Clinical trials: Self-sampling
Cancer of the Uterine Cervix
Feasibility and Acceptability of Offering Self-sampling to Non-attendees in Primary Care
The purpose of this study is to determine whether human-papillomavirus (HPV) self-sampling can be used as a primary screening test for unscreened women.
- Trial name
- DEPIST (NCT02698423)
- Testing
- Cobas HPV DNA Test, Papanicolau test
- Volunteers
- 667 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
HIV, STI
Feasibility and Impact of Online HIV/STI Screening Addressed to PrEP Users in Spain
Non-blinded randomized controlled non-inferiority trial to evaluate the feasibility, acceptability and impact of an innovative internet-accessed HIV and STIs screening intervention (TÉSTATE PrEP) addressed to gays, bisexuals and…
- Trial name
- TESTATE_PrEP (NCT05752643)
- Testing
- Online follow up
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol
Cervical Cancer, Cervical Dysplasia
Self-sampling for Non-attenders to Cervical Cancer Screening
The trial will evaluate whether self-sampling and human papillomavirus (HPV) testing may increase cervical cancer screening attendance among under-screened women in Czech Republic.
- Conditions
- Cervical Cancer, Cervical Dysplasia, Human Papillomavirus Infection
- Trial name
- KOPRETINA (NCT04226313)
- Testing
- Self-sampling by Evalyn Brush, Self sampling by Evalyn Brush home or in GP´s clinic
- Where
- Czechia
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- The Institute of Molecular and Translational Medicine, Czech Republic
Cervical Cancer
Cervical Cancer Prevention for Black Adults
The goal of this study is to develop and pilot test an intervention, entitled Health is Wealth: A Cervical Health Program, designed to promote screening and reduce perceived barriers to Cervical Cancer (CC) screening.
- Trial name
- NCT04927494
- Testing
- Health is Wealth: A Cervical Health Program
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Adebola Adegboyega
HIV, Hepatitis B
Pan-Viral Screening and Linkage to Care Among GBMSM and Trans Women in Spain
The World Health Organization (WHO) aims to eliminate viral hepatitis as a public health threat by 2030, with major reductions in hepatitis B and C incidence and mortality.
- Conditions
- HIV, Hepatitis B, Hepatitis C
- Trial name
- PAN-TESTATE (NCT07085715)
- Testing
- Online self-sampling testing strategy to enhance pan-viral testing (HBV, HCV, HIV)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol
Cervical Cancer, HPV Infection
ELEVATE Acceptability Study
This study includes a community-based, two-arm prospective acceptability study, whereby arm 1 consists of an educational session on sexual health and cervical cancer (screening) and a follow-up assessment after 3 months.
- Conditions
- Cervical Cancer, HPV Infection, Acceptability of Health Care
- Trial name
- ELEVATE AS (NCT06136702)
- Testing
- Educational session, Self-sampling, Follow-up assessment
- Where
- 4 sites in Belgium, Brazil and 2 more
- Volunteers
- 1,048 people, healthy volunteers welcome
- Sponsor
- University Ghent
Cervical Cancer Screening
Breast Cancer-Related Approach for Increasing Cervical Cancer Screening
The primary objective of this clinical trial is to assess cervical cancer screening participation among under-screened women invited through organized breast cancer screening programs in Switzerland.
- Trial name
- BRAICS (NCT07171658)
- Testing
- Sensitization to Cervical Cancer (CC) screening, Home-based HPV self-sampling
- Where
- Switzerland
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Jessica Di Vincenzo Sormani
Cervical Cancer
Acceptability of HPV-self Sampling
This trial aimed at evaluating the acceptability of HPV self-sampling among french women eligible for cervical cancer screening (25 - 65 years old) in the region of Occitanie, in the south of France.
- Trial name
- NCT03137563
- Testing
- questionnaire
- Where
- France
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Uterine Cervical Neoplasm
HPV Self-sampling for Underscreened Latinas
The goal of this study is to learn if women of Hispanic/Latina ethnicity are willing to self-collect a cervico-vaginal sample for HPV testing.
- Trial name
- NCT06439706
- Testing
- HPV Self-Sampling, Group Education
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Cancer Cervix
Carrying Out of Focus Group to Improve Cervical Screening Proposal by Vaginal Self-sampling (APACHE-4/FG).
Despite the existence of an effective screening test (pap smear), cervical cancer is, every year in France, the cause of more than 3,000 new cases and 1,100 deaths.
- Trial name
- APACHE-4/FG (NCT03420157)
- Testing
- Focus Group
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Malignant Tumor of Cervix, Cervical Intraepithelial Neoplasia
Participation in Screening for Cervical Cancer: Interest of a Self-sampling Device Provided by the General Practitioner
This study evaluates the benefit in women aged from 30 to 65 years, who do not participate to the French opportunistic cervical cancer screening program, of an organized screening with the proposition by the family physician of a…
- Trial name
- PaCUDAHL-Gé (NCT02749110)
- Testing
- Vaginal self-sampling brush
- Where
- France
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Cervical Cancer
Using CHWs and HPV Home Tests to Increase Cervical Cancer Screening in Minority Populations
Caribbean immigrants (both Hispanics and Blacks from Haiti) are less likely to be screened for cervical cancer than the general population.
- Trial name
- SUCCESS (NCT02121548)
- Testing
- CHW Outreach and HPV Self-sampling, CHW Outreach
- Where
- United States
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- University of Miami
HIV Infection, Syphilis
Strengthening, Guidance, Health, Empowerment
The goal of this interventional study is to describe the care pathway following the use of an innovative home self-sampling method for the screening of six sexually transmitted infections (STIs) among sex workers met during…
- Conditions
- HIV Infection, Syphilis, Gonorrhea Infection, Chlamydia Infection
- Trial name
- ROSE (NCT07788599)
- Testing
- Self-sampling for six sexually transmitted infections
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Cervical Cancer, Cervical Cancer Screening
Accelerating Adoption of Patient-centered Cervical Cancer Screening and Treatment Linkage in Kenya
This study aims to test the use of a multi-component care strategy (DADA LINK) designed to improve cervical cancer screening and linkage to treatment.
- Conditions
- Cervical Cancer, Cervical Cancer Screening, HPV DNA
- Trial name
- DADA-LINK (NCT07050745)
- Testing
- DADA LINK
- Where
- Kenya
- Volunteers
- 1,980 people, healthy volunteers welcome
- Sponsor
- Kenyatta National Hospital
Healthy Adult Participants, Gynecological Disease
Methylation Analyses for Gynaecological Research Through Home-based Self-sampling
The goal of the MARGOT study is to collect self-samples, such as first-void urine and vaginal samples, from people without cancer and compare them with samples from people with gynecological (pre-)cancers collected in other…
- Trial name
- MARGOT (NCT07902388)
- Testing
- Colli-Pee 20 mL device with UCM, Evalyn Brush
- Where
- Belgium
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Anxiety Depression, Emotion Regulation
Improving Emotion Regulation Flexibility: Testing the Efficacy of an Emotion Regulation Program in College Students
The main objective of this RCT is to test the efficacy of an emotion regulation group program (i.e., ART program) in college students, compared to an active control group (i.e., relaxation program).
- Trial name
- REFLEX (NCT05390034)
- Testing
- ART, Relaxation
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Periodontitis, Diagnostic Self Evaluation
Diagnostic Accuracy of Matrix Metalloproteinase-8 Test for the Discrimination of Periodontal Health and Disease
The application of point-of-care test with oral fluid-based biomarkers assisting in early-detection of gum disease is highly needed.
- Trial name
- NCT05099731
- Where
- China
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Human Papilloma Virus Infection
Standard Operating Procedures for Anti-HPV (Human Papillomavirus) Antibody Detection in First-void Urine (AB-SOP Study)
The aim of the study is to develop robust analytical protocols for first-void urine sample preparation and antibody assays to monitor natural and/or vaccine induced immunity against HPV (Human Papillomavirus).
- Trial name
- AB-SOP (NCT02714114)
- Testing
- First-void urine collection, Blood draw
- Where
- Belgium
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
HPV, HPV Associated Cancers
Emergency Department-based Cervical Cancer Screening Through Self-sampling
This project will compare the uptake of cervical cancer screening through ED HPV sampling among patients presenting to the ED.
- Conditions
- HPV, HPV Associated Cancers, HPV Cancers, Cervical Cancer Screening
- Trial name
- NCT07345897
- Testing
- Cervical Cancer Screening
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Human Papilloma Virus Infection
Developing Methods to Investigate Additional Opportunities of HPV Vaccination by Using First-void Urine Samples
The main objective of this study is to develop protocols using FV urine that investigate in vitro whether infectious virions can be neutralized by HPV vaccination.
- Trial name
- HPV-VACPLUS (NCT04391647)
- Testing
- First-void urine collection, Blood draw
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen