Clinical trials: Self-Injurious Behavior, open to volunteers
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Psychological Distress, Suicidal Ideation
Flourish in Schools Pilot Study
This study will test Flourish, a digital suicide prevention intervention for cyberbullied youth, within schools. Specifically, the study aims to: 1.
- Trial name
- NCT07506525
- Testing
- Flourish
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Candice Biernesser
Sleep Problems, Suicidal Ideation
Sleep Treatment for Teens (RCT Phase)
The purpose of this research study is to compare (vs. treatment as usual) a brief (6-session), empirically supported, and highly disseminable version of digital (i.e., smartphone or web-based) cognitive behavioral therapy for…
- Conditions
- Sleep Problems, Suicidal Ideation, Suicidal Behavior
- Trial name
- NCT07303959
- Testing
- Sleepio, Treatment as Usual (TAU)
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
Suicidal Ideation, Suicide Attempt
Advancing Student Suicide Interventions With Scalable Technologies
Mobile-based applications, such as JasprHealth, can deliver evidence-based skills intended to reduce imminent suicide risk (e.g., reducing means access), improve emotional states (e.g., via distraction and coaching to act…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self-Harm
- Trial name
- ASSIST (NCT07211373)
- Testing
- Jaspr, Behavioral support
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Massachusetts, Amherst
Sleep Disturbance, Sleep
Sleep and Circadian Interventions for College Students at High Risk of Suicide
The purpose of this study is to examine the extent to which delivering sleep and circadian focused interventions in addition to evidenced based psychiatric care for depression and suicide risk may contribute to decreasing suicide…
- Conditions
- Sleep Disturbance, Sleep, Depression, Suicide
- Trial name
- REST-UP (NCT07346014)
- Testing
- Sleep Feedback + Psychoeducation, Transdiagnostic Sleep and Circadian Intervention + Bright Light (TSC+), Triple Chronotherapy (TCT+)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Pittsburgh
Suicide Prevention, Suicidal Ideation
Co-creation of Tools for Children and Adolescents with Suicidal Thoughts And/or Behaviour
Evidence shows that there are very few evidence-based tools or interventions specifically targeting suicidality in children and adolescents.
- Conditions
- Suicide Prevention, Suicidal Ideation, Suicidal Behaviors
- Trial name
- Co-crea K&J (NCT06776328)
- Testing
- Tools
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Ghent
Suicidal Ideation, Suicidal Behavior
Intravenous Ketamine for Acute Suicidal Crisis and Psychiatric Hospital Length of Stay
This randomized, double-blind, active placebo-controlled superiority trial will evaluate whether intravenous esketamine reduces time to psychiatric hospital discharge in adults hospitalized because of acute suicide risk.
- Trial name
- NCT07888933
- Testing
- Esketamine, Midazolam (Intravenous)
- Where
- Brazil
- Volunteers
- 106 people
- Sponsor
- University of Sao Paulo
Major Depressive Disorder
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
The study will consist of a 24-week-long trial examining outcomes in patients with Major Depressive Disorder and suicidal ideation who will receive intravenous (IV) ketamine and intranasal (IN) esketamine, compared to a large…
- Trial name
- NCT05450432
- Testing
- Ketamine, Esketamine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Nonsuicidal Self Injury, Emotion Regulation
Emotion Regulation Dysfunctions in NSSI Adolescents in Naturalistic Contexts
Nonsuicidal self-injury (NSSI) is defined as direct, deliberate bodily harm without suicidal intention. Recent studies indicate that prevalence rates are increasing worldwide, in particular under adolescents, indicating a growing…
- Trial name
- NCT05907421
- Testing
- Acceptance mindset
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Mood Disorders, Suicide, Attempted
Youth Suicide Risk Factors, Reduction of Suicide Risk Factor in Youth People
The YOU-SURF project is at the forefront of youth suicide prevention, with the goal of integrating multimodal clinical and neurobiological data to comprehensively identify risk factors and the most effective intervention…
- Conditions
- Mood Disorders, Suicide, Attempted, Suicidal Ideation, Suicide Prevention
- Trial name
- YOU-SURF (NCT07188506)
- Testing
- Clinical and blood parameters, Illumina Infinium Global Screening Array 4.0 (GSA 4.0), dTMS treatment
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Suicide Prevention
Suicide Prevention for Substance Using Youth Experiencing Homelessness
Suicide is the leading cause of death among YEH and most youth do not access services that may be available to them. Therefore, this study seeks to address this gap in the research literature with the goal to identify an…
- Trial name
- NCT05994612
- Testing
- Cognitive Therapy for Suicide Prevention, Services as Usual
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Suicidal Ideation, Major Depressive Disorder (MDD)
Understanding and Treating Suicidal Ideation With Ketamine
The goal of this clinical trial is to treat active suicidal ideation in individuals with Major Depressive Disorder (MDD) using ketamine and to understand suicidal ideation by examining biological mechanisms using magnetic…
- Trial name
- NCT06891300
- Testing
- ketamine hydrochloride
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- The Royal's Institute of Mental Health Research
Suicide
Online Referral and Intervention to Prevent Adolescent and Young Adult Suicide
ORIAS is a randomized controlled trial designed to study the efficacy of the ELIOS system in reducing suicidality in the AYA, reinforcing their motivation to seek help and making them access to care.
- Trial name
- ORIAS (NCT04642157)
- Testing
- ELIOS, other resources contacts
- Where
- France
- Volunteers
- 396 people
- Sponsor
- University Hospital, Lille
Suicide, Co-design
Development of a Digital Acceptance and Commitment Therapy Intervention for Suicide Prevention in Adults Through Co-design
Suicide is a major public health concern and there is a need for accessible and scalable interventions to support individuals experiencing suicidal thoughts.
- Conditions
- Suicide, Co-design, Suicide Prevention
- Trial name
- NCT07733596
- Testing
- Digital ACT Intervention
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Hong Kong Polytechnic University
Suicidal Thoughts and Behaviors
Development of PRECISE: A Data Driven Personalized Suicide Prevention Intervention
Individuals at high-risk of suicide vary substantially from one another. Over time, risk factors for suicide may change within the same individual.
- Trial name
- NCT06809348
- Testing
- PRECISE
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Diego
Suicide, Secure Firearm Storage
Reducing Firearm Suicide Among Veterans: Evaluating the Effectiveness of Peer-Delivered Lethal Means Counseling
Suicide prevention is a top priority for the Department of Veterans Affairs (VA), with a major emphasis on developing innovative and effective ways to prevent firearm suicide.
- Trial name
- NCT07033884
- Testing
- Peer Engagement and Exploration of Responsibility and Safety, Active Control
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Sleep Disorder, Mental Health Issue
Improving Sleep in a Psychiatric Hospital
The purpose of this study is to examine effects of sleep promotion versus treatment as usual (TAU) on subjective, self-reported sleep while in inpatient psychiatric treatment, to examine effects of sleep promotion vs.
- Trial name
- NCT07010718
- Testing
- Scented Oil, Ear Plugs, Eye Mask
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center, Houston
Suicidal Ideation, Suicide Attempt
A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior
This study aims to evaluate the acceptability, safety, and efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors (STB) among…
- Trial name
- NCT06686901
- Testing
- Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S), Smartphone-delivered inactive Therapeutic Evaluative Conditioning
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Suicidal Behavior, Adolescent
Suicidal Behavior in Adolescents and Executive Functions
Suicide is a major public health concern, particularly among young people. In France, around 400 adolescents die by suicide every year, and suicide attempts are most frequent during adolescence.
- Trial name
- SAFE (NCT07422493)
- Testing
- Neuropsychological Tests and Psychiatric Tests
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Suicide
Suicide Risk Interventions
The suicide rate among active duty service members and Veterans increased substantially following the onset of post-9/11 conflicts in Iraq and Afghanistan.
- Trial name
- NCT05931289
- Testing
- Enhanced Crisis Response Planning (ECRP), Brief Cognitive Behavioral Therapy for Suicide Prevention (BCBT)
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- VA Office of Research and Development