Clinical trials: Segment Elevation Myocardial Infarction (STEMI)
Myocardial Infarction, Acute Coronary Syndrome
HeartHome: A Nurse-Driven, Home-Based Cardiac Rehabilitation Program
The purpose of this implementation trial is to execute a nurse-led, home-based cardiac rehabilitation (HBCR) program, evaluate the program's impact on patient outcomes over 6 months; and compare outcomes of HeartHome (HH)…
- Conditions
- Myocardial Infarction, Acute Coronary Syndrome, ST-segment Elevation Myocardial Infarction (STEMI), Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)
- Trial name
- NCT04131816
- Testing
- HeartHome
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of North Carolina, Chapel Hill
Acute Coronary Syndrome, Non-ST Elevation (NSTEMI) Myocardial Infarction
An Efficacy and Outcome Study of Supplemental Oxygen Treatment in Patients With Suspected Myocardial Infarction
The use of supplemental oxygen in the setting of suspected acute myocardial infarction (AMI) is manifested in international treatment guidelines and established in prehospital and hospital clinical routine throughout the world.
- Conditions
- Acute Coronary Syndrome, Non-ST Elevation (NSTEMI) Myocardial Infarction, Acute ST Segment Elevation Myocardial Infarction, Angina, Unstable
- Trial name
- DETO2X-AMI (NCT01787110)
- Testing
- Oxygen
- Where
- 34 sites in Sweden
- Volunteers
- 6,629 people
- Sponsor
- Karolinska Institutet
Myocardial Infarction
A Clinical Evaluation of Everolimus Eluting Coronary Stents in the Treatment of Patients With ST-segment Elevation Myocardial Infarction: EXAMINATION Study
This study is a prospective, randomized controlled, single blind, two-arm, multi center clinical evaluation. A total of 1500 patients will be enrolled in the study.
- Trial name
- NCT00828087
- Testing
- Everolimus Eluting Coronary Stent System, cobalt chromium balloon expandable stent ( non drug eluting stent Arm)
- Where
- 11 sites in Italy, Netherlands and 1 more
- Volunteers
- 1,504 people
- Sponsor
- Spanish Society of Cardiology
ST Elevation Myocardial Infarction, Arrhythmia Ventricular
Different Reperfusion Timing and Ventricular Arrhythmias in STEMI Patients
The aim of this study was to investigate the association between different reperfusion timing and ventricular arrhythmias (VAs) to provide evidence for clinical decision-making for patients with ST-segment elevation myocardial…
- Trial name
- NCT04660474
- Where
- China
- Volunteers
- 517 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Heart Failure and ST Elevation Myocardial Infarction
Predictors of Heart Failure After ST-segment Elevation Myocardial Infarction (HF-EXPRESS)
Objective: The purpose of this project is to study the post miyocardial infaction (MI) damage and subsequently developed post-infarct cardiac repair process on the basis of cellular, molecular and imaging techniques.
- Trial name
- HF-EXPRESS (NCT02650934)
- Testing
- Percutanous coronary intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 312 people
- Sponsor
- Dr. Nafiz Korez Sincan State Hospital
Angina Pectoris, Unstable Angina
Pilot Study of Hemoglobin Based Oxygen Therapeutics in Elective Coronary Revascularization
The purpose of this study is to assess the safety and feasibility of a novel oxygen carrying solution, HBOC-201, in the setting of PCI for Acute Coronary Syndromes from randomization til hospital discharge.
- Conditions
- Angina Pectoris, Unstable Angina, Myocardial Infarction
- Trial name
- NCT00317512
- Testing
- Percutaneous Coronary Revascularization, Hemoglobin-Based Oxygen Carrier-201 (HBOC-201), Voluven
- Where
- 6 sites in Belgium, Germany and 1 more
- Volunteers
- 45 people
- Sponsor
- Biopure Corporation
STEMI, Multi Vessel Coronary Artery Disease
STaged Interventional Strategies for Acute ST-seGment Elevation Myocardial Infarction Patient With Multi-vessel Disease（STAGED）
An investigator-initiated, randomized, multicenter, two-arm, open-label study of consecutive patients presenting with STEMI and MVD Objectives: The present study aimed to investigate the difference in major adverse cardiac event…
- Conditions
- STEMI, Multi Vessel Coronary Artery Disease, Percutaneous Coronary Intervention, AMI Patients With Multivessel Disease, Staged PCI
- Trial name
- SAGED (NCT04918030)
- Testing
- Early staged PCI, Late staged PCI
- Where
- China
- Volunteers
- 1,586 people
- Sponsor
- Xiamen Cardiovascular Hospital, Xiamen University
Stable Angina, Unstable Angina
Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial
We had little experience in coronary intervention with recently introduced newer drug-eluting stent (DES) platforms, despite great anticipation, and optimal duration of dual antiplatelet therapy (DAPT) for these stent systems…
- Conditions
- Stable Angina, Unstable Angina, Non-ST Segment Elevation Myocardial Infarction
- Trial name
- HOST-IDEA (NCT02601157)
- Testing
- 3-months DAPT, 1-year DAPT
- Where
- 12 sites in South Korea
- Volunteers
- 2,173 people
- Sponsor
- Seoul National University Hospital
STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation MI
HELicobacter Pylori Screening in Patients With Acute Myocardial Infarction Pilot Study
The aim of this study is to determine the prevalence of Helicobacter pylori (Hp) infection in patients with myocardial infarction (MI).
