Clinical trials: Selenium
Scalp Dermatitis, Dermatitis
Effects on the Scalp Microbiota of a 1% Selenium Disulfide and 1% Salicylic Acid Shampoo After 2% Ketaconazole Foaming Gel Treatment for Scalp Seborrheic Dermatitis
The aim of this study was to investigate the changes in the scalp bacterial and fungal microbiota in subjects afflicted with a scalp seborrheic dermatitis (SSD) during a 2% ketoconazole-based treatment followed by a maintenance…
- Trial name
- NCT04057950
- Testing
- cosmetic product
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Selenium Deficiency
Optimization of Selenoprotein P in Chinese Subjects
The purpose of this study is to determine the amount of selenium as selenomethionine that is required to optimize selenoprotein P in selenium-deficient Chinese subjects
- Trial name
- NCT00428649
- Testing
- 20 µg selenium, 40 µg selenium, 60 µg selenium
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Colorectal Cancer, Adenomatous Colorectal Polyps
Selenium for Prevention of Adenomatous Colorectal Polyps
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. Selenium may be effective in preventing the recurrence of adenomatous colorectal polyps.
- Conditions
- Colorectal Cancer, Adenomatous Colorectal Polyps, Precancerous Condition
- Trial name
- NCT00078897
- Testing
- Selenium
- Where
- 7 sites in United States
- Volunteers
- 1,621 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Nutritional Requirements
Predicting Dietary Selenium Needs to Achieve Target Blood Selenium Levels
In this study, we will evaluate the effectiveness of several doses of oral selenomethionine in raising biomarkers of selenium status including plasma selenium concentrations.
- Trial name
- LoDoSe (NCT00803699)
- Testing
- selenium as L-selenomethionine
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Arsenic Poisoning Chronic
Selenium and Arsenic Pharmacodynamics
This clinical trial should prove that selenium can treat arsenic exposure in humans by promoting excretion. The new trial differs from previous trials in that participants will be maintained in a local clinic and provided with…
- Trial name
- SEASP (NCT02377635)
- Testing
- Anhydrous selenite, Sodium chloride
- Where
- Bangladesh
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Chagas Disease
Selenium Treatment and Chagasic Cardiopathy (STCC)
Background: Chagasic myocardiopathy caused by the protozoa Trypanosoma cruzi has been the principal cause of cardiac death in Latin America.
- Trial name
- STCC (NCT00875173)
- Testing
- Selenium
- Where
- Brazil
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Oswaldo Cruz Foundation
Prevention of Colorectal Cancer
Colon Cancer Prevention Using Selenium
Selenium's ability to prevent colorectal cancer (CRC) has been suspected for nearly 30 years, but has never been directly studied in humans.
- Trial name
- NCT01211561
- Testing
- Selenium, selenomethionine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Immunity, Vaccine Reaction
Efficacy and Tolerability of ABBC1 in Volunteers Receiving the Influenza or Covid-19 Vaccine
The immune system response needs to be forceful but also balanced for a rapid recovery from infection which avoids harmful overreactions.
- Conditions
- Immunity, Vaccine Reaction, Influenza, Covid19
- Trial name
- NCT04798677
- Testing
- ABBC1 Immunoessential
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AB Biotek
Healthy, Liver Cirrhosis
Selenium Supplementation of Patients With Cirrhosis
The purpose of this study is to determine whether patients with liver disease can improve their nutritional selenium status by taking supplemental selenium.
- Trial name
- NCT00212186
- Testing
- Selenium Supplements (essential nutrient)
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Cervical Intraepithelial Neoplasia (CIN), Cervical Cancer
Correlation Between Selenium Levels in Human Tissues and HPV-related Cervical Lesions and Outcomes
This study investigates the relationship between selenium levels in human tissues and the persistence of HPV (human papillomavirus) infection, particularly focusing on cervical-related lesions.
- Conditions
- Cervical Intraepithelial Neoplasia (CIN), Cervical Cancer, Persistent HPV Infection
- Trial name
- SeHPV (NCT06665841)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Breast Cancer Risk
Soy, Selenium and Breast Cancer Risk
There is evidence to suggest that some dietary components can reduce the risk of breast cancer. In this pilot study two such components, isoflavones (compounds found in soy products) and selenium, will be given to women classed…
- Trial name
- NCT00555386
- Testing
- Soy and Selenium
- Where
- 3 sites in United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Effect of Selenium on Oxidative Stress in Healthy Men
Influence of Selenium on Prostate Cancer Related Biomarkers
Penn State Milton S. Hershey Medical Center researchers are trying to compare the effects of two different forms of selenium (selenium yeast and selenomethionine) on blood selenium levels and biomarkers of oxidative stress as…
- Trial name
- NCT01112449
- Testing
- selenomethionine, low dose selenized-yeast, high dose selenized-yeast
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Peripartum Cardiomyopathy
Peripartum Cardiomyopathy in Nigeria Registry
Peripartum cardiomyopathy (PPCM) is a global disease with significant morbidity and mortality, and Nigeria probably has the highest burden of the disease in the world.
- Trial name
- PEACE (NCT03081949)
- Testing
- Oral Sodium Selenite 200 µg/day for 3 months
- Where
- 2 sites in Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aminu Kano Teaching Hospital
Healthy
Selenium and Immune Function
The aim of the study is to investigate the relationship between dose and form of selenium on immune function, and to identify functional markers of selenium status.
- Trial name
- NCT00279812
- Testing
- 50ug selenium enriched yeast, 100ug selenium enriched yeast, 200ug selenium enriched yeast
- Where
- United Kingdom
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Inflammation
Effect of Selenium Intervention on Inflammation in Older Adults
Serum levels of inflammatory mediators increase with age and are strongly associated with the most common and the most devastating health conditions found in older adults including frailty, chronic disease, disability and…
- Trial name
- NCT01289925
- Testing
- Selenium
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Acute Kidney Injury
Effect of Vitamin E+Selenium on Kidney Function in Controlled Hypotension
The purpose of this study is to determine whether Kidney injury happens in controlled hypotension during brain operations by using Neutrophil Gelatinase Associated Lipocalin ELISA Kit and if so, does VitaminE+Selenium prevent it
- Trial name
- NCT01554345
- Testing
- vitamin E +Selenium
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Colorectal Cancer, Precancerous Condition
S0000D: Effect of Vitamin E and/or Selenium on Colorectal Polyps in Men Enrolled on SELECT Trial SWOG-S0000
RATIONALE: Studying tissue samples in the laboratory from participants receiving treatment on the Selenium and Vitamin E Cancer Prevention Trial (SELECT) SWOG-S0000 may help doctors predict a participant's response to treatment…
- Trial name
- ACP (NCT00706121)
- Testing
- Vitamin E, Selenium
- Where
- United States
- Volunteers
- 8,094 people, healthy volunteers welcome
- Sponsor
- SWOG Cancer Research Network
Selenium and Iodine Status
Contribution of Cow's Milk to Iodine and Selenium Status in Women of Child-bearing Age
Iodine is an essential trace element necessary for the synthesis of thyroid hormones which are critical for human growth and development throughout the lifecycle.
- Trial name
- SIMI (NCT02767167)
- Testing
- Semi-skimmed cow's milk
- Where
- United Kingdom
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Chronic Obstructive Pulmonary Disease, Lung Diseases
Supplemental Selenium and Vitamin E and Pulmonary Function
To test whether supplementation with selenium and/or vitamin E affects pulmonary function.
- Conditions
- Chronic Obstructive Pulmonary Disease, Lung Diseases, Lung Diseases, Obstructive
- Trial name
- NCT00063453
- Testing
- Vitamin E, Selenium
- Volunteers
- 2,920 people, healthy volunteers welcome
- Sponsor
- Cornell University