Clinical trials: Sensitivity, Tooth
Dentin Sensitivity, Hypersensitivity
A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH
Dentin hypersensitivity (DH) is defined as sharp pain of a shorter duration arise from exposed dentin in response to several chemicals and thermal or tactile stimuli that cannot be ascribed to other dental defects".
- Conditions
- Dentin Sensitivity, Hypersensitivity, Cervical Lesion
- Trial name
- NCT06463938
- Testing
- Active comparator, Experimental group, Combination of laser and paste
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Sensitivity, Tooth
Efficacy of a Desensitizing Agent During In-Office Bleaching
The main objective of this study is to evaluate if the use of a desensitizing agent (UltraEZ) during in-office bleaching treatment is effective in reducing tooth sensitivity , as well as doesn't affect the degree of tooth…
- Trial name
- NCT07355647
- Testing
- UltraEZ
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Molar Incisor Hypomineralization
HYPERSENSITIVITY IN MOLAR INCISOR HYPOMINERALISATION USING LOW LEVEL LASER IN CHILDREN
Molar Incisor Hypomineralisation (MIH) is a qualitative defect of enamel that shows asymmetrically involvement of one to four on first permanent molars (FPM) with or without incisor teeth involvement.
- Trial name
- NCT06154733
- Testing
- Photobiomodulation usinf low level laser therapy, Resin-based sealant, Glass ionomer sealant
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dentin Sensitivity
A Clinical Study to Evaluate the Anti-Sensitivity Effect of a Calcium Sodium Phosphosilicate Toothpaste in a Population of Dentin Hypersensitivity Sufferers
The aim of this study is to confirm the clinical dentin hypersensitivity (DH) efficacy of a 5 percent (%) calcium sodium phosphosilicate (CSPS) toothpaste.
- Trial name
- NCT06378008
- Testing
- CSPS toothpaste, Regular fluoride toothpaste (Crest Cavity Protection)
- Where
- Canada
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Hypersensitivity
Exposed Hypersensitive Dentin Treated With Fluoride Iontophoresis With Remineralizing Agents
The goal of this clinical trial is to learn if the application of fluoride works to treat patients suffering from dentin hypersensitivity.
- Trial name
- NCT06837779
- Testing
- Fluoride Iontophoresis with Acidulated Phosphate Fluoride, Remineralization with sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Tooth Bleaching, Low-level Laser Therapy
Effect of Low-level Laser Therapy on Post-bleaching Sensitivity and Color Change
Objective: The objective of this clinical study was to evaluate low-level laser (LLL) therapy in tooth sensitivity and in effecting color change after in-officer bleaching treatment across three weeks of treatment.
- Conditions
- Tooth Bleaching, Low-level Laser Therapy, Dentin Sensitivity, Clinical Trial
- Trial name
- NCT03514290
- Testing
- Low-lever laser, Tooth bleaching
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dentine Hypersensitivity
Efficacy of Miswak Extract Toothpaste as Compared Potassium Nitrate in The Management of Dentinal Hypersensitivity
The study will be a single-center, longitudinal, triple-masked (for participants, operators, and statistician), equal ratio, randomized non-crossover design.
- Trial name
- NCT04179994
- Testing
- Miswak extract-containing toothpaste, Potassium nitrates-containing toothpaste
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Saudi Arabia
Class II Dental Caries, Sensitivity, Tooth
Post-operative Sensitivity in Composite Restorations
Participants will be divided into groups. In group A, Composite restoration done using oblique incremental technique. In group B, Bulk-fill technique was used.
- Trial name
- NCT06092567
- Testing
- Group A ( Oblique Incremental Placement Technique), Group B (Bulk-fill Placement technique)
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Dentin Hypersensitivity
Efficacy of a Potassium Nitrate Containing Herbal Mouthwash to a Potassium Oxalate Mouthwash in Dentinal Hypersensitivity
The goal of this clinical trial is to compare the efficacy of potassium nitrate containing herbal mouthwash to potassium oxalate mouthwash in management of dentinal hypersensitivity.
- Trial name
- NCT06627790
- Testing
- Mouthwash preparation
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Dentine Hypersensitivity
Meta-analysis of Stannous Fluoride Dentifrice and the Effects on Dentine Hypersensitivity
The aim of this 11 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) on dentine hypersensitivity versus a positive or negative control dentifrice.
- Trial name
- NCT04005417
- Testing
- Stannous fluoride dentifrice, Positive control dentifrice, Negative control dentifrice
- Where
- United States
- Volunteers
- 1,036 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentine Hypersensitivity
Efficacy of Novel Titania Nanoparticles Enriched Mouth Wash in Treating Dentine Hypersensitivity
Randomized Clinical trial to compare the reduction in dentin hypersensitivity after incorporating biogenically fabricated titania nanoparticles enriched Mouth Wash and Conventional Mouth Wash.Participants ranging between 20-50…
- Trial name
- NCT06790953
- Testing
- Group- A Conventional Sensed Mouth Wash, Group-B Novel Titania nanoparticles enriched Mouth Wash
- Where
- Pakistan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Medicaments Substances in Therapeutic Use
Etodolac and Post-bleaching Sensitivity
Objectives: This study will determine the effectiveness of preemptive administration of etodolac on risk and intensity of tooth sensitivity caused by in-office bleaching using 35% hydrogen peroxide.
