Clinical trials: Self-Injurious Behavior, open to volunteers
Depression, Suicide
Youth Depression and Suicide Research Network
The objective of this study is to build the Texas Youth Depression and Suicide Research Network to support the development of a Network Participant Registry and characterization of systems and interventions to examine statewide…
- Conditions
- Depression, Suicide, Suicidal Ideation, Suicide, Attempted
- Trial name
- YDSRN (NCT04572321)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- University of Texas Southwestern Medical Center
Problem Behavior, Aggression
Basic and Applied Research on Extinction Bursts
Although highly effective, treatments like FCT include extinction, which can have adverse side effects. The extinction burst, an increase in the frequency or intensity of destructive behavior at the start of treatment, is the…
- Conditions
- Problem Behavior, Aggression, Self Injury
- Trial name
- NCT05925101
- Testing
- Extinction-only condition, Rate-drop condition, Rate-hold condition
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Anhedonia, Depression and Suicide Ideation
Get ActivE Study for At-risk Youth
The study will adapt and deploy a digital Behavioral Activation app with mobile sensing, supported by health coaches, that encourages youth to engage in positive activities.
- Trial name
- GetActivE (NCT06829953)
- Testing
- GET ActivE, Treatment As Usual
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of Pittsburgh
Suicidal, Suicide, Attempted
Improving Coping to Reduce Suicide Risk Following ED Discharge
The researchers hope to learn whether an electronic safety plan (ESP) and a supportive text messaging program are feasible and acceptable to adult patients with recent suicidal thoughts or behavior after emergency department (ED)…
- Conditions
- Suicidal, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT06614946
- Testing
- Electronic Safety Plan (ESP), Text support
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Michigan
Depression, Psychiatric Diagnosis
Long-term Follow-up of Depressive Disorders in Psychiatric Care
The project investigates long-term prognosis and predictors of treatment outcomes for difficult-to-treat depression in patients in secondary psychiatric care.
- Conditions
- Depression, Psychiatric Diagnosis, Personality Disorders, Suicide, Attempted
- Trial name
- NCT07078227
- Testing
- No intervention is used.
- Where
- 2 sites in Sweden
- Volunteers
- 415 people
- Sponsor
- Region Skane
Suicidal Thoughts and Behaviors
From Court to the Community
Youth involved in the juvenile justice system evidence disproportionately high rates of suicidal thoughts and behavior (STB) and non-suicidal self-injury (NSSI) compared to adolescents in the general population.
- Trial name
- JJ-COPES (NCT06227169)
- Testing
- JJ-COPES Training
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Suicide
Self-hangIng Patient and Hyperbaric Oxygen Therapy _ SIPHON Study
During an attempted hanging, patients present severe neurological distress that can lead to major neuropsychiatric sequelae. These sequelae are notably due to significant cerebral edema related to hanging.
- Trial name
- SIPHON (NCT07461272)
- Testing
- OXYGENE MEDICINAL LIQUIDE AIR PRODUCTS MEDICAL
- Volunteers
- 50 people
- Sponsor
- University Hospital, Lille
Advanced Cancer, Demoralization
A Feasibility Study of a Digitally-enabled Psychological Intervention for Demoralization in Advanced Cancer Patients
Advanced cancer is a leading cause of death worldwide and in China. Cancer patients often face reduced independence and self-care abilities, which may lead to psychological disturbances such as helplessness, hopelessness, or…
- Conditions
- Advanced Cancer, Demoralization, Psychological Intervention
- Trial name
- NCT07872254
- Testing
- A digitally-enabled positive psychological intervention for demoralization in advanced cancer patients
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Transcranial Alternating Current Stimulation, Non-suicidal Self-injury
Intervention Effect of High-Definition Transcranial Alternating Current Stimulation (HD-tACS) on Non-suicidal Self-injury (NSSI)
To investigate the intervention effect of high-definition transcranial alternating current stimulation (HD-tACS) on patients with Non-suicidal Self-injury (NSSI) and its underlying neural mechanism by magnetic resonance imaging…
- Trial name
- NCT06127056
- Testing
- High-Definition Transcranial Alternating Current Stimulation (HD-tACS)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Depression, Suicidality
Assessing Improvements in Mood and Sleep Trial
This is a multi-site randomized control trial involving people age 55+ years who have current depression symptoms plus another suicide risk indicator (either current suicidal ideation or a past history of attempt).
- Conditions
- Depression, Suicidality, Sleep
- Trial name
- AIMS (NCT06639477)
- Testing
- Treatment As Usual, Active Condition, Active Comparator
- Where
- 3 sites in United States
- Volunteers
- 420 people
- Sponsor
- University of Pittsburgh
Suicide Attempt, Depression
Effects of a Multifaceted School-Based Intervention to Protect Mental Health and Prevent Suicidal Behaviour in Adolescents in Spain
What is this study about? This study aims to find out if a school-based program can help improve mental health and prevent suicidal thoughts and behaviors in teenagers in Spain.
