Clinical trials: Self-Injurious Behavior, open to volunteers
Suicide, Suicide Ideation
Randomized Suicide Prevention Trial Using ASSIP and ACT in Suicide Attempters
This is a randomized controlled trial that aims to compare the effectiveness of two psychological treatment approaches: the Attempted Suicide Short Intervention Program (ASSIP) and Acceptance and Commitment Therapy (ACT).
- Trial name
- NCT07132099
- Testing
- Attempted Suicide Short Intervention Program (ASSIP), Acceptance and Commitment Therapy (ACT), Treatment as Usual (TAU)
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Ardakan University
Depression, Suicidality
Sleep Health in U.S. Marines
The goal of this study is to test a sleep health program designed specifically for U.S. Marine Corps personnel. Researchers want to determine if this program helps Marines improve the participants sleep quality and overall mental…
- Conditions
- Depression, Suicidality, Sleep
- Trial name
- NCT07420205
- Testing
- Sleep Leadership, Circadian, Light, and Sleep Skills in Shipboard Military (CLASS-MC) Personnel Program, Insomnia Coach
- Where
- United States
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Suicidal Ideation, Major Depressive Episode
Add-on Buprenorphine at Analgesic Doses for the Treatment of Severe Suicidal Ideas During a Major Depressive Episode
This study aims at investigating if adjunctive buprenorphine at low dose to treatment as usual is effective in reducing severe suicidal ideas in major depressive episode, and at determining the most effective dose.
- Trial name
- BUPRIS (NCT03646058)
- Testing
- Buprenorphine
- Where
- 9 sites in France
- Volunteers
- 180 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Suicide Prevention, Suicide Risk | Patient
Pilot Testing Suicide Risk Prediction Algorithms in Primary Care
The goal of this pilot study is to learn whether the use of suicide risk prediction algorithms in primary care can help identify people who may benefit from extra mental health monitoring.
- Trial name
- NCT07068685
- Testing
- Suicide risk prediction algorithm
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Suicide
Text-based Support for Parents of Adolescents Following an Emergency Department Visits
The goal of this study is to determine the effectiveness of an adaptive text-based intervention for parents of adolescents seeking emergency department services for suicide risk concerns.
- Trial name
- TESP (NCT06660199)
- Testing
- Text-based intervention
- Where
- 2 sites in United States
- Volunteers
- 420 people
- Sponsor
- University of Michigan
Suicide, Suicidal Ideation
Safety Planning Intervention Telehealth Service Model in Emergency Departments
The purpose of this study is to evaluate the effectiveness and implementation of a suicide prevention strategy delivered via telehealth in Emergency Departments.
- Trial name
- NCT05307432
- Testing
- SPI+ Delivered by ED Staff, SPI+ Delivered by SPCC Clinicians
- Where
- United States
- Volunteers
- 2,814 people
- Sponsor
- University of Pennsylvania
Suicide Ideation, Suicide Attempts
Brief Cognitive Behavioral Therapy for Suicide Prevention in a Brazilian Sample: a Study Protocol of a Randomized Clinical Trial
The vast majority of suicides occur in low-and middle-income countries (LMICs), and evidence on effective psychotherapeutic interventions to prevent suicide that are culturally adapted to these contexts is limited.
- Trial name
- NCT07574658
- Testing
- Brief Cognitive-Behavioral Therapy (BCBT) for Suicide Prevention, Supportive Therapy
- Volunteers
- 150 people
- Sponsor
- University of Sao Paulo
Suicidal Ideation, Suicide Attempt
Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial
This study outlines a randomized controlled trial evaluating two brief suicide-specific interventions for adolescents aged 12-17 who are hospitalized for suicidal ideation or attempts.
- Conditions
- Suicidal Ideation, Suicide Attempt, Safety Plan, Depression / Major Depressive Disorder
- Trial name
- NCT07628192
- Testing
- CAMS Brief Intervention, Stanley-Brown Safety Planning Intervention
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- The Cleveland Clinic
Nonsuicidal Self Injury, Nonsuicidal Self-Injury
Psychological Treatment for Adolescents With Self-injury Within Intensive Mental Health Outpatient Services: Randomized Controlled Pilot Trial
The overarching aim of this study is to develop and evaluate a new blended treatment format, which combines face-to-face and digital treatment components, for Emotion Regulation Individual Therapy for Adolescents (ERITA).
- Conditions
- Nonsuicidal Self Injury, Nonsuicidal Self-Injury, Self-Harm
- Trial name
- NCT07755774
- Testing
- Blended ERITA, Treatment as Usual (TAU), Concomitant care
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Nonsuicidal Self-Injury
Trial to Evaluate the Effects of Naltrexone in Nonsuicidal Self-injury
The goal of this clinical trial is to learn if naltrexone works to treat nonsuicidal self-injurious behavior in adolescents and adults.
- Trial name
- NiNsSIB (NCT06622239)
- Testing
- Naltrexone
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Self Harm
PsiloIMAGINE: A Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm
Approximately 20% of young people experience self-harm behaviour in their lives. Self-harm can occur across different mental health disorders, and lead to negative outcomes and risk of suicide.
- Trial name
- PsiloIMAGINE (NCT06798636)
- Testing
- Psilocybin 5 mg with cognitive behavioural therapy intervention
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Self Harm, Suicide, Attempted
Emotional Dysregulation in Para-suicidal Behavior
This is a naturalistic cohort pre-post study investigating aspects of emotional processing and how possible changes in emotional processing is related to the successful treatment of non-suicidal self-injury and suicidal ideation…
- Conditions
- Self Harm, Suicide, Attempted, Emotional Instability, Borderline Personality Disorder
- Trial name
- NCT03846375
- Testing
- Psychotherapy, Pre-intervention testing
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Aggression, Self-injurious Behavior
Refinements of Functional Communication Training
Although treatments for problem behavior, like functional communication training (FCT), can be highly effective in the clinic, changes in the way the FCT is implemented (e.g., when transferring treatment to the home, when…
- Trial name
- NCT04045600
- Testing
- Trad FCT, Mult FCT, Mult FCT + Stimulus Fading
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Rutgers, The State University of New Jersey
Suicidal Ideation, Treatment-resistant Depression
Cortical Inhibition as a Biomarker of Response in a Comparison of Bilateral Versus Unilateral Accelerated Theta Burst Stimulation for Suicidal Ideation in Treatment-Resistant Depression -COMBAT-SI
This is a prospective clinical trial to confirm the effectiveness of bilateral accelerated theta burst stimulation (aTBS) on suicidal ideation (SI), while exploring cortical inhibition measures in this treatment paradigm.
- Trial name
- COMBAT-SI (NCT05377177)
- Testing
- Accelerated Theta Burst Stimulation
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of California, San Diego
Posttraumatic Stress Disorder (PTSD), Suicidal Ideation
Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD
The purpose of this research is to see if Crisis Response Planning (CRP), a brief strategy designed to help people cope effectively with emotional crises, combined with Cognitive Processing Therapy (CPT), a talk treatment for…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Suicidal Ideation, Suicide Attempt
- Trial name
- mCPT+CRP (NCT07238192)
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Ohio State University
Suicidal Ideation, Regulation, Emotion
Effect of Morning Light Exposure on Mood
Mood dysregulation and suicidal ideation are closely associated with disruption of sleep and circadian rhythms. Moreover, sleep problems and circadian disruption are commonplace features of military life.
- Trial name
- NCT05616819
- Testing
- Active light exposure
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Prevention of Suicidal Behavior
Impact of a High-resolution Program for the Prevention of Suicidal Behavior in At-risk Adults: a Quasi-experimental Ambispective Cohort Study
Background: Suicidal behavior represents a major public health problem worldwide. According to the World Health Organization (WHO), approximately 720.000 people die by suicide annually, and many more attempt it.
- Trial name
- NCT07655986
- Testing
- PPS; SUICIDE PREVENTION PROGRAM
- Where
- Spain
- Volunteers
- 198 people
- Sponsor
- University of Salamanca
Substance Abuse, Suicide
Functional Connectivity Alterations in Suicidal Patients Among Opioid Users
Suicide is the 10th leading cause of death for Americans of all ages and more people in the United States now die from suicide than die from car accidents.
- Conditions
- Substance Abuse, Suicide, Depression
- Trial name
- NCT05489042
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Suicide, Trauma
Integrated Suicide & Trauma Therapy for Suicide Risk
The investigators have developed a novel suicide intervention, Integrated Suicide and Trauma Therapy (ISTT). ISTT combines Brief-Skills for Safer Living (Brief-SfSL)-a promising method to enhance coping skills and reduce…
- Conditions
- Suicide, Trauma, Major Depressive Disorder
- Trial name
- ISTT (NCT05613972)
- Testing
- Integrated Suicide and Trauma Therapy
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Unity Health Toronto
Suicide
Online Referral and Intervention to Prevent Adolescent and Young Adult Suicide
ORIAS is a randomized controlled trial designed to study the efficacy of the ELIOS system in reducing suicidality in the AYA, reinforcing their motivation to seek help and making them access to care.
- Trial name
- ORIAS (NCT04642157)
- Testing
- ELIOS, other resources contacts
- Where
- France
- Volunteers
- 396 people
- Sponsor
- University Hospital, Lille