Clinical trials: Seizures Disorders
Partial Epilepsy
Serotonin Receptors in Seizure Disorders
Patients in this study will undergo PET scans (a type of nuclear imaging test) to look for abnormalities in certain brain proteins associated with seizures.
- Trial name
- NCT00001932
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Seizures
Bioequivalency Study of Levetiracetam 1g Under Fasted Conditions
The objective of this study was to prove the bioequivalence of Levetiracetam 1000 mg Tablets under fasted conditions
- Trial name
- NCT00826722
- Testing
- Levetiracetam
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Febrile Seizure
A Cross-Sectional Study of Serum Levels of Adipocytokines in Children With Febrile Seizures
Febrile seizure (FS) is a common neurological condition in children, affecting 2 - 14% of children. FS is defined as seizures occurring in a child aged from six months to five years that is accompanied by a fever (≥38°C) without…
- Trial name
- NCT04967066
- Testing
- Serum Levels of Adipocytokines
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Febrile Seizure
Relationship Between Polymorphisms of TRPV1 and KCC2 Gene in Children With Febrile Seizures
Febrile seizures (FS) are the most common neurological disorder in chilhood. The etiology of FN is still the subject of numerous studies and it is known that it can depend on genetic predisposition.
- Trial name
- NCT04368936
- Testing
- Isolated DNA, Real Time PCR
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Institut za Rehabilitaciju Sokobanjska Beograd
Hearing Loss
Comparison of Hearing Aid Fitting Outcomes Between Self-fit and Professional Fit for MDHearing Smart Hearing Aids
Hearing aids are commonly used to help people with hearing loss hear better in daily listening environments. MDHearing Smart hearing aids are designed to use the MDHearing app to adjust hearing aids to each individual's hearing…
- Trial name
- NCT05165121
- Testing
- MDHearing smart hearing aid
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- MDHearingAid
Sensorineural Hearing Loss, Bilateral
Quantifying the Benefits and Cost-effectiveness of Real-Ear Measurements (REM) for Hearing Aid Fitting
Adjusting hearing aid user's real ear performance by using probe-microphone technology (real ear measurement, REM) has been a well-known procedure that verifies whether the output of the hearing aid at the eardrum matches the…
- Trial name
- BREM (NCT05621798)
- Testing
- Hearing Aid Manufacturer's Software, REM (Real Ear Measurements)
- Where
- Finland
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Epilepsy, Seizures
Bioequivalency Study of Oxcarbazepine 600 mg Tablets Under Fed Conditions
The objective of this study was to assess the bioequivalence of a potential generic 600 mg oxcarbazepine tablet formulation with Novartis Pharmaceutical's 600 mg oxcarbazepine tablet, Trileptal, folloiwng a single 600 mg dose…
- Trial name
- NCT00616863
- Testing
- Oxcarbazepine
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Hearing Loss
A Comparison of User-adjusted and Audiologist-adjusted Hearing Amplification
Fifty adults with mild to moderately severe sensorineural hearing loss will be fit with hearing amplification using two adjustment techniques.
- Trial name
- NCT03728907
- Testing
- Hearing aid fitting technique- audiologist or user-adjusted
- Volunteers
- healthy volunteers welcome
- Sponsor
- San Diego State University
Convulsion, Non-Epileptic
Retraining and Control Therapy (ReACT): Sense of Control and Symptom Expectations as Targets of a Treatment for PNES
The purpose of this study is to assess sense of control and catastrophic symptom expectations as targets for Retraining and Control Therapy (ReACT- an intervention focused on changing behaviors and thoughts) for treatment of…
- Trial name
- NCT05096273
- Testing
- ReACT
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Seizures
Crossover Bioequivalence Study of Oxcarbazepine 600 mg Suspension Under Fed Conditions
The objective of this study was to prove the bioequivalence of Roxane Laboratories' Oxcarbazepine Suspension 600 mg under fed conditions
- Trial name
- NCT01703468
- Testing
- Oxcarbazepine
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Epilepsy
The Effect of Sleep Hygiene Given to Epilepsy Patients on Seizure Frequency and Sleep Quality
Epilepsy is a disease that can be seen in everyone, including neurological, chronic, elderly and children. An estimated 50 million people in the world have epilepsy, patients have a history of two or more seizures, the exact…
- Trial name
- NCT06352476
- Testing
- Sleep Hygiene Training
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Marmara University
Prosthesis User, Orthopedic Disorder
Study of Patient Preferences in Relation to the Fitting of a Personalized and Connected Joint Prosthesis.
The goal of this observational study is to learn about patients' preference toward the use of customized and connected prosthesis.
- Trial name
- FKprefPat (NCT06100354)
- Testing
- Answering preference
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Epilepsies, Partial
MRI in Autosomal Dominant Partial Epilepsy With Auditory Features
This study will examine the possible structural and functional abnormalities in patients with an inherited form of epilepsy. It will use magnetic resonance imaging (MRI).
- Trial name
- NCT00072813
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Perinatal Death, Respiratory Distress Syndrome, Newborn
Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities
Hyperoxygenation for resuscitation of abnormal fetal heart rate tracings has been routine obstetric practice. However, there have not been any studies to support this practice.
- Conditions
- Perinatal Death, Respiratory Distress Syndrome, Newborn, Hypoxic-Ischemic Encephalopathy, Neonatal Seizure
- Trial name
- NCT03996317
- Testing
- Room air
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Epilepsy, Seizure Disorder
Policy on Optimal Epilepsy Management
This study examines the use of an online social media platform (PatientsLikeMe) to assist Veterans with epilepsy. The hypothesis is that the online social media platform, PatientsLikeMe, will improve selected patient-reported…
- Trial name
- POEM (NCT01762215)
- Testing
- PatientsLikeMe.com
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northern California Institute of Research and Education
Epilepsy, Status Epilepticus
Training Program to Improve EEG Competence
The goal of this clinical trial is to investigate the extent to which a practice-oriented training program for intensive care nursing staff and non-physician treatment teams can contribute to the earlier detection of epileptic…
- Conditions
- Epilepsy, Status Epilepticus, Status Epilepticus, Electrographic, Status Epilepticus, Non-Convulsive
- Trial name
- EPI-Train (NCT07689084)
- Testing
- Training Program
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital Marburg
Oxygen Toxicity, Hypercapnia
Oxygen Toxicity: Mechanisms in Humans
The goal of this clinical trial is to learn about the mechanisms of oxygen toxicity in scuba divers. The main questions it aims to answer are: How does the training of respiratory muscles affect oxygen toxicity? How do…
- Conditions
- Oxygen Toxicity, Hypercapnia, Seizures
- Trial name
- NCT05761756
- Testing
- Sleep Deprivation, Caffeine, Methylphenidate
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Duke University
Fever After Vaccination, Fever
Fever After Simultaneous Versus Sequential Vaccination in Young Children
A prospective, randomized open-label clinical trial that will be conducted during the 2017-2018 influenza season. During the 2017-2018 season, approximately 280 children will be enrolled at Duke University Medical Center and…
- Conditions
- Fever After Vaccination, Fever, Febrile Seizure
- Trial name
- NCT03165981
- Testing
- PCV13, DTaP, IIV
- Where
- 3 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Duke University
Febrile Convulsion
The Evaluation of the Effectiveness of Febrile Seizure Training Given to Parents
Objective: The aim of this study was to evaluate the effectiveness of a video-based educational intervention delivered via QR code to parents of hospitalized children aged 6 months to 5 years-an age group in which febrile…
- Trial name
- NCT07027501
- Testing
- The video based education group
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Single Seizure, Epilepsy
Seizure Recurrence After Unprovoked First Seizure
One in 10 people have a seizure during their life. Usually no cause is identified. Seizures without an identified cause are called unprovoked first seizure (UFS). Most people with UFS do not have further seizures.
- Trial name
- NCT05724719
- Where
- 2 sites in Canada
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Dr. Gavin Winston