- Conditions
- Suicide Attempt, Depression, Adolescent Mental Health, Self-Harm
- Trial name
- NCT06996054
- Testing
- Multifaceted School-Based Mental Health and Suicide Prevention Program
- Volunteers
- 2,280 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Leadership, Self-Harm
Implementing Evidence-Based Nursing: Leadership and Organizational Change for Implementation
This study aims to find out whether a leadership and organizational development program called the LOCI (Leadership and Organizational Change for Implementation) strategy can help nurses and their managers use the best available…
- Conditions
- Leadership, Self-Harm, Malnutrition Elderly
- Trial name
- LOCI-FIN-P (NCT07378696)
- Testing
- Leadership and organizational change for implementation
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Jaakko Varpula
Suicidal Ideation
(Cost)-Effectiveness of ABFT for Suicidal Youth.
Young adults who attempt to kill themselves is a common and serious mental health problem worldwide and certainly in Belgium and the Netherlands. Fatal suicide is the leading cause of death among young adults.
- Trial name
- REPAIR (NCT05965622)
- Testing
- Attachment Based Family Therapy (ABFT) + Treatment As Usual (TAU), Treatment As Usual (TAU)
- Where
- 13 sites in Belgium, Netherlands
- Volunteers
- 138 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Suicidal Ideation, Suicidal and Self-injurious Behavior
A Comparison of Two Brief Suicide Prevention Interventions Tailored for Youth on the Autism Spectrum
Rates of suicide have increased significantly over the past two decades, particularly among youth. Compared to the general population, autistic people are significantly more likely to think about suicide, attempt suicide, and die…
- Conditions
- Suicidal Ideation, Suicidal and Self-injurious Behavior, Suicide, Autism Spectrum Disorder
- Trial name
- NCT05398250
- Testing
- Safety Planning Intervention tailored for Autistic Individuals, Safety Planning Intervention Tailored for Autistic Individuals Plus Structured Follow-Up Contacts
- Where
- 5 sites in United States
- Volunteers
- 1,665 people
- Sponsor
- University of North Carolina, Chapel Hill
Nonsuicidal Self Injury, Emotion Regulation
Emotion Regulation Dysfunctions in NSSI Adolescents in Naturalistic Contexts
Nonsuicidal self-injury (NSSI) is defined as direct, deliberate bodily harm without suicidal intention. Recent studies indicate that prevalence rates are increasing worldwide, in particular under adolescents, indicating a growing…
- Trial name
- NCT05907421
- Testing
- Acceptance mindset
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Clinical High Risk for Psychosis (CHR), Suicidal Ideation
Developing a Recovery-Oriented Suicide Prevention Program for Young People at Clinical High Risk for Psychosis
Young people at clinical high risk for psychosis are more likely to experience suicide thoughts than the general population, but there are few suicide prevention programs designed specifically for them.
- Conditions
- Clinical High Risk for Psychosis (CHR), Suicidal Ideation, Psychosis, Suicidal Behavior
- Trial name
- NCT07756567
- Testing
- Suicide Prevention Intervention, Standard Care (in control arm)
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- University of California, San Diego
Suicide, Suicide Attempt
Efficacy of a Smartphone Suicide Prevention App
It is an interventional research, single-blind, randomized, controlled, multicenter, which involves only minimal risks and constraints.
- Trial name
- PreventS (NCT07160465)
- Testing
- emma application
- Where
- France
- Volunteers
- 632 people
- Sponsor
- University Hospital, Montpellier
Suicide
e-Connect: A Service System Intervention for Justice Youth at Risk for Suicide
The investigators propose to create e-Connect, a new service delivery model that will enable real time identification and targeted, county-specific referral and linkage of participants with suicidal behavior (SB) and related…
- Trial name
- NCT03586895
- Testing
- e-Connect
- Where
- United States
- Volunteers
- 12,838 people, healthy volunteers welcome
- Sponsor
- Columbia University
Suicide Prevention
Suicide Prevention After Community Care Discharge
The study is of high importance to Veterans' health because it will study a suicide prevention intervention in a Veteran population that is at high risk of suicide but has not been a specific focus of the Veteran Affairs' (VA's)…
- Trial name
- NCT06596044
- Testing
- VA BIC, Standard Care
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- VA Office of Research and Development
Nonsuicidal Self-injury, Depression
Developing a Digital Intervention for Adolescent Nonsuicidal Self-injury
This is a feasibility trial of a digital mental health intervention aimed at adolescents (ages 14-18) with nonsuicidal self-injury and who are not currently engaged in mental health treatment.
- Conditions
- Nonsuicidal Self-injury, Depression, Anxiety
- Trial name
- NCT07224165
- Testing
- App-based digital mental health intervention for adolescent NSSI, App-based delivery of healthy living psychoeducational materials
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University