- Trial name
- NCT02881619
- Testing
- Etodolac
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Flavia Pardo Salata Nahsan
Dentin Hypersensitivity, Dentin Sensitivity
Fluoride Varnish X Glass Ionomer Sealant on Cervical Dentin Hypersensitivity
Dentin hypersensitivity (DH) can be defined as acute, short-duration pain from open dentin tubules in exposed dentin. The symptom of DH is subjective and varies from patient to patient and may present as mild discomfort or as a…
- Trial name
- NCT04591444
- Testing
- Fluoride Varnish, Glass Ionomer Sealant
- Where
- Brazil
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Tooth Discoloration
Clinical Efficacy of In-office Bleaching With Different Concentrations of Hydrogen Peroxide
Objective: The study evaluated the longevity, effectiveness, sensitivity and impact on the oral health-related quality of life of in-office dental bleaching using low, medium, and high concentrate hydrogen peroxide.
- Trial name
- NCT06700434
- Testing
- Bleaching treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gazi University
Hypersensitivity Dentin
Effectiveness of the Use of Desensitizing Dentifrices Based on Nanocrystals of Hydroxyapatite / 5% Potassium Nitrate / 1450ppm Sodium Monofluorophosphate and Potassium Nitrate 5% / 1426ppm Sodium Floride in the Treatment of Dentine Hypersensitivity. Test Randomized Clinical
Background: Currently, periodontal treatment, both surgical and non-surgical, leaves sequelae in the vast majority of patients, dentine hypersensitivity (HSD) is one of the most important.
- Trial name
- NCT04156152
- Testing
- DEENSIBILIZING TOOTHPASTE BASED ON NANOCRISTALS OF HYDROXIAPATITA / 5% POTASSIC NITRATE / SODIUM MONOFluORPHOSPHATE 1450 PARTS PER MILLION, 5% POTASSIC NITRATE / SODIUM FLUORIDE 1426 PARTS PER MILLION TOOTHPASTE
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Dentin Sensitivity
Clinical Benefit of a Mouthrinse for the Treatment of Dentine Hypersensitivity
This study is to evaluate the benefit and tolerability of a Mouthrinse (IQP-OLP-101) in the treatment of dentine hypersensitivity.
- Trial name
- NCT03232255
- Testing
- Mouthrinse (IQP-OLP-101)
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Tooth Discoloration, Dentin Sensitivity
Efficacy and Safety Assessment of Experimental Bleaching Agents
Tooth bleaching is widely used to treat the colors of teeth. This study compares the efficiency of two experimental bleaching gels, with and without nanoparticles, and with and without light activation versus two commercial…
- Conditions
- Tooth Discoloration, Dentin Sensitivity, Patient Satisfaction
- Trial name
- NCT06802614
- Testing
- BLEACHING GEL A, 5% NF_TiO2, BLEACHING GEL B
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Dentin Hypersensitivity, Non-carious Cervical Lesions, Bioactive Glass Air Polishing, S-PRG, Dentin Hypersensitivity
Effectiveness of Resin-Based Desensitizer and Laser, Compared to Fluoride Varnish in Management of Dentine Hypersensitivity in Non-carious Cervical Lesions
84 patients who fulfill the inclusion criteria will be enrolled to the study. For every patient a tooth of complain which fulfill the inclusion criteria will be selected, so the total number of included teeth will be 84 teeth.
- Conditions
- Dentin Hypersensitivity, Non-carious Cervical Lesions, Bioactive Glass Air Polishing, S-PRG, Dentin Hypersensitivity, Dentin Desensitizing Agents, Desensitization
- Trial name
- NCT07113847
- Testing
- Resin-Based Desensitizer, Laser Desensitizer, Fluoride-Based Desensitizer
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Dentin Sensitivity
Impact of Long Term Management of Dentine Hypersensitivity (DH) With a Daily Use Anti-sensitivity Toothpaste on the Quality of Life Related to Oral Health
This multicentre, non-comparative design study will monitor the impact of long term management of DH with daily use of a sensitivity toothpaste on the quality of life of a population of sensitivity sufferers.
- Trial name
- NCT02752958
- Testing
- stannous fluoride
- Where
- 2 sites in United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Molar Incisor Hypomineralization
Interventions to Control Hypersensitivity Pain in Teeth With Insisive Molar Hypomineralization
Molar incisor hypomineralization (MIH) manifests as a qualitative, demarcated defect in tooth enamel of systemic origin, predominantly affecting one or more permanent first molars, and potentially extending to the incisors.
- Trial name
- LBIARHMI (NCT06426108)
- Testing
- Fluoride Varnishes, Low-Intensity Laser 1J, Low-Intensity Laser 2J
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo