Clinical trials: Selenium
Cancer
Selenium in the Prevention of Cancer
This is a pilot study proceeding an intended international trial. Hypothesis: Daily intake of selenium supplementation in the form of selenium-enriched yeast tablets will reduce the risk of cancer in healthy individuals.
- Trial name
- DK PRECISE (NCT01819649)
- Testing
- SelenoPRECISE selenium-enriched yeast tablet, Pharma Nord Denmark A/S
- Where
- Denmark
- Volunteers
- 491 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Cardiovascular Disease
Mussel Intake and Vitamin D Status in Humans
A significant proportion of the United Kingdom population have inadequate levels of vitamin D in their blood. Vitamin D is a fat-soluble vitamin that is essential for the growth and maintenance of healthy bones through increasing…
- Trial name
- Mussel (NCT02982525)
- Testing
- No Mussels, One mussel portion, Two mussel portions
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Fibromyalgia Syndrome, Anxiety
The Role of Bioelements in Fibromyalgia: Disease Activity or Depression-Anxiety?
The aim of this observational study was to determine the levels of serum bioelements in patients with fibromyalgia syndrome and to evaluate the relationship of these bioelements with disease activity, depression and anxiety.
- Conditions
- Fibromyalgia Syndrome, Anxiety, Depression
- Trial name
- NCT07519824
- Testing
- bioelements
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Pregnancy, Thyroid Autoimmune Disease
Potential Preventive Effect of Selenium on Iodine-induced Thyroid Autoimmunity During Pregnancy
In 1994, the WHO and UNICEF Joint Committee on Health Policy recommended Universal Salt Iodization as a safe, cost-effective and sustainable strategy to ensure sufficient intake of iodine by all individuals.
- Conditions
- Pregnancy, Thyroid Autoimmune Disease, Iodine Deficiency, Selenium Deficiency
- Trial name
- NCT03377218
- Testing
- Iodine, Iodine + Selenium
- Where
- Latvia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Riga Stradins University
Cardiovascular Mortality, Cardiac Function
Intervention With Selenium and Q10 on Cardiovascular Mortality and Cardiac Function in the Elderly Population in Sweden
The dietary supplements selenium and Q10 has been evaluated in a double blind placebo-controlled study in an elderly Swedish population.
- Trial name
- KiSel-10 (NCT01443780)
- Testing
- Selenium and ubiquinon (Q10) combined
- Where
- Sweden
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Pityriasis Versicolor
The Comparative Assessment of Mycological Efficacy, Safety, Recurrence, and Cost-effectiveness of Selenium Sulfide 1.8% Shampoo Versus Ketoconazole 2% Shampoo in Pityriasis Versicolor: a Double-blind Randomized Controlled Trial
There are several topical treatment for Pityriasis Versicolor including ketoconazole and selenium sulfide. Ketoconazole is a broad spectrum anti-fungal drug from imidazole group that has been reported to be effective in PV.
- Trial name
- NCT04007237
- Where
- Indonesia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Necrotic Pulp with Symptomatic Apical Periodontitis, Postoperative Dental Pain
Evaluation of Postoperative Pain and Antimicrobial Efficacy of Selenium Versus Calcium Hydroxide As Intracanal Medication in Mandibular First Molars with Necrotic Pulp and Symptomatic Apical Periodontitis
The main rational behind intracanal medicament is to kill the bacteria inside the root canal and to avert reinfection. In absence of nutrients, the bacteria remains after obturation in root canal may not survive.
- Conditions
- Necrotic Pulp with Symptomatic Apical Periodontitis, Postoperative Dental Pain, Antimicrobial Effect
- Trial name
- NCT06804330
- Testing
- root canal treatment and intracanal medicament
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Alzheimer Disease
Prevention of Alzheimer's Disease by Vitamin E and Selenium (PREADVISE)
The Prevention of Alzheimer's Disease by Vitamin E and Selenium (PREADVISE) prevention trial is an important addition to the Selenium and Vitamin E Cancer Prevention Trial (SELECT).
- Trial name
- NCT00040378
- Testing
- alphatocopherol, Selenium
- Where
- 91 sites in United States, Canada and 1 more
- Volunteers
- 4,246 people, healthy volunteers welcome
- Sponsor
- Frederick Schmitt
Cognitive Change, Nutrient Deficiency
Nutrition, Vision, and Cognition in Sport Study: Beef
The purpose of this study is to determine whether a 30 day beef intervention can improve peak cognitive performance in young, normally menstruating adult women.
