Clinical trials: Sensation Disorders
Hearing Loss, Presbycusis
Variability In Hearing Aid Outcomes In Older Adults
The goal of this project is to find out if the way a hearing aid processes a sound signal should be determined in part by an individual's cognitive characteristics.
- Trial name
- NCT02448706
- Testing
- Hearing Aid Fitting A, Hearing Aid Fitting B
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Northwestern University
Tinnitus
rTMS To The Dorsolateral Prefrontal Cortex For Patients With Subjective Idiopathic Tinnitus. A Pilot Study
The neurological basis of tinnitus is uncertain when there is no evidence of damage to the peripheral auditory system. However, neuroimaging studies of tinnitus patients show hyperactivity in several cortical regions, especially…
- Trial name
- NCT00886938
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), pilot study
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Washington University School of Medicine
Acute Pain, Hyperalgesia
IV Acetaminophen as an Adjunct Analgesic in Cardiac Surgery
Patients undergoing cardiac surgery experience significant postoperative pain, which may impact postoperative outcomes. The aim of this single center, double-blind, randomized, placebo controlled trial is to determine if…
- Trial name
- CarDolMev (NCT01544062)
- Testing
- IV acetaminophen
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Washington
Hearing Loss
Cochlear Implantation in Adults With Asymmetric Hearing Loss Clinical Trial
This longitudinal study evaluates the possible benefit of cochlear implantation in the poor ear of adults with asymmetric hearing loss who continue to use a hearing aid in the better hearing ear.
- Trial name
- NCT03052920
- Testing
- Cochlear implant
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Hearing Loss
Benefits of Assistive Listening Device for Speech Intelligibility
Speech intelligibility in noise will be evaluated in adults with moderate to moderate-severe sensorineural hearing loss, using an assistive listening device and hearing aid, and compared to speech intelligibility in noise using…
- Trial name
- NCT05072470
- Testing
- Roger microphone, Phonak Audeo hearing aid
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sonova AG
Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis), Central Retinal Vein Occlusion With Macular Edema
Cool vs Room-temperature Artificial Tears
Background and Objective: To evaluate the efficacy of cooled versus room temperature artificial tears in reducing post intravitreal injection (IVI) ocular discomfort.
- Conditions
- Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis), Central Retinal Vein Occlusion With Macular Edema, Exudative Age-Related Macular Degeneration, Unspecified Eye, Cystoid Macular Edema
- Trial name
- NCT05832996
- Testing
- Refresh Plus Preservative-free Lubricant Eye Drops
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Hearing Loss
Safety and Feasibility of tDCS to Enhance Auditory Rehabilitation in Cochlear Implant Recipients
This study aims to evaluate the safety and feasibility of transcranial direct current stimulation (tDCS) in combination with home-based auditory training therapy in cochlear implant (CI) patients.
- Trial name
- NCT04908631
- Testing
- Transcranial Direct Stimulation, Auditory Training Program
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Duke University
Hearing Loss, Noise-Induced
Noise-Induced Hearing Loss-Acute Exposure Treatment
The purpose of this study is to assess the safety and efficacy of zonisamide for the treatment of noise-induced hearing loss in adults.
- Trial name
- PINIHL-AET (NCT04768569)
- Testing
- Zonisamide 100Mg Cap
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Tinnitus, Subjective
Action of Intra-auricular Topical Lidocaine on Tinnitus
The main objective of this clinical trial placebo controled is to evaluate the action of intraauricular topical lidocaine on tinnitus.
- Trial name
- NCT05711641
- Testing
- Lidocaine 10 MG/ML, Distilled water
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo General Hospital
Sensorineural Hearing Loss, Noise Induced Hearing Loss
FX-322 in Adults With Stable Sensorineural Hearing Loss
This is a phase 2a single and repeat dose exploratory efficacy study of intratympanic FX-322 compared to placebo in healthy male and female adults with stable sensorineural hearing loss.
- Conditions
- Sensorineural Hearing Loss, Noise Induced Hearing Loss, Sudden Sensorineural Hearing Loss
- Trial name
- NCT04120116
- Testing
- FX-322 (One Dose), FX-322 (Two Doses), FX-322 (Four Doses)
- Where
- 16 sites in United States
- Volunteers
- 95 people
- Sponsor
- Frequency Therapeutics
Hearing Loss, Sensorineural
Remote Microphone Candidacy Study
Despite improvements in digital hearing aid technology, many hearing aid users continue to report difficulty understanding speech in challenging listening environments.
