptake Kinetics and Exercise Tolerance in Sedentary Middle-aged Adults
In recent years, there has been significant interest in dietary flavonoids (biologically active plant-derived compounds) as potential therapeutics.
- Trial name
- NCT04370353
- Testing
- Cocoa flavanols
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Sarcopenia, Physical Inactivity
Women in Action: A Multicomponent Intervention for Older Women
"Women in Action" is a quasi-experimental, mixed-methods study evaluating a 16-week multicomponent intervention (supervised strength/aerobic/balance training plus psychoeducational and nutrition-focused behavioral workshops) for…
- Conditions
- Sarcopenia, Physical Inactivity, Menopause, Healthy Aging
- Trial name
- WIA (NCT07860424)
- Testing
- Multicomponent exercise, nutrition, and psychoeducational program
- Where
- 2 sites in Spain
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Universidad de Oviedo
Aging, Mental Disorder
Self-Care for Dementia Caregivers
The Self-care for Dementia Caregivers Study is a behavioral health intervention that uses digital monitoring tools and motivational health coaching to help caregivers of persons with dementia engage in a regular routine of sleep…
- Conditions
- Aging, Mental Disorder, Eating, Healthy, Physical Inactivity
- Trial name
- Care2 (NCT05309577)
- Testing
- Behavioral Self-Monitoring + Motivational Interviewing
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Physical Inactivity, Aging
Home-Based Exercise Training in Older Adults During the COVID-19 Pandemic
The physical fitness and functionality of older adults are affected during the COVID-19 Pandemic. Regular exercise programs are effective in physical fitness and functioning in older adults.
- Conditions
- Physical Inactivity, Aging, COVID-19 Pandemic
- Trial name
- NCT05249764
- Testing
- Supervised Home Based Exercise Training, Unsupervised stretching and breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Baskent University
Appetite Loss, Physical Inactivity
APPETITE: Plant Protein and Exercise Solutions for the Prevention of Undernutrition in Older Adults.
The APPETITE Trial aims to investigate the efficacy of innovative plant protein fibre (PPF) products (developed in a previous workpackage) as part of a personalised diet with/out physical activity on appetite and incidence of…
- Conditions
- Appetite Loss, Physical Inactivity, Undernutrition, Anorexia of Aging
- Trial name
- NCT05608707
- Testing
- Physical activity intervention, Personalised nutrition intervention
- Where
- 3 sites in Germany, Ireland and 1 more
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Physical Inactivity, Aging
Robot-based Intervention to Improve Physical Activity in Older Adults
Physical inactivity is considered a global pandemic negatively impacting the health of over 60% of older adults in America. Interventions aimed at improving physical activity in older adults focus on training reflective processes…
- Conditions
- Physical Inactivity, Aging, Sedentary Behaviors, Bias, Implicit
- Trial name
- NCT06843161
- Testing
- The jog or ground go no go task for retraining automatic bias
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Ottawa
Stroke, Insulin Resistance
Trial of Aerobic Exercise Training in Stroke Survivors
The purpose of this study is to examine the effects of treadmill training on inflammation in the skeletal muscle and adipose tissue, insulin action in the skeletal muscle, and whole body glucose metabolism in stroke survivors.
- Conditions
- Stroke, Insulin Resistance, Sedentary Lifestyle
- Trial name
- NCT00891514
- Testing
- Aerobic Exercise, Stretching
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Baltimore VA Medical Center
Physical Activity, Aging
Long Distance Running Training by Older Adults
The goal of this project is to understand the effect of regular practice of long distance running on the posture and movement control of older adults.
- Trial name
- NCT01475448
- Testing
- Long distance training, Walking training
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Aging, Sedentary Lifestyle
Nitrites, Skeletal Muscle Mitochondrial Bioenergetics, and Physical Activity in Old Age
This 2-site randomized double blinded controlled trial is to confirm and more definitively clarify the impact of a 12-week course of nitrite versus placebo on mitochondrial bioenergetics in older sedentary adults.
- Conditions
- Aging, Sedentary Lifestyle, Frailty
- Trial name
- Nitrite (NCT04405180)
- Testing
- 20mg sodium nitrite tid
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Gladwin, Mark, MD
Sedentary Lifestyle
Exercise Effects on Brain Health and Learning From Minutes to Months
Given the accelerating growth of older adults worldwide and the decline in cognitive function with aging, therapeutics that remediate age-related cognitive decline are needed more than ever.
- Trial name
- EXTEND (NCT03114150)
- Testing
- Cardiorespiratory fitness training, Functional fitness training
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Michelle W. Voss
Physical Inactivity, Healthy
Supervised Center-based vs. Unsupervised Home-based Exercise Programs (PRO-Training)
The superiority of supervised center-based training programs compared with unsupervised home-based ones in older adults remains unclear, and no evidence exists on whether including a motivational component could moderate these…
- Conditions
- Physical Inactivity, Healthy, Older Adult
- Trial name
- PRO-Training (NCT05619250)
- Testing
- Unsupervised home-based exercise group without motivational intervention (UNSUP), Unsupervised home-based exercise group with motivational intervention (UNSUP+), Supervised center-based exercise group without motivational intervention (SUP)
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha