Clinical trials: Segment Elevation Myocardial Infarction (STEMI)
ST Segment Elevation Myocardial Infarction
Italian Multi-center Registry of Self-apposing Coronary Stent in Patients With STEMI
The aim of this registry is to collect clinical data on nitinol self-expanding STENTYS Xposition S™ in order to evaluate the efficacy and safety in patients presenting with ST segment elevation myocardial infarction
- Trial name
- iPOSITION (NCT02979236)
- Testing
- STENTYS Xposition S
- Where
- 8 sites in Italy
- Volunteers
- 250 people
- Sponsor
- UOSD Emodinamica Diagnostica e Interventistica
Stable Angina, Non ST Segment Elevation Myocardial Infarction
INsTantenous wavE-Free Ratio-guided PCI Versus Fractional Flow REserve-Guided PCI in rouTine Clinical Practice, Prospective, Multicenter Registry
The current study sought to evaluate the clinical relevance of iFR-guided strategy in real world clinical practice using unrestricted study population from stable angina to acute coronary syndrome including acute ST-segment…
- Conditions
- Stable Angina, Non ST Segment Elevation Myocardial Infarction, ST-segment Elevation Myocardial Infarction, Silent Myocardial Ischemia
- Trial name
- INTERPRET (NCT03338309)
- Testing
- Instantaneous wave-free ratio measurement
- Where
- 4 sites in South Korea
- Volunteers
- 1,200 people
- Sponsor
- Samsung Medical Center
ST Elevation Myocardial Infarction
Relationship Between Left Ventricular Remodeling, Coronary Endothelial Function and Myocardial Fibrosis Using Positron Emission Tomography in Patients With ST-elevation Myocardial Infarction
Left ventricular remodeling is a common complication in patients with ST-elevation myocardial infarction (STEMI ) and may lead to heart failure.
- Trial name
- REMOD-TEP (NCT02789098)
- Testing
- (15)-O water positron emission tomography and Biomarkers
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
ACS - Acute Coronary Syndrome, NSTEMI - Non-ST Segment Elevation MI
MCG Discovery Study in Emergency Departments
This prospective discovery study is designed to demonstrate the feasibility of using an unshielded, mobile MCG device in an Emergency Department (ED) setting.
- Trial name
- NCT06095557
- Testing
- Sponsor MCG device
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- SB Technology, Inc.
STEMI
Randomized Placebo-controlled Trial of Inhaled iNO in Acute ST-segment Elevation MI Treated by Primary Angioplasty
Reperfusion of ischemic myocardium, termed ischemia/reperfusion during the treatment of MI may result in paradoxical myocardial injury compromising myocardial salvage and left ventricular functional recovery.
- Trial name
- ENAMOR (NCT00854711)
- Testing
- inhaled nitric oxide
- Where
- Israel
- Volunteers
- 7 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Acute ST Segment Elevation Myocardial Infarction, Prognosis
Predictive Value of Combining AccuIMR and AccuFFR in Patients With STEMI
Patients with acute myocardial infarction were enrolled retrospectively. The fractional flow reserve (AccuFFR) and microcirculatory resistance index (AccuIMR) based on coronary angiography were analyzed, and the relationship…
- Trial name
- NCT06435728
- Testing
- AccuIMR and AccuFFR
- Where
- China
- Volunteers
- 1,297 people
- Sponsor
- Peking University Third Hospital
Myocardial Infarction
Reperfusion Time in ST Segment Elevation Myocardial Infarction (STEMI)
Reperfusion delay in STEMI has been shown to be excessive in our community. In order to improve delay a fast track (direct transfer in catheterization laboratory) has been implemented.
- Trial name
- NCT00497419
- Testing
- fast track
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University Hospital, Geneva
ST-segment Elevation Myocardial Infarction
Optimal Coronary Flow After PCI for Myocardial Infarction - a Pilot Study
In this study the investigators test the hypothesis that alteplase given intra coronary after PCI reduce infarct size in patients with ST-elevation myocardial infarction(STEMI) and impaired microvascular function defined as a…
- Trial name
- OPTIMAL (NCT02894138)
- Testing
- alteplase
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Vastra Gotaland Region
Atrial Fibrillation
The Incidence and Predictors of Developing Atrial Fibrillation in Patients With Inferior ST-segment Elevation Myocardial Infarction After Primary Percutaneous Coronary Intervention
Is to analyze the incidence and predictors of developing AF in patients with inferior infarction who undergo PCI with and without atrial and SN branches occlusion
- Trial name
- NCT03854448
- Testing
- holter monitoring
- Volunteers
- 109 people
- Sponsor
- Assiut University
Reperfusion Injury, Myocardial
Effects of Melatonin on Reperfusion Injury
Acute myocardial infarction is a major cause of mortality and morbidity. Primary percutaneous coronary intervention (pPCI) is currently the most effective treatment strategy in acute myocardial infarction.
- Trial name
- NCT03303378
- Testing
- melatonin (Helsinn Chemical Co, Biasca, Switzerland)
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Chinese PLA General Hospital
Acute ST-segment Elevation Myocardial Infarction
EARLY Routine Catheterization After Alteplase Fibrinolysis vs. PPCI in ST-Segment-Elevation MYOcardial Infarction
The EARLY-MYO (EARLY routine catheterization after alteplase fibrinolysis vs. primary PCI in acute ST-segment elevation MYOcardial infarction) is an investigator-initiated, prospective, multicenter, randomized (1:1), open-label…
- Trial name
- EARLY-MYO (NCT01930682)
- Testing
- Alteplase, Early post-fibrinolytic catheterisation, Primary PCI
- Where
- China
- Volunteers
- 344 people
- Sponsor
- RenJi Hospital
Distal Radial Artery Approach, ST Elevation Myocardial Infarction
Comparison of Success Rate Between Distal Radial Approach and Radial Approach in STEMI
ST-segment elevation myocardial infarction (STEMI) is an emergent disease to treat as soon as possible. 2017 ESC guidelines for the management of STEMI recommend using radial approach (RA) rather than femoral approach (FA) to…
- Trial name
- NCT03611725
- Testing
- Distal radial artery, Radial artery
- Where
- 3 sites in South Korea
- Volunteers
- 352 people
- Sponsor
- Wonju Severance Christian Hospital
ST Segment Elevation Myocardial Infarction (STEMI), Coenzyme Q10
Effect Supplementation of COenzyme Q10 in Acute STEMI Underwent PPCI
Left ventricular remodeling can still occur after primary percutaneous coronary intervention (PCI). Global longitudinal strain (GLS) assessment has been used as a predictor of left ventricular remodeling.
- Trial name
- ESCOMI (NCT06661018)
- Testing
- Coenzyme Q 10
- Where
- 2 sites in Indonesia
- Volunteers
- 46 people
- Sponsor
- Universitas Diponegoro
ST-elevation Myocardial Infarction (STEMI)
Drug-Coated Balloon Versus Drug-Eluting Stent in Patient With ST-Segment Elevation Myocardial Infarction
Acute ST-segment elevation myocardial infarction (STEMI) is a life-threatening emergency requiring immediate intervention. The incidence of premature coronary artery disease (PCAD) is rising rapidly in China; its long-term…
- Trial name
- DCB-STEMI (NCT06742125)
- Testing
- Drug-coated balloon (DCB), Drug-eluting stent (DES)
- Where
- China
- Volunteers
- 1,244 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
ST-segment Elevation Myocardial Infarction
Manual Thrombus Aspiration During PCI in STEMI With Angiographically Evident Thrombus
The goal of this clinical trial is to determine whether manually removing a visible blood clot before percutaneous coronary intervention (PCI) improves outcomes in patients with ST-segment elevation myocardial infarction (STEMI).
- Trial name
- TAPSET (NCT06654453)
- Testing
- Manual thrombus aspiration, Percutaneous Coronary Intervention
- Where
- China
- Volunteers
- 3,500 people
- Sponsor
- Shenghua Zhou
ST Segment Elevation Myocardial Infarction
Microvascular Dysfunction in Acute Myocardial Infarction (AMI) and Its Relation to Outcome
The purpose of this study is first to evaluate absolute myocardial blood flow and resistance over time in the acute and sub-acute phase of myocardial infarction and second, to correlate these parameters to preservation of left…
- Trial name
- NCT01538303
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
ST-segment Elevation Myocardial Infarction
Henan STEMI Registry
ST-segment elevation myocardial infarction (STEMI) remains among the most acute and critical diseases, with primary percutaneous coronary intervention (pPCI) and thrombolysis as mainstay reperfusion treatments.
- Trial name
- NCT02641262
- Where
- China
- Volunteers
- 5,479 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Out of Hospital Cardiac Arrest Without ST-segment Elevation
Performance of Coronary CT Angiography to Rule Out Coronary Artery Disease After Out-of-hospital Cardiac Arrest
Out-of-hospital cardiac arrest (OHCA) has multiple etiologies. In the absence of ST-elevation myocardial infarction, percutaneous coronary intervention (PCI) is delayed.
- Trial name
- PERFECCT (NCT05961488)
- Testing
- Coronary Calcium Score and Coronary CT angiogram
- Where
- France
- Volunteers
- 200 people
- Sponsor
- CHU de Reims
ST-elevation Myocardial Infarction (STEMI)
The Impact of Post Stenting Balloon Dilatation on Coronary Microcirculation in STEMI Patients Undergoing PPCI
This study aims to assess the impact of NC balloon post-dilatation on coronary microcirculation in patients with ST segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI).
- Trial name
- POSTDILSTEMI (NCT02788396)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Mid and South Essex NHS Foundation Trust