Clinical trials: Selenium
Thyroid Associated Ophthalmopathies
Selenium in Mild Thyroid Eye Disease in North America
The purpose of this study is to determine whether sodium selenite is helpful in the treatment of mild thyroid eye disease in North America.
- Trial name
- S-ITEDS (NCT02112643)
- Testing
- Sodium selenate, Sugar pill
- Sponsor
- Columbia University
Pregnancy, Thyroid Autoimmune Disease
Potential Preventive Effect of Selenium on Iodine-induced Thyroid Autoimmunity During Pregnancy
In 1994, the WHO and UNICEF Joint Committee on Health Policy recommended Universal Salt Iodization as a safe, cost-effective and sustainable strategy to ensure sufficient intake of iodine by all individuals.
- Conditions
- Pregnancy, Thyroid Autoimmune Disease, Iodine Deficiency, Selenium Deficiency
- Trial name
- NCT03377218
- Testing
- Iodine, Iodine + Selenium
- Where
- Latvia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Riga Stradins University
QoL Before and After 9 Month of Medical Treatment of Graves´Thyrotoxicosis, Potential Effect of Selenium
Neuropsychologic and Immunological Evaluation in Treatment of Thyroid Diseases. Is Selenium Efficient?
Graves thyrotoxicosis is a common autoimmune disease. Patients suffer at diagnosis from weight loss, increased heart rate and stress intolerance. Some patients have difficulties in regaining quality of life.
- Trial name
- NCT01247077
- Testing
- selenium
- Where
- 2 sites in Sweden
- Volunteers
- 44 people
- Sponsor
- Karolinska Institutet
Lichen Planus, Oral
The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen Planus
evaluate clinically and biochemically the efficacy of topically applied selenium as complementary or alternative to triamcinolone acetonide 0.1% and tacrolimus 0.1% in patients with oral lichen planus.
- Trial name
- RCT (NCT06362005)
- Testing
- Triamcinolone Acetonide 0.1% Oint, Tacrollimus Topical, Selenium
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Breast Cancer Risk
Soy, Selenium and Breast Cancer Risk
There is evidence to suggest that some dietary components can reduce the risk of breast cancer. In this pilot study two such components, isoflavones (compounds found in soy products) and selenium, will be given to women classed…
- Trial name
- NCT00555386
- Testing
- Soy and Selenium
- Where
- 3 sites in United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Scalp Dermatitis, Dermatitis
Effects on the Scalp Microbiota of a 1% Selenium Disulfide and 1% Salicylic Acid Shampoo After 2% Ketaconazole Foaming Gel Treatment for Scalp Seborrheic Dermatitis
The aim of this study was to investigate the changes in the scalp bacterial and fungal microbiota in subjects afflicted with a scalp seborrheic dermatitis (SSD) during a 2% ketoconazole-based treatment followed by a maintenance…
- Trial name
- NCT04057950
- Testing
- cosmetic product
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Lung Cancer
Carboplatin, Paclitaxel, Selenomethionine, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery
RATIONALE: Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00526890
- Testing
- selenomethionine, carboplatin, paclitaxel
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Roswell Park Cancer Institute
Unspecified Adult Solid Tumor, Protocol Specific
Irinotecan and Selenium in Treating Patients With Advanced Solid Tumors
RATIONALE: Drugs used in chemotherapy, such as irinotecan, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00112892
- Testing
- selenium, irinotecan hydrochloride
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Roswell Park Cancer Institute
Childhood Obesity
Efficacy Evaluation of a Mixed Compound of Antioxidants in Terms of Endothelium Damage/Function in Pediatric Subjects With Obesity.
The aim of our study was to test the effects on endothelium of a combination of curcumin, resveratrol, plus zinc, magnesium, selenium and Vitamin D in a cohort of pediatric subjects with obesity.
- Trial name
- OBELIX (NCT04723849)
- Testing
- Auxilie® Immuplus, Envicon Medical, Verona, Italy
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Universita di Verona
Cancer of the Prostate, Prostate Cancer
Study of Antioxidants on Prostate Tumors in Men Undergoing Radical Prostatectomy for Prostate Cancer
The purpose of this study is to see if an intervention of antioxidants(vitamin E, selenium and lycopene) can change (reduce) prostate tumor size and alter certain markers that can affect tumor growth and prostate cancer…
- Conditions
- Cancer of the Prostate, Prostate Cancer, Prostatic Neoplasms
- Trial name
- NCT00844792
- Testing
- Lycopene, Vitamin D3, Selenium, Green Tea Extract, Vitamin E
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University Health Network, Toronto
Autoimmune Thyroiditis
Selenium Supplementation in Autoimmune Thyroiditis
Our aim is to investigate if selenium supplementation versus placebo adjuvant to the standard treatment with levothyroxine (LT4) in patients with autoimmune thyroiditis will lead to improved thyroid specific quality of life, and…
- Trial name
- CATALYST (NCT02013479)
- Testing
- SelenoPRECISE
- Where
- 4 sites in Denmark
- Volunteers
- 415 people
- Sponsor
- Steen Bonnema
Selenium
Study on the Effect of Selenium Supplementation on the Structure and Function of Autoimmune Thyroiditis
To evaluate the effects of exogenous selenium supplementation on autoimmune thyroiditis.
- Trial name
- NCT04942769
- Testing
- Selenium
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Chao Yang Hospital
Heart Failure, Heart Failure and Reduced Ejection Fraction
Selenium Intervention Registry Randomized Trial in Heart Failure
Heart failure is a serious condition in which the heart is unable to pump blood effectively, and it remains a leading cause of hospitalization and death worldwide despite advances in treatment.
- Conditions
- Heart Failure, Heart Failure and Reduced Ejection Fraction, Heart Failure and Mildly Reduced Ejection Fraction, Heart Failure and Preserved Ejection Fraction
- Trial name
- SIRI-HF (NCT07543562)
- Testing
- Selenium Supplement
- Where
- 11 sites in Norway, Sweden
- Volunteers
- 4,326 people
- Sponsor
- Skane University Hospital
Selenium Deficiency
Research on Association Between Selenium Deficiencies and Change of Thyroid Function
As one of the essential micronutrients, selenium has important biological functions. However, an effective and convenient method for evaluation of selenium nutritional status has not yet been established.
- Trial name
- NCT03448588
- Testing
- detection of serum selenium
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Trace Element Excess
Chromium Contamination of Parenteral Nutrition
It has been observed that patients on total parenteral nutrition (TPN) have high plasma chromium level. There is reason to believe that TPN solutions contain chromium and possibly other trace elements as contaminants.
- Trial name
- NCT03906890
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- The Hospital for Sick Children
Heart Failure
A Danish Pragmatic Randomized Trial of Nutritional Supplements in Heart Failure
Heart failure is a common and serious condition. Despite rapid advancements in heart failure treatment, the prognosis remains severe.
- Trial name
- DANUTRIO-HF (NCT06694727)
- Testing
- Coenzyme Q10 100 Milligrams Oral Capsule, Selenium 100 Micrograms Oral Tablets
- Where
- Denmark
- Volunteers
- 4,044 people
- Sponsor
- Tor Biering-Sørensen
Selenium Deficiency
Prospective, Non-randomized Observational Trial of Selenium in Cardiac Surgery
In this observational study the effect of selenium supplementation on the postoperative inflammatory response and clinical course should be examined in (approximately 100) adult patients undergoing elective heart surgery combined…
- Trial name
- SICS (NCT01394068)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Healthy, Liver Cirrhosis
Selenium Supplementation of Patients With Cirrhosis
The purpose of this study is to determine whether patients with liver disease can improve their nutritional selenium status by taking supplemental selenium.
- Trial name
- NCT00212186
- Testing
- Selenium Supplements (essential nutrient)
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Ischemic Stroke
Selenium and Ischemic Stroke Outcome
Selenium is a trace element essential to human health.Selenium protection against cellular damage by oxygen radicals is accomplished through selenoproteins.
- Trial name
- NCT02505295
- Testing
- Selenium, normal saline
- Where
- Iran
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mazandaran University of Medical Sciences
Chronic Obstructive Pulmonary Disease, Cardiovascular Disease
Selenium Supplementation in Chronic Obstructive Pulmonary Disease (COPD) Patients
Does an oral selenium supplement increase blood levels of antioxidants in patients with established, smoking-related lung disease? Members of our study group recently discovered that elevated levels of the anti-oxidant GPx-1 may…
- Trial name
- NCT00186706
- Testing
- Selenium
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- St. Joseph's Health Care London