Clinical trials: Segmentation
Acute Chest Pain, NSTEMI - Non-ST Segment Elevation MI
Emergency Department Triage of Patients With Acute Chest Pain Based on the ESC 0/1-hour Algorithm (PRESC1SE-MI)
The PRESC1SE-MI study compares two algorithms for triage of patients presenting with chest pain and symptoms of heart attack (myocardial infarction) to the emergency department.
- Trial name
- PRESC1SE-MI (NCT05649384)
- Testing
- European Society of Cardiology hs-cTnT/I 0 h/1 h algorithm, European Society of Cardiology hs-cTnT/I 0 h/3 h algorithm
- Where
- 20 sites in United States, Australia and 9 more
- Volunteers
- 64,374 people
- Sponsor
- University Hospital, Basel, Switzerland
Punctal Stenosis
AS OCT Evaluation for Perforated Punctual Plugs
Evaluation of the perforated punctal plugs after implantation in cases of punctal stenosis regarding position and patency in the early postoperative period (during the first operative weak)
- Trial name
- NCT04624022
- Testing
- Anterior segment optical coherent tomography
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Minia University
Health Status
Simple Segmentation Tool to Understand Elderly Health Status and Needs
Background: The delivery of targeted, patient-centered care for a population with heterogeneous healthcare needs while moderating costs is a key challenge in healthcare.
- Trial name
- NCT02663037
- Where
- Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Early Management, Acute Heart Failure
Early Management Strategies of Acute Heart Failure for Patients With NSTEMI
There are always poor outcomes in patients with acute myocardial infarction(AMI) combined with elevated BNP/NT-proBNP level. An elevated BNP/NT-proBNP level highly indicates acute heart failure(AHF).Levosimendan is recommended in…
- Conditions
- Early Management, Acute Heart Failure, NSTEMI - Non-ST Segment Elevation MI
- Trial name
- EMSAHF (NCT03189901)
- Testing
- Regular management+Levosimendan
- Where
- 14 sites in China
- Volunteers
- 470 people
- Sponsor
- Qilu Hospital of Shandong University
Keratoconus
Combined Corneal Wavefront-guided TPRK and ACXL Following ICRS Implantation in Management of Moderate Keratoconus
Background: Keratoconus leads to gradual progressive loss of vision in young and adult patients. For visual rehabilitation and to hinder keratoconus progressionthe investigators designed this study to help the keratoconus…
- Trial name
- NCT04383301
- Testing
- Intracorneal ring segment implantaion as the first stage, ACXL and wafe front guieded TPRK as the second stage
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- Shaaban Elwan
Acute Coronary Syndrome, Non ST Segment Elevation Acute Coronary Syndrome
Early Initiation of Tafolecimab for Patients With Acute Coronary Syndromeundergoing Percutaneous Coronary Intervention in Chinese Population
For patients with ACS undergoing PCI, intensive lipid-lowering including PCSK9 monoclonal antibody should be started as soon as possible, that is, lower LDL-C level should be achieved as soon as possible.
- Conditions
- Acute Coronary Syndrome, Non ST Segment Elevation Acute Coronary Syndrome, Lipid Lowering, Vascular Inflammation
- Trial name
- NCT06096909
- Testing
- Tafolecimab, Cholesterol Absorption Inhibitor, Statin
- Where
- 2 sites in China
- Volunteers
- 3,684 people
- Sponsor
- China National Center for Cardiovascular Diseases
Urinary Stone, Renal Colic
Radiomics and Image Segmentation of Urinary Stones by Artificial Intelligence
Kidney stone disease causes significant morbidity, and stones obstructing the ureter can have serious consequences. Imaging diagnostics with computed tomography (CT) are crucial for diagnosis, treatment selection, and follow-up.
- Conditions
- Urinary Stone, Renal Colic, Obstruction Ureter, Urosepsis
- Trial name
- RISUS_AI (NCT06412900)
- Where
- Norway
- Volunteers
- 522 people
- Sponsor
- Oslo University Hospital
Unstable Angina, Myocardial Infarction
SYNERGY: Open Study of Enoxaparin Versus Unfractionated Heparin in Patients With Acute Coronary Syndromes
Patients experiencing a mild heart attack will receive one of two medications which thin the blood to discern which is superior.
- Conditions
- Unstable Angina, Myocardial Infarction, Myocardial Ischemia
- Trial name
- NCT00043784
- Testing
- enoxaparin
- Where
- United States
- Volunteers
- 8,000 people
- Sponsor
- Sanofi
ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention
Clinical Efficacy and sAfety of Intravenous Infusion of Nicorandil During Primary Percutaneous Coronary Intervention
The investigators evaluate the efficacy and safety of intravenous administration of nicorandil as adjuncts to reperfusion treatment in acute ST-segment elevation acute myocardial infarction (STEMI) patients undergoing primary…
- Trial name
- CLEAN (NCT04665648)
- Testing
- Nicorandil
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Fudan University
Non-ST-segment Elevation Myocardial Infarction
Study on High-sensitivity Troponin 0h/1h for Rapid Diagnosis of Non-ST-segment Elevation Myocardial Infarction in the Chinese Population
The purpose of the study is to establish a high-sensitivity troponin 0h/1h process for the diagnosis of patients suspected of NSTEMI for the Chinese population, obtain the inclusion and exclusion criteria for diagnosis of these…
- Trial name
- NCT03331549
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Beijing Anzhen Hospital
ST-segment Elevation Myocardial Infarction
EROSION II: OCT Guided PPCI in STEMI
This protocol describes a prospective, multi-center study intended to test the hypothesis that patients with STEMI caused by plaque rupture or plaque erosion without obstructive stenosis (diameter stenosis <70%) can be stabilized…
- Trial name
- NCT03062826
- Testing
- dual antiplatelet therapy (aspirin + ticagrelor or aspirin + clopidogrel)
- Where
- 16 sites in China
- Volunteers
- 347 people
- Sponsor
- Harbin Medical University
Acute Coronary Syndrome
Invasive vs Conservative Strategies in Non-ST-elevation Acute Coronary Syndrome and Comorbidities
The guidelines of clinical practice, based on the randomized studies, recommend an invasive strategy in non-ST elevation acute coronary syndrome (NSTEACS).
- Trial name
- MOSCA (NCT01645943)
- Testing
- Coronary angiogram
- Where
- 6 sites in Spain
- Volunteers
- 109 people
- Sponsor
- University of Valencia
Diabetic Macular Edema
Anterior and Posterior Segment Vascular Changes Following Laser and Anti-Vascular Endothelial Growth Factor (VEGF) Treatment of Diabetic Retinopathy
The study will investigate changes in the structure and function of blood vessels in the front and back of the eye following laser and anti-VEGF treatments for sight-threatening diabetic eye disease.
- Trial name
- VEGF (NCT01196325)
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Irreversible Pulpitis (Toothache)
Evaluation Of Laser Versus Conventional Pulpotomies In Mature Molar Teeth With Irreversible Pulpitis
this clinical trial is evaluating the outcome of laser assisted pulpotomy compared to conventional pulpotomy in mature teeth with symptomatic irreversible pulpitis (SIP) assessed by CBCT followed by automated segmentation using…
- Trial name
- NCT07287709
- Testing
- Diode laser, Sodium Hypochlorite Solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Rana Hegaz
Pregnancy, Obstetric Labor
Fetal ST Segment and T Wave Analysis in Labor
The purpose of this research is to test a new instrument, called a fetal STAN monitor, that may be used during labor to monitor the electrical activity of the baby's heart.
- Conditions
- Pregnancy, Obstetric Labor, Parturition
- Trial name
- STAN (NCT01131260)
- Testing
- fetal STAN monitor
- Where
- 13 sites in United States
- Volunteers
- 11,108 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Cataract
A Cataract Surgery Clinical Trial
The purpose of the study is to compare the efficiency and safety of UNITY™ Vitreoretinal Cataract System (UNITY VCS) to CENTURION® Vision System with Active Sentry (CAS) in adult subjects with grade 2 or greater nuclear sclerotic…
- Trial name
- NCT07044674
- Testing
- UNITY Vitreoretinal Cataract System, CENTURION Vision System with Active Sentry, Anterior segment ophthalmic surgery
- Where
- 5 sites in United States
- Sponsor
- Alcon Research
Eye Diseases
Manual Versus Automated Choroidal Thickness Measurements Using Swept-source Anterior Segment OCT
The choroid, which is located between the retina and the sclera, is a connective tissue layer that is densely packed with blood vessels and is responsible for supplying oxygen and nutrients to the retina's periphery.
- Trial name
- NCT05211089
- Testing
- Optical Coherence Tomography imaging of choroid
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Stable Angina, Unstable Angina
Efficacy of Vitamin E in Preventing Contrast-Induced Acute Kidney Injury Following Coronary Angiography
The purpose of this study is to evaluate the effect of vitamin E on preventing from incidence of contrast induced acute kidney injury (CI-AKI) in the patients who undergone coronary angiography.
- Conditions
- Stable Angina, Unstable Angina, Non ST Segment Elevation Myocardial Infarction, Post MI
- Trial name
- NCT02070679
- Testing
- Vitamin E
- Where
- 2 sites in Iran
- Volunteers
- 284 people
- Sponsor
- Urmia University of Medical Sciences
ST Segment Elevation Myocardial Infarction
DANish Study of Optimal Acute Treatment of Patients With ST-elevation Myocardial Infarction
This study focuses on Cardioprotective strategies.
- Trial name
- DANAMI-3 (NCT01435408)
- Testing
- Conventional primary PCI, Ischemic postconditioning., Deferred stenting in primary PCI.
- Where
- 5 sites in Denmark
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Coronary Syndrome, Type 2 Diabetes
Evaluation of Continuous Glucose Monitoring in Patients With ACS and Type 2 Diabetes in ICU
The investigators hypothesize that the use of a continuous glucose monitoring system (CGMS) can reduce glycemic variability assessed by coefficient of variation (CV) during the acute phase of acute coronary syndrome (ACS) in…
- Trial name
- EVASION (NCT04822740)
- Testing
- Control Glucose Monitoring System
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris