Clinical trials: Seniors
Nutrition, Healthy, Metabolic Syndrome
Effect of a New Optimized Plant Ingredient on the Plant Protein of Seniors at Cardio-metabolic Risk
The aim of the study is to compare the use of amino acids in whole-body protein metabolism in elderly consumers at risk of metabolic syndrome, after ingestion of 2 foods differing only in the nature of their proteins (optimized…
- Trial name
- P-Probs (NCT06933589)
- Testing
- Test meal with plant protein, Test meal with milk protein
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Cognitive Function
Seniors Health and Activity Research Program-Pilot
The purpose of this pilot study is to develop and conduct well-designed trial to assess whether a multi-factorial intervention involving physical activity and cognitive training reduces the risk of significant cognitive decline…
- Trial name
- SHARP-P (NCT00688155)
- Testing
- Physical Activity Training, Cognitive Training, Healthy Aging Education
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Adverse Drug Events, Adverse Drug Reactions
YouScript IMPACT Registry
This multicenter observational study aims to investigate the benefits of providing pharmacogenetic testing with the YouScript Personalized Prescribing System which includes a clinical decision support tool and individualized…
- Conditions
- Adverse Drug Events, Adverse Drug Reactions, Drug Interaction Potentiation, Drug Metabolism, Poor, CYP2D6-RELATED
- Trial name
- IMPACT (NCT02191358)
- Where
- 7 sites in United States
- Volunteers
- 800 people
- Sponsor
- Genelex Corporation
Sedentary Behavior, Aging
Promoting Fall Prevention Workshops
Physical Activity (PA) is recognized as the most effective method to prevent falls in the elderly. Yet despite there being a consensus now that Physical Activity (PA) is effective in practice, there remain many obstacles to…
- Trial name
- NCT04134585
- Testing
- semi-structured interviews
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Breast Neoplasms, Medication Adherence
A Novel E-Health Approach in Optimizing Treatment for Seniors (OPTIMUM Study)
Background: In women with hormone receptor positive (HR+) breast cancer, adjuvant endocrine therapy (AET) is associated with a significant survival advantage.
- Trial name
- NCT02876848
- Testing
- OPTIMUM e-health tool
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Fall, Fall Injury
Testing the SNOWDROP Intervention: Using a Clinical Decision Support System and Patient Portal for Falls Prevention Among Older Patients in Primary Care
Falls are a leading cause of injuries among older patients. Medication use is a major risk factor for falls. Because we lack tools to assess individualized risks, general practitioners (GPs) struggle with fall-related medication…
- Conditions
- Fall, Fall Injury, Fall Patients, Accidental Fall
- Trial name
- SNOWDROP (NCT05611008)
- Testing
- CDSS, Patient Portal
- Where
- Netherlands
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Amsterdam
Well Aging
Art'Health: Effects of Artistic and Participative Workshops at the MAMAC of Nice on the Health of Seniors
Study with two arms, one of which receives an intervention in the form of participative artistic workshops at the MAMAC and the other was assigned as the control group.
- Trial name
- Art'Health (NCT04570813)
- Testing
- Artistic activies
- Where
- France
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Hypertension, Aging
ACE Inhibitors Combined With Exercise for Seniors - Pilot Study
The purpose of this study is to compare, when combined with chronic exercise, the effects of perindopril, losartan, and hydrochlorothiazide.
- Trial name
- ACES-P (NCT01891513)
- Testing
- Exercise, ACE inhibitor + exercise, Thiazide diuretic + exercise
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Florida
Healthy Aging, Aging
An Evaluation of Folic Acid to Improve Endothelial Sensitivity to Shear Stress in Seniors
The purpose of this study is to evaluate if folic acid improves endothelial sensitivity to shear stress in post-menopausal women.
- Conditions
- Healthy Aging, Aging, Menopause
- Trial name
- NCT04016090
- Testing
- Folic Acid
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Montreal Heart Institute
Breast Cancer, Colon Cancer
Partnership for Healthy Seniors
The Centers for Medicare and Medicaid Services (CMS) has awarded cooperative agreements to 6 sites from across the country (Salt Lake City, UT, Molokai, HI, Houston, TX, Newark, NJ, Detroit, MI, and Baltimore City) to participate…
- Conditions
- Breast Cancer, Colon Cancer, Rectum Cancer, Cervix Cancer
- Trial name
- NCT00379743
- Testing
- Health coordinator (or patient navigator), Educational materials only
- Where
- United States
- Volunteers
- 2,593 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
The Focus is to Assess 25-hydroxyvitamin D Levels and Well-being
Vitamin D Fortified Cheese and Well-being in the Institutionalized Elderly
The investigators hypotheses is that the consumption of the investigators vitamin D fortified cheese will result in an increase in serum 25-hydroxy vitamin D levels in older institutionalized adults.