- Trial name
- HELPpilot (NCT04289012)
- Testing
- Helicobacter Pylori screening by UBT
- Where
- 2 sites in Sweden
- Volunteers
- 300 people
- Sponsor
- Karolinska Institutet
Myocardial Infarction, Acute, ST Segment Elevation Myocardial Infarction
A Trial on the Role of Community Pharmacist in Improving Adherence and Clinical Outcomes in Post-Infarction
The purpose of this pilot study is to evaluate the effectiveness of the active involvement of Community Pharmacists in improving adherence to medical prescriptions in patients with acute myocardial infarction (AMI), reducing the…
- Conditions
- Myocardial Infarction, Acute, ST Segment Elevation Myocardial Infarction, Non-ST Elevation Myocardial Infarction (nSTEMI)
- Trial name
- IM-ADHERENCE (NCT03621111)
- Testing
- Patient-counseling, Patient self-administered questionnaire, Pills counts
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda ULSS 5 Polesana
Ischemic Heart Disease (IHD)
XTR003 PET Radiotracer for the Detection of Viable Myocardium
The study was designed to explore the clinical feasibility of XTR003, a PET myocardial fatty-acid tracer, for the detection of viable myocardium in patients with ischemic heart disease (IHD).
- Trial name
- NCT05885854
- Testing
- XTR003
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Sinotau Pharmaceutical Group
ST Elevation Myocardial Infarction
Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With STEMI
The objective is to compare a reduced stent strategy based on drug-coated balloon (DCB) percutaneous coronary intervention (PCI) with conventional drug-eluting stent (DES) coronary revascularization in patients presenting with…
- Trial name
- COPERNICAN (NCT06353594)
- Testing
- Primary PCI
- Where
- 23 sites in Spain
- Volunteers
- 1,272 people
- Sponsor
- Hospital Universitario La Fe
ST-Segment Elevation Myocardial Infarction
Ezetimibe In Addition To Atorvastatin Therapy On The Plaque Composition In Patients With Acute Myocardial Infarction.
The purpose of the study is to examine the effect of the cholesterol lowering agent Ezetimibe when used in addition to optimal treatment with Atorvastatin in patients with acute ST-Elevation Myocardial Infarction (STEMI) who have…
- Trial name
- OCTIVUS (NCT01385631)
- Testing
- Ezetimibe
- Where
- Denmark
- Volunteers
- 87 people
- Sponsor
- Odense University Hospital
ST Segment Elevation Myocardial Infarction, Left Ventricular Thrombus
Prevention of Post-STEMI Left Ventricular Thrombus With Optimized Anticoagulant (EARLYmyo-LVT Ⅱ)
Left ventricular thrombus is a common complication subsequent to ST-segment elevation myocardial infarction (STEMI) that related to increased embolic events.
- Trial name
- NCT03786757
- Testing
- Rivaroxaban
- Where
- China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
STEMI, Diabetes Mellitus
Analysis of the Microbiota and STEMI
Hyperglycemia is a common finding in patients diagnosed with acute coronary syndrome (ACS), and an independent predictor of mortality in patients with and without diabetes.
- Conditions
- STEMI, Diabetes Mellitus, Microbial Colonization
- Trial name
- NCT03439592
- Testing
- collection of fecal material
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Campania Luigi Vanvitelli
STEMI, Large Thrombus Burden
Upfront Premedication For Reduction of Microvascular Obstruction and No-reflow in Treating ST-segment Elevation Myocardial Infarction
Angiographic no-reflow during primary PCI procedures occurs at relatively high rate (25%) and is associated with worsening of long term morbidity and mortality.
- Conditions
- STEMI, Large Thrombus Burden, No-Reflow Phenomenon
- Trial name
- UPFRONT-STEMI (NCT05393557)
- Testing
- Upfront preparation of microcirculation to minimize risks of no-reflow and reperfusion injury
- Volunteers
- 626 people
- Sponsor
- Cairo University
ST Elevation Myocardial Infarction, Non-ST Elevation Myocardial Infarction
IVUS Versus FFR for Non-infarct Related Artery Lesions in Patients With Multivessel Disease and Acute MI
The aim of the study is to compare clinical outcomes between intravascular ultrasound (IVUS)-guided treatment decision versus fractional flow reserve (FFR)-guided treatment decision for non-infarct related artery stenosis in…
- Trial name
- FRAME-AMI2 (NCT05812963)
- Testing
- IVUS-guided PCI group, FFR-guided PCI group
- Where
- 2 sites in South Korea
- Volunteers
- 1,400 people
- Sponsor
- Samsung Medical Center
Acute Myocardial Infarction
Minimizing Reperfusion Injury in Patients With Acute Myocardial Infarction
The size of a heart attack will be decreased by the use of timed balloon inflations to open the blocked blood vessel.
- Trial name
- PCinAMI (NCT00846378)
- Testing
- Post conditioning, Usual Care for STEMI
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
ST-segment Elevation Myocardial Infarction (STEMI)
Fast Radial Pharmaco-invasive Strategy In ST Elevation Myocardial Infarction Trial
INTRODUCTION: The pharmaco-invasive strategy is a safe alternative to primary percutaneous coronary intervention (PCI) in patients with ST elevation acute myocardial infarction, who cannot be in the cathlab in less than 120…
- Trial name
- FARADMI (NCT04300582)
- Testing
- Cardiac catheterization standard strategy, Cardiac catheterization fast strategy
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo General Hospital
ST Segment Elevation Myocardial Infarction
DANish Study of Optimal Acute Treatment of Patients With ST-elevation Myocardial Infarction
This study focuses on Cardioprotective strategies.
- Trial name
- DANAMI-3 (NCT01435408)
- Testing
- Conventional primary PCI, Ischemic postconditioning., Deferred stenting in primary PCI.
- Where
- 5 sites in Denmark
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet