Clinical trials: Sensitive Dentin, open to volunteers
Dentin Sensitivity
A Study to Assess the Efficacy of a Calcium Sodium Phosphosilicate Toothpaste for the Relief of Dentine Hypersensitivity
The aim of this study is to demonstrate the clinical efficacy of the Test Toothpaste containing Calcium Sodium Phosphosilicate (CSPS) in reducing Dentin Hypersensitivity (DH) to an evaporative (air) stimulus, compared to a sodium…
- Trial name
- NCT07894796
- Testing
- Test Toothpaste, Regular Fluoride Toothpaste
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Hypersensitivity
Clinical Effectiveness of Episodic Use of Bioactive Silica Based Versus in Management of Dentin Hypersensitivity (A 6m Randomized Clinical Trial)
The aim of the study to compare the clinical effectiveness of Episodic use of Bioactive Silica Based versus continuous use of fluoride based desensitizing toothpastes in management of dentin hypersensitivity (DH) of adult…
- Trial name
- NCT07120139
- Testing
- episodic use of the desensitizing toothpaste, continuous use of the conventional desensitizing toothpaste
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rawda Hesham Abd ElAziz
Tooth Sensitivity
The Effect of Bleaching Application Mode on Bleaching-induced Tooth Sensitivity.
The aim of this study is to evaluate the effect of single versus multiple application protocols for in-office dental bleaching using two different bleaching gels (Pola Office Plus, SDI, 37.5% HP and Opalescence Boost, Ultradent…
- Trial name
- NCT07173296
- Testing
- Opalescence XTra Boost 40% HP, Pola Office Plus 37.5% HP
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dentin Hypersensitivity
Evaluation of the Combined Effect of Bioactive Toothpastes, Desensitizing Agents and Er-YAG Laser on Dentin Hypersensitivity: an In-Vivo Study
Here's the revised version with the corrected treatment and follow-up session schedule: --- The aim of this clinical trial is to evaluate the effectiveness of bioactive toothpastes, desensitizing agents, and Er-YAG laser…
- Trial name
- NCT06854068
- Testing
- laser treatment, application of desensitizing agent
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ege University
Dentin Caries
Evaluation of the Effect of Flowable Composites on Postoperative Sensitivity in Class I Restorations.
The aim of this study is to evaluate the effect of flowable conventional and bulk-fill composites on postoperative sensitivity in class I cavities over long-term follow-up.
- Trial name
- NCT07343050
- Testing
- Dental restorations
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Bleaching; Satisfactory, Bleaching Sensitivity
Effect of Bleaching Regimen With Different Activation Modes on Color Stability, Surface Roughness, Tooth Sensitivity and Patient Satisfaction
The purpose of this study was to conduct a randomized double-blind clinical trial to examine the efficacy of an in-office bleaching regimen with varied activation modes on color stability, surface roughness, tooth sensitivity…
- Conditions
- Bleaching; Satisfactory, Bleaching Sensitivity, Bleaching Efficacy
- Trial name
- NCT07493941
- Testing
- 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with Laser Activation, 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with LED/Light Activation, 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) - Chemical Activation Only
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tanta University
Tooth Discoloration, Tooth Staining
Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized Nightguards
This randomized, double-blind, split-mouth clinical trial evaluates the effectiveness of at-home dental bleaching using customized nightguards fabricated by digital (3D-printed CAD-CAM) and conventional methods, with and without…
- Trial name
- NCT07464197
- Testing
- Customized bleaching tray fabrication, Reservoir tray design, Carbamide peroxide 10%
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Dentin Hypersensitivity
Efficacy of a Potassium Nitrate Containing Herbal Mouthwash to a Potassium Oxalate Mouthwash in Dentinal Hypersensitivity
The goal of this clinical trial is to compare the efficacy of potassium nitrate containing herbal mouthwash to potassium oxalate mouthwash in management of dentinal hypersensitivity.
- Trial name
- NCT06627790
- Testing
- Mouthwash preparation
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Hypomineralization Molar Incisor, Hypersensitivity Dentin
Photobiomodulation and New Restorative Material for Teeth With MIH on Control of Hypersensitivity and Longevity
Introduction: Molar incisor hypomineralization (MIH) is a qualitative defect of enamel development that occurs in the mineralization phase. MIH affects one or more permanent molars and, occasionally, permanent incisors.
- Trial name
- NCT06538142
- Testing
- Photobiomodulation + Restoration with Self-cure Composite Resin, Restoration with Self-cure Composite Resin, Photobiomodulation + Restoration with Photopolymerizable Bulk-fill Composite Resin
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dentinal Hypersensitivity, Plaque, Dental
Evaluation of Dental and Periodontal Health After IPR in Patients in Orthodontic Treatment With Clear Aligners
This study aimed to evaluate dental and periodontal health after interproximal enamel reduction and to compare Laser diode (a device used in the Orthodontic Program) and sodium fluoride (often used in the Orthodontic Program and…
- Conditions
- Dentinal Hypersensitivity, Plaque, Dental, Bleeding Gum
- Trial name
- NCT06685016
- Testing
- Evaluation of Dentin hypersensitivity with VAS scale
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Dentin Hypersensitivity
Exposed Hypersensitive Dentin Treated With Fluoride Iontophoresis With Remineralizing Agents
The goal of this clinical trial is to learn if the application of fluoride works to treat patients suffering from dentin hypersensitivity.
- Trial name
- NCT06837779
- Testing
- Fluoride Iontophoresis with Acidulated Phosphate Fluoride, Remineralization with sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Tooth Discoloration, Dentin Sensitivity
Efficacy and Safety Assessment of Experimental Bleaching Agents
Tooth bleaching is widely used to treat the colors of teeth. This study compares the efficiency of two experimental bleaching gels, with and without nanoparticles, and with and without light activation versus two commercial…
- Conditions
- Tooth Discoloration, Dentin Sensitivity, Patient Satisfaction
- Trial name
- NCT06802614
- Testing
- BLEACHING GEL A, 5% NF_TiO2, BLEACHING GEL B
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Dentine Hypersensitivity
Three Different Topically Applied Materials as Non-invasive Treatment of Sensitivity in Permanent Teeth With Molar Incisor Hypomineralization
This clinical study main goal is to investigate the effectiveness of nano hydroxy apatite crystal varnish and potassium nitrate gel as a non invasive approach in managing Dentin Hypersensitivity in MIH-affected teeth.
- Trial name
- NCT07056855
- Testing
- nano hydroxy apatite varnish Intervention (1), Potassium Nitrate Gel, Varnishes, Fluorid
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Discoloration, Tooth Staining
Peroxide Versus Non-Peroxide In-Office Tooth Bleaching
This randomized clinical trial aims to compare the effectiveness of peroxide and non-peroxide in-office tooth bleaching systems.
- Trial name
- BECTS (NCT07818031)
- Testing
- peroxide -based in office tooth bleaching, non-peroxide -based in office tooth bleaching
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Minia University
Dentin Hypersensitivity
Effectiveness of Calcium Silicate and Sodium Fluoride Nanoparticles in The Management of Dentin Hypersensitivity
This study will be performed to assess the effect of inert prepared tooth paste loaded with Calcium Silicate Nanoparticles (CSNPs) and compare it to another one containing Sodium Fluoride Nanoparticles in the management of…
- Trial name
- NCT06557980
- Testing
- toothpaste
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Dentin Sensitivity
A Clinical Study to Assess the Efficacy of a Calcium Sodium Phosphosilicate Toothpaste for the Relief of Dentine Hypersensitivity
The primary purpose of this study is to demonstrate the clinical efficacy of Test Toothpaste in reducing dentin hypersensitivity (DH) to an evaporative (air) stimulus, compared to a sodium fluoride reference toothpaste, after 8…
- Trial name
- NCT07802886
- Testing
- Test Toothpaste, Regular Fluoride Toothpaste
- Where
- United Kingdom
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Desensitizing Agents
Dentin Hypersensitivity in Orthodontic Patients: Triple-Blinded, Randomized Trial of Three Desensitizing Agents.
The effect of desensitizing agents will be studied on dentin hypersensitivity in orthodontic patients.it is a randomized controlled trial. three experimental groups and one placebo group.
- Trial name
- NCT07641322
- Testing
- TOOTH PASTE(NHA), TOOTH PASTE (NOVAMIN), TOOTH PASTE (PROARGIN)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nishtar Medical University
Dentin Hypersensitivity
A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers
The primary purpose of this study is to characterize changes in Oral-Health-Related Quality of Life (OHrQoL), as measured by the Dentin Hypersensitivity Experience Questionnaire (DHEQ) over a 12-month period.
- Trial name
- NCT07337109
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- HALEON