Clinical trials: Segmentation, active
STEMI - ST Elevation Myocardial Infarction
Century Clot-Guided Prophylactic Rivaroxaban for Post STEMI Complicating Left Ventricular Thrombus
To manage the ST-segment elevation myocardial infarction (STEMI) caused by plaque rupture, triggers platelet activation/aggregation and thrombin generation, requires dual (platelet and coagulation) pathway inhibition.
- Trial name
- NCT06013020
- Testing
- NOAC+DAPT, DAPT
- Where
- China
- Volunteers
- 374 people
- Sponsor
- Zunyi Medical College
STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation MI
Evolocumab or Normal Strategies to Reach LDL Objectives in Acute Myocardial Infarction Upbound to PCI
AMUNDSEN-real is a phase IV, international (7 European countries), multicenter, controlled, open label study randomized, in 2 parallel groups of patients with a diagnosis of STEMI or NSTEMI with an indication for PCI, using the…
- Trial name
- AMUNDSEN (NCT04951856)
- Testing
- Evolocumab 140 MG/ML, Standard of care (SOC)
- Where
- France
- Volunteers
- 2,166 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myopia Progression
Management of Myopia in University Students With DIMS-TED Spectacle Lenses
The purpose of the study is to quantify the effectiveness of Hoya MiyoSmart IQ (DIMS-TED) spectacle lenses in slowing the rate of myopia progression in university students.
- Trial name
- MoMUS-DIMS (NCT07679477)
- Testing
- DIMS TED spectacle lenses, Single vision spectacle lenses
- Where
- 2 sites in United Kingdom
- Volunteers
- 38 people
- Sponsor
- University of Bradford
STEMI, PCI
Intravascular Ultrasound guidaNce versuS angIoGrapHy Guidance in Patients With ST-segment Elevation Myocardial Infarction
STEMI represents the subtype of ACS with the worst prognosis, associated with high mortality and an elevated risk of complications. The use of IVI guidance holds the potential to reduce the incidence of MACE.
- Trial name
- INSIGHT-STEMI (NCT07616024)
- Testing
- Intravascular Ultrasound, Coronary angiography guidance
- Where
- China
- Volunteers
- 2,488 people
- Sponsor
- Shanghai Zhongshan Hospital
Adjacent Segment Degeneration
Extended One-level Interbody Fusion for Adjacent Vacuum Phenomenon in Lumbar Degenerative Disc Disease
The main objective of this study was to validate the clinical effectiveness of interbody fusion with a one-segment extension for the treatment of adjacent segmental space discs in the surgical treatment of lumbar degeneration.
- Trial name
- NCT06029764
- Testing
- extended one-level interbody fusion
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Xuanwu Hospital, Beijing
Posterior Chamber Phakic Intraocular Lens, Vault
Study on the Diagnostic Efficacy of ICL Selection and Prediction Depth Model Based on Eye Images
To evaluate the diagnostic efficacy of deep learning network model in implantable collamer lens selection and prediction in a multicenter cross-sectional study
- Conditions
- Posterior Chamber Phakic Intraocular Lens, Vault, Deep Neural Network, Myopia
- Trial name
- NCT06669728
- Testing
- AI diagnostic algorithm
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Spinal Anesthesia Induced Hypotension
COMPARISON BETWEEN EFFICACY OF NOREPINEPHRINE AND PHENYLEPHRINE BOLUSES for PREVENTION OF SPINAL ANAESTHESIA INDUCED HYPOTENSION IN OBSTETRICAL PATIENTS UNDERGOING EMERGENCY CESAREAN SECTION-A Double Blind Randomized Controlled Trial
The goal of this clinical trial is to learn if norepinephrine is more effective than phenylephrine for prevention of spinal anesthesia induced hypotension.
- Trial name
- NCT06836986
- Testing
- Norepinephrine Bolus, Phenylephrine bolus
- Where
- Pakistan
- Volunteers
- 124 people
- Sponsor
- Dow University of Health Sciences
ST Elevation Myocardial Infarction
Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With STEMI
The objective is to compare a reduced stent strategy based on drug-coated balloon (DCB) percutaneous coronary intervention (PCI) with conventional drug-eluting stent (DES) coronary revascularization in patients presenting with…
- Trial name
- COPERNICAN (NCT06353594)
- Testing
- Primary PCI
- Where
- 23 sites in Spain
- Volunteers
- 1,272 people
- Sponsor
- Hospital Universitario La Fe
STEMI, Large Thrombus Burden
Upfront Premedication For Reduction of Microvascular Obstruction and No-reflow in Treating ST-segment Elevation Myocardial Infarction
Angiographic no-reflow during primary PCI procedures occurs at relatively high rate (25%) and is associated with worsening of long term morbidity and mortality.