- Trial name
- NCT01555424
- Testing
- High dose, Reference dose
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Macular Degeneration
Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration (AMD)
This study is a phase III, double-masked, randomized, study of the efficacy and safety of VEGF Trap-Eye in patients with neovascular age-related macular degeneration.
- Trial name
- VIEW 2 (NCT00637377)
- Testing
- Ranibizumab, Aflibercept Injection (EYLEA, VEGF Trap-Eye, BAY86-5321)
- Where
- 189 sites in Argentina, Australia and 24 more
- Volunteers
- 1,240 people
- Sponsor
- Bayer
Psychological Resilience, Career Decision Making
Effect of a Nurse-Led Transition Program on Resilience and Career Decisions in Senior Students
The transition to higher education is a critical stage that affects young people's academic, emotional, and professional development.
- Trial name
- NCT07823881
- Testing
- Nurse-Led On-Campus Experiential Transition Program
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Muscle Weakness
Promoting Seniors' Health With Home Care Aides
This study aims to test whether a safe physical activity program with a built-in motivational enhancement component, performed in a seated position, preserves the function and well-being of older home care clients.
- Trial name
- NCT03301116
- Testing
- Healthy Moves for Aging Well (Healthy Moves), Active Mind for Aging Well (Active Mind)
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- University of Illinois at Chicago
Healthy
Activating Seniors to Improve Chronic Disease Care
Chronic diseases are the primary cause of morbidity and mortality for older Americans. Active patient participation in treatment decision-making has the potential to significantly improve outcomes in chronic disease care, but…
- Trial name
- NCT00651495
- Testing
- Patient decision aids for chronic conditions
- Where
- 2 sites in United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Depressive Symptom, Cognitive Functions
Cognicise Training for Seniors for Healthy Aging
The goal of this clinical trial is to assess the impact of two 8-week motor-cognitive exercise programs - Cognicise and yoga - on psychological, respiratory, cardiovascular, postural, and biochemical health in elderly women.
- Conditions
- Depressive Symptom, Cognitive Functions, Quality of Life, Physical Fitness
- Trial name
- NCT07098533
- Testing
- Cognicise Training, Yoga Training
- Where
- Poland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Community-dwelling Seniors, History of a Fall in the Previous 12 Months
Zurich Disability Prevention Trial
This project was designed to optimizing vitamin D status in prefrail seniors age 70+ living at home and prevent their functional decline. We test 3 arms of monthly vitamin D supplementation.
- Trial name
- ZDPT (NCT01017354)
- Testing
- Hidroferol® (ES), ViDe3 (CH)
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University of Zurich
ESRD, Social Behavior
SOCIABLE Seniors Optimizing Community Integration to Advance Better Living With ESRD
This research is being done to find out the best ways to help people with end stage kidney disease take care of their daily lives and improve their social functioning.
- Conditions
- ESRD, Social Behavior, Physical Disability
- Trial name
- SOCIABLE (NCT03055273)
- Testing
- SOCIABLE
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Johns Hopkins University
Sedentary Lifestyle in Patients Over 70
Effect of PEP'C-R on Endurance Parameters and Maximal Cardio-respiratory Function Among Sedentary Older Seniors Over 70
The primary purpose of the protocol is to determine the effects of a new program of PEP'C "PEP'C with constant load and intermittent recovery" (PEP'C-R) on endurance parameters of older seniors.
- Trial name
- PEP'C-R (NCT02263573)
- Testing
- PEP'C-R, Control group usual activities
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Microkinesitherapy
Effectiveness of Microkinesitherapy in Seniors
Many specialists stress that the aging process is individual, its course, severity and occurrence of disease are not the same for all seniors.
- Trial name
- NCT05494879
- Testing
- microkinesitherapy treatment
- Where
- Poland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology