Clinical trials: Sensitive Dentin, open to volunteers
Dentin Hypersensitivity
A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers
The primary purpose of this study is to characterize changes in Oral-Health-Related Quality of Life (OHrQoL), as measured by the Dentin Hypersensitivity Experience Questionnaire (DHEQ) over a 12-month period.
- Trial name
- NCT07337109
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- HALEON
Discolored Teeth
Effect of Prophylaxis Pastes With and Without Desensitizing Agents Prior to In-office Bleaching
To evaluate the effect of prophylaxis pastes with and without desensitizing agents prior to in-office bleaching on color change and tooth sensitivity.
- Trial name
- NCT07770373
- Testing
- Treatment
- Volunteers
- 38 people
- Sponsor
- Cairo University
Dentine Hypersensitivity
Dentine Hypersensitivity Using Dentine Adhesive With Strontium-doped Bioactive Glass-Ceramic
The goal of this clinical trial is to determine whether strontium-doped bioactive glass-ceramic (SBGC)-filled dentine adhesive is effective in relieving dentine hypersensitivity.
- Trial name
- NCT07628712
- Testing
- Strontium-doped bioactive glass-ceramic-filled dentine adhesive, Universal dentine adhesive
- Where
- 2 sites in Hong Kong
- Volunteers
- 142 people
- Sponsor
- The University of Hong Kong
Dental Caries
The Study Aims to Compare the Effectiveness of Mesoporous Bioactive Glass-containing Adhesives vs Conventional Universal Adhesives on the Clinical Performance Composite Restorations Through Promoting Dentin Remineralization After Selective Caries Removal Over a Two-year Follow-up
a two-year, double-blind, randomized controlled trial evaluates the effectiveness of a bioactive glass adhesive (Hi-Bond Universal) versus a conventional adhesive (OptiBond Universal) in Class II carious lesions.
- Trial name
- NCT06990945
- Testing
- Hi-Bond Universal Adhesive, OptiBond Universal Adhesive
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Dentin Sensitivity
Effect of an Experimental Cannabidiol Gel on Tooth Sensitivity
The goal of this clinical trial will be to evaluate the effect applying an experimental gel based on cannabidiol oil (CBD) on tooth sensitivity induced by tooth bleaching with 35% hydrogen peroxide (HP).
- Trial name
- NCT07027566
- Testing
- Potassium nitrate and sodium fluoride, Cannabidiol (CBD) Gel, Natrosol 4% Gel
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- Universidade Federal do Para
Dentin Sensitivity, Dentine Hypersensitivity, Tooth Sensitivity
Comparative Efficacy of Laser Systems and Fluoride in Managing Dentinal Hypersensitivity: RCT
This randomized controlled clinical trial aims to compare the effectiveness of Erbium laser (2940 nm), Diode laser (650 nm), combination Diode laser with fluoride varnish, and fluoride varnish alone in treating dentinal…
- Trial name
- DHLT (NCT07141576)
- Testing
- Erbium laser (2940 nm): Infrared light energy, Diode laser (650 nm): Visible red light energy, Fluoride varnish
- Volunteers
- 96 people
- Sponsor
- Cairo University
Dentin Desensitizing Agents
Dentin Hypersensitivity in Orthodontic Patients: Triple-Blinded, Randomized Trial of Three Desensitizing Agents.
The effect of desensitizing agents will be studied on dentin hypersensitivity in orthodontic patients.it is a randomized controlled trial. three experimental groups and one placebo group.
- Trial name
- NCT07641322
- Testing
- TOOTH PASTE(NHA), TOOTH PASTE (NOVAMIN), TOOTH PASTE (PROARGIN)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nishtar Medical University
Dentine Hypersensitivity
Three Different Topically Applied Materials as Non-invasive Treatment of Sensitivity in Permanent Teeth With Molar Incisor Hypomineralization
This clinical study main goal is to investigate the effectiveness of nano hydroxy apatite crystal varnish and potassium nitrate gel as a non invasive approach in managing Dentin Hypersensitivity in MIH-affected teeth.
- Trial name
- NCT07056855
- Testing
- nano hydroxy apatite varnish Intervention (1), Potassium Nitrate Gel, Varnishes, Fluorid
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bleaching; Satisfactory, Bleaching Sensitivity
Effect of Bleaching Regimen With Different Activation Modes on Color Stability, Surface Roughness, Tooth Sensitivity and Patient Satisfaction
The purpose of this study was to conduct a randomized double-blind clinical trial to examine the efficacy of an in-office bleaching regimen with varied activation modes on color stability, surface roughness, tooth sensitivity…
- Conditions
- Bleaching; Satisfactory, Bleaching Sensitivity, Bleaching Efficacy
- Trial name
- NCT07493941
- Testing
- 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with Laser Activation, 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with LED/Light Activation, 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) - Chemical Activation Only
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tanta University
Dentin Hypersensitivity
Exposed Hypersensitive Dentin Treated With Fluoride Iontophoresis With Remineralizing Agents
The goal of this clinical trial is to learn if the application of fluoride works to treat patients suffering from dentin hypersensitivity.
- Trial name
- NCT06837779
- Testing
- Fluoride Iontophoresis with Acidulated Phosphate Fluoride, Remineralization with sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Non-Carious Cervical Lesions (NCCLs), Dentin Hypersensitivity
Evaluation of Different Non-Invasive Methods in the Treatment of Dentin Hypersensitivity Associated With Non-Carious Cervical Lesions: A Split-Mouth Clinical Study
The aim of this split-mouth clinical study is to compare the effectiveness of D Blue diode laser application and ProSylc bioactive glass powder application in reducing dentin hypersensitivity in patients with non-carious cervical…
- Trial name
- NCCL-DH (NCT07648147)
- Testing
- D Blue Diode Laser, ProSylc Bioactive Glass Powder
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Cukurova University
Dentin Caries
Evaluation of the Effect of Flowable Composites on Postoperative Sensitivity in Class I Restorations.
The aim of this study is to evaluate the effect of flowable conventional and bulk-fill composites on postoperative sensitivity in class I cavities over long-term follow-up.
- Trial name
- NCT07343050
- Testing
- Dental restorations
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Dentin Hypersensitivity
Evaluation of the Combined Effect of Bioactive Toothpastes, Desensitizing Agents and Er-YAG Laser on Dentin Hypersensitivity: an In-Vivo Study
Here's the revised version with the corrected treatment and follow-up session schedule: --- The aim of this clinical trial is to evaluate the effectiveness of bioactive toothpastes, desensitizing agents, and Er-YAG laser…
- Trial name
- NCT06854068
- Testing
- laser treatment, application of desensitizing agent
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ege University
Post-operative Sensitivity, Dentin Hypersensitivity
Gluma Compared With Bonding Agent for Post-operative Sensitivity Following Composite Restorations
The aim of this study is to compare the effectiveness of Gluma desensitizer in reducing post-operative sensitivity following composite restorations in posterior teeth.
- Conditions
- Post-operative Sensitivity, Dentin Hypersensitivity, Dental Caries, Tooth Sensitivity After Composite Restorations
- Trial name
- NCT07188142
- Testing
- Drug/Agent: Gluma Desensitizer, Drug/Agent: No desensitizer (Control)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Beenish Hassan
Hypersensitivity Dentin, Fluoride Varnishes
Effect of Fluoride Varnish Formulation on the Management of Dentin Hypersensitivity
This randomized controlled clinical trial aims to determine whether different fluoride varnish formulations reduce dentin hypersensitivity (DH) in young adults diagnosed with DH.
- Trial name
- NCT07286344
- Testing
- Aqueous fluoride varnish, 9,500 ppm NaF, Resin/rosin-based varnish, 22,600 ppm NaF
- Where
- Chile
- Volunteers
- 92 people
- Sponsor
- University of Concepcion, Chile
Dentine Hypersensitivity
Neurological Responses in Patients with Dentine Hypersensitivity
Dentine hypersensitivity (also known as sensitive teeth) is a common dental condition in which the dentine, a layer of sensitive hard tissue under the enamel of the teeth, becomes exposed making the teeth sensitive to stimuli…
- Trial name
- NCT06633627
- Testing
- Recording of brain activity using electroencephalography (EEG)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Dentin Hypersensitivity, Erosive Tooth Wear
Multi-site Study to Look at Tooth Wear and Tooth Sensitivity and the Risk Factors Associated.
The goal of this observational study is to learn about tooth wear and tooth sensistivity and reasons for these conditions in five locations throughout the United States.
- Trial name
- NCT07195357
- Testing
- epidemiological
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- Indiana University
Tooth Sensitivity
The Effect of Bleaching Application Mode on Bleaching-induced Tooth Sensitivity.
The aim of this study is to evaluate the effect of single versus multiple application protocols for in-office dental bleaching using two different bleaching gels (Pola Office Plus, SDI, 37.5% HP and Opalescence Boost, Ultradent…
- Trial name
- NCT07173296
- Testing
- Opalescence XTra Boost 40% HP, Pola Office Plus 37.5% HP
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dentin Sensitivity
A Clinical Study to Assess the Efficacy of a Calcium Sodium Phosphosilicate Toothpaste for the Relief of Dentine Hypersensitivity
The primary purpose of this study is to demonstrate the clinical efficacy of Test Toothpaste in reducing dentin hypersensitivity (DH) to an evaporative (air) stimulus, compared to a sodium fluoride reference toothpaste, after 8…
- Trial name
- NCT07802886
- Testing
- Test Toothpaste, Regular Fluoride Toothpaste
- Where
- United Kingdom
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- HALEON
Tooth Bleaching, Pain
Effects of an Experimental Propolis Gel on Tooth Sensitivity Control and Post-bleaching Color Change: a Randomized Clinical Trial
This randomized, parallel, double-blind, placebo-controlled clinical study aims to investigate the effects of an experimental 0.5% propolis gel on controlling tooth sensitivity and discoloration after in-office dental bleaching.
- Conditions
- Tooth Bleaching, Pain, Dentin Desensitizing Agents
- Trial name
- NCT07569276
- Testing
- Propolis gel, KF2- Potassium nitrate
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Universidade Federal do Para