- Conditions
- Cognitive Change, Nutrient Deficiency, Nutritional Anemia, Visual Spatial Processing
- Trial name
- IONSport:Beef (NCT04427852)
- Testing
- 30 day Daily consumption of 1 serving of beef, 30 day Daily consumption of 1 serving of the vegatable protein source
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Osteoporosis
Selenium for Musculoskeletal Health
This research aims to determine whether selenium supplements improve bone and muscle health in older women at risk of osteoporosis (low bone density or weak bones) and fracture (broken bones).
- Trial name
- NCT02832648
- Testing
- selenase (selenium)
- Where
- United Kingdom
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Methotrexate Spermatotoxicity
Impact of Selenium on Methotrexate Induced Spermatotoxicity; A Comparative Study
The aim of this study is to assess the potential protective role of selenium on semen parameters and its effect on seminal glutathione peroxidase level in patients on MTX therapy
- Trial name
- NCT06951282
- Testing
- Selenium, Methotrexate
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Abdominal Aneurysm, Selenium Deficiency
Selenium Levels in Patients With Abdominal Aneurysm
Retrospective study comparing the selenium level in patients with abdominal aortic aneurysm with the selenium level in patients in the control group, i.e., patients without aneurysmal changes of the abdominal aorta.
- Trial name
- NCT07236281
- Where
- Slovakia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Comenius University
Generalized Epileptic
Study on Serum Zinc and Selenium Levels in Epileptic Patients
This study was carried out with the purpose of evaluating zinc and selenium levels in serum of epileptic patients and compare with normal individuals.
- Trial name
- NCT01764516
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Arak University of Medical Sciences
Diet, Vegan, Selenium
Improvement of the Selenium Supply in a Vegan Diet by Different Selenium Sources
As vegans are among the individuals with the lowest serum selenium levels, the randomized controlled SelVeg study aims to address the question of whether Brazil nuts could be an adequate source of selenium for diets potentially…
- Trial name
- SelVeg (NCT05814874)
- Testing
- selenium supplement, Brazil nut
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Jena
Selenium Supplementation, Influenza Vaccination
Effect of Selenium Supplementation on Influenza Vaccination
The study is designed to assess whether selenium supplementation can boost the immunity response to influenza vaccination in healthy adults.
- Trial name
- NCT04188483
- Testing
- Selenium Supplementation, Influenza vaccination
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Nutrition, Healthy
Selenium Biofortification of Strawberries
This study aims to investigate the effects of a nutritional intervention with selenium-biofortified strawberries on glucose homeostasis and hepatic function of healthy individuals.
- Trial name
- SeStra30Days (NCT06875674)
- Testing
- supplementation with control strawberry, supplementation with biofortified strawberry, supplementation with selenium in tablet
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Cadmium Body Burden
Crabmeat and Health Study
The brown meat from crab may contain high levels of the heavy metal cadmium. Cadmium is found in the environment and long-term exposure can cause accumulation in the body.
- Trial name
- NCT03104530
- Testing
- Brown crabmeat
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Food Sensory Perception, Selenium Status
Investigating the Sensory Effects of Selenium-enriched Parsnips.
Study aims to investigate 2 topics: 1. Flavour-Nutrient Learning (FNL) FNL proposes that personal food preferences may be influenced by unconscious mechanisms which operate to ensure the safeguarding of individual nutrient…
- Trial name
- NCT03219853
- Testing
- selenium enriched parsnips, Conventional parsnips
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Arsenic Poisoning
High-selenium Lentils Versus Arsenic Toxicity
About 45 million people in Bangladesh are chronically exposed to unacceptable levels of arsenic in their drinking water. Chronic arsenic poisoning leads to cancers, and vascular diseases.
- Trial name
- NCT02429921
- Testing
- high-selenium lentils, Low-Se lentils
- Where
- Bangladesh
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Selenium Status
Investigating the Sensory Attributes of Selenium-fortified Biscuits and Their Effects on Selenium-status
This intervention study will investigate the relationship between consumption of selenium-fortified biscuits fortified with selenium-enriched yeast (approximately 60mcg of selenium per day for 14 days) and both plasma selenium…
- Trial name
- NCT03770676
- Testing
- Selenium-fortified biscuits
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Newcastle University