- Trial name
- NCT03897634
- Testing
- Remote Microphone
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Hearing Loss
Evaluation of Open-canal Behind-the-Ear Hearing Aids and Traditional In-the-ear Hearing Aids.
This study is being conducted to evaluate the benefits of in-the-ear vs. open-fit behind-the-ear hearing aids. We want to learn more about which patients prefer each type, so we can make better choices about which type of hearing…
- Trial name
- NCT00727909
- Testing
- Hearing Aid Treatments
- Where
- 3 sites in United States
- Volunteers
- 290 people
- Sponsor
- US Department of Veterans Affairs
Bradycardia
INGEVITY+ Active Fixation Pace/Sense Lead Clinical Study
The objective of this study is it to confirm the safety and effectiveness of the INGEVITY+ Active Fixation Pace/Sense Lead.
- Trial name
- NCT04346537
- Testing
- INGEVITY+™ Pace/Sense Lead
- Where
- 13 sites in United States
- Volunteers
- 109 people
- Sponsor
- Boston Scientific Corporation
Macular Edema (ME)
To Assess the Efficacy and Safety of Intravitreal Ranibizumab in People With Vision Loss Due to Macular Edema
To evaluate the efficacy and safety of 0.5 mg Ranibizumab intravitreal injections in adult patients with visual impairment due to macular edema (ME).
- Trial name
- NCT01846299
- Testing
- Ranibizumab
- Where
- 61 sites in Australia, Belgium and 17 more
- Volunteers
- 181 people
- Sponsor
- Novartis Pharmaceuticals
Visual Impairment, Amblyopia Suspect
DigiVis: Self-testing Vision App for Telephone Consultations
This trial aims to assess the accuracy and test-retest variability of a new digital app which enables community visual acuity testing without requirement of an trained examiner.
- Trial name
- NCT04482387
- Testing
- DigiVis visual acuity app
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Hearing Loss
Safety and Effectiveness of the MED-EL Electric-Acoustic System
The purpose of this investigation is to demonstrate the safety and effectiveness of the MED-EL Electric-Acoustic System (EAS), a medical device that combines the use of a cochlear implant with an external electric-acoustic…
- Trial name
- EAS (NCT00747435)
- Testing
- Electric Acoustic System
- Where
- 14 sites in United States
- Volunteers
- 73 people
- Sponsor
- Med-El Corporation
Distorted; Balance, Sensation Disorders
A Wearable "Balance Booster" - Stepping Closer to the Market
The overall goal of this project is to continue development and commercialization of a Wearable Sensory Prosthesis termed Walkasins.
- Conditions
- Distorted; Balance, Sensation Disorders, Peripheral Neuropathy, Neuropathy
- Trial name
- NCT02115633
- Testing
- Walkasins ON, Walkasins OFF
- Volunteers
- 31 people
- Sponsor
- RxFunction Inc.
Tinnitus
Internet-based Cognitive Behavioural Therapy for Spanish Tinnitus Sufferers
Nearly 50 million people in the U.S. experience tinnitus, of which about 20 million people have burdensome chronic tinnitus. Tinnitus can be very debilitating as many aspects of daily life can be affected, such as sleep, mood…
- Trial name
- ICBT (NCT04335929)
- Testing
- Internet-based Cognitive Behavior Therapy
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Lamar University
Hearing Loss
Assessment of Novel Sound Changing Principles in Hearing Instruments to Determine Their Application - 2020_09
Participants will perform two different listening tasks: (1) listening to, and repeating back, sentence lists presented in noise, and (2) Subjective rating of effort \& performance following each condition.
- Trial name
- NCT04578457
- Testing
- Hearing Aid without NR enabled, Hearing Aid with NR(1), Hearing Aid with NR(2)
- Where
- Switzerland
- Volunteers
- 19 people
- Sponsor
- Sonova AG
Amblyopia, Ocular Motility Disorders
A New Approach to Vision Therapy Based on Naturalistic 3-D Computer Gaming
The research team will execute two concurrent studies within a common framework. The first will compare iCare to standard of care occlusion therapy (patching) for amblyopia in patients ages 4 to 18 (inclusive).
- Trial name
- ICARE (NCT03066063)
- Testing
- iCare, Amblyopia standard of Care, CI standard of Care
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Barron Associates, Inc.