- Conditions
- STEMI, Large Thrombus Burden, No-Reflow Phenomenon
- Trial name
- UPFRONT-STEMI (NCT05393557)
- Testing
- Upfront preparation of microcirculation to minimize risks of no-reflow and reperfusion injury
- Volunteers
- 626 people
- Sponsor
- Cairo University
ST Elevation Myocardial Infarction, Non-ST Elevation Myocardial Infarction
IVUS Versus FFR for Non-infarct Related Artery Lesions in Patients With Multivessel Disease and Acute MI
The aim of the study is to compare clinical outcomes between intravascular ultrasound (IVUS)-guided treatment decision versus fractional flow reserve (FFR)-guided treatment decision for non-infarct related artery stenosis in…
- Trial name
- FRAME-AMI2 (NCT05812963)
- Testing
- IVUS-guided PCI group, FFR-guided PCI group
- Where
- 2 sites in South Korea
- Volunteers
- 1,400 people
- Sponsor
- Samsung Medical Center
Soccer Players
Q-Angle, Segment Length, Quadriceps, and Knee Alignment in Soccer Players
The aim of this study is to investigate the relationship of Q-angle, lower extremity segment lengths, and quadriceps muscle activation with dynamic knee alignment during a single-leg squat in active soccer players.
- Trial name
- NCT07894250
- Testing
- Group 1
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Suleyman Demirel University
Mitral Regurgitation
Artificial Intelligence Assisting Transcatheter Mitral Edge-to-Edge Repair
This multicenter, retrospective study develops and validates artificial intelligence (AI)-based semantic segmentation algorithms for intraprocedural transesophageal echocardiography (TEE) during Transcatheter Mitral Edge-to-Edge…
- Trial name
- AutoClip (NCT07632794)
- Where
- 3 sites in China, Italy
- Volunteers
- 1,500 people
- Sponsor
- Mi Chen
ST Segment Elevation Myocardial Infarction (STEMI), Cardiogenic Shock Post Myocardial Infarction
Early Beta Blocker Administration in STEMI Patients With SCAI B Status
This study is looking at how a medication called beta-blockers (metoprolol) affects patients with a heart attack (STEMI) who are in the cardiac intensive care unit.
- Trial name
- NCT06967194
- Testing
- Metoprolol (MET), Plcacebo
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cataract, Primary Angle-Closure Glaucoma
Anterior Segment Anatomy Assessed by Swept-Source OCT in Ocular Surgery Patients
This observational study aims to evaluate ocular anatomical parameters in patients undergoing anterior segment surgery using swept-source optical coherence tomography (SS-OCT).
- Trial name
- SS-OCT (NCT07903454)
- Testing
- Ocular anatomical parameters will be measured using a swept-source optical coherence tomography (SS-OCT) device (CASIA2; Tomey Corporation, Nagoya, Japan). The imaging examination will be used to asse
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Reperfusion Injury, Myocardial, Myocardial Infarction
Effect of L-Carnitine on Biomarkers of Myocardial Reperfusion Injury in Patients With STEMI
The study aims is to evaluate the efficacy and tolerability of L-Carnitine on biomarkers of myocardial reperfusion injury in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary PCI by the…
- Trial name
- NCT06564909
- Testing
- L-Carnitine, The standard care for the management of myocardial infarction post PCI
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Ain Shams University
Dental Implant
Accuracy of Guided Implant Placement Using Artificial Intelligence Segmentation Versus Conventional Technique
To compare the accuracy of surgical guided implant using AI tooth segmentation of the CBCT alone without intraoral scan to fabricate the implant guide versus conventional technique by alignment the CBCT and intraoral scan to…
- Trial name
- NCT06967090
- Testing
- Implant surgery using surgical guide
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Lung Cancer
ARtificial Intelligence for Gross Tumour vOlume Segmentation
Identifying the outline of a Gross Tumour Volume (GTV) in lung cancer is an essential step in radiation treatment. Clinical research, such as radiomics and image-based prognostication, requires the GTV to be pre-defined on…
- Trial name
- ARGOS (NCT05775068)
- Testing
- Radiotherapy
- Where
- Netherlands
- Volunteers
- 2,000 people
- Sponsor
- Maastricht Radiation Oncology
Myocardial Infarct, Remodeling, Left Ventricle
Heart Attack Blood Oxygen Therapy Trial
'Heart attack', known as acute ST-segment elevation myocardial infarction, is a leading cause of heart failure and death. A lack of blood and oxygen damages the heart muscle potentially causing heart failure and premature death.
- Trial name
- SSO2 Radial MI (NCT06662890)
- Testing
- Supersaturated oxygen
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- NHS National Waiting Times Centre Board
Macular Degeneration, Dry, Primary Open-angle Glaucoma
Retinal Photoreceptor Outer Segment Length Before and After Light Stimulation - a Pilot Study
It has been shown that reactions of human retinal photoreceptors to a light stimulus can be measured with custom-made, research prototype optical coherence tomography (OCT) systems.
- Trial name
- NCT03921931
- Testing
- White light stimulation
- Where
- Austria
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
STEMI - ST Elevation Myocardial Infarction
Noninvasive Artificial Venous Stasis for Reperfusion in STEMI
This prospective, randomized study was designed to evaluate whether the noninvasive artificial venous stasis / RE-START procedure, administered prior to primary percutaneous coronary intervention, increases the frequency of…
- Trial name
- RE-START (NCT07689591)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Firat University