Clinical trials: Selenium Supplementation
Dietary Selenium Deficiency, Dietary Zinc Deficiency
Zinc and Selenium Supplementation in Atherosclerosis
The aim of this randomized double-blind study was to evaluate the effect of oral zinc and selenium supplementation on oxidative stress and inflammation biomarkers as well as the status of zinc and selenium in patients with…
- Trial name
- NCT01547377
- Testing
- zinc and selenium supplementation
- Where
- Brazil
- Volunteers
- 76 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Selenium Supplementation, Influenza Vaccination
Effect of Selenium Supplementation on Influenza Vaccination
The study is designed to assess whether selenium supplementation can boost the immunity response to influenza vaccination in healthy adults.
- Trial name
- NCT04188483
- Testing
- Selenium Supplementation, Influenza vaccination
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Autoimmune Thyroiditis
Selenium Supplementation in Youths With Autoimmune Thyroiditis
To investigate whether the supplementation of organic selenium at the "adult" dose (200 mcg per day in the form of L-selenomethionine) has a favorable impact on thyroid function, including the titer of anti-thyroid antibodies…
- Trial name
- THYROSEL (NCT02644707)
- Testing
- L-selenomethionine
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Myalgic Encephalomyelitis
Effect of CoQ10 Plus Selenium Supplementation on Clinical Outcomes and Biochemical Markers in ME/CFS (CoSeME Study)
In recent years, it has been suggested that nutritional deficiencies may be of causal relevance in individuals with ME/CFS. These include deficiencies of vitamins and trace elements.
- Trial name
- CoSeME (NCT05128292)
- Testing
- CoQ10 plus Selenium
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Prostate Cancer
Selenomethionine in Treating Patients Undergoing Surgery or Internal Radiation Therapy for Stage I or Stage II Prostate Cancer
RATIONALE: Selenomethionine may slow the growth of prostate cancer. Giving selenomethionine before surgery or internal radiation therapy may be an effective treatment for prostate cancer.
- Trial name
- NCT00736164
- Testing
- selenomethionine
- Sponsor
- Roswell Park Cancer Institute
Type 2 Diabetes Mellitus
Vitamin C Supplementation Plus Hypoglycemic Agents Versus Hypoglycemic Agents Alone in Type 2 Diabetes Mellitus
Null hypothesis: No significant effect of vitamin C 500 mg Supplementation on the severity of micro-vascular complications of type 2 Diabetes Mellitus (DM).
- Trial name
- Vit C (NCT01319734)
- Testing
- Vitamin C, glyburide
- Where
- Sudan
- Volunteers
- 50 people
- Sponsor
- Al-Neelain University
Osteoporosis
Selenium for Musculoskeletal Health
This research aims to determine whether selenium supplements improve bone and muscle health in older women at risk of osteoporosis (low bone density or weak bones) and fracture (broken bones).
- Trial name
- NCT02832648
- Testing
- selenase (selenium)
- Where
- United Kingdom
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Inflammation, Malnutrition
Effect of Selenium Supplementation on Inflammatory,Oxidative and Nutritional Markers in Hemodialysis Patients
The aim of this study is to evaluate the effect of selenium supplementation on oxidative, inflammatory and nutritional markers in hemodialysis patients.
- Conditions
- Inflammation, Malnutrition, Complication of Hemodialysis
- Trial name
- NCT01147354
- Testing
- selenium yeast
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Zahra Sohrabi
Ulcerative Colitis (UC)
Selenium Supplementation in Moderate-Severely Active Ulcerative Colitis Patients Treated With Advanced Therapies
Micronutrient deficiencies are common in ulcerative colitis (UC). Selenium deficiency is associated with worse disease outcomes including disease flares and need for surgery.
- Trial name
- Selenium-UC (NCT07427017)
- Testing
- Selenium supplementation
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Northwestern University
Ventricular Dysfunction, Left
High-dose Selenium Supplementation in Patients With Left Ventricular Assist
This planned pilot study is a monocentric, prospective, double-blind randomized and placebo controlled clinical study. The SOS-LVAD Trial can be assigned to the clinical Phase III.
- Trial name
- SOS-LVAD (NCT02530788)
- Testing
- Selenium Supplement (sodium selenite)
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- RWTH Aachen University
Depression - Major Depressive Disorder
Selenium Supplementation for Improving Depression in Children and Adolescents: Efficacy and Mechanistic Study
The purpose of this study is to investigate the role and mechanisms of selenium in depression among children and adolescents, aiming to provide new insights for understanding the pathogenesis and treatment of depression in this…
- Trial name
- NCT07203144
- Testing
- selenium yeast supplementation
- Where
- China
- Volunteers
- 172 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Oxidative Stress, Inflammation
Effect of Selenium on Serum Adiponectin, Homocystein and Malnutrition-inflammation Complex Syndrome in Hemodialysis Patients
The aim of this study is to determine the effect of selenium supplementation as an antioxidant on serum adiponectin, HSCRP , ferritin , transferrin, albumin and homocysteine level.
- Conditions
- Oxidative Stress, Inflammation, Malnutrition
- Trial name
- NCT01150786
- Testing
- Selenium Supplement
- Where
- 2 sites in Iran
- Volunteers
- 80 people
- Sponsor
- maryam ekramzadeh
Type 2 Diabetes
Effects of Selenium Towards Type 2 Diabetes
According to the prevalence of non-communicable chronic diseases and aging population characteristics, this study is exploring the coexist effects combined with various dimensions: nutritional functions, metabolic homeostasis…
- Trial name
- NCT06457984
- Testing
- Selenium nutritional supplementation
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Pregnancy, Thyroid Autoimmune Disease
Potential Preventive Effect of Selenium on Iodine-induced Thyroid Autoimmunity During Pregnancy
In 1994, the WHO and UNICEF Joint Committee on Health Policy recommended Universal Salt Iodization as a safe, cost-effective and sustainable strategy to ensure sufficient intake of iodine by all individuals.
- Conditions
- Pregnancy, Thyroid Autoimmune Disease, Iodine Deficiency, Selenium Deficiency
- Trial name
- NCT03377218
- Testing
- Iodine, Iodine + Selenium
- Where
- Latvia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Riga Stradins University
Autoimmune Thyroiditis
Selenium Supplementation in Autoimmune Thyroiditis
Our aim is to investigate if selenium supplementation versus placebo adjuvant to the standard treatment with levothyroxine (LT4) in patients with autoimmune thyroiditis will lead to improved thyroid specific quality of life, and…
- Trial name
- CATALYST (NCT02013479)
- Testing
- SelenoPRECISE
- Where
- 4 sites in Denmark
- Volunteers
- 415 people
- Sponsor
- Steen Bonnema
Selenium
Study on the Effect of Selenium Supplementation on the Structure and Function of Autoimmune Thyroiditis
To evaluate the effects of exogenous selenium supplementation on autoimmune thyroiditis.
- Trial name
- NCT04942769
- Testing
- Selenium
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Chao Yang Hospital
Heart Failure, Heart Failure and Reduced Ejection Fraction
Selenium Intervention Registry Randomized Trial in Heart Failure
Heart failure is a serious condition in which the heart is unable to pump blood effectively, and it remains a leading cause of hospitalization and death worldwide despite advances in treatment.
- Conditions
- Heart Failure, Heart Failure and Reduced Ejection Fraction, Heart Failure and Mildly Reduced Ejection Fraction, Heart Failure and Preserved Ejection Fraction
- Trial name
- SIRI-HF (NCT07543562)
- Testing
- Selenium Supplement
- Where
- 11 sites in Norway, Sweden
- Volunteers
- 4,326 people
- Sponsor
- Skane University Hospital
Healthy, Liver Cirrhosis
Selenium Supplementation of Patients With Cirrhosis
The purpose of this study is to determine whether patients with liver disease can improve their nutritional selenium status by taking supplemental selenium.
- Trial name
- NCT00212186
- Testing
- Selenium Supplements (essential nutrient)
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Ischemic Stroke
Selenium and Ischemic Stroke Outcome
Selenium is a trace element essential to human health.Selenium protection against cellular damage by oxygen radicals is accomplished through selenoproteins.
- Trial name
- NCT02505295
- Testing
- Selenium, normal saline
- Where
- Iran
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mazandaran University of Medical Sciences
Chronic Obstructive Pulmonary Disease, Cardiovascular Disease
Selenium Supplementation in Chronic Obstructive Pulmonary Disease (COPD) Patients
Does an oral selenium supplement increase blood levels of antioxidants in patients with established, smoking-related lung disease? Members of our study group recently discovered that elevated levels of the anti-oxidant GPx-1 may…
- Trial name
- NCT00186706
- Testing
- Selenium
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- St. Joseph's Health Care London